| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vandetanib perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vandetanib_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.131393 |
| PDE10A | phosphodiesterase 10A | 0.131149 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.1249 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.123532 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.107086 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.10345 |
| INHBA | inhibin, beta A | 0.0972638 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0969911 |
| GOLGA4 | golgin A4 | 0.0868281 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0811554 |
| SCFD1 | sec1 family domain containing 1 | 0.0807796 |
| FAM13A | family with sequence similarity 13, member A | 0.0806364 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0795928 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0788855 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0778026 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0748774 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0741444 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0736454 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0714417 |
| PTGES2 | prostaglandin E synthase 2 | 0.0707696 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0696349 |
| VMP1 | vacuole membrane protein 1 | 0.0677232 |
| STC1 | stanniocalcin 1 | 0.0666248 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.064045 |
| EFNA5 | ephrin-A5 | 0.0632003 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0583617 |
| EGFR | epidermal growth factor receptor | 0.0565051 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.055081 |
| COPA | coatomer protein complex, subunit alpha | 0.0537401 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0529474 |
| PKN2 | protein kinase N2 | 0.0516095 |
| OGA | O-GlcNAcase | 0.0514017 |
| AK1 | adenylate kinase 1 | 0.0510525 |
| CALU | calumenin | 0.0509738 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0508682 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0505602 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0503523 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0493711 |
| SBF2 | SET binding factor 2 | 0.0492924 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0491457 |
| RPS23 | ribosomal protein S23 | 0.0490879 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0488144 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0480524 |
| GOLGB1 | golgin B1 | 0.0480429 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0479886 |
| SET | SET nuclear proto-oncogene | 0.0478421 |
| FBXO11 | F-box protein 11 | 0.0472985 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.047266 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0465357 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0458076 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0457836 |
| PRELID2 | PRELI domain containing 2 | 0.0456483 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0447908 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0445641 |
| RBM39 | RNA binding motif protein 39 | 0.0436407 |
| RORA | RAR-related orphan receptor A | 0.0433494 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0431381 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0426557 |
| FOXP1 | forkhead box P1 | 0.0425859 |
| RPL35A | ribosomal protein L35a | 0.0424838 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0424528 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0420912 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0416466 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0414285 |
| MATR3 | matrin 3 | 0.0413588 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0413532 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0413487 |
| PDE8A | phosphodiesterase 8A | 0.0410593 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0408068 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0404231 |
| APP | amyloid beta (A4) precursor protein | 0.0402676 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0402115 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0401923 |
| USP34 | ubiquitin specific peptidase 34 | 0.0400555 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0390679 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0389875 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0388771 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0387051 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0370336 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0367622 |
| FOXO3 | forkhead box O3 | 0.0362888 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0354769 |
| ATP13A3 | ATPase type 13A3 | 0.0353676 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0351054 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0348638 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0344061 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0335842 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0332867 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.033146 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0327198 |
| RPLP0 | ribosomal protein, large, P0 | 0.0321534 |
| GLG1 | golgi glycoprotein 1 | 0.0319039 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0318794 |
| ATXN1 | ataxin 1 | 0.0317804 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0315552 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0312008 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0307192 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0305472 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0303961 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0300473 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | -0.155831 |
| PTMA | prothymosin, alpha | -0.141697 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.111566 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.109655 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.109345 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.102484 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0978672 |
| RPLP1 | ribosomal protein, large, P1 | -0.0955969 |
| RPS3 | ribosomal protein S3 | -0.0933304 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0911051 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0856316 |
| RPL23 | ribosomal protein L23 | -0.0837651 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0833861 |
| NAV2 | neuron navigator 2 | -0.0830559 |
| RPS16 | ribosomal protein S16 | -0.0801251 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0776281 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0740825 |
| SNX9 | sorting nexin 9 | -0.0733662 |
| ANXA2 | annexin A2 | -0.0666338 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0657847 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0641284 |
| ACTN4 | actinin, alpha 4 | -0.0616195 |
| MT2A | metallothionein 2A | -0.0611074 |
| NUP58 | nucleoporin 58 | -0.0609791 |
| RPL26 | ribosomal protein L26 | -0.0596688 |
| RLF | rearranged L-myc fusion | -0.0568016 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0556505 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0544831 |
| PGK1 | phosphoglycerate kinase 1 | -0.054256 |
| LMO7 | LIM domain 7 | -0.0529779 |
| JUN | jun proto-oncogene | -0.0518437 |
| ITGA6 | integrin, alpha 6 | -0.0501657 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0499928 |
| FN1 | fibronectin 1 | -0.0484729 |
| RTN4 | reticulon 4 | -0.0483906 |
| SQSTM1 | sequestosome 1 | -0.0469094 |
| IREB2 | iron-responsive element binding protein 2 | -0.046168 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0455311 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0451263 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0448905 |
| RYBP | RING1 and YY1 binding protein | -0.0448404 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0447042 |
| RBM25 | RNA binding motif protein 25 | -0.0445925 |
| RPS8 | ribosomal protein S8 | -0.043785 |
| RNF213 | ring finger protein 213 | -0.0432578 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0432427 |
| TNPO1 | transportin 1 | -0.0432205 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0429091 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.042052 |
| MAP4 | microtubule-associated protein 4 | -0.0418659 |
| RPL27A | ribosomal protein L27a | -0.0413458 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0410292 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0408271 |
| UBE2Z | ubiquitin-conjugating enzyme E2Z | -0.0402389 |
| TPI1 | triosephosphate isomerase 1 | -0.0401582 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0390304 |
| RB1 | retinoblastoma 1 | -0.0382672 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0372275 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0366878 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.036571 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0361943 |
| MORF4L2 | mortality factor 4 like 2 | -0.0359636 |
| RPS27A | ribosomal protein S27a | -0.0354064 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0348416 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0346241 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0346055 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0346035 |
| EGR1 | early growth response 1 | -0.0341817 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.034175 |
| SP100 | SP100 nuclear antigen | -0.0339255 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.033872 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0335413 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0332849 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0326867 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0326764 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0319932 |
| AHNAK | AHNAK nucleoprotein | -0.0309074 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0306959 |
| FLNB | filamin B, beta | -0.030692 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0304373 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0301537 |
| LDHA | lactate dehydrogenase A | -0.0301337 |
| STAG2 | stromal antigen 2 | -0.0300174 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0290893 |
| JMJD1C | jumonji domain containing 1C | -0.0287003 |
| MCL1 | myeloid cell leukemia 1 | -0.0284237 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0282791 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0280853 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0279779 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0279032 |
| RPL5 | ribosomal protein L5 | -0.027812 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0278019 |
| ZFR | zinc finger RNA binding protein | -0.0277034 |
| LAMB3 | laminin, beta 3 | -0.0275596 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | -0.0272732 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0272392 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0270207 |
| H1-0 | H1.0 linker histone | -0.0268445 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0265269 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0264213 |
