Verapamil Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine. (Chemical Entities of Biological Interest Ontology, CHEBI_9948)
External Link http://ctdbase.org/detail.go?type=chem&acc=D014700
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Genes

77 genes/proteins interacting with the chemical Verapamil from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACTA2 actin, alpha 2, smooth muscle, aorta
ADRA1A adrenoceptor alpha 1A
ADRA1B adrenoceptor alpha 1B
ADRA1D adrenoceptor alpha 1D
ADRB1 adrenoceptor beta 1
BCL2 B-cell CLL/lymphoma 2
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CALCA calcitonin-related polypeptide alpha
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK4 calcium/calmodulin-dependent protein kinase IV
CASP12 caspase 12 (gene/pseudogene)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CLU clusterin
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DDIT3 DNA-damage-inducible transcript 3
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
GAL galanin/GMAP prepropeptide
GAP43 growth associated protein 43
GFAP glial fibrillary acidic protein
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
LIF leukemia inhibitory factor
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MPO myeloperoxidase
MYBPC3 myosin binding protein C, cardiac
NEFL neurofilament, light polypeptide
NEFM neurofilament, medium polypeptide
NPPA natriuretic peptide A
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PARP1 poly (ADP-ribose) polymerase 1
PF4 platelet factor 4
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRL prolactin
RET ret proto-oncogene
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
STAR steroidogenic acute regulatory protein
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TGFB1 transforming growth factor, beta 1
TIMP1 TIMP metallopeptidase inhibitor 1
TNF tumor necrosis factor
TRH thyrotropin-releasing hormone
TSHB thyroid stimulating hormone, beta
VIM vimentin
ZNRD1 zinc ribbon domain containing 1