| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vemurafenib perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vemurafenib_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.08753 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0648315 |
| ARRDC3 | arrestin domain containing 3 | 0.0576336 |
| CD44 | CD44 molecule (Indian blood group) | 0.0574859 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0504226 |
| NDRG1 | N-myc downstream regulated 1 | 0.0464846 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0457782 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0437188 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0399095 |
| RTN4 | reticulon 4 | 0.0388151 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0377525 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0347251 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0338681 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0326751 |
| MSN | moesin | 0.0326382 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0325091 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0323552 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0319175 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0314612 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.031434 |
| ADM | adrenomedullin | 0.0314201 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0307141 |
| KYNU | kynureninase | 0.0303485 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0300335 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0294802 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0294449 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0293077 |
| FAT1 | FAT atypical cadherin 1 | 0.0290837 |
| RLF | rearranged L-myc fusion | 0.0288122 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0287933 |
| SMAD3 | SMAD family member 3 | 0.0285892 |
| AHR | aryl hydrocarbon receptor | 0.0285255 |
| TRAM2 | translocation associated membrane protein 2 | 0.0284197 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0282634 |
| ZNF292 | zinc finger protein 292 | 0.0281938 |
| TXNIP | thioredoxin interacting protein | 0.0275708 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.02731 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0266714 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0266659 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0265525 |
| TXNRD1 | thioredoxin reductase 1 | 0.0263335 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0262322 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0260159 |
| CCNL1 | cyclin L1 | 0.0257736 |
| COL1A1 | collagen, type I, alpha 1 | 0.0255779 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0252864 |
| MKI67 | marker of proliferation Ki-67 | 0.0252402 |
| EZR | ezrin | 0.0248668 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0247564 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0247471 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0246305 |
| RNF24 | ring finger protein 24 | 0.0244589 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0244093 |
| MEF2A | myocyte enhancer factor 2A | 0.0236079 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0235092 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0234483 |
| KIF13A | kinesin family member 13A | 0.0232287 |
| TPM3 | tropomyosin 3 | 0.023179 |
| SPAG9 | sperm associated antigen 9 | 0.0230137 |
| ANXA1 | annexin A1 | 0.0230012 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0229587 |
| RNF145 | ring finger protein 145 | 0.0227744 |
| PKM | pyruvate kinase, muscle | 0.0223521 |
| MATR3 | matrin 3 | 0.0222992 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0221496 |
| COL1A2 | collagen, type I, alpha 2 | 0.0220979 |
| CDK19 | cyclin-dependent kinase 19 | 0.0218662 |
| EGR1 | early growth response 1 | 0.0216319 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0213025 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0212703 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0209796 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.020916 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0208991 |
| DST | dystonin | 0.0208243 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0205717 |
| TNPO3 | transportin 3 | 0.0203214 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0201796 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0201258 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0200394 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0199326 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0198628 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0197887 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0197045 |
| CCNT2 | cyclin T2 | 0.0194815 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0193994 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0192242 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0191526 |
| CCDC47 | coiled-coil domain containing 47 | 0.0190424 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0189936 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0189883 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0189165 |
| SLMAP | sarcolemma associated protein | 0.0189088 |
| JUN | jun proto-oncogene | 0.0188757 |
| ATP13A3 | ATPase type 13A3 | 0.01878 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.0185761 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0185721 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0184881 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0184279 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0183823 |
| FLNA | filamin A, alpha | 0.0183468 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.181559 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.167857 |
| CDH13 | cadherin 13 | -0.122445 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.113643 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.113 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.10203 |
| HLA-B | major histocompatibility complex, class I, B | -0.0995152 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0946343 |
| PRSS23 | protease, serine, 23 | -0.0942041 |
| VIM | vimentin | -0.0846427 |
| HMGA2 | high mobility group AT-hook 2 | -0.0789901 |
| AHNAK | AHNAK nucleoprotein | -0.077461 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0767115 |
| CANX | calnexin | -0.0722674 |
| VCL | vinculin | -0.0688993 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0650745 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0637062 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0629234 |
| COL5A1 | collagen, type V, alpha 1 | -0.0620697 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.058027 |
| LOX | lysyl oxidase | -0.0578935 |
| STC1 | stanniocalcin 1 | -0.0578891 |
| RAI14 | retinoic acid induced 14 | -0.0575184 |
| EFNA5 | ephrin-A5 | -0.0573373 |
| TNS3 | tensin 3 | -0.0573316 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0572089 |
| EGFR | epidermal growth factor receptor | -0.0564801 |
| PRELID2 | PRELI domain containing 2 | -0.0557894 |
| NRXN3 | neurexin 3 | -0.0549372 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0539319 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0515354 |
| IL6 | interleukin 6 | -0.0509271 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0500508 |
| COL6A2 | collagen, type VI, alpha 2 | -0.049908 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0493321 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0484611 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0482571 |
| CDK13 | cyclin-dependent kinase 13 | -0.0460154 |
| HDLBP | high density lipoprotein binding protein | -0.0456199 |
| KAZN | kazrin, periplakin interacting protein | -0.0455244 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0422758 |
| TPM4 | tropomyosin 4 | -0.0421452 |
| FBXO11 | F-box protein 11 | -0.0418259 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.041095 |
| HLA-A | major histocompatibility complex, class I, A | -0.0406129 |
| EXOC4 | exocyst complex component 4 | -0.0378778 |
| COG6 | component of oligomeric golgi complex 6 | -0.0376069 |
| SDC4 | syndecan 4 | -0.0372766 |
| RAD51B | RAD51 paralog B | -0.036929 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.036505 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.036299 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0360111 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0355736 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0349693 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0349442 |
| GPR173 | G protein-coupled receptor 173 | -0.0326992 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.032391 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0321418 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0319082 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.03182 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0317011 |
| HLA-C | major histocompatibility complex, class I, C | -0.030664 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0305199 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0300591 |
| TMSB10 | thymosin beta 10 | -0.0296414 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | -0.0294597 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0292262 |
| B2M | beta-2-microglobulin | -0.0289702 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0286593 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0285577 |
| COL7A1 | collagen, type VII, alpha 1 | -0.028379 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0278638 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0275559 |
| GOLGB1 | golgin B1 | -0.0274885 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0272211 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0270763 |
| EXT1 | exostosin glycosyltransferase 1 | -0.026677 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0266288 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.026569 |
| MORF4L2 | mortality factor 4 like 2 | -0.0264298 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0262636 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0261514 |
| PTGES2 | prostaglandin E synthase 2 | -0.0261153 |
| ATXN1 | ataxin 1 | -0.0259719 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0258384 |
| MT2A | metallothionein 2A | -0.0258105 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0256049 |
| GLIS3 | GLIS family zinc finger 3 | -0.0253228 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0251761 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0244264 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0243217 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0243215 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0241498 |
| INTS6 | integrator complex subunit 6 | -0.0239329 |
| PCNX4 | pecanex 4 | -0.0238911 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0236088 |
| TMEM165 | transmembrane protein 165 | -0.0235567 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0234764 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0234679 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0234615 |
