Vasculitis Gene Set

Dataset DISEASES Experimental Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A vascular disease that is characterized by inflammation of the blood vessels. (Human Disease Ontology, DOID_865)
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Genes

173 genes associated with the disease Vasculitis in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 1.975
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 1.972
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 1.972
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.972
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.972
HLA-B major histocompatibility complex, class I, B 1.972
BTNL2 butyrophilin-like 2 1.957
TSBP1 testis expressed basic protein 1 1.957
HLA-DRA major histocompatibility complex, class II, DR alpha 1.957
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 1.938
IL10 interleukin 10 1.938
IL19 interleukin 19 1.938
IL20 interleukin 20 1.938
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 1.938
PSORS1C1 psoriasis susceptibility 1 candidate 1 1.854
CCHCR1 coiled-coil alpha-helical rod protein 1 1.854
PSORS1C2 psoriasis susceptibility 1 candidate 2 1.854
C6ORF15 chromosome 6 open reading frame 15 1.854
POU5F1 POU class 5 homeobox 1 1.854
TCF19 transcription factor 19 1.854
MUC22 mucin 22 1.854
LY6G5C lymphocyte antigen 6 complex, locus G5C 1.696
MPIG6B megakaryocyte and platelet inhibitory receptor G6b 1.696
CSNK2B casein kinase 2, beta polypeptide 1.696
LY6G6C lymphocyte antigen 6 complex, locus G6C 1.696
LY6G6D lymphocyte antigen 6 complex, locus G6D 1.696
LY6G6F lymphocyte antigen 6 complex, locus G6F 1.696
ABHD16A abhydrolase domain containing 16A 1.696
GPANK1 G patch domain and ankyrin repeats 1 1.696
LY6G5B lymphocyte antigen 6 complex, locus G5B 1.696
BAG6 BCL2-associated athanogene 6 1.695
APOM apolipoprotein M 1.695
C6ORF47 chromosome 6 open reading frame 47 1.695
CLIC1 chloride intracellular channel 1 1.695
DDAH2 dimethylarginine dimethylaminohydrolase 2 1.695
PRRC2A proline-rich coiled-coil 2A 1.694
AIF1 allograft inflammatory factor 1 1.694
LST1 leukocyte specific transcript 1 1.692
NCR3 natural cytotoxicity triggering receptor 3 1.692
LTB lymphotoxin beta (TNF superfamily, member 3) 1.689
LTA lymphotoxin alpha 1.686
TNF tumor necrosis factor 1.686
MSH5 mutS homolog 5 1.682
SAPCD1 suppressor APC domain containing 1 1.676
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 1.656
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 1.656
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 1.656
VWA7 von Willebrand factor A domain containing 7 1.647
IL12A interleukin 12A 1.64
VARS1 valyl-tRNA synthetase 1 1.634
CCR1 chemokine (C-C motif) receptor 1 1.625
XCR1 chemokine (C motif) receptor 1 1.625
CCR3 chemokine (C-C motif) receptor 3 1.625
PTK2B protein tyrosine kinase 2 beta 1.593
TRIM35 tripartite motif containing 35 1.593
STMN4 stathmin-like 4 1.593
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 1.579
HSPA6 heat shock 70kDa protein 6 (HSP70B') 1.579
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.579
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.579
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 1.57
EGFL8 EGF-like-domain, multiple 8 1.57
NOTCH4 notch 4 1.57
GPSM3 G-protein signaling modulator 3 1.57
PRRT1 proline-rich transmembrane protein 1 1.57
AGER advanced glycosylation end product-specific receptor 1.57
PBX2 pre-B-cell leukemia homeobox 2 1.57
ATF6B activating transcription factor 6 beta 1.57
PPT2 palmitoyl-protein thioesterase 2 1.57
FKBPL FK506 binding protein like 1.57
TNXB tenascin XB 1.57
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 1.57
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.538
IL23R interleukin 23 receptor 1.518
IL12RB2 interleukin 12 receptor, beta 2 1.518
C1ORF141 chromosome 1 open reading frame 141 1.518
HLA-DOB major histocompatibility complex, class II, DO beta 1.501
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 1.501
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 1.501
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 1.501
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 1.501
TRIM26 tripartite motif containing 26 1.493
TRIM15 tripartite motif containing 15 1.493
TRIM40 tripartite motif containing 40 1.493
TRIM10 tripartite motif containing 10 1.493
TRIM31 tripartite motif containing 31 1.493
HSPA1A heat shock 70kDa protein 1A 1.455
HSPA1L heat shock 70kDa protein 1-like 1.455
HSPA1B heat shock 70kDa protein 1B 1.455
CAST calpastatin 1.451
ERAP1 endoplasmic reticulum aminopeptidase 1 1.451
ERAP2 endoplasmic reticulum aminopeptidase 2 1.451
SCHIP1 schwannomin interacting protein 1 1.422
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 1.41
RNF39 ring finger protein 39 1.41
ACOXL acyl-CoA oxidase-like 1.405
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.405
LPA lipoprotein, Lp(a) 1.395
PLG plasminogen 1.395
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 1.387
BRWD1 bromodomain and WD repeat domain containing 1 1.387
STAT4 signal transducer and activator of transcription 4 1.374
MYO1B myosin IB 1.374
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 1.32
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 1.32
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 1.32
RPS9 ribosomal protein S9 1.32
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 1.32
TSEN34 TSEN34 tRNA splicing endonuclease subunit 1.32
EIF2S3B eukaryotic translation initiation factor 2 subunit gamma B 1.302
KLRC2 killer cell lectin-like receptor subfamily C, member 2 1.302
KLRD1 killer cell lectin-like receptor subfamily D, member 1 1.302
KLRC1 killer cell lectin-like receptor subfamily C, member 1 1.302
KLRC3 killer cell lectin-like receptor subfamily C, member 3 1.302
KLRC4 killer cell lectin-like receptor subfamily C, member 4 1.302
KLRK1 killer cell lectin-like receptor subfamily K, member 1 1.302
MCCD1 mitochondrial coiled-coil domain 1 1.264
MTERF1 mitochondrial transcription termination factor 1 1.216
AKAP9 A kinase (PRKA) anchor protein 9 1.216
SLC44A4 solute carrier family 44, member 4 1.201
NEU1 sialidase 1 (lysosomal sialidase) 1.201
TFCP2L1 transcription factor CP2-like 1 1.19
CLASP1 cytoplasmic linker associated protein 1 1.19
MAMSTR MEF2 activating motif and SAP domain containing transcriptional regulator 1.188
RPL18 ribosomal protein L18 1.188
IZUMO1 izumo sperm-egg fusion 1 1.188
SACK1E scaffolding CK1 anchoring protein E 1.188
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 1.188
SPACA4 sperm acrosome associated 4 1.188
NTN5 netrin 5 1.188
CA11 carbonic anhydrase XI 1.188
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 1.188
SPHK2 sphingosine kinase 2 1.188
DBP D site of albumin promoter (albumin D-box) binding protein 1.188
RASIP1 Ras interacting protein 1 1.188
FGF21 fibroblast growth factor 21 1.188
FUT2 fucosyltransferase 2 (secretor status included) 1.188
MBOAT7 membrane bound O-acyltransferase domain containing 7 1.182
TMC4 transmembrane channel-like 4 1.182
CNOT3 CCR4-NOT transcription complex, subunit 3 1.182
PRPF31 pre-mRNA processing factor 31 1.182
LENG1 leukocyte receptor cluster (LRC) member 1 1.182
PDLIM4 PDZ and LIM domain 4 1.182
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 1.182
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 1.182
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 1.182
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) 1.182
PNP purine nucleoside phosphorylase 1.143
PIP4P1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 1.143
PARP2 poly (ADP-ribose) polymerase 2 1.143
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 1.143
RNASE10 ribonuclease, RNase A family, 10 (non-active) 1.143
OSGEP O-sialoglycoprotein endopeptidase 1.143
KLHL33 kelch-like family member 33 1.143
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.143
TEP1 telomerase-associated protein 1 1.143
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 1.074
IL6 interleukin 6 1.023
STEAP1B STEAP family member 1B 1.023
TOMM7 translocase of outer mitochondrial membrane 7 homolog (yeast) 1.023
RBM28 RNA binding motif protein 28 0.923
PRRT4 proline-rich transmembrane protein 4 0.923
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 0.923
LEP leptin 0.923
WDR36 WD repeat domain 36 0.73
TSLP thymic stromal lymphopoietin 0.73
HLA-C major histocompatibility complex, class I, C 0.722
CNTN5 contactin 5 0.631
OTOGL otogelin-like 0.588
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.588
DUSP22 dual specificity phosphatase 22 0.581
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 0.548
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 0.548