Vasculitis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A vascular disease that is characterized by inflammation of the blood vessels. (Human Disease Ontology, DOID_865)
External Link https://www.disgenet.org/browser/0/1/0/C0042384
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Genes

282 genes associated with the disease Vasculitis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ACE angiotensin I converting enzyme
ACR acrosin
ADA adenosine deaminase
ADA2 adenosine deaminase 2
ADIPOR1 adiponectin receptor 1
ADIPOR2 adiponectin receptor 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHR aryl hydrocarbon receptor
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALB albumin
ANGPT2 angiopoietin 2
ANPEP alanyl (membrane) aminopeptidase
APOA2 apolipoprotein A-II
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa
ATN1 atrophin 1
BCL2 B-cell CLL/lymphoma 2
BLK BLK proto-oncogene, Src family tyrosine kinase
BPI bactericidal/permeability-increasing protein
BTG3 BTG family, member 3
C1QBP complement component 1, q subcomponent binding protein
C1QTNF1 C1q and tumor necrosis factor related protein 1
C4A complement component 4A (Rodgers blood group)
C5 complement component 5
C5AR1 complement component 5a receptor 1
CALR calreticulin
CAPS calcyphosine
CASP10 caspase 10, apoptosis-related cysteine peptidase
CAST calpastatin
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCL2 chemokine (C-C motif) ligand 2
CCL26 chemokine (C-C motif) ligand 26
CCL3L1 chemokine (C-C motif) ligand 3-like 1
CCL5 chemokine (C-C motif) ligand 5
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD163 CD163 molecule
CD177 CD177 molecule
CD19 CD19 molecule
CD1D CD1d molecule
CD1E CD1e molecule
CD22 CD22 molecule
CD226 CD226 molecule
CD244 CD244 molecule, natural killer cell receptor 2B4
CD274 CD274 molecule
CD28 CD28 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD79A CD79a molecule, immunoglobulin-associated alpha
CD81 CD81 molecule
CD83 CD83 molecule
CFH complement factor H
CFI complement factor I
CIITA class II, major histocompatibility complex, transactivator
CLEC6A C-type lectin domain family 6, member A
CLEC7A C-type lectin domain family 7, member A
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CP ceruloplasmin (ferroxidase)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRP C-reactive protein, pentraxin-related
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CSK c-src tyrosine kinase
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
CXCR3 chemokine (C-X-C motif) receptor 3
CYCS cytochrome c, somatic
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DEFB104A defensin, beta 104A
DEFB104B defensin, beta 104B
DEFB4A defensin, beta 4A
DEFB4B defensin, beta 4B
EGF epidermal growth factor
ELANE elastase, neutrophil expressed
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ENO1 enolase 1, (alpha)
EPHB1 EPH receptor B1
ERAP1 endoplasmic reticulum aminopeptidase 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EXT1 exostosin glycosyltransferase 1
F5 coagulation factor V (proaccelerin, labile factor)
F8 coagulation factor VIII, procoagulant component
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBLIM1 filamin binding LIM protein 1
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FGF23 fibroblast growth factor 23
FLNB filamin B, beta
FN1 fibronectin 1
GAS6 growth arrest-specific 6
GCA grancalcin, EF-hand calcium binding protein
GEMIN2 gem (nuclear organelle) associated protein 2
GOPC golgi-associated PDZ and coiled-coil motif containing
GRAP2 GRB2-related adaptor protein 2
GYPA glycophorin A (MNS blood group)
HAMP hepcidin antimicrobial peptide
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HMGB1 high mobility group box 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
ICAM1 intercellular adhesion molecule 1
ICOS inducible T-cell co-stimulator
IFIH1 interferon induced with helicase C domain 1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFNG interferon, gamma
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL17A interleukin 17A
IL17RA interleukin 17 receptor A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL21 interleukin 21
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IL26 interleukin 26
IL2RA interleukin 2 receptor, alpha
IL33 interleukin 33
IL5 interleukin 5
IL6 interleukin 6
IRF5 interferon regulatory factor 5
ISG15 ISG15 ubiquitin-like modifier
ISG20 interferon stimulated exonuclease gene 20kDa
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KLRC4 killer cell lectin-like receptor subfamily C, member 4
KRT20 keratin 20, type I
LAMC2 laminin, gamma 2
LAMP2 lysosomal-associated membrane protein 2
LAMP3 lysosomal-associated membrane protein 3
LEP leptin
LEPR leptin receptor
LMX1B LIM homeobox transcription factor 1, beta
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LOC102724971 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LPAR1 lysophosphatidic acid receptor 1
LSAMP limbic system-associated membrane protein
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK8 mitogen-activated protein kinase 8
MBL2 mannose-binding lectin (protein C) 2, soluble
MEFV Mediterranean fever
MICA MHC class I polypeptide-related sequence A
MLX MLX, MAX dimerization protein
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MOCOS molybdenum cofactor sulfurase
MPO myeloperoxidase
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MUC13 mucin 13, cell surface associated
MVK mevalonate kinase
MYD88 myeloid differentiation primary response 88
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NGF nerve growth factor (beta polypeptide)
NLRP3 NLR family, pyrin domain containing 3
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH4 notch 4
NT5E 5'-nucleotidase, ecto (CD73)
NXF1 nuclear RNA export factor 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
P4HB prolyl 4-hydroxylase, beta polypeptide
PADI4 peptidyl arginine deiminase, type IV
PAEP progestagen-associated endometrial protein
PALD1 phosphatase domain containing, paladin 1
PALLD palladin, cytoskeletal associated protein
PDCD1 programmed cell death 1
PLA2G1B phospholipase A2, group IB (pancreas)
PLAT plasminogen activator, tissue
PLB1 phospholipase B1
PLG plasminogen
PMP22 peripheral myelin protein 22
PNN pinin, desmosome associated protein
PODXL podocalyxin-like
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
POMC proopiomelanocortin
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRTN3 proteinase 3
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTX3 pentraxin 3, long
PXDN peroxidasin
PYCARD PYD and CARD domain containing
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RBM45 RNA binding motif protein 45
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPL17 ribosomal protein L17
RPL17-C18ORF32 RPL17-C18orf32 readthrough
RPL31 ribosomal protein L31
RPL9 ribosomal protein L9
RPS3A ribosomal protein S3A
RTEL1 regulator of telomere elongation helicase 1
RXRB retinoid X receptor, beta
S100A12 S100 calcium binding protein A12
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SAMHD1 SAM domain and HD domain 1
SCAF11 SR-related CTD-associated factor 11
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN11A sodium channel, voltage gated, type XI alpha subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SCP2 sterol carrier protein 2
SEC14L2 SEC14-like 2 (S. cerevisiae)
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SH2D1A SH2 domain containing 1A
SH3BP2 SH3-domain binding protein 2
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC26A5 solute carrier family 26 (anion exchanger), member 5
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMN1 survival of motor neuron 1, telomeric
SMN2 survival of motor neuron 2, centromeric
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPATA2 spermatogenesis associated 2
STAT4 signal transducer and activator of transcription 4
STING1 stimulator of interferon response cGAMP interactor 1
STS steroid sulfatase (microsomal), isozyme S
SYK spleen tyrosine kinase
TADA2A transcriptional adaptor 2A
TGFB1 transforming growth factor, beta 1
TIMP4 TIMP metallopeptidase inhibitor 4
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR7 toll-like receptor 7
TLR9 toll-like receptor 9
TNC tenascin C
TNF tumor necrosis factor
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNIP1 TNFAIP3 interacting protein 1
TPMT thiopurine S-methyltransferase
TREM1 triggering receptor expressed on myeloid cells 1
TSLP thymic stromal lymphopoietin
TUBA1C tubulin, alpha 1c
TYK2 tyrosine kinase 2
UBAC2 UBA domain containing 2
USO1 USO1 vesicle transport factor
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
VWF von Willebrand factor
WAS Wiskott-Aldrich syndrome
WDR11 WD repeat domain 11
WIPF1 WAS/WASL interacting protein family, member 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZEB2 zinc finger E-box binding homeobox 2