| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vandetanib perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Vandetanib_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0874271 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0549136 |
| ASPH | aspartate beta-hydroxylase | 0.0392311 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0340335 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0335509 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0332732 |
| USP34 | ubiquitin specific peptidase 34 | 0.0308387 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0294717 |
| PRELID2 | PRELI domain containing 2 | 0.0289045 |
| MCL1 | myeloid cell leukemia 1 | 0.0276062 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0257838 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0255977 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0255614 |
| NBEAL1 | neurobeachin-like 1 | 0.0235201 |
| KYNU | kynureninase | 0.0233962 |
| UBC | ubiquitin C | 0.0233797 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0229462 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0224993 |
| PKM | pyruvate kinase, muscle | 0.0218395 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0214848 |
| ENO1 | enolase 1, (alpha) | 0.0212523 |
| LSAMP | limbic system-associated membrane protein | 0.0208996 |
| RPS23 | ribosomal protein S23 | 0.0204251 |
| SQSTM1 | sequestosome 1 | 0.0204044 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0202647 |
| VIM | vimentin | 0.0201971 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0200002 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0195845 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0195814 |
| PTEN | phosphatase and tensin homolog | 0.0194994 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0194783 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0193502 |
| RPLP0 | ribosomal protein, large, P0 | 0.0190064 |
| TPM3 | tropomyosin 3 | 0.0188211 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0186862 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0186493 |
| GRAMD1B | GRAM domain containing 1B | 0.0184393 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0183313 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0182956 |
| VMP1 | vacuole membrane protein 1 | 0.0181233 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0179133 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0178837 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0178712 |
| FLNB | filamin B, beta | 0.0175215 |
| FNIP1 | folliculin interacting protein 1 | 0.0172256 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0170063 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0166657 |
| STC1 | stanniocalcin 1 | 0.0163132 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0161205 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0160298 |
| PYGL | phosphorylase, glycogen, liver | 0.0158178 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0157765 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0157524 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0156106 |
| ZNF638 | zinc finger protein 638 | 0.0151027 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0150849 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0150838 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0149083 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0148116 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0146291 |
| NDRG1 | N-myc downstream regulated 1 | 0.0146224 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0146094 |
| FMNL2 | formin-like 2 | 0.0145892 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0143347 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0141199 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0140276 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0137444 |
| ACTG1 | actin gamma 1 | 0.0137097 |
| DNER | delta/notch-like EGF repeat containing | 0.0136804 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0135958 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0135587 |
| SET | SET nuclear proto-oncogene | 0.0134995 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0133786 |
| RO60 | Ro60, Y RNA binding protein | 0.0132584 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0132322 |
| GPC6 | glypican 6 | 0.0132193 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0131717 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0131596 |
| MYOF | myoferlin | 0.0131323 |
| MFF | mitochondrial fission factor | 0.0130354 |
| MSN | moesin | 0.012922 |
| KIF5B | kinesin family member 5B | 0.0128164 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0127815 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0126147 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0126012 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.0123838 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0123672 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0122471 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0122436 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0122324 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0121804 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0120442 |
| NBAS | neuroblastoma amplified sequence | 0.0120146 |
| SCFD1 | sec1 family domain containing 1 | 0.0119918 |
| PCBP2 | poly(rC) binding protein 2 | 0.0119 |
| KRT19 | keratin 19, type I | 0.0118913 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.011837 |
| IPO7 | importin 7 | 0.0116868 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0115946 |
| CLTC | clathrin, heavy chain (Hc) | 0.0115161 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.200796 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.109389 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0959261 |
| TMSB10 | thymosin beta 10 | -0.095751 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.062545 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0622896 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0609655 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0592017 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.052157 |
| PDE10A | phosphodiesterase 10A | -0.0517625 |
| SMYD3 | SET and MYND domain containing 3 | -0.0514281 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0457001 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0411732 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0351287 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0350795 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0349627 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.03478 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0335756 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0320982 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.031486 |
| FTL | ferritin, light polypeptide | -0.0300515 |
| NCKAP5 | NCK-associated protein 5 | -0.02957 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.028572 |
| COL5A2 | collagen, type V, alpha 2 | -0.0277323 |
| PCBP3 | poly(rC) binding protein 3 | -0.0275853 |
| GDA | guanine deaminase | -0.0265659 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0265569 |
| RPL35A | ribosomal protein L35a | -0.026531 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0263602 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0242133 |
| DST | dystonin | -0.0238451 |
| YBX3 | Y box binding protein 3 | -0.0235313 |
| KIAA0825 | KIAA0825 | -0.0234381 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0233333 |
| PDE7B | phosphodiesterase 7B | -0.0222877 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.0219365 |
| RTN1 | reticulon 1 | -0.0214484 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0214276 |
| S100A6 | S100 calcium binding protein A6 | -0.0210701 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0208629 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0208331 |
| PTMA | prothymosin, alpha | -0.0204775 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0202182 |
| TBXT | T-box transcription factor T | -0.020159 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0200902 |
| TBC1D19 | TBC1 domain family, member 19 | -0.0198578 |
| PALLD | palladin, cytoskeletal associated protein | -0.0196993 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0191765 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0185996 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0184347 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0183997 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0181467 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0181442 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0181179 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | -0.0180313 |
| RPS3 | ribosomal protein S3 | -0.0179494 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0178112 |
| RPL36 | ribosomal protein L36 | -0.0176995 |
| RPLP1 | ribosomal protein, large, P1 | -0.0172654 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0172426 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | -0.0169952 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0167849 |
| STEAP1B | STEAP family member 1B | -0.0164499 |
| RPL37A | ribosomal protein L37a | -0.0159735 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.01568 |
| RPL13A | ribosomal protein L13a | -0.0155923 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0154971 |
| RPL19 | ribosomal protein L19 | -0.0153883 |
| AFG2A | AFG2 AAA ATPase homolog A | -0.0152904 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0152814 |
| CTSC | cathepsin C | -0.0148409 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.014794 |
| EGR1 | early growth response 1 | -0.0147225 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0147159 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0147011 |
| B2M | beta-2-microglobulin | -0.0144448 |
| RPL12 | ribosomal protein L12 | -0.0144157 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa | -0.0142736 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0140899 |
| AOPEP | aminopeptidase O (putative) | -0.014067 |
| LAMA1 | laminin, alpha 1 | -0.0139573 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0138137 |
| GRB10 | growth factor receptor-bound protein 10 | -0.013667 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.013618 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.0136101 |
| RBM39 | RNA binding motif protein 39 | -0.0135471 |
| FRMD4B | FERM domain containing 4B | -0.0135159 |
| PDE1A | phosphodiesterase 1A, calmodulin-dependent | -0.013434 |
| RPS19 | ribosomal protein S19 | -0.0134036 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.01312 |
| ANTXR1 | anthrax toxin receptor 1 | -0.013098 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0130279 |
| ZNF804A | zinc finger protein 804A | -0.0128451 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0127863 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0127756 |
| PTGR1 | prostaglandin reductase 1 | -0.0127252 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0124351 |
| TXNRD1 | thioredoxin reductase 1 | -0.0122972 |
| HLA-B | major histocompatibility complex, class I, B | -0.0122963 |
| OSMR | oncostatin M receptor | -0.0122544 |
