Verapamil Gene Set

Dataset HMDB Metabolites of Enzymes
Category physical interactions
Type metabolite
Description A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine. (Chemical Entities of Biological Interest Ontology, CHEBI_9948)
External Link http://www.hmdb.ca/metabolites/HMDB01850
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Genes

18 interacting proteins for the Verapamil metabolite from the curated HMDB Metabolites of Enzymes dataset.

Symbol Name
CA1 carbonic anhydrase I
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
SCN5A sodium channel, voltage gated, type V alpha subunit
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5