Vasculitis Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A vascular disease that is characterized by inflammation of the blood vessels. (Human Disease Ontology, DOID_865)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D014657
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Genes

685 genes/proteins associated with the disease Vasculitis from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 2.88009
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 2.88009
TNF tumor necrosis factor 2.48152
IL6 interleukin 6 2.48087
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.40275
BCL2 B-cell CLL/lymphoma 2 2.39901
BAX BCL2-associated X protein 2.37211
CAT catalase 2.35834
IL1B interleukin 1, beta 2.33332
VEGFA vascular endothelial growth factor A 2.30256
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.28811
CCL2 chemokine (C-C motif) ligand 2 2.25592
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.24414
TP53 tumor protein p53 2.24298
EDN1 endothelin 1 2.24281
IL10 interleukin 10 2.21195
IFNG interferon, gamma 2.18282
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.1752
TGFB1 transforming growth factor, beta 1 2.16798
CASP8 caspase 8, apoptosis-related cysteine peptidase 2.14026
SOD2 superoxide dismutase 2, mitochondrial 2.1336
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.12576
CXCL8 chemokine (C-X-C motif) ligand 8 2.11529
DDIT3 DNA-damage-inducible transcript 3 2.11424
JUN jun proto-oncogene 2.10125
IL4 interleukin 4 2.09997
CASP9 caspase 9, apoptosis-related cysteine peptidase 2.09603
NOS2 nitric oxide synthase 2, inducible 2.09381
FAS Fas cell surface death receptor 2.09262
MAPK3 mitogen-activated protein kinase 3 2.08296
MAPK1 mitogen-activated protein kinase 1 2.07429
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.06027
FOS FBJ murine osteosarcoma viral oncogene homolog 2.04371
ICAM1 intercellular adhesion molecule 1 2.03952
VCAM1 vascular cell adhesion molecule 1 2.01979
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 2.01567
BCL2L1 BCL2-like 1 2.00745
NPPB natriuretic peptide B 1.98167
HMOX1 heme oxygenase 1 1.97799
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.9604
FGF2 fibroblast growth factor 2 (basic) 1.92042
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.90607
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.90392
ARC activity-regulated cytoskeleton-associated protein 1.89552
PARP1 poly (ADP-ribose) polymerase 1 1.89311
GSTP1 glutathione S-transferase pi 1 1.88819
SPP1 secreted phosphoprotein 1 1.87759
TIMP1 TIMP metallopeptidase inhibitor 1 1.87659
EGR1 early growth response 1 1.87592
MPO myeloperoxidase 1.85485
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.85397
CLU clusterin 1.85309
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.83877
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.82884
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.8222
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.81903
GSK3B glycogen synthase kinase 3 beta 1.81903
MBP myelin basic protein 1.81593
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.81484
BID BH3 interacting domain death agonist 1.80868
NUPR1 nuclear protein, transcriptional regulator, 1 1.80491
BIRC5 baculoviral IAP repeat containing 5 1.80284
IGF1 insulin-like growth factor 1 (somatomedin C) 1.78701
MMP9 matrix metallopeptidase 9 1.78682
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.78606
ALB albumin 1.7834
COL1A1 collagen, type I, alpha 1 1.77335
SOD1 superoxide dismutase 1, soluble 1.7714
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.77043
EGFR epidermal growth factor receptor 1.7623
NOS3 nitric oxide synthase 3 (endothelial cell) 1.7623
APP amyloid beta (A4) precursor protein 1.75162
CXCL10 chemokine (C-X-C motif) ligand 10 1.7418
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.73978
IL1A interleukin 1, alpha 1.73516
PRL prolactin 1.72467
TAGLN transgelin 1.72302
SGK1 serum/glucocorticoid regulated kinase 1 1.72116
F3 coagulation factor III (thromboplastin, tissue factor) 1.71748
CXCR4 chemokine (C-X-C motif) receptor 4 1.71748
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.71647
IL5 interleukin 5 1.70906
BTG2 BTG family, member 2 1.70823
ATF3 activating transcription factor 3 1.70823
G6PD glucose-6-phosphate dehydrogenase 1.7074
IGFBP5 insulin-like growth factor binding protein 5 1.70678
C3 complement component 3 1.70098
FASLG Fas ligand (TNF superfamily, member 6) 1.69576
BDNF brain-derived neurotrophic factor 1.69491
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.67311
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.67224
MAPK8 mitogen-activated protein kinase 8 1.67094
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.66339
IL2 interleukin 2 1.65665
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.65
CCL3 chemokine (C-C motif) ligand 3 1.64595
TGFB2 transforming growth factor, beta 2 1.64303
GADD45A growth arrest and DNA-damage-inducible, alpha 1.64168
PPARG peroxisome proliferator-activated receptor gamma 1.63608
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.63518
HSPA8 heat shock 70kDa protein 8 1.6325
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.62669
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.62669
PGD phosphogluconate dehydrogenase 1.62579
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 1.62106
MMP2 matrix metallopeptidase 2 1.61365
NPPA natriuretic peptide A 1.61271
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.60758
CALB1 calbindin 1, 28kDa 1.59264
DUSP1 dual specificity phosphatase 1 1.59218
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.59077
EPO erythropoietin 1.58184
THBS1 thrombospondin 1 1.57971
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.57806
REN renin 1.57712
NOS1 nitric oxide synthase 1 (neuronal) 1.57546
CCNG1 cyclin G1 1.56899
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.56068
KRT8 keratin 8, type II 1.55846
NPY neuropeptide Y 1.54815
MGP matrix Gla protein 1.5479
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.54693
UBE2C ubiquitin-conjugating enzyme E2C 1.54281
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.54184
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.53868
MAPK14 mitogen-activated protein kinase 14 1.53796
BAD BCL2-associated agonist of cell death 1.53012
IL12A interleukin 12A 1.52693
SELL selectin L 1.52642
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.52287
LCN2 lipocalin 2 1.52287
RGS4 regulator of G-protein signaling 4 1.52287
DBN1 drebrin 1 1.52187
GSTM1 glutathione S-transferase mu 1 1.52187
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.51531
TFRC transferrin receptor 1.51481
POMC proopiomelanocortin 1.5128
DNASE1 deoxyribonuclease I 1.5128
CCND1 cyclin D1 1.51004
CD44 CD44 molecule (Indian blood group) 1.50979
MMP3 matrix metallopeptidase 3 1.50448
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.50298
CXCL12 chemokine (C-X-C motif) ligand 12 1.49533
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.49356
CALR calreticulin 1.492
HSPB1 heat shock 27kDa protein 1 1.48736
GFAP glial fibrillary acidic protein 1.48659
NQO1 NAD(P)H dehydrogenase, quinone 1 1.48505
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.48325
POR P450 (cytochrome) oxidoreductase 1.48325
PKLR pyruvate kinase, liver and RBC 1.48222
GJB1 gap junction protein, beta 1, 32kDa 1.48222
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.4794
C10ORF10 chromosome 10 open reading frame 10 1.47787
BBC3 BCL2 binding component 3 1.4766
CYBA cytochrome b-245, alpha polypeptide 1.47452
JAK1 Janus kinase 1 1.47348
CFLAR CASP8 and FADD-like apoptosis regulator 1.45962
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.45803
RRM2 ribonucleotide reductase M2 1.4575
PDE4B phosphodiesterase 4B, cAMP-specific 1.44845
IL12B interleukin 12B 1.44817
NGF nerve growth factor (beta polypeptide) 1.44817
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.44572
GPX3 glutathione peroxidase 3 1.4449
EDNRB endothelin receptor type B 1.4449
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 1.44409
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.44355
CDKN2A cyclin-dependent kinase inhibitor 2A 1.44327
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.43892
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.43646
NOX4 NADPH oxidase 4 1.43482
H2AFX H2A histone family, member X 1.43374
GSR glutathione reductase 1.43266
CYCS cytochrome c, somatic 1.43239
NRP1 neuropilin 1 1.43239
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.43076
GFRA2 GDNF family receptor alpha 2 1.42777
CREB1 cAMP responsive element binding protein 1 1.42642
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.42401
VGF VGF nerve growth factor inducible 1.42238
CCL5 chemokine (C-C motif) ligand 5 1.4202
IGFBP1 insulin-like growth factor binding protein 1 1.41938
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.41721
MCL1 myeloid cell leukemia 1 1.41559
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.41229
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.41229
CTSL cathepsin L 1.4098
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.4098
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.40457
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.40316
GSK3A glycogen synthase kinase 3 alpha 1.40232
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 1.39757
S100A9 S100 calcium binding protein A9 1.39535
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.39338
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.3917
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.39086
TAC1 tachykinin, precursor 1 1.39086
EMP1 epithelial membrane protein 1 1.3878
FADS1 fatty acid desaturase 1 1.3878
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.38612
RAMP2 receptor (G protein-coupled) activity modifying protein 2 1.38355
EIF4E eukaryotic translation initiation factor 4E 1.38156
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.38128
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.37902
PPARA peroxisome proliferator-activated receptor alpha 1.37733
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.37676
RGS2 regulator of G-protein signaling 2 1.37676
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 1.37446
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.37246
TIMP3 TIMP metallopeptidase inhibitor 3 1.37246
PENK proenkephalin 1.37246
HAVCR1 hepatitis A virus cellular receptor 1 1.37217
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.37018
EGF epidermal growth factor 1.3699
GATA3 GATA binding protein 3 1.36933
IGFBP3 insulin-like growth factor binding protein 3 1.36735
CCNA2 cyclin A2 1.36706
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.36361
FGFR3 fibroblast growth factor receptor 3 1.36332
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.36133
LTF lactotransferrin 1.35734
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.34489
ITGB5 integrin, beta 5 1.34489
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.34489
SRXN1 sulfiredoxin 1 1.34459
VLDLR very low density lipoprotein receptor 1.34314
ANXA1 annexin A1 1.34256
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.34053
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 1.34053
CTGF connective tissue growth factor 1.33791
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 1.33761
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.33761
LCK LCK proto-oncogene, Src family tyrosine kinase 1.33287
PCNA proliferating cell nuclear antigen 1.33199
GDF15 growth differentiation factor 15 1.32993
PLAT plasminogen activator, tissue 1.32993
PTEN phosphatase and tensin homolog 1.32993
TEK TEK tyrosine kinase, endothelial 1.32905
GCLC glutamate-cysteine ligase, catalytic subunit 1.32876
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.32816
KLF4 Kruppel-like factor 4 (gut) 1.32667
GPX1 glutathione peroxidase 1 1.32577
MAP7 microtubule-associated protein 7 1.32547
CRYAB crystallin, alpha B 1.32015
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.32015
PSD3 pleckstrin and Sec7 domain containing 3 1.31956
VIM vimentin 1.31927
MMP13 matrix metallopeptidase 13 1.31837
XBP1 X-box binding protein 1 1.31446
HK1 hexokinase 1 1.31387
INA internexin neuronal intermediate filament protein, alpha 1.31357
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1.3085
THBS4 thrombospondin 4 1.30819
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.30666
FABP7 fatty acid binding protein 7, brain 1.30635
CCL11 chemokine (C-C motif) ligand 11 1.30574
LEP leptin 1.3036
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.30299
CPT1A carnitine palmitoyltransferase 1A (liver) 1.30087
CXCL2 chemokine (C-X-C motif) ligand 2 1.29996
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 1.29936
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.29657
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 1.29564
DDIT4 DNA-damage-inducible transcript 4 1.29348
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.29317
CASP12 caspase 12 (gene/pseudogene) 1.29317
CUBN cubilin (intrinsic factor-cobalamin receptor) 1.29287
ACE angiotensin I converting enzyme 1.29164
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 1.29133
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.28919
ACTA1 actin, alpha 1, skeletal muscle 1.28858
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 1.2861
KCNK1 potassium channel, two pore domain subfamily K, member 1 1.2861
PER1 period circadian clock 1 1.28518
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 1.28518
TAGLN3 transgelin 3 1.28395
DHFR dihydrofolate reductase 1.28333
AVP arginine vasopressin 1.28333
EGR2 early growth response 2 1.28088
HPCAL1 hippocalcin-like 1 1.28088
PRKCD protein kinase C, delta 1.2772
IL13 interleukin 13 1.27193
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 1.27101
LGALS3 lectin, galactoside-binding, soluble, 3 1.26917
CCL20 chemokine (C-C motif) ligand 20 1.267
ABHD4 abhydrolase domain containing 4 1.26607
ACSS2 acyl-CoA synthetase short-chain family member 2 1.26576
ANXA4 annexin A4 1.26545
PDIA4 protein disulfide isomerase family A, member 4 1.26545
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.26483
NFE2L2 nuclear factor, erythroid 2-like 2 1.26267
PDGFB platelet-derived growth factor beta polypeptide 1.26236
PRKCZ protein kinase C, zeta 1.26236
MGEA5 meningioma expressed antigen 5 (hyaluronidase) 1.26113
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.26021
CCNB1 cyclin B1 1.2599
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.25899
PRKCB protein kinase C, beta 1.25369
C1S complement component 1, s subcomponent 1.25276
RB1 retinoblastoma 1 1.25028
IGFBP4 insulin-like growth factor binding protein 4 1.24997
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.24935
PCDH7 protocadherin 7 1.24718
CDC25A cell division cycle 25A 1.24687
FOSL2 FOS-like antigen 2 1.24687
PLG plasminogen 1.24687
ADM adrenomedullin 1.24496
FN1 fibronectin 1 1.24433
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.2437
PLN phospholamban 1.24275
EFNB3 ephrin-B3 1.24275
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.23837
ACACA acetyl-CoA carboxylase alpha 1.23837
TGFBR1 transforming growth factor, beta receptor 1 1.23806
INHBE inhibin, beta E 1.23806
CRP C-reactive protein, pentraxin-related 1.2352
KLF10 Kruppel-like factor 10 1.23488
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.23424
IRF9 interferon regulatory factor 9 1.23392
S100B S100 calcium binding protein B 1.23201
VDAC1 voltage-dependent anion channel 1 1.23201
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.23201
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.23011
IRS1 insulin receptor substrate 1 1.2279
GAP43 growth associated protein 43 1.22632
IFITM1 interferon induced transmembrane protein 1 1.22534
IER5 immediate early response 5 1.22534
INS insulin 1.22404
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.2208
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 1.2208
ACO2 aconitase 2, mitochondrial 1.22048
TOP2A topoisomerase (DNA) II alpha 170kDa 1.21919
COL3A1 collagen, type III, alpha 1 1.21759
DHCR24 24-dehydrocholesterol reductase 1.21501
APOE apolipoprotein E 1.21468
BAK1 BCL2-antagonist/killer 1 1.21173
GJA1 gap junction protein, alpha 1, 43kDa 1.21173
STAT1 signal transducer and activator of transcription 1, 91kDa 1.21173
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 1.20978
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 1.20946
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 1.20751
ENC1 ectodermal-neural cortex 1 (with BTB domain) 1.20687
SDF2L1 stromal cell-derived factor 2-like 1 1.2046
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 1.20394
CNR1 cannabinoid receptor 1 (brain) 1.20361
EGFL6 EGF-like-domain, multiple 6 1.20196
ARHGAP9 Rho GTPase activating protein 9 1.20163
CKB creatine kinase, brain 1.2013
HDAC1 histone deacetylase 1 1.2013
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.2013
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 1.20064
ELOVL6 ELOVL fatty acid elongase 6 1.19868
FOXO1 forkhead box O1 1.19607
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.19509
E2F1 E2F transcription factor 1 1.19412
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 1.19279
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 1.19279
ODC1 ornithine decarboxylase 1 1.18915
IL3 interleukin 3 1.18915
IL23A interleukin 23, alpha subunit p19 1.18915
DUSP10 dual specificity phosphatase 10 1.18882
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.18882
GSTM3 glutathione S-transferase mu 3 (brain) 1.18849
CHEK1 checkpoint kinase 1 1.18849
MGMT O-6-methylguanine-DNA methyltransferase 1.18849
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 1.18816
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) 1.18783
ATF4 activating transcription factor 4 1.18652
FGA fibrinogen alpha chain 1.18554
NAMPT nicotinamide phosphoribosyltransferase 1.18554
ACTB actin, beta 1.18456
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.18326
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 1.18193
TNNI3 troponin I type 3 (cardiac) 1.18159
RUNX1 runt-related transcription factor 1 1.18126
TF transferrin 1.17926
EEF2 eukaryotic translation elongation factor 2 1.17827
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 1.17761
MUC1 mucin 1, cell surface associated 1.17761
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.17629
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.17563
TIMP2 TIMP metallopeptidase inhibitor 2 1.17366
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.17366
INHBA inhibin, beta A 1.17333
F2R coagulation factor II (thrombin) receptor 1.17067
PRLR prolactin receptor 1.17067
FGFR1 fibroblast growth factor receptor 1 1.17067
ATF5 activating transcription factor 5 1.17067
PRPH peripherin 1.17
ADAM19 ADAM metallopeptidase domain 19 1.17
TJP3 tight junction protein 3 1.17
CTSD cathepsin D 1.17
SQSTM1 sequestosome 1 1.16833
FOSL1 FOS-like antigen 1 1.16833
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 1.16833
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 1.167
SLIT1 slit homolog 1 (Drosophila) 1.16666
OAT ornithine aminotransferase 1.16335
ALAD aminolevulinate dehydratase 1.16104
VCAN versican 1.16001
WNT5A wingless-type MMTV integration site family, member 5A 1.16001
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.15865
GATA5 GATA binding protein 5 1.15661
IL1R1 interleukin 1 receptor, type I 1.15627
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 1.15324
SYP synaptophysin 1.15324
S100A1 S100 calcium binding protein A1 1.15324
F2 coagulation factor II (thrombin) 1.15089
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.14989
RND3 Rho family GTPase 3 1.14989
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 1.14989
PRNP prion protein 1.14954
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.14954
H1FX H1 histone family, member X 1.14781
FKBP1B FK506 binding protein 1B, 12.6 kDa 1.14781
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.14781
EDNRA endothelin receptor type A 1.14713
PROS1 protein S (alpha) 1.14644
SPTBN1 spectrin, beta, non-erythrocytic 1 1.14644
ACVR1B activin A receptor, type IB 1.1461
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.14507
RPS6 ribosomal protein S6 1.14234
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.1403
COL18A1 collagen, type XVIII, alpha 1 1.13997
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.13895
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.13793
HSPA9 heat shock 70kDa protein 9 (mortalin) 1.13793
CD52 CD52 molecule 1.13724
RNF152 ring finger protein 152 1.13655
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.13381
ARG1 arginase 1 1.13347
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 1.13347
HDC histidine decarboxylase 1.13347
NEFM neurofilament, medium polypeptide 1.13347
PCOLCE procollagen C-endopeptidase enhancer 1.13245
TRIB2 tribbles pseudokinase 2 1.13211
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 1.12737
STMN1 stathmin 1 1.12703
S100A8 S100 calcium binding protein A8 1.12703
CLCN4 chloride channel, voltage-sensitive 4 1.12703
GAL galanin/GMAP prepropeptide 1.12703
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.12495
S100A10 S100 calcium binding protein A10 1.12391
SMAD7 SMAD family member 7 1.12391
CARTPT CART prepropeptide 1.12254
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.12254
GPX2 glutathione peroxidase 2 1.12254
PTK2 protein tyrosine kinase 2 1.12048
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1.11843
NTF3 neurotrophin 3 1.11809
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 1.11809
RXRG retinoid X receptor, gamma 1.11809
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1.11809
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 1.11775
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.11775
CD4 CD4 molecule 1.11775
IL16 interleukin 16 1.11775
KNG1 kininogen 1 1.11639
MAP2K1 mitogen-activated protein kinase kinase 1 1.11639
CYBB cytochrome b-245, beta polypeptide 1.11639
MME membrane metallo-endopeptidase 1.11501
CAPN2 calpain 2, (m/II) large subunit 1.11501
CHUK conserved helix-loop-helix ubiquitous kinase 1.11431
ANXA5 annexin A5 1.11431
DUSP8 dual specificity phosphatase 8 1.1129
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 1.1129
MXI1 MAX interactor 1, dimerization protein 1.1129
GJB2 gap junction protein, beta 2, 26kDa 1.11186
CDK1 cyclin-dependent kinase 1 1.10977
BNC2 basonuclin 2 1.10942
GPNMB glycoprotein (transmembrane) nmb 1.10907
MAP2K2 mitogen-activated protein kinase kinase 2 1.10803
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 1.10803
JUNB jun B proto-oncogene 1.10699
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.10596
PTK2B protein tyrosine kinase 2 beta 1.10596
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.10596
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.10596
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 1.10388
HPN hepsin 1.10388
CDA cytidine deaminase 1.10388
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 1.10353
IFI30 interferon, gamma-inducible protein 30 1.10353
SOCS2 suppressor of cytokine signaling 2 1.10317
COL4A1 collagen, type IV, alpha 1 1.10317
NR1D1 nuclear receptor subfamily 1, group D, member 1 1.10317
CYR61 cysteine-rich, angiogenic inducer, 61 1.10175
SYNPO2 synaptopodin 2 1.1014
CLDN1 claudin 1 1.10033
DLAT dihydrolipoamide S-acetyltransferase 1.09927
SERINC3 serine incorporator 3 1.09927
TG thyroglobulin 1.09927
HRK harakiri, BCL2 interacting protein 1.09892
DAP death-associated protein 1.09892
PGM1 phosphoglucomutase 1 1.09892
CCND3 cyclin D3 1.09786
PER2 period circadian clock 2 1.09751
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.09751
GRN granulin 1.09716
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9 1.09576
RBPMS RNA binding protein with multiple splicing 1.09471
EMP3 epithelial membrane protein 3 1.09471
C4B complement component 4B (Chido blood group) 1.09471
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 1.09471
GLDC glycine dehydrogenase (decarboxylating) 1.09471
LSP1 lymphocyte-specific protein 1 1.09471
CDC42 cell division cycle 42 1.09436
MARCKS myristoylated alanine-rich protein kinase C substrate 1.09436
ECH1 enoyl CoA hydratase 1, peroxisomal 1.09436
CSF1 colony stimulating factor 1 (macrophage) 1.09436
HMHA1 histocompatibility (minor) HA-1 1.09332
USP36 ubiquitin specific peptidase 36 1.09332
ECE2 endothelin converting enzyme 2 1.09297
MT3 metallothionein 3 1.0919
PDYN prodynorphin 1.09154
CD38 CD38 molecule 1.09154
SCNN1A sodium channel, non voltage gated 1 alpha subunit 1.09154
ASPA aspartoacylase 1.09047
DPYSL2 dihydropyrimidinase-like 2 1.09047
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 1.09011
GRPEL1 GrpE-like 1, mitochondrial (E. coli) 1.09011
INSIG1 insulin induced gene 1 1.08975
DPP4 dipeptidyl-peptidase 4 1.08904
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.08904
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 1.08868
MAP3K5 mitogen-activated protein kinase kinase kinase 5 1.08868
SLCO2A1 solute carrier organic anion transporter family, member 2A1 1.08619
DCXR dicarbonyl/L-xylulose reductase 1.08584
ISYNA1 inositol-3-phosphate synthase 1 1.08584
CD8A CD8a molecule 1.08584
PTN pleiotrophin 1.08584
FAM65B family with sequence similarity 65, member B 1.08513
MAOA monoamine oxidase A 1.08407
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.08301
RAMP1 receptor (G protein-coupled) activity modifying protein 1 1.08161
LY6E lymphocyte antigen 6 complex, locus E 1.08161
AREG amphiregulin 1.07804
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.07804
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 1.07804
EPHB3 EPH receptor B3 1.07768
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 1.07732
TMSB4X thymosin beta 4, X-linked 1.07732
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.07589
CCNG2 cyclin G2 1.07518
UNG uracil-DNA glycosylase 1.07518
TNC tenascin C 1.07518
MUCL1 mucin-like 1 1.07376
GRM1 glutamate receptor, metabotropic 1 1.0734
LYZ lysozyme 1.0734
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 1.07305
GHR growth hormone receptor 1.07234
ENO1 enolase 1, (alpha) 1.07057
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.06987
PA2G4 proliferation-associated 2G4, 38kDa 1.06917
CTSH cathepsin H 1.06917
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 1.06917
S100A4 S100 calcium binding protein A4 1.06734
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 1.06552
BTG3 BTG family, member 3 1.06515
SMAD2 SMAD family member 2 1.06479
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.06479
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 1.06333
SP1 Sp1 transcription factor 1.06297
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.06188
GSN gelsolin 1.06188
BHLHE40 basic helix-loop-helix family, member e40 1.06188
CREM cAMP responsive element modulator 1.06188
FASN fatty acid synthase 1.06152
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 1.06116
LPL lipoprotein lipase 1.06008
HSPA1A heat shock 70kDa protein 1A 1.06008
TSC22D3 TSC22 domain family, member 3 1.05936
ACHE acetylcholinesterase (Yt blood group) 1.05793
ATM ATM serine/threonine kinase 1.05757
LMCD1 LIM and cysteine-rich domains 1 1.05757
AHCY adenosylhomocysteinase 1.05757
EEF1G eukaryotic translation elongation factor 1 gamma 1.05721
NINJ1 ninjurin 1 1.05721
GUCY1B3 guanylate cyclase 1, soluble, beta 3 1.05721
FBLN1 fibulin 1 1.05721
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 1.05685
ALDOA aldolase A, fructose-bisphosphate 1.05685
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) 1.05648
BEGAIN brain-enriched guanylate kinase-associated 1.05573
SFRP2 secreted frizzled-related protein 2 1.05349
CLIC4 chloride intracellular channel 4 1.05349
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 1.05163
IFRD1 interferon-related developmental regulator 1 1.05163
ARG2 arginase 2 1.05163
IGF1R insulin-like growth factor 1 receptor 1.05015
PTPRA protein tyrosine phosphatase, receptor type, A 1.04978
UBE2I ubiquitin-conjugating enzyme E2I 1.04941
LGALS1 lectin, galactoside-binding, soluble, 1 1.04941
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 1.04941
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 1.04941
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 1.04941
CORO1C coronin, actin binding protein, 1C 1.04941
MSMO1 methylsterol monooxygenase 1 1.04904
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.04574
MALAT1 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding) 1.04574
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 1.04574
ANGPT1 angiopoietin 1 1.04574
PTPRC protein tyrosine phosphatase, receptor type, C 1.04538
PLTP phospholipid transfer protein 1.04538
THRA thyroid hormone receptor, alpha 1.04427
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.04427
PCSK2 proprotein convertase subtilisin/kexin type 2 1.04314
KLK6 kallikrein-related peptidase 6 1.04276
SEPT4 septin 4 1.04276
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.04201
GPER1 G protein-coupled estrogen receptor 1 1.04163
TMSB10 thymosin beta 10 1.04163
GEM GTP binding protein overexpressed in skeletal muscle 1.04163
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.04163
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 1.04163
A2M alpha-2-macroglobulin 1.04163
HSPE1 heat shock 10kDa protein 1 1.04163
MAPK9 mitogen-activated protein kinase 9 1.04088
COL1A2 collagen, type I, alpha 2 1.03976
GAMT guanidinoacetate N-methyltransferase 1.03789
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 1.03678
FNDC4 fibronectin type III domain containing 4 1.03678
FMO1 flavin containing monooxygenase 1 1.03678
IDI1 isopentenyl-diphosphate delta isomerase 1 1.03678
HCRT hypocretin (orexin) neuropeptide precursor 1.03678
PRTN3 proteinase 3 1.03641
PPAN peter pan homolog (Drosophila) 1.03641
GPRC5C G protein-coupled receptor, class C, group 5, member C 1.03641
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 1.03604
AXL AXL receptor tyrosine kinase 1.03456
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.03456
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 1.03456
GSTA2 glutathione S-transferase alpha 2 1.03419
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 1.03419
KRT17 keratin 17, type I 1.03419
PTMA prothymosin, alpha 1.03419
AQP1 aquaporin 1 (Colton blood group) 1.03197
ALAS1 5'-aminolevulinate synthase 1 1.03197
S1PR1 sphingosine-1-phosphate receptor 1 1.03084
BCL3 B-cell CLL/lymphoma 3 1.03046
GJA5 gap junction protein, alpha 5, 40kDa 1.03046
CIDEB cell death-inducing DFFA-like effector b 1.03046
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 1.03046
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 1.03009
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 1.03009
PCCB propionyl CoA carboxylase, beta polypeptide 1.03009
FKBP5 FK506 binding protein 5 1.02971
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 1.02971
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide 1.02971
PLAU plasminogen activator, urokinase 1.02933
DRD2 dopamine receptor D2 1.02783
TXNRD1 thioredoxin reductase 1 1.02783
GPR20 G protein-coupled receptor 20 1.02746
COL6A1 collagen, type VI, alpha 1 1.02708
AK4 adenylate kinase 4 1.02708
PARK7 parkinson protein 7 1.02708
GPM6B glycoprotein M6B 1.0241
SCG2 secretogranin II 1.0241
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 1.02373
SORD sorbitol dehydrogenase 1.02373
VASN vasorin 1.02373
LYN LYN proto-oncogene, Src family tyrosine kinase 1.02373
MFN2 mitofusin 2 1.02373
ATP7A ATPase, Cu++ transporting, alpha polypeptide 1.02373
ACACB acetyl-CoA carboxylase beta 1.02336
TYMS thymidylate synthetase 1.02262
CSF1R colony stimulating factor 1 receptor 1.02003
PHLDA2 pleckstrin homology-like domain, family A, member 2 1.02003
PHLDA3 pleckstrin homology-like domain, family A, member 3 1.02003
AQP2 aquaporin 2 (collecting duct) 1.01852
PDK4 pyruvate dehydrogenase kinase, isozyme 4 1.01814
GRB7 growth factor receptor-bound protein 7 1.01776
PRDX2 peroxiredoxin 2 1.01776
BIK BCL2-interacting killer (apoptosis-inducing) 1.01663
KLF6 Kruppel-like factor 6 1.01587
TJP1 tight junction protein 1 1.01549
GLRB glycine receptor, beta 1.01512
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.01361
PDGFA platelet-derived growth factor alpha polypeptide 1.01361
ECI1 enoyl-CoA delta isomerase 1 1.01324
KDR kinase insert domain receptor 1.01249
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 1.01212
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 1.01212
CCL4 chemokine (C-C motif) ligand 4 1.01099