| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vemurafenib perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Vemurafenib_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.154638 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.126436 |
| GRB10 | growth factor receptor-bound protein 10 | 0.112033 |
| VIM | vimentin | 0.109653 |
| STC1 | stanniocalcin 1 | 0.0912959 |
| NDRG1 | N-myc downstream regulated 1 | 0.0864754 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0832772 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0824145 |
| CDH13 | cadherin 13 | 0.0748596 |
| NAV2 | neuron navigator 2 | 0.0744394 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0696486 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0694978 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0694003 |
| PCBP2 | poly(rC) binding protein 2 | 0.0692592 |
| EFNA5 | ephrin-A5 | 0.0673947 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0672595 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0656636 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0654315 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0637851 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0621422 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0609851 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0599783 |
| LOXL2 | lysyl oxidase-like 2 | 0.0586174 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0582199 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0577689 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0561068 |
| MTSS1 | metastasis suppressor 1 | 0.0560594 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0552913 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0551798 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0539036 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0536773 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0524318 |
| HMGA2 | high mobility group AT-hook 2 | 0.0500538 |
| USP34 | ubiquitin specific peptidase 34 | 0.0496143 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0487084 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0486659 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0461003 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0441741 |
| LOX | lysyl oxidase | 0.0440782 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0422178 |
| VEGFA | vascular endothelial growth factor A | 0.042065 |
| DTNA | dystrobrevin, alpha | 0.0416655 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0413783 |
| PTK2 | protein tyrosine kinase 2 | 0.0406147 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0392957 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0389277 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0379171 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0376874 |
| ASPH | aspartate beta-hydroxylase | 0.0375973 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0375457 |
| HMGA1 | high mobility group AT-hook 1 | 0.0375159 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0370657 |
| AADAC | arylacetamide deacetylase | 0.0349843 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0347225 |
| ATXN1 | ataxin 1 | 0.0346701 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0346356 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0334697 |
| CD44 | CD44 molecule (Indian blood group) | 0.0331137 |
| ANGPTL4 | angiopoietin-like 4 | 0.033051 |
| FLNB | filamin B, beta | 0.0328931 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0327351 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0324407 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0324105 |
| FAM107B | family with sequence similarity 107, member B | 0.0323291 |
| SIK3 | SIK family kinase 3 | 0.0315726 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0313494 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.031261 |
| EGR1 | early growth response 1 | 0.0311351 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0302452 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0301221 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0301009 |
| SEC24A | SEC24 family member A | 0.0300159 |
| MYO10 | myosin X | 0.0299402 |
| CA12 | carbonic anhydrase XII | 0.0297518 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0296957 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0296457 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.029562 |
| SMAD3 | SMAD family member 3 | 0.0294562 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0289081 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0287713 |
| LDHA | lactate dehydrogenase A | 0.028698 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0286746 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0284794 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0284332 |
| IL1B | interleukin 1, beta | 0.0283467 |
| TGM2 | transglutaminase 2 | 0.028297 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0282235 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0278021 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0277908 |
| GOLGA4 | golgin A4 | 0.0277544 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0275585 |
| RUNX1 | runt-related transcription factor 1 | 0.0274945 |
| PKM | pyruvate kinase, muscle | 0.0271247 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0270408 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0268952 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0263682 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0263064 |
| MYADM | myeloid-associated differentiation marker | 0.0262101 |
| MT2A | metallothionein 2A | 0.0261118 |
| CLMP | CXADR-like membrane protein | 0.0260224 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0903699 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0707515 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0603421 |
| GLCCI1 | glucocorticoid induced 1 | -0.0512587 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.045973 |
| RAD51B | RAD51 paralog B | -0.0374557 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0355402 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0354736 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0325295 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0305467 |
| AOPEP | aminopeptidase O (putative) | -0.0286777 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0286721 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.02842 |
| OSMR | oncostatin M receptor | -0.027692 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0274702 |
| ETV6 | ets variant 6 | -0.0269574 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0269303 |
| DST | dystonin | -0.0267907 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0263831 |
| GPC6 | glypican 6 | -0.0263056 |
| CANX | calnexin | -0.0262695 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0260586 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0257962 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0257125 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0247112 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0245006 |
| KYNU | kynureninase | -0.0244566 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0242807 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0232845 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0228765 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0214079 |
| FAM20C | family with sequence similarity 20, member C | -0.021072 |
| SUMF1 | sulfatase modifying factor 1 | -0.0208938 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0205581 |
| MECOM | MDS1 and EVI1 complex locus | -0.0203089 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0200868 |
| PRELID2 | PRELI domain containing 2 | -0.0198076 |
| FNBP1 | formin binding protein 1 | -0.0197757 |
| HDLBP | high density lipoprotein binding protein | -0.019648 |
| H1-0 | H1.0 linker histone | -0.0193753 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0192899 |
| ZNF804A | zinc finger protein 804A | -0.0192664 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0192469 |
| DPYD | dihydropyrimidine dehydrogenase | -0.019246 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0189438 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0185432 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0184426 |
| RBM39 | RNA binding motif protein 39 | -0.0184334 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0182905 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0181038 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0180016 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0178382 |
| RNF24 | ring finger protein 24 | -0.017435 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0173098 |
| CEP95 | centrosomal protein 95kDa | -0.0171331 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0169457 |
| CAB39 | calcium binding protein 39 | -0.0165398 |
| ZFR | zinc finger RNA binding protein | -0.0163692 |
| KSR1 | kinase suppressor of ras 1 | -0.0159888 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0159475 |
| MEIS1 | Meis homeobox 1 | -0.0158762 |
| GALK2 | galactokinase 2 | -0.0157337 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0155857 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0153996 |
| VCL | vinculin | -0.0153642 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.015141 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.015054 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0149142 |
| ANAPC5 | anaphase promoting complex subunit 5 | -0.014906 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0148279 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0147432 |
| LRRC49 | leucine rich repeat containing 49 | -0.0146939 |
| FRMD5 | FERM domain containing 5 | -0.0146044 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | -0.0143505 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.014031 |
| PHF3 | PHD finger protein 3 | -0.0138355 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0137774 |
| MTERF1 | mitochondrial transcription termination factor 1 | -0.0137299 |
| PHF14 | PHD finger protein 14 | -0.0135921 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0134781 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.013418 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0133093 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0130472 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0129977 |
| APP | amyloid beta (A4) precursor protein | -0.0129452 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0128893 |
| ENOSF1 | enolase superfamily member 1 | -0.0128574 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0128204 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.012814 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0127925 |
| MAP4 | microtubule-associated protein 4 | -0.0127662 |
| RNF149 | ring finger protein 149 | -0.0126842 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0126238 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0126101 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0125721 |
| FOXP2 | forkhead box P2 | -0.0125309 |
| ICA1 | islet cell autoantigen 1, 69kDa | -0.0124706 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0124451 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0124073 |
| CDK17 | cyclin-dependent kinase 17 | -0.0123881 |
