| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vandetanib perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vandetanib_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0516304 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0486545 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0472875 |
| NUP58 | nucleoporin 58 | 0.0471491 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0428936 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0426627 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0402701 |
| HELZ | helicase with zinc finger | 0.0393754 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0374008 |
| TXNRD1 | thioredoxin reductase 1 | 0.0367894 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0349156 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0346795 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | 0.0343544 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0335895 |
| RAB6A | RAB6A, member RAS oncogene family | 0.033117 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0327501 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0318484 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0318302 |
| RNF145 | ring finger protein 145 | 0.0315535 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0312754 |
| MATR3 | matrin 3 | 0.0311933 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0308488 |
| RDX | radixin | 0.0304346 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0303871 |
| CWF19L2 | CWF19-like 2, cell cycle control (S. pombe) | 0.0302017 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0296505 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0295904 |
| SCAI | suppressor of cancer cell invasion | 0.029565 |
| TNPO3 | transportin 3 | 0.0292063 |
| KIF5B | kinesin family member 5B | 0.0290032 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.0289322 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0289055 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 | 0.028853 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0282415 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0269274 |
| YTHDC1 | YTH domain containing 1 | 0.0268246 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0265391 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.0263269 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0261247 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0258942 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0256012 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0254747 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0254508 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0254022 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0253816 |
| FMNL2 | formin-like 2 | 0.0253191 |
| GAPVD1 | GTPase activating protein and VPS9 domains 1 | 0.0251784 |
| CAB39 | calcium binding protein 39 | 0.025125 |
| ZNF292 | zinc finger protein 292 | 0.0248062 |
| FAF2 | Fas associated factor family member 2 | 0.0247112 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.02471 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0246633 |
| NUP153 | nucleoporin 153kDa | 0.0246627 |
| ANLN | anillin, actin binding protein | 0.0246258 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0246012 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0245607 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0241431 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0240343 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0238095 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0238072 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0237681 |
| CREBRF | CREB3 regulatory factor | 0.0235381 |
| RASA3 | RAS p21 protein activator 3 | 0.0234854 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.023445 |
| ZNF670 | zinc finger protein 670 | 0.0233881 |
| TMEM39A | transmembrane protein 39A | 0.0233485 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0231419 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0229583 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.02285 |
| KLHL24 | kelch-like family member 24 | 0.0227201 |
| JMJD1C | jumonji domain containing 1C | 0.0227016 |
| KIZ | kizuna centrosomal protein | 0.0226992 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0225789 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0225767 |
| DCAF1 | DDB1 and CUL4 associated factor 1 | 0.0223987 |
| ATP13A3 | ATPase type 13A3 | 0.0223712 |
| USP12 | ubiquitin specific peptidase 12 | 0.0223283 |
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.0221856 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0221823 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0220703 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0219439 |
| PTGES2 | prostaglandin E synthase 2 | 0.021867 |
| UBAC2 | UBA domain containing 2 | 0.0218377 |
| OGA | O-GlcNAcase | 0.0218308 |
| DTNA | dystrobrevin, alpha | 0.0218185 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0217724 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0217334 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0217135 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.0217 |
| CCDC93 | coiled-coil domain containing 93 | 0.0216195 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.021587 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0214947 |
| DAZAP1 | DAZ associated protein 1 | 0.0213708 |
| PANK3 | pantothenate kinase 3 | 0.0212928 |
| TNPO1 | transportin 1 | 0.0212257 |
| RECQL | RecQ helicase-like | 0.0211985 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0211038 |
| ZNF207 | zinc finger protein 207 | 0.0210788 |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 | 0.0209671 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0208202 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.178134 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.116869 |
| PTMA | prothymosin, alpha | -0.103705 |
| TMSB10 | thymosin beta 10 | -0.102027 |
| LDHA | lactate dehydrogenase A | -0.0925764 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0778686 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0716861 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0659341 |
| RPL35A | ribosomal protein L35a | -0.0640375 |
| ANKRD11 | ankyrin repeat domain 11 | -0.060961 |
| PTK2 | protein tyrosine kinase 2 | -0.0577473 |
| POTEF | POTE ankyrin domain family, member F | -0.0547566 |
| PDE8A | phosphodiesterase 8A | -0.05182 |
| DST | dystonin | -0.0508656 |
| RORA | RAR-related orphan receptor A | -0.0508123 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0492335 |
| ANXA2 | annexin A2 | -0.0489891 |
| RAD51B | RAD51 paralog B | -0.0482473 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0479895 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0477019 |
| HMGA2 | high mobility group AT-hook 2 | -0.0474332 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0465439 |
| GNAS | GNAS complex locus | -0.0465186 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0465146 |
| RAI14 | retinoic acid induced 14 | -0.0457695 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0447492 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0445841 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0441494 |
| FLNB | filamin B, beta | -0.0429549 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0426442 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0419994 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0418378 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0410369 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0400888 |
| IGF2 | insulin-like growth factor 2 | -0.0394576 |
| FMN1 | formin 1 | -0.0393359 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0391557 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0389438 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0387061 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0383742 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0383391 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0382879 |
| RPL15 | ribosomal protein L15 | -0.0381438 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0379041 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0375252 |
| INTS6 | integrator complex subunit 6 | -0.0373284 |
| RPL31 | ribosomal protein L31 | -0.0371876 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0371348 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0370831 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0370011 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0367268 |
| AHNAK | AHNAK nucleoprotein | -0.0361678 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0357331 |
| RPS17 | ribosomal protein S17 | -0.0350879 |
| ZNF609 | zinc finger protein 609 | -0.0349212 |
| RPL23 | ribosomal protein L23 | -0.0348682 |
| PRKCA | protein kinase C, alpha | -0.0348306 |
| ACTG1 | actin gamma 1 | -0.0345842 |
| CD44 | CD44 molecule (Indian blood group) | -0.0342427 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0341288 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0340374 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0337532 |
| NAV2 | neuron navigator 2 | -0.0335411 |
| S100A9 | S100 calcium binding protein A9 | -0.0335219 |
| RPS8 | ribosomal protein S8 | -0.0329443 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0327614 |
| CCDC91 | coiled-coil domain containing 91 | -0.0327488 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0325789 |
| RPS12 | ribosomal protein S12 | -0.0324107 |
| RPL26 | ribosomal protein L26 | -0.032272 |
| OSMR | oncostatin M receptor | -0.0322114 |
| RPLP1 | ribosomal protein, large, P1 | -0.0321917 |
| MKI67 | marker of proliferation Ki-67 | -0.0320596 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0317926 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0315925 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0313516 |
| ATM | ATM serine/threonine kinase | -0.0311408 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0310169 |
| BPTF | bromodomain PHD finger transcription factor | -0.0309539 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0308888 |
| RPS25 | ribosomal protein S25 | -0.0308327 |
| KLF12 | Kruppel-like factor 12 | -0.0304093 |
| ATXN1 | ataxin 1 | -0.0303551 |
| B2M | beta-2-microglobulin | -0.0303097 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0300887 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0300515 |
| RPL35 | ribosomal protein L35 | -0.0299653 |
| GPC6 | glypican 6 | -0.0297232 |
| SYCP2 | synaptonemal complex protein 2 | -0.0291395 |
| RPS23 | ribosomal protein S23 | -0.0290276 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0289599 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0287855 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0286075 |
| RAB33B | RAB33B, member RAS oncogene family | -0.0285716 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0280885 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0279147 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0278715 |
| PDCD6IP | programmed cell death 6 interacting protein | -0.0277552 |
| RSF1 | remodeling and spacing factor 1 | -0.0277464 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0277462 |
