| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vandetanib perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Vandetanib_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.155352 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.11053 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0879554 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0845137 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0794068 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0727835 |
| FN1 | fibronectin 1 | 0.0721792 |
| CANX | calnexin | 0.057731 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0564478 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0545312 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0530175 |
| NDRG1 | N-myc downstream regulated 1 | 0.0498875 |
| PGK1 | phosphoglycerate kinase 1 | 0.0477316 |
| FNDC3B | fibronectin type III domain containing 3B | 0.047369 |
| GOLGA4 | golgin A4 | 0.0444833 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0442236 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0435478 |
| ASPH | aspartate beta-hydroxylase | 0.0430062 |
| FTL | ferritin, light polypeptide | 0.0424765 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0419927 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0376242 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0371113 |
| CALR | calreticulin | 0.036185 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0360328 |
| ZNF292 | zinc finger protein 292 | 0.0358434 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0356578 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0350857 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0349403 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0340235 |
| ARRDC3 | arrestin domain containing 3 | 0.0336749 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.033163 |
| UBC | ubiquitin C | 0.0324615 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0322244 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0320895 |
| FAM13A | family with sequence similarity 13, member A | 0.0315995 |
| PCBP2 | poly(rC) binding protein 2 | 0.0314054 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0313245 |
| RNF145 | ring finger protein 145 | 0.0312997 |
| SLMAP | sarcolemma associated protein | 0.0311524 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0307213 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0301835 |
| MYO6 | myosin VI | 0.0299967 |
| CCNL1 | cyclin L1 | 0.029838 |
| RBM39 | RNA binding motif protein 39 | 0.0292508 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.02921 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0287684 |
| SPAG9 | sperm associated antigen 9 | 0.0285326 |
| TFG | TRK-fused gene | 0.0280433 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0276869 |
| HMGB2 | high mobility group box 2 | 0.027569 |
| FAM3C | family with sequence similarity 3, member C | 0.0275514 |
| S100A6 | S100 calcium binding protein A6 | 0.0270971 |
| MSN | moesin | 0.0270523 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0266937 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0261191 |
| PTK2 | protein tyrosine kinase 2 | 0.026018 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0259997 |
| UPP1 | uridine phosphorylase 1 | 0.0258618 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0256722 |
| LDHA | lactate dehydrogenase A | 0.0254439 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0251975 |
| RTN4 | reticulon 4 | 0.0251039 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0249859 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0249584 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0248435 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0247405 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0245225 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0240636 |
| RPLP0 | ribosomal protein, large, P0 | 0.023679 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0235355 |
| POTEF | POTE ankyrin domain family, member F | 0.0233723 |
| NCKAP1 | NCK-associated protein 1 | 0.0232776 |
| ANXA1 | annexin A1 | 0.023041 |
| MATR3 | matrin 3 | 0.0230124 |
| CCNI | cyclin I | 0.0228722 |
| RYBP | RING1 and YY1 binding protein | 0.022713 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0226397 |
| TNPO1 | transportin 1 | 0.022567 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0222515 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0220911 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0220574 |
| ANXA5 | annexin A5 | 0.0218882 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0218281 |
| OGA | O-GlcNAcase | 0.0218246 |
| PEG10 | paternally expressed 10 | 0.0216748 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0216228 |
| TMSB4X | thymosin beta 4, X-linked | 0.0211326 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0210231 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0209709 |
| PTMA | prothymosin, alpha | 0.020874 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0207934 |
| ZNF148 | zinc finger protein 148 | 0.0207493 |
| ATP13A3 | ATPase type 13A3 | 0.0207488 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0206269 |
| SET | SET nuclear proto-oncogene | 0.0206179 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0204515 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0203641 |
| CALU | calumenin | 0.0202448 |
| PAPOLA | poly(A) polymerase alpha | 0.0202193 |
| RPS23 | ribosomal protein S23 | 0.0199863 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0557128 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0517538 |
| EFNA5 | ephrin-A5 | -0.0440054 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0377983 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0366148 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0354977 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0352471 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0271464 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0260572 |
| LMO7 | LIM domain 7 | -0.025526 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0224199 |
| NAV2 | neuron navigator 2 | -0.0198333 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0197514 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0191444 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0188945 |
| FBXO32 | F-box protein 32 | -0.0188331 |
| ATXN1 | ataxin 1 | -0.0185422 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0185407 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0184317 |
| RPL35A | ribosomal protein L35a | -0.0180846 |
| GOLGB1 | golgin B1 | -0.0180461 |
| RPLP1 | ribosomal protein, large, P1 | -0.0180174 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0171736 |
| RNF213 | ring finger protein 213 | -0.0169748 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0169359 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0157169 |
| MX2 | MX dynamin-like GTPase 2 | -0.0154709 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0154004 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0152312 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0151778 |
| RIGI | RNA sensor RIG-I | -0.0148299 |
| ETV6 | ets variant 6 | -0.0146364 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0141264 |
| RRBP1 | ribosome binding protein 1 | -0.0138449 |
| CUX1 | cut-like homeobox 1 | -0.013803 |
| S100A9 | S100 calcium binding protein A9 | -0.0136212 |
| H1-0 | H1.0 linker histone | -0.0134466 |
| ATP11A | ATPase, class VI, type 11A | -0.0134356 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0133784 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.012852 |
| RPL36 | ribosomal protein L36 | -0.0127869 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.012646 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0122677 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.012208 |
| RAD51B | RAD51 paralog B | -0.0121802 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0121394 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0121002 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.011907 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0118735 |
| SP100 | SP100 nuclear antigen | -0.0117156 |
| ACTG1 | actin gamma 1 | -0.0114083 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.011382 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0112543 |
| EGFR | epidermal growth factor receptor | -0.0111912 |
| HLA-B | major histocompatibility complex, class I, B | -0.0110541 |
| RAI14 | retinoic acid induced 14 | -0.0110425 |
| EGR1 | early growth response 1 | -0.0110042 |
| MX1 | MX dynamin-like GTPase 1 | -0.0109769 |
| SVIL | supervillin | -0.0109 |
| FNIP1 | folliculin interacting protein 1 | -0.0108995 |
| LMNA | lamin A/C | -0.0108535 |
| PLSCR1 | phospholipid scramblase 1 | -0.0107456 |
| RPS19 | ribosomal protein S19 | -0.0107271 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -0.0106427 |
| NABP1 | nucleic acid binding protein 1 | -0.010538 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0105235 |
| ZNF217 | zinc finger protein 217 | -0.0103511 |
| EHBP1 | EH domain binding protein 1 | -0.0103332 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0102684 |
| RBM47 | RNA binding motif protein 47 | -0.0102148 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0101352 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00993177 |
| HMGB1 | high mobility group box 1 | -0.00991674 |
| VCL | vinculin | -0.00984948 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.00983902 |
| RASAL2 | RAS protein activator like 2 | -0.00980571 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.00972568 |
| FRMD5 | FERM domain containing 5 | -0.00972165 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.00964449 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.00960124 |
| LOXL2 | lysyl oxidase-like 2 | -0.00946624 |
| PATJ | PATJ crumbs cell polarity complex component | -0.00929619 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.00927027 |
| GOLGA3 | golgin A3 | -0.00925363 |
| HOOK3 | hook microtubule-tethering protein 3 | -0.00925212 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00924389 |
| NTN4 | netrin 4 | -0.00923153 |
| RPS17 | ribosomal protein S17 | -0.00918406 |
| SMAD3 | SMAD family member 3 | -0.00909935 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.00907825 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.00905139 |
| PLEC | plectin | -0.00900719 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.00900316 |
| MACC1 | metastasis associated in colon cancer 1 | -0.00896326 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00896072 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00885399 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.00879527 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.00876618 |
| MYO1E | myosin IE | -0.00867987 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.00866681 |
