Ventricular hypertrophy_Myocardial tissue_GSE4678 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE4678
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Genes

600 genes differentially expressed during Ventricular hypertrophy_Myocardial tissue_GSE4678 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
HADH hydroxyacyl-CoA dehydrogenase 4.5639
WDR6 WD repeat domain 6 4.40762
CBX3 chromobox homolog 3 4.20079
INTS7 integrator complex subunit 7 3.53954
IMMT inner membrane protein, mitochondrial 3.50124
TRAF3 TNF receptor-associated factor 3 3.41476
GMPR2 guanosine monophosphate reductase 2 3.39108
OLFM1 olfactomedin 1 3.32668
TUBA1B tubulin, alpha 1b 3.30212
CREBZF CREB/ATF bZIP transcription factor 3.16315
DNMT1 DNA (cytosine-5-)-methyltransferase 1 3.02035
MTMR9 myotubularin related protein 9 2.89028
PANX1 pannexin 1 2.84146
CTR9 CTR9, Paf1/RNA polymerase II complex component 2.72496
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 2.70885
MXD4 MAX dimerization protein 4 2.70123
ZFP91 ZFP91 zinc finger protein 2.62182
TXNRD1 thioredoxin reductase 1 2.56853
DUSP3 dual specificity phosphatase 3 2.53434
MMP23B matrix metallopeptidase 23B 2.5241
TGFB3 transforming growth factor, beta 3 2.47588
PELP1 proline, glutamate and leucine rich protein 1 2.47286
MGP matrix Gla protein 2.45857
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 2.44535
INTS3 integrator complex subunit 3 2.37935
ARMCX2 armadillo repeat containing, X-linked 2 2.34018
SNX1 sorting nexin 1 2.33631
PTGER4 prostaglandin E receptor 4 (subtype EP4) 2.3348
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 2.33156
SETD3 SET domain containing 3 2.3128
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae) 2.27532
RMI1 RecQ mediated genome instability 1 2.22808
NMT1 N-myristoyltransferase 1 2.17693
LRRK1 leucine-rich repeat kinase 1 2.17608
ETF1 eukaryotic translation termination factor 1 2.16176
STXBP1 syntaxin binding protein 1 2.15045
CLCN7 chloride channel, voltage-sensitive 7 2.12698
SOX9 SRY (sex determining region Y)-box 9 2.09148
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 2.08997
CRAMP1L Crm, cramped-like (Drosophila) 2.08837
EP400 E1A binding protein p400 2.06441
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 2.05279
ARID5A AT rich interactive domain 5A (MRF1-like) 2.02273
CXCR6 chemokine (C-X-C motif) receptor 6 2.00855
UBE4B ubiquitination factor E4B 2.00605
TBX18 T-box 18 2.005
FBXW2 F-box and WD repeat domain containing 2 1.99728
SETD7 SET domain containing (lysine methyltransferase) 7 1.99456
PPP4R1 protein phosphatase 4, regulatory subunit 1 1.99388
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) 1.99293
PTPN14 protein tyrosine phosphatase, non-receptor type 14 1.99263
PIGK phosphatidylinositol glycan anchor biosynthesis, class K 1.99167
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 1.98845
GPX3 glutathione peroxidase 3 1.98051
EPHB4 EPH receptor B4 1.97763
CGNL1 cingulin-like 1 1.96535
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 1.92385
TRIB3 tribbles pseudokinase 3 1.91052
FBXO36 F-box protein 36 1.90735
WNT3 wingless-type MMTV integration site family, member 3 1.90382
MYOM1 myomesin 1 1.89715
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 1.89381
PI16 peptidase inhibitor 16 1.88697
SESN3 sestrin 3 1.87985
SEPSECS Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase 1.87964
NIP7 NIP7, nucleolar pre-rRNA processing protein 1.85171
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) 1.83035
HIP1 huntingtin interacting protein 1 1.82366
PMP22 peripheral myelin protein 22 1.7788
EIF4B eukaryotic translation initiation factor 4B 1.76965
FADS1 fatty acid desaturase 1 1.76892
EDN3 endothelin 3 1.75491
TBC1D13 TBC1 domain family, member 13 1.74216
TRIM26 tripartite motif containing 26 1.71339
SHE Src homology 2 domain containing E 1.70888
DUSP16 dual specificity phosphatase 16 1.70502
G6PD glucose-6-phosphate dehydrogenase 1.69706
FEM1B fem-1 homolog b (C. elegans) 1.68428
SLTM SAFB-like, transcription modulator 1.6781
UBE2I ubiquitin-conjugating enzyme E2I 1.67231
CPT1A carnitine palmitoyltransferase 1A (liver) 1.67136
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1.6555
ADORA1 adenosine A1 receptor 1.65432
PPIA peptidylprolyl isomerase A (cyclophilin A) 1.65174
ORC6 origin recognition complex, subunit 6 1.65021
RGS19 regulator of G-protein signaling 19 1.64169
SKI SKI proto-oncogene 1.64067
GPSM3 G-protein signaling modulator 3 1.63989
MCM3AP minichromosome maintenance complex component 3 associated protein 1.63601
DVL1 dishevelled segment polarity protein 1 1.63598
CRYZL1 crystallin, zeta (quinone reductase)-like 1 1.63421
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.63291
ENDOD1 endonuclease domain containing 1 1.63253
UBN1 ubinuclein 1 1.62671
PLXDC2 plexin domain containing 2 1.62262
FSTL3 follistatin-like 3 (secreted glycoprotein) 1.6182
CCDC136 coiled-coil domain containing 136 1.61302
PHOX2A paired-like homeobox 2a 1.61169
MFSD1 major facilitator superfamily domain containing 1 1.59451
TP53INP2 tumor protein p53 inducible nuclear protein 2 1.59277
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 1.59243
EGFL8 EGF-like-domain, multiple 8 1.58315
FUCA1 fucosidase, alpha-L- 1, tissue 1.58277
TSPAN14 tetraspanin 14 1.57249
UBE3C ubiquitin protein ligase E3C 1.57001
CTNND1 catenin (cadherin-associated protein), delta 1 1.56594
AXL AXL receptor tyrosine kinase 1.56376
ZC3H10 zinc finger CCCH-type containing 10 1.56167
RING1 ring finger protein 1 1.55742
RAI14 retinoic acid induced 14 1.552
RAD51AP1 RAD51 associated protein 1 1.54028
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) 1.5384
POC5 POC5 centriolar protein 1.53425
RAMP3 receptor (G protein-coupled) activity modifying protein 3 1.5342
ASXL1 additional sex combs like transcriptional regulator 1 1.53402
RGL1 ral guanine nucleotide dissociation stimulator-like 1 1.5328
UBR4 ubiquitin protein ligase E3 component n-recognin 4 1.52979
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 1.51333
RPL10 ribosomal protein L10 1.51062
STK10 serine/threonine kinase 10 1.50954
MEPCE methylphosphate capping enzyme 1.503
GNG11 guanine nucleotide binding protein (G protein), gamma 11 1.50021
SNAI1 snail family zinc finger 1 1.49967
PAQR4 progestin and adipoQ receptor family member IV 1.49636
PEAR1 platelet endothelial aggregation receptor 1 1.49171
ACP1 acid phosphatase 1, soluble 1.48456
BET1L Bet1 golgi vesicular membrane trafficking protein-like 1.48311
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 1.48281
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 1.48186
ELOVL1 ELOVL fatty acid elongase 1 1.48094
IDI1 isopentenyl-diphosphate delta isomerase 1 1.46359
NUBP1 nucleotide binding protein 1 1.4595
CLK2 CDC-like kinase 2 1.45607
NUMB numb homolog (Drosophila) 1.45539
ANXA7 annexin A7 1.45413
SRPX2 sushi-repeat containing protein, X-linked 2 1.44252
YLPM1 YLP motif containing 1 1.43391
ZNF346 zinc finger protein 346 1.4288
CLDN9 claudin 9 1.42378
RASGRP4 RAS guanyl releasing protein 4 1.42156
SART3 squamous cell carcinoma antigen recognized by T cells 3 1.41744
INTS6 integrator complex subunit 6 1.41707
NPR3 natriuretic peptide receptor 3 1.40756
RABEP1 rabaptin, RAB GTPase binding effector protein 1 1.4024
PARN poly(A)-specific ribonuclease 1.40105
USP39 ubiquitin specific peptidase 39 1.40047
HEXIM1 hexamethylene bis-acetamide inducible 1 1.39273
SRSF6 serine/arginine-rich splicing factor 6 1.39065
FAM89A family with sequence similarity 89, member A 1.39047
PYCARD PYD and CARD domain containing 1.38662
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 1.38157
TARS threonyl-tRNA synthetase 1.37919
USP19 ubiquitin specific peptidase 19 1.37788
ZCCHC8 zinc finger, CCHC domain containing 8 1.37703
CRTAP cartilage associated protein 1.37679
BCAN brevican 1.37382
TMEM183A transmembrane protein 183A 1.37192
WBP5 WW domain binding protein 5 1.36804
MRGPRF MAS-related GPR, member F 1.36465
DAO D-amino-acid oxidase 1.36287
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 1.36065
COG1 component of oligomeric golgi complex 1 1.35754
ACTG1 actin gamma 1 1.35545
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) 1.34925
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 1.34168
GLB1 galactosidase, beta 1 1.34131
GLTP glycolipid transfer protein 1.33896
CDK8 cyclin-dependent kinase 8 1.33366
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 1.33183
ACSL5 acyl-CoA synthetase long-chain family member 5 1.33158
IGFBP5 insulin-like growth factor binding protein 5 1.33072
PPP1R18 protein phosphatase 1, regulatory subunit 18 1.3298
AAGAB alpha- and gamma-adaptin binding protein 1.32587
GPATCH4 G patch domain containing 4 1.32462
OXSR1 oxidative stress responsive 1 1.32282
UBE2L6 ubiquitin-conjugating enzyme E2L 6 1.32217
GHR growth hormone receptor 1.32084
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 1.31784
SERGEF secretion regulating guanine nucleotide exchange factor 1.31426
CTSZ cathepsin Z 1.31232
KIAA0020 KIAA0020 1.30634
PARP2 poly (ADP-ribose) polymerase 2 1.29316
ABI1 abl-interactor 1 1.2884
PLA2G1B phospholipase A2, group IB (pancreas) 1.28777
CGREF1 cell growth regulator with EF-hand domain 1 1.2832
FAM129B family with sequence similarity 129, member B 1.2812
STK32C serine/threonine kinase 32C 1.27552
ZBTB22 zinc finger and BTB domain containing 22 1.27532
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.27293
ZNF790 zinc finger protein 790 1.27245
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 1.2718
PRAF2 PRA1 domain family, member 2 1.27119
STAMBPL1 STAM binding protein-like 1 1.26642
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 1.2648
SULF2 sulfatase 2 1.26415
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 1.26163
SCUBE2 signal peptide, CUB domain, EGF-like 2 1.2545
VKORC1 vitamin K epoxide reductase complex, subunit 1 1.25186
TRIL TLR4 interactor with leucine-rich repeats 1.25133
GIMAP1 GTPase, IMAP family member 1 1.25076
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma 1.24968
FRZB frizzled-related protein 1.24961
CCDC23 coiled-coil domain containing 23 1.2464
EIF5B eukaryotic translation initiation factor 5B 1.24523
APCDD1 adenomatosis polyposis coli down-regulated 1 1.2432
S100A13 S100 calcium binding protein A13 1.24295
RC3H2 ring finger and CCCH-type domains 2 1.24082
CLTC clathrin, heavy chain (Hc) 1.23484
TULP4 tubby like protein 4 1.23096
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.23091
DDX26B DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B 1.22968
PCDHB7 protocadherin beta 7 1.22714
LAMP1 lysosomal-associated membrane protein 1 1.22626
FAP fibroblast activation protein, alpha 1.22604
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa 1.22115
MELK maternal embryonic leucine zipper kinase 1.21935
ERF Ets2 repressor factor 1.2192
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 1.21256
PBX2 pre-B-cell leukemia homeobox 2 1.21156
ARHGAP18 Rho GTPase activating protein 18 1.20998
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 1.20969
ELP2 elongator acetyltransferase complex subunit 2 1.20953
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase 1.20864
PTN pleiotrophin 1.20786
S100A4 S100 calcium binding protein A4 1.20721
ENSA endosulfine alpha 1.20489
RCAN3 RCAN family member 3 1.20406
CRLF1 cytokine receptor-like factor 1 1.2018
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 1.18997
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 1.18891
FAM149B1 family with sequence similarity 149, member B1 1.18864
RHOU ras homolog family member U 1.18732
RBM28 RNA binding motif protein 28 1.18127
CORO1C coronin, actin binding protein, 1C 1.1799
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 1.17842
PIGS phosphatidylinositol glycan anchor biosynthesis, class S 1.17799
SNTG2 syntrophin, gamma 2 1.17707
MCM2 minichromosome maintenance complex component 2 1.17647
TMEM158 transmembrane protein 158 (gene/pseudogene) 1.17502
RPF2 ribosome production factor 2 homolog (S. cerevisiae) 1.17485
DLG5 discs, large homolog 5 (Drosophila) 1.17432
AP1G2 adaptor-related protein complex 1, gamma 2 subunit 1.17391
NARS asparaginyl-tRNA synthetase 1.16832
RPL4 ribosomal protein L4 1.16348
LMNA lamin A/C 1.16343
TRIM27 tripartite motif containing 27 1.16275
MPG N-methylpurine-DNA glycosylase 1.16226
COL14A1 collagen, type XIV, alpha 1 1.16027
FCGBP Fc fragment of IgG binding protein 1.15848
STK38 serine/threonine kinase 38 1.15704
INTS8 integrator complex subunit 8 1.15628
RARS arginyl-tRNA synthetase 1.15566
TRIP12 thyroid hormone receptor interactor 12 1.15483
RAD54L2 RAD54-like 2 (S. cerevisiae) 1.15329
RLIM ring finger protein, LIM domain interacting 1.152
CACNB1 calcium channel, voltage-dependent, beta 1 subunit 1.15092
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 1.14996
CHGA chromogranin A 1.14964
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.14924
EGFR epidermal growth factor receptor 1.14849
SHKBP1 SH3KBP1 binding protein 1 1.14798
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.14542
GAS6 growth arrest-specific 6 1.14484
CCNL2 cyclin L2 1.14113
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 1.13789
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 1.1355
POLE4 polymerase (DNA-directed), epsilon 4, accessory subunit 1.13517
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 1.12948
RUNX3 runt-related transcription factor 3 1.12905
ABHD4 abhydrolase domain containing 4 1.12497
TTC13 tetratricopeptide repeat domain 13 1.12423
SFI1 Sfi1 homolog, spindle assembly associated (yeast) 1.1223
HOXC9 homeobox C9 1.122
PUS7 pseudouridylate synthase 7 (putative) 1.12024
PROCR protein C receptor, endothelial 1.12022
CBFB core-binding factor, beta subunit 1.11631
TMEM45A transmembrane protein 45A 1.11626
FADD Fas (TNFRSF6)-associated via death domain 1.11211
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 1.11135
GBA glucosidase, beta, acid 1.11003
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.10723
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 1.10721
ZNF18 zinc finger protein 18 1.10553
TMEM68 transmembrane protein 68 1.10489
PEA15 phosphoprotein enriched in astrocytes 15 1.10297
RPL13A ribosomal protein L13a 1.10223
RCN1 reticulocalbin 1, EF-hand calcium binding domain 1.09915
COL11A2 collagen, type XI, alpha 2 1.09273
BID BH3 interacting domain death agonist 1.08854
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.08837
RAB34 RAB34, member RAS oncogene family 1.08801
MYBPC3 myosin binding protein C, cardiac 1.08735
PACS2 phosphofurin acidic cluster sorting protein 2 1.08283
PLK2 polo-like kinase 2 1.08155
NSG1 neuron specific gene family member 1 1.08139
TNIP1 TNFAIP3 interacting protein 1 1.07655
PLAGL2 pleiomorphic adenoma gene-like 2 1.07435
ASTN2 astrotactin 2 1.07177
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 1.0703
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 1.06567

decreased expression

Symbol Name Standardized Value
SLAIN2 SLAIN motif family, member 2 -4.66657
CDV3 CDV3 homolog (mouse) -4.44359
LUM lumican -4.44199
CLIP1 CAP-GLY domain containing linker protein 1 -3.94536
CALU calumenin -3.82259
SYNJ2 synaptojanin 2 -3.77742
MFSD4 major facilitator superfamily domain containing 4 -3.66302
DENND5A DENN/MADD domain containing 5A -3.50409
MOBP myelin-associated oligodendrocyte basic protein -3.45614
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 -3.19728
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa -3.06478
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -3.0397
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d -3.03
SPATA19 spermatogenesis associated 19 -3.01782
RAB40B RAB40B, member RAS oncogene family -3.0033
RNF114 ring finger protein 114 -2.93761
MRPL15 mitochondrial ribosomal protein L15 -2.93331
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) -2.92561
HK1 hexokinase 1 -2.88804
PYY peptide YY -2.87727
MYH7 myosin, heavy chain 7, cardiac muscle, beta -2.8739
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A -2.85717
SCAMP1 secretory carrier membrane protein 1 -2.70877
LDAH lipid droplet associated hydrolase -2.68964
OSBPL6 oxysterol binding protein-like 6 -2.68728
SRRM4 serine/arginine repetitive matrix 4 -2.63686
RIMS2 regulating synaptic membrane exocytosis 2 -2.61852
BPIFB1 BPI fold containing family B, member 1 -2.58669
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 -2.54558
SMAD3 SMAD family member 3 -2.4332
MMP2 matrix metallopeptidase 2 -2.38141
CRADD CASP2 and RIPK1 domain containing adaptor with death domain -2.38077
NDRG4 NDRG family member 4 -2.36693
MRPL1 mitochondrial ribosomal protein L1 -2.34507
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.2843
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -2.28359
EN1 engrailed homeobox 1 -2.27851
NPPA natriuretic peptide A -2.2698
RTBDN retbindin -2.24945
CHMP4C charged multivesicular body protein 4C -2.24884
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2 -2.19747
LPCAT3 lysophosphatidylcholine acyltransferase 3 -2.18581
IL15RA interleukin 15 receptor, alpha -2.1774
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A -2.17051
HEATR5B HEAT repeat containing 5B -2.1663
ASB12 ankyrin repeat and SOCS box containing 12 -2.16428
GCA grancalcin, EF-hand calcium binding protein -2.15611
SAAL1 serum amyloid A-like 1 -2.14794
SCAF11 SR-related CTD-associated factor 11 -2.10807
RERG RAS-like, estrogen-regulated, growth inhibitor -2.08651
STAU2 staufen double-stranded RNA binding protein 2 -2.05678
MSL3 male-specific lethal 3 homolog (Drosophila) -2.05086
ASB8 ankyrin repeat and SOCS box containing 8 -2.03927
CA10 carbonic anhydrase X -2.02558
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -1.96122
PNPT1 polyribonucleotide nucleotidyltransferase 1 -1.95266
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow -1.94746
GRTP1 growth hormone regulated TBC protein 1 -1.94641
TMEM129 transmembrane protein 129, E3 ubiquitin protein ligase -1.92622
RREB1 ras responsive element binding protein 1 -1.91544
GLYCTK glycerate kinase -1.91342
PPA2 pyrophosphatase (inorganic) 2 -1.90311
HLTF helicase-like transcription factor -1.90132
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -1.89225
WBP4 WW domain binding protein 4 -1.85574
ZNF189 zinc finger protein 189 -1.8371
CSF3R colony stimulating factor 3 receptor (granulocyte) -1.83212
MRPL42 mitochondrial ribosomal protein L42 -1.83037
PITHD1 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1 -1.8215
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa -1.81121
HDAC9 histone deacetylase 9 -1.81116
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -1.78228
PKD2L2 polycystic kidney disease 2-like 2 -1.77616
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 -1.76481
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) -1.75839
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) -1.75367
BPHL biphenyl hydrolase-like (serine hydrolase) -1.73984
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) -1.72872
MED26 mediator complex subunit 26 -1.72224
CD48 CD48 molecule -1.69207
COL1A2 collagen, type I, alpha 2 -1.68318
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 -1.6816
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 -1.68032
THNSL1 threonine synthase-like 1 (S. cerevisiae) -1.66617
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -1.65655
CLEC4A C-type lectin domain family 4, member A -1.63304
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial -1.63018
LTA lymphotoxin alpha -1.62778
SPRYD4 SPRY domain containing 4 -1.62712
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) -1.61449
PHF2 PHD finger protein 2 -1.61191
WNT8A wingless-type MMTV integration site family, member 8A -1.60427
KRTCAP3 keratinocyte associated protein 3 -1.60097
GFRA3 GDNF family receptor alpha 3 -1.58907
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -1.57036
SIX4 SIX homeobox 4 -1.57023
CATSPER2 cation channel, sperm associated 2 -1.56414
CTC1 CTS telomere maintenance complex component 1 -1.55614
TTC19 tetratricopeptide repeat domain 19 -1.55053
ANGPT1 angiopoietin 1 -1.54878
SCRT1 scratch family zinc finger 1 -1.53568
MDP1 magnesium-dependent phosphatase 1 -1.53164
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -1.5294
MTCH2 mitochondrial carrier 2 -1.52423
FJX1 four jointed box 1 (Drosophila) -1.52382
HMP19 HMP19 protein -1.51916
CPA1 carboxypeptidase A1 (pancreatic) -1.51147
SLMAP sarcolemma associated protein -1.51117
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -1.5073
ZNF143 zinc finger protein 143 -1.50715
TPSG1 tryptase gamma 1 -1.48317
ALOXE3 arachidonate lipoxygenase 3 -1.48234
FAM122A family with sequence similarity 122A -1.4645
C4ORF19 chromosome 4 open reading frame 19 -1.46274
TLX2 T-cell leukemia homeobox 2 -1.4443
SQRDL sulfide quinone reductase-like (yeast) -1.44373
UBE2K ubiquitin-conjugating enzyme E2K -1.42965
UTF1 undifferentiated embryonic cell transcription factor 1 -1.42487
CCR4 chemokine (C-C motif) receptor 4 -1.42253
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A -1.41969
RBKS ribokinase -1.41011
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -1.39331
NUP98 nucleoporin 98kDa -1.39051
CRHR1 corticotropin releasing hormone receptor 1 -1.38966
AK4 adenylate kinase 4 -1.38437
RPP40 ribonuclease P/MRP 40kDa subunit -1.38289
MIF4GD MIF4G domain containing -1.3778
HMX3 H6 family homeobox 3 -1.37369
C16ORF70 chromosome 16 open reading frame 70 -1.37153
MSN moesin -1.36497
TMEM27 transmembrane protein 27 -1.36398
GRPEL2 GrpE-like 2, mitochondrial (E. coli) -1.35948
C5AR1 complement component 5a receptor 1 -1.35745
BROX BRO1 domain and CAAX motif containing -1.3536
SOX5 SRY (sex determining region Y)-box 5 -1.35255
MTOR mechanistic target of rapamycin (serine/threonine kinase) -1.35036
NEUROG1 neurogenin 1 -1.34978
KLK3 kallikrein-related peptidase 3 -1.34583
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain -1.34084
VDAC2 voltage-dependent anion channel 2 -1.34032
AGBL3 ATP/GTP binding protein-like 3 -1.33857
MTA3 metastasis associated 1 family, member 3 -1.33438
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -1.33367
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -1.33032
MARVELD2 MARVEL domain containing 2 -1.31964
EIF3L eukaryotic translation initiation factor 3, subunit L -1.31666
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit -1.31449
CNOT4 CCR4-NOT transcription complex, subunit 4 -1.30659
MRPS2 mitochondrial ribosomal protein S2 -1.30486
ACADL acyl-CoA dehydrogenase, long chain -1.30356
WDR33 WD repeat domain 33 -1.30103
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 -1.29952
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 -1.29421
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -1.29122
SCN4A sodium channel, voltage gated, type IV alpha subunit -1.29032
CES4A carboxylesterase 4A -1.29002
PRSS2 protease, serine, 2 (trypsin 2) -1.28741
FABP1 fatty acid binding protein 1, liver -1.28323
DNAJC19 DnaJ (Hsp40) homolog, subfamily C, member 19 -1.27765
NUP37 nucleoporin 37kDa -1.27109
CLDN1 claudin 1 -1.27059
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) -1.26995
FGD4 FYVE, RhoGEF and PH domain containing 4 -1.26825
MFSD3 major facilitator superfamily domain containing 3 -1.26421
HDAC1 histone deacetylase 1 -1.25986
SYT5 synaptotagmin V -1.2576
GRAMD3 GRAM domain containing 3 -1.25626
SMG8 SMG8 nonsense mediated mRNA decay factor -1.25125
ALAS2 5'-aminolevulinate synthase 2 -1.25109
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 -1.24615
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) -1.23413
LPAR3 lysophosphatidic acid receptor 3 -1.23071
ZNF565 zinc finger protein 565 -1.2205
IL5 interleukin 5 -1.21912
ERC1 ELKS/RAB6-interacting/CAST family member 1 -1.21798
DUT deoxyuridine triphosphatase -1.21729
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -1.21503
C18ORF8 chromosome 18 open reading frame 8 -1.2109
CCDC117 coiled-coil domain containing 117 -1.20854
GPRIN1 G protein regulated inducer of neurite outgrowth 1 -1.20116
IPP intracisternal A particle-promoted polypeptide -1.19937
CKAP5 cytoskeleton associated protein 5 -1.19813
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 -1.19485
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -1.19369
DEPDC1 DEP domain containing 1 -1.19338
ABHD3 abhydrolase domain containing 3 -1.19029
AFMID arylformamidase -1.18762
VAV1 vav 1 guanine nucleotide exchange factor -1.18669
PDCL3 phosducin-like 3 -1.18032
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -1.17856
MTBP MDM2 binding protein -1.17768
PPP6C protein phosphatase 6, catalytic subunit -1.17639
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -1.17515
SDCCAG8 serologically defined colon cancer antigen 8 -1.17411
SLC25A35 solute carrier family 25, member 35 -1.1705
SPIN4 spindlin family, member 4 -1.17037
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 -1.16852
KLF12 Kruppel-like factor 12 -1.16838
MAB21L1 mab-21-like 1 (C. elegans) -1.16762
FOXL1 forkhead box L1 -1.16666
GFOD2 glucose-fructose oxidoreductase domain containing 2 -1.16431
ODF3 outer dense fiber of sperm tails 3 -1.16376
EXTL2 exostosin-like glycosyltransferase 2 -1.15965
BMP6 bone morphogenetic protein 6 -1.15467
GLIS1 GLIS family zinc finger 1 -1.15354
TMEM135 transmembrane protein 135 -1.15278
ACOX1 acyl-CoA oxidase 1, palmitoyl -1.14853
SETDB1 SET domain, bifurcated 1 -1.14613
CNGB3 cyclic nucleotide gated channel beta 3 -1.14202
DRD4 dopamine receptor D4 -1.13443
CDK7 cyclin-dependent kinase 7 -1.13213
FHL2 four and a half LIM domains 2 -1.13161
SCFD1 sec1 family domain containing 1 -1.12848
MRPL3 mitochondrial ribosomal protein L3 -1.12578
WNT6 wingless-type MMTV integration site family, member 6 -1.12267
LSM1 LSM1, U6 small nuclear RNA associated -1.11767
BHLHA15 basic helix-loop-helix family, member a15 -1.11722
ACO2 aconitase 2, mitochondrial -1.11093
ACSBG1 acyl-CoA synthetase bubblegum family member 1 -1.101
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit -1.09956
PTBP2 polypyrimidine tract binding protein 2 -1.09435
PLAGL1 pleiomorphic adenoma gene-like 1 -1.09345
CACNB4 calcium channel, voltage-dependent, beta 4 subunit -1.0915
C12ORF66 chromosome 12 open reading frame 66 -1.09069
AIM1 absent in melanoma 1 -1.08939
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 -1.08937
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) -1.08881
FBXO3 F-box protein 3 -1.08843
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1 -1.08221
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -1.08189
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled -1.07909
ABHD10 abhydrolase domain containing 10 -1.07886
LY6G6C lymphocyte antigen 6 complex, locus G6C -1.07854
FTCD formimidoyltransferase cyclodeaminase -1.07688
DNAJB7 DnaJ (Hsp40) homolog, subfamily B, member 7 -1.07687
CASP6 caspase 6, apoptosis-related cysteine peptidase -1.07499
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type -1.07423
GC group-specific component (vitamin D binding protein) -1.07401
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa -1.06791
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 -1.06532
CATSPER1 cation channel, sperm associated 1 -1.06441
AFP alpha-fetoprotein -1.06112
UPK3B uroplakin 3B -1.05826
FUNDC1 FUN14 domain containing 1 -1.05822
TFAP2D transcription factor AP-2 delta (activating enhancer binding protein 2 delta) -1.05765
FAM114A2 family with sequence similarity 114, member A2 -1.05742
CD36 CD36 molecule (thrombospondin receptor) -1.05435
VDAC1 voltage-dependent anion channel 1 -1.04902
ZNF22 zinc finger protein 22 -1.04831
TIPRL TOR signaling pathway regulator -1.04739
TRAF4 TNF receptor-associated factor 4 -1.04643
CREB1 cAMP responsive element binding protein 1 -1.04554
PRR15 proline rich 15 -1.0439
LRPPRC leucine-rich pentatricopeptide repeat containing -1.0384
PRKX protein kinase, X-linked -1.03799
COG6 component of oligomeric golgi complex 6 -1.03516
FSCN3 fascin actin-bundling protein 3, testicular -1.03409
LOC728392 uncharacterized LOC728392 -1.03407
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A -1.03389
MTO1 mitochondrial tRNA translation optimization 1 -1.03347
ERP44 endoplasmic reticulum protein 44 -1.03107
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 -1.03008
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) -1.02994
GREM1 gremlin 1, DAN family BMP antagonist -1.0291
RHOV ras homolog family member V -1.02886
PEX5 peroxisomal biogenesis factor 5 -1.02812
OMP olfactory marker protein -1.02804
TOR1AIP1 torsin A interacting protein 1 -1.02268
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -1.02233
FGF16 fibroblast growth factor 16 -1.02128
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) -1.01864
PRPS2 phosphoribosyl pyrophosphate synthetase 2 -1.01693
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 -1.0162
ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2 -1.01219
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1 -1.01116
MED14 mediator complex subunit 14 -1.01052
KANSL1 KAT8 regulatory NSL complex subunit 1 -1.00955
TMOD2 tropomodulin 2 (neuronal) -1.00766
SLC31A1 solute carrier family 31 (copper transporter), member 1 -1.00673
SOD2 superoxide dismutase 2, mitochondrial -1.00412
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 -0.994823
PIWIL1 piwi-like RNA-mediated gene silencing 1 -0.98861
NGFR nerve growth factor receptor -0.986685
MRPL35 mitochondrial ribosomal protein L35 -0.986597
GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 -0.981049
SPAG1 sperm associated antigen 1 -0.980021
PPT1 palmitoyl-protein thioesterase 1 -0.977308
CISH cytokine inducible SH2-containing protein -0.977173
CUX2 cut-like homeobox 2 -0.975614
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -0.975015
PHKG1 phosphorylase kinase, gamma 1 (muscle) -0.973703
GK2 glycerol kinase 2 -0.973605
STOM stomatin -0.973294
DMKN dermokine -0.972859
COQ9 coenzyme Q9 -0.96895
NR0B2 nuclear receptor subfamily 0, group B, member 2 -0.965906
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4 -0.959381
MAP2K5 mitogen-activated protein kinase kinase 5 -0.956527
HOXA7 homeobox A7 -0.955865
LIPT1 lipoyltransferase 1 -0.954667
Funding