| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vemurafenib perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vemurafenib_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.100981 |
| POTEF | POTE ankyrin domain family, member F | 0.0745895 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0708181 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0632889 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0604968 |
| MSN | moesin | 0.0566161 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0544823 |
| CD44 | CD44 molecule (Indian blood group) | 0.0540835 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0493946 |
| BCL2L1 | BCL2-like 1 | 0.0482579 |
| EZR | ezrin | 0.0482092 |
| MYO10 | myosin X | 0.0470829 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0469401 |
| NDRG1 | N-myc downstream regulated 1 | 0.0441256 |
| ASPH | aspartate beta-hydroxylase | 0.0420214 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0407111 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.040093 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0368593 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0368336 |
| PTK2 | protein tyrosine kinase 2 | 0.0360277 |
| NRG1 | neuregulin 1 | 0.035727 |
| RASAL2 | RAS protein activator like 2 | 0.0356356 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0355734 |
| EPHA2 | EPH receptor A2 | 0.0350458 |
| PCDH1 | protocadherin 1 | 0.0350282 |
| SIK3 | SIK family kinase 3 | 0.0350237 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.034462 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0343474 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0338403 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0333958 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0326189 |
| FOSL1 | FOS-like antigen 1 | 0.0316374 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0311537 |
| PODXL | podocalyxin-like | 0.0307893 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0303599 |
| TGM2 | transglutaminase 2 | 0.0297606 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0284953 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.027855 |
| SMAD3 | SMAD family member 3 | 0.0272544 |
| RIN2 | Ras and Rab interactor 2 | 0.0266564 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0266005 |
| TPM3 | tropomyosin 3 | 0.0265907 |
| CEP170 | centrosomal protein 170kDa | 0.0264138 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0256747 |
| DOCK9 | dedicator of cytokinesis 9 | 0.025585 |
| EFHD2 | EF-hand domain family, member D2 | 0.025323 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0251676 |
| FOXO1 | forkhead box O1 | 0.0250336 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.0250145 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0248454 |
| JMJD1C | jumonji domain containing 1C | 0.0248192 |
| ANO6 | anoctamin 6 | 0.0244813 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0243079 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0241403 |
| AMOTL1 | angiomotin like 1 | 0.0241254 |
| FAM107B | family with sequence similarity 107, member B | 0.0240858 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0238745 |
| YBX3 | Y box binding protein 3 | 0.0237607 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.023753 |
| LAMA5 | laminin, alpha 5 | 0.0236758 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0235503 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0232659 |
| ARRDC3 | arrestin domain containing 3 | 0.0231658 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0229777 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0229159 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0228936 |
| ITGB4 | integrin, beta 4 | 0.0228783 |
| SLTM | SAFB-like, transcription modulator | 0.0227586 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0227253 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0227228 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0227022 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0225905 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0223317 |
| RPL21 | ribosomal protein L21 | 0.0223197 |
| CENPF | centromere protein F, 350/400kDa | 0.0221126 |
| TXNIP | thioredoxin interacting protein | 0.0219997 |
| APP | amyloid beta (A4) precursor protein | 0.0219491 |
| EXOC6B | exocyst complex component 6B | 0.0214398 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.021341 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0212967 |
| RTN4 | reticulon 4 | 0.0210549 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.020787 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0207609 |
| JAG1 | jagged 1 | 0.0203576 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0201115 |
| ITGA6 | integrin, alpha 6 | 0.0200187 |
| PDLIM1 | PDZ and LIM domain 1 | 0.0198521 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0196593 |
| FN1 | fibronectin 1 | 0.0194276 |
| EHBP1 | EH domain binding protein 1 | 0.0193311 |
| EFNA5 | ephrin-A5 | 0.0191318 |
| EMP1 | epithelial membrane protein 1 | 0.0190973 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0189694 |
| NF1 | neurofibromin 1 | 0.0189388 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0188856 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0187954 |
| METTL15 | methyltransferase like 15 | 0.0185786 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0185699 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.0184879 |
| GRAMD1B | GRAM domain containing 1B | 0.0184055 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.471302 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.199555 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.13928 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.132952 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0812453 |
| PTMA | prothymosin, alpha | -0.0761944 |
| AHNAK | AHNAK nucleoprotein | -0.07448 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0712479 |
| ENO1 | enolase 1, (alpha) | -0.0703555 |
| RPS8 | ribosomal protein S8 | -0.0692976 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.057272 |
| RPS25 | ribosomal protein S25 | -0.0565883 |
| HLA-B | major histocompatibility complex, class I, B | -0.0547313 |
| RPS24 | ribosomal protein S24 | -0.0538231 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0507784 |
| HM13 | histocompatibility (minor) 13 | -0.0503001 |
| RPS13 | ribosomal protein S13 | -0.0499535 |
| VCL | vinculin | -0.04905 |
| CANX | calnexin | -0.0474156 |
| SQSTM1 | sequestosome 1 | -0.0465342 |
| MTSS1 | metastasis suppressor 1 | -0.0464197 |
| INTS6 | integrator complex subunit 6 | -0.0458246 |
| PALLD | palladin, cytoskeletal associated protein | -0.0455913 |
| RPL37 | ribosomal protein L37 | -0.0442637 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0433063 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0432038 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0430777 |
| HLA-E | major histocompatibility complex, class I, E | -0.0420301 |
| RPL11 | ribosomal protein L11 | -0.041569 |
| B2M | beta-2-microglobulin | -0.0401472 |
| RPLP1 | ribosomal protein, large, P1 | -0.0371188 |
| GNAS | GNAS complex locus | -0.0369392 |
| H1-0 | H1.0 linker histone | -0.0366925 |
| PRSS23 | protease, serine, 23 | -0.035969 |
| RPL31 | ribosomal protein L31 | -0.035419 |
| RPS3 | ribosomal protein S3 | -0.0353976 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0340851 |
| RPL23 | ribosomal protein L23 | -0.0339514 |
| RPL35A | ribosomal protein L35a | -0.0339396 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0335186 |
| S100A10 | S100 calcium binding protein A10 | -0.0333828 |
| RPLP2 | ribosomal protein, large, P2 | -0.0332502 |
| TMSB4X | thymosin beta 4, X-linked | -0.0332332 |
| CD9 | CD9 molecule | -0.0327107 |
| RPL26 | ribosomal protein L26 | -0.0322903 |
| RPS21 | ribosomal protein S21 | -0.0313765 |
| FTL | ferritin, light polypeptide | -0.0313147 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0311738 |
| AOPEP | aminopeptidase O (putative) | -0.0306714 |
| RPL27A | ribosomal protein L27a | -0.0305607 |
| RPS27A | ribosomal protein S27a | -0.030531 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0305244 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0300923 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0293134 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0292262 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.028753 |
| CALB1 | calbindin 1, 28kDa | -0.0286784 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0279045 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.027824 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0276529 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0276468 |
| RPL34 | ribosomal protein L34 | -0.0274385 |
| CAVIN1 | caveolae associated protein 1 | -0.027281 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0271194 |
| RPS27 | ribosomal protein S27 | -0.0270739 |
| KIAA1217 | KIAA1217 | -0.0267749 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0265663 |
| RPL7A | ribosomal protein L7a | -0.0264234 |
| RPS6 | ribosomal protein S6 | -0.0263716 |
| FNIP1 | folliculin interacting protein 1 | -0.0262762 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0261598 |
| MEGF6 | multiple EGF-like-domains 6 | -0.0259356 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0258343 |
| RSF1 | remodeling and spacing factor 1 | -0.0258089 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | -0.0257374 |
| MTAP | methylthioadenosine phosphorylase | -0.025714 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.025339 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0251066 |
| ARF1 | ADP-ribosylation factor 1 | -0.0248039 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0247192 |
| DSG2 | desmoglein 2 | -0.0246831 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0244091 |
| DOK5 | docking protein 5 | -0.024095 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0240317 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0239579 |
| RPL30 | ribosomal protein L30 | -0.0237171 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0236431 |
| RPL12 | ribosomal protein L12 | -0.0234493 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.023352 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0233273 |
| UBC | ubiquitin C | -0.0230876 |
| RPS19 | ribosomal protein S19 | -0.0230636 |
| CLIC4 | chloride intracellular channel 4 | -0.0229988 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0229973 |
| RPS29 | ribosomal protein S29 | -0.0229277 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0226833 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.0225531 |
| MECOM | MDS1 and EVI1 complex locus | -0.0224857 |
| RPL19 | ribosomal protein L19 | -0.0224546 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0224125 |
