Ventricular Hypertrophy Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Enlargement of the cardiac ventricular muscle tissue with increase in the width of the wall of the ventricle and loss of elasticity. Ventricular hypertrophy is clinically differentiated into left and right ventricular hypertrophy. (Human Phenotype Ontology, HP_0001714)
External Link https://www.disgenet.org/browser/0/1/0/C0340279
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Genes

59 genes associated with the disease Ventricular Hypertrophy in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACAD9 acyl-CoA dehydrogenase family, member 9
ACE angiotensin I converting enzyme
ACSL1 acyl-CoA synthetase long-chain family member 1
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
APRT adenine phosphoribosyltransferase
ATF3 activating transcription factor 3
BMP10 bone morphogenetic protein 10
BRAF B-Raf proto-oncogene, serine/threonine kinase
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CARD6 caspase recruitment domain family, member 6
CAV1 caveolin 1, caveolae protein, 22kDa
CAVIN1 caveolae associated protein 1
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
DDAH1 dimethylarginine dimethylaminohydrolase 1
EDN1 endothelin 1
FHL1 four and a half LIM domains 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GPR101 G protein-coupled receptor 101
GYG1 glycogenin 1
HLA-C major histocompatibility complex, class I, C
IRF1 interferon regulatory factor 1
LAMP2 lysosomal-associated membrane protein 2
LMNA lamin A/C
MFAP1 microfibrillar-associated protein 1
MYBPC3 myosin binding protein C, cardiac
MYOCD myocardin
NLRP3 NLR family, pyrin domain containing 3
NOD2 nucleotide-binding oligomerization domain containing 2
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae)
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PMM2 phosphomannomutase 2
POMC proopiomelanocortin
PPARG peroxisome proliferator-activated receptor gamma
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
REN renin
RPL5 ribosomal protein L5
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SPP1 secreted phosphoprotein 1
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
SUCNR1 succinate receptor 1
TAS2R13 taste receptor, type 2, member 13
TNNI3 troponin I type 3 (cardiac)
TNNT2 troponin T type 2 (cardiac)
TRIB3 tribbles pseudokinase 3
VCL vinculin
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor