| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Vemurafenib perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Vemurafenib_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.121477 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0984053 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0866588 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0697831 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0683945 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0625374 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0599403 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0597337 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0569751 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0560597 |
| ATXN1 | ataxin 1 | 0.0560205 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0550971 |
| POTEF | POTE ankyrin domain family, member F | 0.0535283 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0528836 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0513629 |
| PKM | pyruvate kinase, muscle | 0.0512551 |
| INTS6 | integrator complex subunit 6 | 0.0464978 |
| MAP1B | microtubule-associated protein 1B | 0.0462993 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0455361 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0427225 |
| ATP13A3 | ATPase type 13A3 | 0.0419388 |
| GOLGB1 | golgin B1 | 0.0408005 |
| NAV2 | neuron navigator 2 | 0.0405477 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0400911 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0395061 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0389286 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0387578 |
| FLNB | filamin B, beta | 0.0385596 |
| PRKCA | protein kinase C, alpha | 0.038411 |
| MSN | moesin | 0.0381158 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.036875 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0366232 |
| CAPRIN2 | caprin family member 2 | 0.0364351 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0346966 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0346746 |
| DST | dystonin | 0.0345436 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.0342535 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0341188 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0340533 |
| ITGAV | integrin, alpha V | 0.0332715 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0332393 |
| NUP58 | nucleoporin 58 | 0.0331327 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0330683 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0330194 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0322873 |
| ASPH | aspartate beta-hydroxylase | 0.0319073 |
| SON | SON DNA binding protein | 0.0315329 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | 0.0313044 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0307056 |
| VEGFA | vascular endothelial growth factor A | 0.0296196 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0295643 |
| MYOF | myoferlin | 0.0295383 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0291725 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0287085 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0282921 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0282542 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0280347 |
| ANKRD26 | ankyrin repeat domain 26 | 0.0275041 |
| CLIC4 | chloride intracellular channel 4 | 0.0273295 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0271724 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0270009 |
| BRD4 | bromodomain containing 4 | 0.0268702 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0265486 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0264587 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0263865 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0260787 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0260645 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0259464 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0258158 |
| SVIL | supervillin | 0.0255084 |
| RAI14 | retinoic acid induced 14 | 0.0254204 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.0251771 |
| RAD51B | RAD51 paralog B | 0.0250401 |
| RANBP2 | RAN binding protein 2 | 0.0249601 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0245074 |
| MCL1 | myeloid cell leukemia 1 | 0.0242552 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.023929 |
| ACTN1 | actinin, alpha 1 | 0.0239254 |
| ATP11C | ATPase, class VI, type 11C | 0.0238451 |
| SMAD5 | SMAD family member 5 | 0.0237934 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0237053 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0236637 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0235829 |
| PRR16 | proline rich 16 | 0.0235708 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0234643 |
| PGK1 | phosphoglycerate kinase 1 | 0.0231411 |
| AHI1 | Abelson helper integration site 1 | 0.023088 |
| GPC5 | glypican 5 | 0.0230104 |
| CUL5 | cullin 5 | 0.0227663 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0224893 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0224806 |
| EEA1 | early endosome antigen 1 | 0.0222015 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.0221998 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0221372 |
| SLC38A2 | solute carrier family 38, member 2 | 0.022118 |
| ANO6 | anoctamin 6 | 0.021986 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0217637 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0217186 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0216243 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0215822 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.121337 |
| VIM | vimentin | -0.104975 |
| GNAS | GNAS complex locus | -0.0849391 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0678969 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0639871 |
| PTMA | prothymosin, alpha | -0.0626306 |
| GOLGA4 | golgin A4 | -0.0590354 |
| RPL12 | ribosomal protein L12 | -0.0563229 |
| RPLP1 | ribosomal protein, large, P1 | -0.0547057 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0541548 |
| SMYD3 | SET and MYND domain containing 3 | -0.0520188 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0457241 |
| CANX | calnexin | -0.0452819 |
| TMSB10 | thymosin beta 10 | -0.0450122 |
| KIAA1328 | KIAA1328 | -0.0445763 |
| SPAG9 | sperm associated antigen 9 | -0.0442368 |
| SGO2 | shugoshin 2 | -0.0440326 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0423673 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0420229 |
| RSF1 | remodeling and spacing factor 1 | -0.0391716 |
| RPL4 | ribosomal protein L4 | -0.0391285 |
| RPL32 | ribosomal protein L32 | -0.0389643 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0382512 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0371655 |
| MORF4L2 | mortality factor 4 like 2 | -0.0367964 |
| TXNRD1 | thioredoxin reductase 1 | -0.036714 |
| NLK | nemo-like kinase | -0.0364385 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0358374 |
| RPL11 | ribosomal protein L11 | -0.0353893 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0350916 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0348737 |
| RPS23 | ribosomal protein S23 | -0.0348531 |
| TMEM263 | transmembrane protein 263 | -0.0348025 |
| DIAPH3 | diaphanous-related formin 3 | -0.0344322 |
| ECT2 | epithelial cell transforming 2 | -0.0342942 |
| ANLN | anillin, actin binding protein | -0.0342223 |
| S100A9 | S100 calcium binding protein A9 | -0.0338047 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 | -0.0332491 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0328212 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.032148 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0319546 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.031357 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0311951 |
| NCOA6 | nuclear receptor coactivator 6 | -0.0311849 |
| RPLP0 | ribosomal protein, large, P0 | -0.0311653 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0305997 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0304672 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0304409 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0303993 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0301717 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0298834 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0296484 |
| RPS29 | ribosomal protein S29 | -0.0296117 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0295141 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0292529 |
| RACK1 | receptor for activated C kinase 1 | -0.0290182 |
| SERINC1 | serine incorporator 1 | -0.0288893 |
| HJURP | Holliday junction recognition protein | -0.0287574 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0286098 |
| STK4 | serine/threonine kinase 4 | -0.0286043 |
| RPS27A | ribosomal protein S27a | -0.0285926 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | -0.0280851 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0279556 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0278503 |
| TUT4 | terminal uridylyl transferase 4 | -0.0275072 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0273817 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.0272414 |
| FANCI | Fanconi anemia, complementation group I | -0.0272191 |
| TTK | TTK protein kinase | -0.0271425 |
| RPS8 | ribosomal protein S8 | -0.0271114 |
| TPM4 | tropomyosin 4 | -0.0270597 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.0270513 |
| RPS20 | ribosomal protein S20 | -0.0269914 |
| PRR11 | proline rich 11 | -0.0268428 |
| ATXN2 | ataxin 2 | -0.0263604 |
| GOLT1B | golgi transport 1B | -0.0262035 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0261876 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.0261604 |
| USP1 | ubiquitin specific peptidase 1 | -0.0261086 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | -0.0258424 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0258354 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0256237 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0255286 |
| SEPTIN7 | septin 7 | -0.0255213 |
| MKI67 | marker of proliferation Ki-67 | -0.025501 |
| ANXA2 | annexin A2 | -0.025423 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.0254177 |
| LMNA | lamin A/C | -0.0252947 |
| RPS24 | ribosomal protein S24 | -0.025215 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0251515 |
| ZNF721 | zinc finger protein 721 | -0.0250403 |
| CDC5L | cell division cycle 5-like | -0.0249954 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0249065 |
| STIL | SCL/TAL1 interrupting locus | -0.0248628 |
| SPPL3 | signal peptide peptidase like 3 | -0.0248539 |
| RPS21 | ribosomal protein S21 | -0.0248535 |
| GLG1 | golgi glycoprotein 1 | -0.0246412 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0245822 |
| TUBB | tubulin, beta class I | -0.024478 |
| CBFB | core-binding factor, beta subunit | -0.0244555 |
