| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vandetanib perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vandetanib_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LOX | lysyl oxidase | 0.115149 |
| CANX | calnexin | 0.0709372 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0564497 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0552671 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0536329 |
| LMAN1 | lectin, mannose-binding, 1 | 0.048451 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0475383 |
| COG5 | component of oligomeric golgi complex 5 | 0.047233 |
| ZNF292 | zinc finger protein 292 | 0.0471941 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0458888 |
| QKI | QKI, KH domain containing, RNA binding | 0.0458057 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0435148 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.043159 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0431387 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0412775 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0404069 |
| TXNIP | thioredoxin interacting protein | 0.0403933 |
| SDC4 | syndecan 4 | 0.0395362 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0384696 |
| YBX3 | Y box binding protein 3 | 0.0381482 |
| CLEC1B | C-type lectin domain family 1, member B | 0.0380734 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0378917 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0374022 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0373905 |
| ATP13A3 | ATPase type 13A3 | 0.0371844 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0365288 |
| PCBP2 | poly(rC) binding protein 2 | 0.0359765 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0357231 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0355748 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.0350125 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0346473 |
| PGK1 | phosphoglycerate kinase 1 | 0.0344821 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0344499 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0343585 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0343352 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0338331 |
| ARF1 | ADP-ribosylation factor 1 | 0.0335726 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0334706 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | 0.0333097 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0331372 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0330353 |
| COL1A1 | collagen, type I, alpha 1 | 0.0329745 |
| YTHDC1 | YTH domain containing 1 | 0.0328525 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0326628 |
| POLK | polymerase (DNA directed) kappa | 0.0326113 |
| TNPO3 | transportin 3 | 0.0325488 |
| NCK1 | NCK adaptor protein 1 | 0.0324875 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0323862 |
| TMEM41B | transmembrane protein 41B | 0.0320299 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0319912 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0318753 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0316216 |
| PTK2 | protein tyrosine kinase 2 | 0.0314309 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0313368 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0312555 |
| OPTN | optineurin | 0.0310103 |
| FMNL2 | formin-like 2 | 0.0309082 |
| TNPO1 | transportin 1 | 0.0307594 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0306566 |
| CREBBP | CREB binding protein | 0.0302363 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0300391 |
| UBQLN1 | ubiquilin 1 | 0.0299699 |
| GLG1 | golgi glycoprotein 1 | 0.0299313 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | 0.0298287 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | 0.0296751 |
| FNBP1L | formin binding protein 1-like | 0.0293546 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0292649 |
| SETX | senataxin | 0.0291524 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.028983 |
| FAM13A | family with sequence similarity 13, member A | 0.0289733 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0288584 |
| SMAD2 | SMAD family member 2 | 0.0284974 |
| TMEM39A | transmembrane protein 39A | 0.028493 |
| MATR3 | matrin 3 | 0.0284809 |
| MALT1 | MALT1 paracaspase | 0.0281045 |
| MT1X | metallothionein 1X | 0.0278936 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0278772 |
| RBM15 | RNA binding motif protein 15 | 0.0276962 |
| ANXA2 | annexin A2 | 0.0276428 |
| PPA1 | pyrophosphatase (inorganic) 1 | 0.0275496 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0275413 |
| NRXN3 | neurexin 3 | 0.0271039 |
| CLTC | clathrin, heavy chain (Hc) | 0.027002 |
| MYO10 | myosin X | 0.0269558 |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 | 0.0269117 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0268533 |
| CD2AP | CD2-associated protein | 0.0264104 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0263314 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0262781 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.026258 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0262579 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0262055 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0261904 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0261389 |
| STK4 | serine/threonine kinase 4 | 0.0260497 |
| TLK1 | tousled-like kinase 1 | 0.0260232 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase | 0.0259973 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0259053 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0258277 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0257331 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.143818 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.107722 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.101457 |
| FN1 | fibronectin 1 | -0.0832382 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0762926 |
| FTL | ferritin, light polypeptide | -0.0646914 |
| NDRG1 | N-myc downstream regulated 1 | -0.0613497 |
| MT2A | metallothionein 2A | -0.0583059 |
| HMGA2 | high mobility group AT-hook 2 | -0.0565567 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0561795 |
| CDH13 | cadherin 13 | -0.0548707 |
| HLA-C | major histocompatibility complex, class I, C | -0.0546892 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0545961 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0525497 |
| TNS3 | tensin 3 | -0.0512311 |
| ACTG1 | actin gamma 1 | -0.0508035 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0506403 |
| IL6 | interleukin 6 | -0.0485488 |
| SBF2 | SET binding factor 2 | -0.047963 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0462107 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0453304 |
| ENO1 | enolase 1, (alpha) | -0.0442717 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0428602 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0425278 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0417834 |
| POTEF | POTE ankyrin domain family, member F | -0.0410915 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0408624 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0407395 |
| RPS16 | ribosomal protein S16 | -0.0384634 |
| FOSL1 | FOS-like antigen 1 | -0.0376733 |
| GLIS3 | GLIS family zinc finger 3 | -0.0372614 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0361711 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0352396 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0349872 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0348487 |
| RPL28 | ribosomal protein L28 | -0.033907 |
| ANXA1 | annexin A1 | -0.0334121 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0330034 |
| VEGFA | vascular endothelial growth factor A | -0.0327781 |
| S100A10 | S100 calcium binding protein A10 | -0.0326881 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0324377 |
| TPM1 | tropomyosin 1 (alpha) | -0.0324255 |
| VEGFC | vascular endothelial growth factor C | -0.032267 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0319867 |
| B2M | beta-2-microglobulin | -0.0318621 |
| RNF145 | ring finger protein 145 | -0.0311975 |
| MYADM | myeloid-associated differentiation marker | -0.0303608 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0299614 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0298244 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0297692 |
| CDK13 | cyclin-dependent kinase 13 | -0.0293156 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0288415 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0286023 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0285127 |
| RPL36 | ribosomal protein L36 | -0.0283841 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.028376 |
| PRSS23 | protease, serine, 23 | -0.027847 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0277363 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0274507 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0271772 |
| RPS12 | ribosomal protein S12 | -0.0271622 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0271474 |
| EGFR | epidermal growth factor receptor | -0.0266993 |
| MRTFA | myocardin related transcription factor A | -0.0266053 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0265553 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0265258 |
| LOXL2 | lysyl oxidase-like 2 | -0.0259174 |
| NABP1 | nucleic acid binding protein 1 | -0.0257842 |
| SECISBP2L | SECIS binding protein 2-like | -0.0255019 |
| PFN1 | profilin 1 | -0.0253468 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0252137 |
| RUNX1 | runt-related transcription factor 1 | -0.025185 |
| RPL23 | ribosomal protein L23 | -0.025181 |
| RPL19 | ribosomal protein L19 | -0.0250672 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0247622 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.0247557 |
| CALD1 | caldesmon 1 | -0.0244005 |
| IL6ST | interleukin 6 signal transducer | -0.0243575 |
| TUBA1B | tubulin, alpha 1b | -0.0242271 |
| FRMD4A | FERM domain containing 4A | -0.0242009 |
| EGR1 | early growth response 1 | -0.0241157 |
| WDR43 | WD repeat domain 43 | -0.0239378 |
| DST | dystonin | -0.0238335 |
| ROS1 | ROS proto-oncogene 1 , receptor tyrosine kinase | -0.0236864 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0236634 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0236568 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.0236188 |
| IPO9 | importin 9 | -0.023608 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0235133 |
| CBX3 | chromobox homolog 3 | -0.0234864 |
| PTGES2 | prostaglandin E synthase 2 | -0.0234832 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.023422 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0230223 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0228915 |
| WWOX | WW domain containing oxidoreductase | -0.0228718 |
| PLCB4 | phospholipase C, beta 4 | -0.0227251 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0226087 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0226007 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.022492 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0223933 |
