| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vemurafenib perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vemurafenib_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.191459 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.134139 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.123861 |
| EZR | ezrin | 0.121679 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0961912 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.096111 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0929509 |
| ANXA1 | annexin A1 | 0.0753897 |
| ATXN1 | ataxin 1 | 0.0743141 |
| EMP1 | epithelial membrane protein 1 | 0.070157 |
| LCN2 | lipocalin 2 | 0.0672261 |
| FNDC3B | fibronectin type III domain containing 3B | 0.066117 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0638512 |
| RNF213 | ring finger protein 213 | 0.0611507 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0561511 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0545462 |
| HDAC9 | histone deacetylase 9 | 0.0527736 |
| DST | dystonin | 0.0527436 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0510026 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0475623 |
| ACTG1 | actin gamma 1 | 0.0473253 |
| MCU | mitochondrial calcium uniporter | 0.0469538 |
| TJP1 | tight junction protein 1 | 0.0467148 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0445518 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0441063 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0437711 |
| POF1B | premature ovarian failure, 1B | 0.0435448 |
| MYO1E | myosin IE | 0.0432699 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0421618 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0418718 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0404317 |
| RUNX1 | runt-related transcription factor 1 | 0.0398355 |
| NDRG1 | N-myc downstream regulated 1 | 0.0396295 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0395801 |
| GDA | guanine deaminase | 0.0391133 |
| KLHL29 | kelch-like family member 29 | 0.0387242 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0387203 |
| MYOF | myoferlin | 0.0371765 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0370369 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0365807 |
| CLDN4 | claudin 4 | 0.0363788 |
| FRMD5 | FERM domain containing 5 | 0.0355167 |
| INTS6 | integrator complex subunit 6 | 0.0354448 |
| SLC38A2 | solute carrier family 38, member 2 | 0.035334 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0351142 |
| MYO5B | myosin VB | 0.0348081 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0345561 |
| EGFR | epidermal growth factor receptor | 0.0329383 |
| PGK1 | phosphoglycerate kinase 1 | 0.0327169 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0327143 |
| KLF6 | Kruppel-like factor 6 | 0.0325804 |
| RASEF | RAS and EF-hand domain containing | 0.0324381 |
| PMM2 | phosphomannomutase 2 | 0.0323245 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.032069 |
| COBL | cordon-bleu WH2 repeat protein | 0.0319071 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0317134 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0315972 |
| SQSTM1 | sequestosome 1 | 0.031264 |
| CUX1 | cut-like homeobox 1 | 0.0308854 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0307061 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0304543 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.030453 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.0302947 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0292284 |
| ASPH | aspartate beta-hydroxylase | 0.0290528 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0281726 |
| SIK3 | SIK family kinase 3 | 0.0280141 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0278354 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.0271598 |
| SP100 | SP100 nuclear antigen | 0.0263461 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.026293 |
| FOXO3 | forkhead box O3 | 0.0259176 |
| FTL | ferritin, light polypeptide | 0.0255511 |
| EFNA5 | ephrin-A5 | 0.0253042 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0249261 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0245819 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0245559 |
| SLK | STE20-like kinase | 0.0243226 |
| GOLGB1 | golgin B1 | 0.0241354 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0238468 |
| FNIP1 | folliculin interacting protein 1 | 0.023565 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0230648 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0229823 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0229804 |
| LAMA4 | laminin, alpha 4 | 0.0229477 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0227129 |
| JUN | jun proto-oncogene | 0.0226989 |
| HKDC1 | hexokinase domain containing 1 | 0.0224286 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0223999 |
| SLTM | SAFB-like, transcription modulator | 0.022266 |
| SGMS2 | sphingomyelin synthase 2 | 0.0222478 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) | 0.0221846 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0219498 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0218711 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0218098 |
| HBP1 | HMG-box transcription factor 1 | 0.0215073 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0212428 |
| SULF2 | sulfatase 2 | 0.020973 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.020877 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.020531 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.194873 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.194538 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.10825 |
| ANLN | anillin, actin binding protein | -0.0851987 |
| PTMA | prothymosin, alpha | -0.0819806 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0713546 |
| B2M | beta-2-microglobulin | -0.0663809 |
| EPCAM | epithelial cell adhesion molecule | -0.0658157 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0636346 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0608472 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0552629 |
| CLTC | clathrin, heavy chain (Hc) | -0.0520275 |
| XPO1 | exportin 1 | -0.0500913 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0483093 |
| RPS2 | ribosomal protein S2 | -0.0480675 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0479907 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0466442 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0456945 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0452216 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0431816 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0428596 |
| DIAPH3 | diaphanous-related formin 3 | -0.0424535 |
| MKI67 | marker of proliferation Ki-67 | -0.0414967 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.041263 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0406117 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0406077 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0405784 |
| HYOU1 | hypoxia up-regulated 1 | -0.040509 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0399046 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.039746 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0394109 |
| WWC1 | WW and C2 domain containing 1 | -0.0390014 |
| CANX | calnexin | -0.0384426 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0383689 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0376709 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0376355 |
| KRT18 | keratin 18, type I | -0.0373056 |
| S100A6 | S100 calcium binding protein A6 | -0.0370852 |
| RPS3 | ribosomal protein S3 | -0.0358895 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0357354 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.0348589 |
| PRSS3 | protease, serine, 3 | -0.0345694 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0338414 |
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | -0.0334602 |
| PHIP | pleckstrin homology domain interacting protein | -0.0334539 |
| TPX2 | TPX2, microtubule-associated | -0.0334239 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.033422 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0331733 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0325018 |
| PCBP2 | poly(rC) binding protein 2 | -0.0321618 |
| RRBP1 | ribosome binding protein 1 | -0.0320525 |
| H1-0 | H1.0 linker histone | -0.0320464 |
| STK24 | serine/threonine kinase 24 | -0.0313871 |
| LOC112694756 | uncharaterized LOC112694756 | -0.031153 |
| S100A9 | S100 calcium binding protein A9 | -0.0310547 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0307057 |
| INSIG1 | insulin induced gene 1 | -0.0305858 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0303397 |
| ARCN1 | archain 1 | -0.030328 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0303267 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0301108 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0299958 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0297782 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0297212 |
| SET | SET nuclear proto-oncogene | -0.0294129 |
| BRCA1 | breast cancer 1, early onset | -0.0290074 |
| OGA | O-GlcNAcase | -0.0288759 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0287796 |
| S100A10 | S100 calcium binding protein A10 | -0.0287536 |
| HMGB2 | high mobility group box 2 | -0.0286802 |
| YAP1 | Yes-associated protein 1 | -0.028533 |
| RPS19 | ribosomal protein S19 | -0.0283731 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0281069 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0278622 |
| PREPL | prolyl endopeptidase-like | -0.0278357 |
| RPS25 | ribosomal protein S25 | -0.0276927 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0276581 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0272596 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0270417 |
| COG5 | component of oligomeric golgi complex 5 | -0.0269279 |
| ALDOC | aldolase C, fructose-bisphosphate | -0.0268223 |
| RNF43 | ring finger protein 43 | -0.0267846 |
| GSK3B | glycogen synthase kinase 3 beta | -0.026776 |
| NF1 | neurofibromin 1 | -0.0267135 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | -0.026681 |
| THOC2 | THO complex 2 | -0.0266361 |
| WDR45B | WD repeat domain 45B | -0.0264461 |
| BCL2L1 | BCL2-like 1 | -0.0262912 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.026264 |
| FDPS | farnesyl diphosphate synthase | -0.026211 |
| ZNF292 | zinc finger protein 292 | -0.0262079 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0261678 |
| SELENOK | selenoprotein K | -0.026037 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0260137 |
| RPS21 | ribosomal protein S21 | -0.0259804 |
| RPL19 | ribosomal protein L19 | -0.0258712 |
| RPLP1 | ribosomal protein, large, P1 | -0.0258343 |
| LIMA1 | LIM domain and actin binding 1 | -0.0258069 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0257967 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0257506 |
