| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vemurafenib perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vemurafenib_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0279813 |
| HDAC9 | histone deacetylase 9 | 0.0271503 |
| FER1L6 | fer-1-like family member 6 | 0.0256603 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0241736 |
| SGMS2 | sphingomyelin synthase 2 | 0.0230268 |
| FOXP1 | forkhead box P1 | 0.0224953 |
| MYO5C | myosin VC | 0.0203388 |
| MKI67 | marker of proliferation Ki-67 | 0.0202092 |
| DIAPH3 | diaphanous-related formin 3 | 0.0201402 |
| ANLN | anillin, actin binding protein | 0.0197153 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0193772 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0186273 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.0186081 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0181136 |
| ZNF608 | zinc finger protein 608 | 0.0171544 |
| MLIP | muscular LMNA-interacting protein | 0.0163736 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0162486 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.0161022 |
| GLI3 | GLI family zinc finger 3 | 0.0155801 |
| ANXA1 | annexin A1 | 0.015552 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.015159 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0150199 |
| ZNF438 | zinc finger protein 438 | 0.0149756 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0149088 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0142001 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 0.0137943 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0135833 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0132219 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0131289 |
| MYOF | myoferlin | 0.0129529 |
| CORO1C | coronin, actin binding protein, 1C | 0.0129498 |
| INTS6 | integrator complex subunit 6 | 0.0128308 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0125615 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.012408 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0121566 |
| ARHGAP25 | Rho GTPase activating protein 25 | 0.0117592 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0117518 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0114037 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0113569 |
| NAV2 | neuron navigator 2 | 0.0107078 |
| AFG2A | AFG2 AAA ATPase homolog A | 0.0106123 |
| UNC13A | unc-13 homolog A (C. elegans) | 0.0105537 |
| TJP1 | tight junction protein 1 | 0.0105068 |
| CEP112 | centrosomal protein 112kDa | 0.0103103 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0101467 |
| DNMBP | dynamin binding protein | 0.0101369 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0100087 |
| KIF11 | kinesin family member 11 | 0.00998718 |
| SP100 | SP100 nuclear antigen | 0.00987472 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.00972939 |
| PDE7B | phosphodiesterase 7B | 0.00961098 |
| SSBP3 | single stranded DNA binding protein 3 | 0.00938923 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.00930745 |
| BCOR | BCL6 corepressor | 0.00930579 |
| RRM2 | ribonucleotide reductase M2 | 0.0093011 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.00924222 |
| ITGA10 | integrin, alpha 10 | 0.00921168 |
| RAD18 | RAD18 E3 ubiquitin protein ligase | 0.00920368 |
| EXOC2 | exocyst complex component 2 | 0.00883318 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00861066 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | 0.00859821 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.00858227 |
| TPX2 | TPX2, microtubule-associated | 0.00857781 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.00849761 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 | 0.00848993 |
| MCM8 | minichromosome maintenance complex component 8 | 0.00845333 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.00819569 |
| AEBP2 | AE binding protein 2 | 0.00807463 |
| SNX19 | sorting nexin 19 | 0.00804809 |
| MMS22L | MMS22-like, DNA repair protein | 0.00787954 |
| CMIP | c-Maf inducing protein | 0.00784472 |
| STX18 | syntaxin 18 | 0.00782506 |
| KIF14 | kinesin family member 14 | 0.00781368 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00779217 |
| ELMO1 | engulfment and cell motility 1 | 0.00778455 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.00775193 |
| CIP2A | cellular inhibitor of PP2A | 0.00771305 |
| CHI3L2 | chitinase 3-like 2 | 0.00766914 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00763132 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.00758597 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.00757195 |
| RSPRY1 | ring finger and SPRY domain containing 1 | 0.00752343 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00750303 |
| KNTC1 | kinetochore associated 1 | 0.00740143 |
| XIRP2 | xin actin binding repeat containing 2 | 0.00738891 |
| CDCP1 | CUB domain containing protein 1 | 0.00738127 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 | 0.00730781 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.00729178 |
| ZNF532 | zinc finger protein 532 | 0.00726322 |
| ABCA10 | ATP-binding cassette, sub-family A (ABC1), member 10 | 0.00717155 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0071661 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0070859 |
| CKAP5 | cytoskeleton associated protein 5 | 0.00707796 |
| VRK1 | vaccinia related kinase 1 | 0.0070706 |
| SPC25 | SPC25, NDC80 kinetochore complex component | 0.00704734 |
| PRKCE | protein kinase C, epsilon | 0.00704083 |
| TBCA | tubulin folding cofactor A | 0.00689496 |
| HELLS | helicase, lymphoid-specific | 0.0068841 |
| CENPP | centromere protein P | 0.00683413 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.00670195 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.209108 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.171895 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0892305 |
| RPS6 | ribosomal protein S6 | -0.0868846 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0724802 |
| GOLGA4 | golgin A4 | -0.0654205 |
| TXNRD1 | thioredoxin reductase 1 | -0.0633466 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0625486 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0622165 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0620439 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0615808 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.061532 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0582946 |
| RPL26 | ribosomal protein L26 | -0.0561523 |
| RPS8 | ribosomal protein S8 | -0.0556891 |
| S100A6 | S100 calcium binding protein A6 | -0.0554392 |
| B2M | beta-2-microglobulin | -0.0535709 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0533194 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0530267 |
| TMSB4X | thymosin beta 4, X-linked | -0.0524587 |
| RPL11 | ribosomal protein L11 | -0.051764 |
| ENO1 | enolase 1, (alpha) | -0.0510492 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0504213 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0489286 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0476832 |
| FLNB | filamin B, beta | -0.0476786 |
| ZNF292 | zinc finger protein 292 | -0.0463641 |
| ACTG1 | actin gamma 1 | -0.0457158 |
| RPL37A | ribosomal protein L37a | -0.0452106 |
| RPL35A | ribosomal protein L35a | -0.0445653 |
| RBM39 | RNA binding motif protein 39 | -0.0443672 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0439323 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0438696 |
| RPL19 | ribosomal protein L19 | -0.0434462 |
| RPL12 | ribosomal protein L12 | -0.0427461 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0417086 |
| RTN4 | reticulon 4 | -0.041416 |
| RPS2 | ribosomal protein S2 | -0.0403879 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0403768 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0390925 |
| RPLP1 | ribosomal protein, large, P1 | -0.0387743 |
| SQSTM1 | sequestosome 1 | -0.0384479 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.038436 |
| RPS12 | ribosomal protein S12 | -0.038242 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0382107 |
| NF1 | neurofibromin 1 | -0.0381038 |
| RPS3 | ribosomal protein S3 | -0.0373372 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0370862 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0367209 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0360668 |
| LDHA | lactate dehydrogenase A | -0.0351666 |
| RPLP2 | ribosomal protein, large, P2 | -0.0351562 |
| ANK2 | ankyrin 2, neuronal | -0.0348111 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0347451 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0346937 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0345493 |
| RPS19 | ribosomal protein S19 | -0.0341537 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0337205 |
| RPS27A | ribosomal protein S27a | -0.0337135 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0336304 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0336198 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0335106 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0334618 |
| RPL36 | ribosomal protein L36 | -0.0332335 |
| RPS23 | ribosomal protein S23 | -0.0332118 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0326139 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0320887 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0316045 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0314305 |
| PKM | pyruvate kinase, muscle | -0.031376 |
| PYGB | phosphorylase, glycogen; brain | -0.0312987 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0309823 |
| RPL34 | ribosomal protein L34 | -0.0307697 |
| RPL13A | ribosomal protein L13a | -0.0306898 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.030399 |
| RPLP0 | ribosomal protein, large, P0 | -0.0301781 |
| DSTN | destrin (actin depolymerizing factor) | -0.0298442 |
| MAP4 | microtubule-associated protein 4 | -0.0297725 |
| JMJD1C | jumonji domain containing 1C | -0.0297469 |
| RPS13 | ribosomal protein S13 | -0.029726 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.029272 |
| QKI | QKI, KH domain containing, RNA binding | -0.0292024 |
| PARD3 | par-3 family cell polarity regulator | -0.0291205 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0290192 |
| NBEA | neurobeachin | -0.0289331 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.028895 |
| TMEM65 | transmembrane protein 65 | -0.0286159 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0284872 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0284748 |
| RPL7A | ribosomal protein L7a | -0.0283763 |
| FTL | ferritin, light polypeptide | -0.0283083 |
| RPL7 | ribosomal protein L7 | -0.0282837 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0282525 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0279734 |
| NBAS | neuroblastoma amplified sequence | -0.0276919 |
| EFNA5 | ephrin-A5 | -0.0276343 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.027607 |
| RPL9 | ribosomal protein L9 | -0.0275854 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0275111 |
| RPS25 | ribosomal protein S25 | -0.0273241 |
