| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vemurafenib perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Vemurafenib_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.208598 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.172201 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.128163 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0975323 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0914969 |
| NAV2 | neuron navigator 2 | 0.088921 |
| HDAC9 | histone deacetylase 9 | 0.0873859 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0847364 |
| CADM1 | cell adhesion molecule 1 | 0.0769547 |
| SPAG9 | sperm associated antigen 9 | 0.0662688 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0656629 |
| NDRG1 | N-myc downstream regulated 1 | 0.0636269 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0619309 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0610269 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0601025 |
| SFTPA2 | surfactant protein A2 | 0.0579447 |
| FNDC3B | fibronectin type III domain containing 3B | 0.057669 |
| FNIP1 | folliculin interacting protein 1 | 0.0542507 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0539265 |
| MYOF | myoferlin | 0.0531652 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0530128 |
| HELZ | helicase with zinc finger | 0.0527149 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0525065 |
| GOLGA4 | golgin A4 | 0.0520155 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0518509 |
| RND3 | Rho family GTPase 3 | 0.0495119 |
| FMNL2 | formin-like 2 | 0.0490621 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0477243 |
| ZNF292 | zinc finger protein 292 | 0.0463999 |
| OPTN | optineurin | 0.0461992 |
| ARRDC3 | arrestin domain containing 3 | 0.0455486 |
| PGK1 | phosphoglycerate kinase 1 | 0.0450009 |
| JMJD1C | jumonji domain containing 1C | 0.0440467 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.042508 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0421418 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0417955 |
| ADM | adrenomedullin | 0.04167 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0411402 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0402091 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.040105 |
| PRELID2 | PRELI domain containing 2 | 0.039985 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0396221 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0390276 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0376816 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.037326 |
| PDE10A | phosphodiesterase 10A | 0.0371028 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0352842 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0349258 |
| ANXA1 | annexin A1 | 0.0348216 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0342488 |
| CALR | calreticulin | 0.0342033 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0341004 |
| NGLY1 | N-glycanase 1 | 0.0335101 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0333909 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0329398 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0326725 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0321593 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0320541 |
| DST | dystonin | 0.0319635 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0315638 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0310185 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0306496 |
| EZR | ezrin | 0.0297432 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0295971 |
| MMP12 | matrix metallopeptidase 12 | 0.0295248 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0294852 |
| FOXO3 | forkhead box O3 | 0.029482 |
| WTAP | Wilms tumor 1 associated protein | 0.0294112 |
| DUSP10 | dual specificity phosphatase 10 | 0.0289646 |
| ARFGEF3 | ARFGEF family member 3 | 0.0289551 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0287484 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0286388 |
| USP37 | ubiquitin specific peptidase 37 | 0.0284451 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0283235 |
| SNX9 | sorting nexin 9 | 0.0282084 |
| CCBE1 | collagen and calcium binding EGF domains 1 | 0.0274843 |
| FLNA | filamin A, alpha | 0.0272809 |
| RPS4X | ribosomal protein S4, X-linked | 0.0271646 |
| RYBP | RING1 and YY1 binding protein | 0.027146 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0265618 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0264715 |
| FBXO32 | F-box protein 32 | 0.0264703 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0264463 |
| YEATS2 | YEATS domain containing 2 | 0.0263443 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0262161 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0256432 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0255041 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0254852 |
| TRAM2 | translocation associated membrane protein 2 | 0.0254424 |
| ANO6 | anoctamin 6 | 0.0250693 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0246663 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0242008 |
| RLF | rearranged L-myc fusion | 0.0238806 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0236959 |
| OGA | O-GlcNAcase | 0.0236931 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | 0.0236265 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0235501 |
| ATP13A3 | ATPase type 13A3 | 0.0235453 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0234016 |
| KIF13A | kinesin family member 13A | 0.0233962 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | -0.17098 |
| GLIS3 | GLIS family zinc finger 3 | -0.15957 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.154835 |
| BICC1 | BicC family RNA binding protein 1 | -0.120409 |
| VIM | vimentin | -0.11555 |
| FRMD4A | FERM domain containing 4A | -0.102897 |
| HMGA2 | high mobility group AT-hook 2 | -0.0776247 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0757294 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0741998 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.07204 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0626569 |
| CD44 | CD44 molecule (Indian blood group) | -0.0596715 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0579403 |
| HLA-B | major histocompatibility complex, class I, B | -0.0526467 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0510503 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0506828 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0486557 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.047623 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0464755 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0414033 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0395703 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0389136 |
| NABP1 | nucleic acid binding protein 1 | -0.038255 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0379835 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0378038 |
| VMP1 | vacuole membrane protein 1 | -0.0364809 |
| THBS1 | thrombospondin 1 | -0.0360325 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0347694 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0346866 |
| PALLD | palladin, cytoskeletal associated protein | -0.0343397 |
| FAM20C | family with sequence similarity 20, member C | -0.0340983 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0327228 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0322417 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0310474 |
| RAI14 | retinoic acid induced 14 | -0.0309401 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0305852 |
| OSMR | oncostatin M receptor | -0.0304949 |
| NAV1 | neuron navigator 1 | -0.0302065 |
| SMAD3 | SMAD family member 3 | -0.0302022 |
| RTN4 | reticulon 4 | -0.0297968 |
| MKI67 | marker of proliferation Ki-67 | -0.0289702 |
| NRP1 | neuropilin 1 | -0.028953 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0285969 |
| HLA-A | major histocompatibility complex, class I, A | -0.0285951 |
| TPM1 | tropomyosin 1 (alpha) | -0.0283809 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0278344 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0277687 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0277212 |
| RPL35A | ribosomal protein L35a | -0.0274508 |
| FN1 | fibronectin 1 | -0.0273773 |
| ACTN1 | actinin, alpha 1 | -0.027076 |
| EGR1 | early growth response 1 | -0.0269515 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0264251 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0259404 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0257849 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0256329 |
| COL1A1 | collagen, type I, alpha 1 | -0.0253471 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0250798 |
| RIGI | RNA sensor RIG-I | -0.0247428 |
| CENPF | centromere protein F, 350/400kDa | -0.0246593 |
| SH3RF2 | SH3 domain containing ring finger 2 | -0.0244601 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0244413 |
| EHBP1 | EH domain binding protein 1 | -0.0244233 |
| COL1A2 | collagen, type I, alpha 2 | -0.0243439 |
| TPM4 | tropomyosin 4 | -0.0241072 |
| CTSD | cathepsin D | -0.0236571 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0236203 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0232425 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0231337 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0230848 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0228836 |
| AHNAK | AHNAK nucleoprotein | -0.0226729 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0226275 |
| PMP22 | peripheral myelin protein 22 | -0.0222838 |
| STK17A | serine/threonine kinase 17a | -0.0217918 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0214179 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0214103 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0213547 |
| JAK2 | Janus kinase 2 | -0.0213465 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | -0.0209113 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0208301 |
| FTL | ferritin, light polypeptide | -0.0207691 |
| RAD51B | RAD51 paralog B | -0.0204943 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0204815 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0203949 |
| CDCP1 | CUB domain containing protein 1 | -0.0203863 |
| CDK17 | cyclin-dependent kinase 17 | -0.0203817 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0203708 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0201714 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0201687 |
| TNNC1 | troponin C type 1 (slow) | -0.0198876 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0197433 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0193397 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0192703 |
| CNTN6 | contactin 6 | -0.019247 |
| TENM2 | teneurin transmembrane protein 2 | -0.0191569 |
| RRBP1 | ribosome binding protein 1 | -0.0191104 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0190535 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0190374 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0189403 |
