| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/151194 |
| Similar Terms | |
| Downloads & Tools |
199 proteins with high or low expression in Vatalanib relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| THAP9 | THAP domain containing 9 | 1.31 |
| DOCK11 | dedicator of cytokinesis 11 | 1.25 |
| LRRC46 | leucine rich repeat containing 46 | 1.24 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 1.23 |
| HIPK1 | homeodomain interacting protein kinase 1 | 1.2 |
| MT1X | metallothionein 1X | 0.94 |
| E2F8 | E2F transcription factor 8 | 0.7 |
| KMT2B | lysine (K)-specific methyltransferase 2B | 0.68 |
| DIPK1B | divergent protein kinase domain 1B | 0.67 |
| ATXN7L3 | ataxin 7-like 3 | 0.67 |
| FMNL3 | formin-like 3 | 0.63 |
| HPD | 4-hydroxyphenylpyruvate dioxygenase | 0.62 |
| MT1E | metallothionein 1E | 0.61 |
| MCRIP1 | MAPK regulated corepressor interacting protein 1 | 0.57 |
| NF1 | neurofibromin 1 | 0.56 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.53 |
| MGLL | monoglyceride lipase | 0.5 |
| YBX3 | Y box binding protein 3 | 0.5 |
| AHR | aryl hydrocarbon receptor | 0.48 |
| FAM110C | family with sequence similarity 110, member C | 0.48 |
| IL10RB | interleukin 10 receptor, beta | 0.47 |
| GPATCH3 | G patch domain containing 3 | 0.46 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.46 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 | 0.45 |
| CAPN6 | calpain 6 | 0.44 |
| ZHX3 | zinc fingers and homeoboxes 3 | 0.42 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.39 |
| LYSMD1 | LysM, putative peptidoglycan-binding, domain containing 1 | 0.39 |
| NMU | neuromedin U | 0.38 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.38 |
| PUS10 | pseudouridylate synthase 10 | 0.37 |
| TYSND1 | trypsin domain containing 1 | 0.37 |
| ZNF552 | zinc finger protein 552 | 0.36 |
| CEP89 | centrosomal protein 89kDa | 0.35 |
| DNLZ | DNL-type zinc finger | 0.35 |
| MT2A | metallothionein 2A | 0.35 |
| HSP90AB3P | heat shock protein 90kDa alpha (cytosolic), class B member 3, pseudogene | 0.35 |
| ANKRD26 | ankyrin repeat domain 26 | 0.35 |
| DEDD | death effector domain containing | 0.35 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.34 |
| GXYLT1 | glucoside xylosyltransferase 1 | 0.34 |
| CASKIN1 | CASK interacting protein 1 | 0.34 |
| PAQR4 | progestin and adipoQ receptor family member IV | 0.34 |
| GALNT13 | polypeptide N-acetylgalactosaminyltransferase 13 | 0.33 |
| ENTPD2 | ectonucleoside triphosphate diphosphohydrolase 2 | 0.33 |
| ACOX1 | acyl-CoA oxidase 1, palmitoyl | 0.33 |
| ANKLE1 | ankyrin repeat and LEM domain containing 1 | 0.33 |
| MCEE | methylmalonyl CoA epimerase | 0.33 |
| KLHL25 | kelch-like family member 25 | 0.32 |
| ZC3H14 | zinc finger CCCH-type containing 14 | 0.32 |
| NAAA | N-acylethanolamine acid amidase | 0.32 |
| INO80B | INO80 complex subunit B | 0.32 |
| LMBR1 | limb development membrane protein 1 | 0.31 |
| ZRANB1 | zinc finger, RAN-binding domain containing 1 | 0.31 |
| NDUFB8 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa | 0.31 |
| NRP1 | neuropilin 1 | 0.31 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 | 0.31 |
| TRAK2 | trafficking protein, kinesin binding 2 | 0.31 |
| DSTYK | dual serine/threonine and tyrosine protein kinase | 0.3 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.3 |
| PLAU | plasminogen activator, urokinase | 0.3 |
| BFAR | bifunctional apoptosis regulator | 0.29 |
| SSR4 | signal sequence receptor, delta | 0.29 |
| MRPL43 | mitochondrial ribosomal protein L43 | 0.29 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.29 |
| FUNDC1 | FUN14 domain containing 1 | 0.29 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.29 |
| SLC49A4 | solute carrier family 49 member 4 | 0.29 |
| ZNF655 | zinc finger protein 655 | 0.29 |
| ALG10B | ALG10B, alpha-1,2-glucosyltransferase | 0.28 |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa | 0.28 |
| PIP4P2 | phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2 | 0.28 |
| FSIP2 | fibrous sheath interacting protein 2 | 0.28 |
| ZNF136 | zinc finger protein 136 | 0.28 |
| MINDY4 | MINDY lysine 48 deubiquitinase 4 | 0.28 |
| LONP2 | lon peptidase 2, peroxisomal | 0.28 |
| DENND5A | DENN/MADD domain containing 5A | 0.27 |
| RWDD2A | RWD domain containing 2A | 0.27 |
| TGIF1 | TGFB-induced factor homeobox 1 | 0.27 |
| ZSCAN25 | zinc finger and SCAN domain containing 25 | 0.27 |
| SGSH | N-sulfoglucosamine sulfohydrolase | 0.27 |
| COMMD2 | COMM domain containing 2 | 0.26 |
| NABP2 | nucleic acid binding protein 2 | 0.26 |
| SEC24D | SEC24 family member D | 0.26 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.26 |
| MR1 | major histocompatibility complex, class I-related | 0.26 |
| RNASEH1 | ribonuclease H1 | 0.26 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal | 0.25 |
| SLC22A18 | solute carrier family 22, member 18 | 0.25 |
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) | 0.25 |
| PIM3 | Pim-3 proto-oncogene, serine/threonine kinase | 0.25 |
| ENO1 | enolase 1, (alpha) | 0.25 |
| CLUH | clustered mitochondria (cluA/CLU1) homolog | 0.25 |
| CACNA1E | calcium channel, voltage-dependent, R type, alpha 1E subunit | 0.25 |
| GYG1 | glycogenin 1 | 0.25 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.25 |
| FASTK | Fas-activated serine/threonine kinase | 0.25 |
| DCHS1 | dachsous cadherin-related 1 | 0.24 |
| FITM2 | fat storage-inducing transmembrane protein 2 | 0.24 |
| EPHA4 | EPH receptor A4 | 0.24 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FSTL1 | follistatin-like 1 | -3.05 |
| KSR2 | kinase suppressor of ras 2 | -2.26 |
| PIP | prolactin-induced protein | -1.25 |
| ABHD14A | abhydrolase domain containing 14A | -1.06 |
| KLHL23 | kelch-like family member 23 | -0.98 |
| HS6ST1 | heparan sulfate 6-O-sulfotransferase 1 | -0.93 |
| BCAM | basal cell adhesion molecule (Lutheran blood group) | -0.89 |
| LOXL2 | lysyl oxidase-like 2 | -0.88 |
| ZDHHC23 | zinc finger, DHHC-type containing 23 | -0.83 |
| IRF9 | interferon regulatory factor 9 | -0.76 |
| ARHGEF35 | Rho guanine nucleotide exchange factor (GEF) 35 | -0.76 |
| DCLK2 | doublecortin-like kinase 2 | -0.66 |
| GCC1 | GRIP and coiled-coil domain containing 1 | -0.65 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.61 |
| FADS3 | fatty acid desaturase 3 | -0.59 |
| SLC4A3 | solute carrier family 4 (anion exchanger), member 3 | -0.59 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.57 |
| PLIN2 | perilipin 2 | -0.56 |
| ABHD2 | abhydrolase domain containing 2 | -0.56 |
| ZMAT5 | zinc finger, matrin-type 5 | -0.56 |
| TMEM98 | transmembrane protein 98 | -0.54 |
| ITGAV | integrin, alpha V | -0.53 |
| CRY1 | cryptochrome circadian clock 1 | -0.49 |
| CHRD | chordin | -0.49 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | -0.49 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.48 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | -0.48 |
| ZNF672 | zinc finger protein 672 | -0.48 |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 | -0.45 |
| EPM2AIP1 | EPM2A (laforin) interacting protein 1 | -0.45 |
| CLGN | calmegin | -0.45 |
| KBTBD6 | kelch repeat and BTB (POZ) domain containing 6 | -0.44 |
| ZNF12 | zinc finger protein 12 | -0.44 |
| OTC | ornithine carbamoyltransferase | -0.43 |
| ZNF557 | zinc finger protein 557 | -0.43 |
| ERVMER34-1 | endogenous retrovirus group MER34, member 1 | -0.42 |
| OAF | OAF homolog (Drosophila) | -0.42 |
| FBXL4 | F-box and leucine-rich repeat protein 4 | -0.42 |
| ZBTB12 | zinc finger and BTB domain containing 12 | -0.41 |
| HIST2H2AA3 | histone cluster 2, H2aa3 | -0.41 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | -0.41 |
| PITPNM2 | phosphatidylinositol transfer protein, membrane-associated 2 | -0.39 |
| SLC30A9 | solute carrier family 30 (zinc transporter), member 9 | -0.39 |
| FGFBP1 | fibroblast growth factor binding protein 1 | -0.39 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.39 |
| LMBRD1 | LMBR1 domain containing 1 | -0.38 |
| MREG | melanoregulin | -0.37 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | -0.37 |
| SQLE | squalene epoxidase | -0.37 |
| HOXA7 | homeobox A7 | -0.36 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.36 |
| SPIRE2 | spire-type actin nucleation factor 2 | -0.36 |
| MOSPD3 | motile sperm domain containing 3 | -0.36 |
| DHCR24 | 24-dehydrocholesterol reductase | -0.35 |
| LINGO1 | leucine rich repeat and Ig domain containing 1 | -0.35 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | -0.35 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.35 |
| FBXW8 | F-box and WD repeat domain containing 8 | -0.35 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 | -0.34 |
| SGSM3 | small G protein signaling modulator 3 | -0.34 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | -0.34 |
| IRX4 | iroquois homeobox 4 | -0.34 |
| SERINC5 | serine incorporator 5 | -0.33 |
| ATF3 | activating transcription factor 3 | -0.33 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -0.33 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.33 |
| MEGF8 | multiple EGF-like-domains 8 | -0.33 |
| LMF1 | lipase maturation factor 1 | -0.33 |
| GNPTG | N-acetylglucosamine-1-phosphate transferase, gamma subunit | -0.33 |
| BMPR1B | bone morphogenetic protein receptor, type IB | -0.33 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.32 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | -0.32 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) | -0.32 |
| YAF2 | YY1 associated factor 2 | -0.31 |
| TCOF1 | Treacher Collins-Franceschetti syndrome 1 | -0.31 |
| C17ORF53 | chromosome 17 open reading frame 53 | -0.31 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | -0.31 |
| SPIN4 | spindlin family, member 4 | -0.31 |
| ANKRD52 | ankyrin repeat domain 52 | -0.3 |
| PWWP3A | PWWP domain containing 3A, DNA repair factor | -0.3 |
| NPTXR | neuronal pentraxin receptor | -0.3 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 | -0.3 |
| NAT9 | N-acetyltransferase 9 (GCN5-related, putative) | -0.3 |
| C7 | complement component 7 | -0.3 |
| HAPLN3 | hyaluronan and proteoglycan link protein 3 | -0.3 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 | -0.3 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.3 |
| ITGB5 | integrin, beta 5 | -0.3 |
| CILP2 | cartilage intermediate layer protein 2 | -0.3 |
| SLC6A17 | solute carrier family 6 (neutral amino acid transporter), member 17 | -0.3 |
| BMT2 | base methyltransferase of 25S rRNA 2 homolog | -0.29 |
| FAM219A | family with sequence similarity 219, member A | -0.29 |
| PTPRU | protein tyrosine phosphatase, receptor type, U | -0.29 |
| CYB5D2 | cytochrome b5 domain containing 2 | -0.29 |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) | -0.28 |
| DGAT1 | diacylglycerol O-acyltransferase 1 | -0.28 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.28 |
| ERICH5 | glutamate-rich 5 | -0.28 |
| GATA6 | GATA binding protein 6 | -0.28 |
