| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verapamil perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Verapamil_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.256042 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.187138 |
| MT2A | metallothionein 2A | 0.174485 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.166826 |
| TMSB10 | thymosin beta 10 | 0.159089 |
| PTMA | prothymosin, alpha | 0.142236 |
| B2M | beta-2-microglobulin | 0.129897 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.121042 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.12051 |
| VIM | vimentin | 0.113785 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.108603 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0968108 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0940654 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0922257 |
| PODXL | podocalyxin-like | 0.0895474 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0864281 |
| CSTB | cystatin B (stefin B) | 0.0824741 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0778213 |
| ANXA2 | annexin A2 | 0.0733001 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0629987 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0625331 |
| SQSTM1 | sequestosome 1 | 0.0609891 |
| FTL | ferritin, light polypeptide | 0.0589567 |
| ENO1 | enolase 1, (alpha) | 0.0566425 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0565303 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0553915 |
| S100A10 | S100 calcium binding protein A10 | 0.0512265 |
| LMNA | lamin A/C | 0.0510172 |
| NDRG1 | N-myc downstream regulated 1 | 0.0503999 |
| SETD5 | SET domain containing 5 | 0.0500033 |
| RPS3 | ribosomal protein S3 | 0.0497411 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0491638 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0490382 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0478243 |
| GOLGA4 | golgin A4 | 0.0478103 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0474045 |
| RPL37A | ribosomal protein L37a | 0.045259 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0446124 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0445516 |
| S100A11 | S100 calcium binding protein A11 | 0.043335 |
| ZNF292 | zinc finger protein 292 | 0.0428803 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0419583 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0417696 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0415768 |
| RTN4 | reticulon 4 | 0.04126 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0407276 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0405562 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0400844 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0400795 |
| DST | dystonin | 0.0387557 |
| KLF6 | Kruppel-like factor 6 | 0.0379629 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.037372 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0367631 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0363252 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0361593 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0360806 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0355401 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.0355219 |
| FMNL2 | formin-like 2 | 0.0353767 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0352724 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0351905 |
| HELZ | helicase with zinc finger | 0.0344191 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0341262 |
| ABI1 | abl-interactor 1 | 0.033984 |
| MSI2 | musashi RNA-binding protein 2 | 0.0338344 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0333573 |
| ADM | adrenomedullin | 0.0331151 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0323641 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.031602 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0312294 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0312212 |
| RPL12 | ribosomal protein L12 | 0.0312154 |
| PGK1 | phosphoglycerate kinase 1 | 0.0311153 |
| RPS8 | ribosomal protein S8 | 0.0310605 |
| RNF24 | ring finger protein 24 | 0.0310436 |
| ANXA1 | annexin A1 | 0.0307697 |
| RPS19 | ribosomal protein S19 | 0.030447 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0302301 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.029746 |
| RPS2 | ribosomal protein S2 | 0.029684 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0296815 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0296667 |
| FSTL1 | follistatin-like 1 | 0.0295143 |
| VCL | vinculin | 0.0294985 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0289268 |
| HLA-A | major histocompatibility complex, class I, A | 0.0287254 |
| MB21D2 | Mab-21 domain containing 2 | 0.0284818 |
| RAI1 | retinoic acid induced 1 | 0.0283889 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0283847 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0278682 |
| FOSL1 | FOS-like antigen 1 | 0.0278273 |
| FAM13A | family with sequence similarity 13, member A | 0.027809 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0275404 |
| SEC61G | Sec61 gamma subunit | 0.0273383 |
| STC1 | stanniocalcin 1 | 0.0270203 |
| FAM107B | family with sequence similarity 107, member B | 0.0270059 |
| MYOF | myoferlin | 0.0268389 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0264561 |
| CTBP2 | C-terminal binding protein 2 | 0.026399 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0261727 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LOX | lysyl oxidase | -0.101849 |
| NAV1 | neuron navigator 1 | -0.0888647 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0865138 |
| COL5A1 | collagen, type V, alpha 1 | -0.064317 |
| COL1A2 | collagen, type I, alpha 2 | -0.0482987 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0414805 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0403536 |
| MYADM | myeloid-associated differentiation marker | -0.0381808 |
| GLIS3 | GLIS family zinc finger 3 | -0.0376149 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0369493 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0355993 |
| SUCNR1 | succinate receptor 1 | -0.035436 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0340121 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.032809 |
| TAPBP | TAP binding protein (tapasin) | -0.0315827 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0310251 |
| FBN1 | fibrillin 1 | -0.0292836 |
| RNF213 | ring finger protein 213 | -0.0291655 |
| EXOC6B | exocyst complex component 6B | -0.0290031 |
| CDH13 | cadherin 13 | -0.0279613 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0264145 |
| CCND1 | cyclin D1 | -0.0258251 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0241423 |
| BPTF | bromodomain PHD finger transcription factor | -0.0233265 |
| EGFR | epidermal growth factor receptor | -0.0232992 |
| RASA3 | RAS p21 protein activator 3 | -0.0218635 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0212475 |
| SLFN5 | schlafen family member 5 | -0.0208746 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0206732 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0205955 |
| VEGFA | vascular endothelial growth factor A | -0.0203676 |
| FLNA | filamin A, alpha | -0.0199887 |
| PLSCR1 | phospholipid scramblase 1 | -0.019986 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0199658 |
| LAMA5 | laminin, alpha 5 | -0.0198857 |
| ZNF217 | zinc finger protein 217 | -0.0191202 |
| ANTXR1 | anthrax toxin receptor 1 | -0.018868 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0188237 |
| SLF2 | SMC5-SMC6 complex localization factor 2 | -0.0187895 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0185606 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0184769 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0184416 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0179896 |
| PLAT | plasminogen activator, tissue | -0.0178271 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0176622 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0175639 |
| PLEC | plectin | -0.0173617 |
| THBS2 | thrombospondin 2 | -0.0170254 |
| C1D | C1D nuclear receptor corepressor | -0.016908 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0167951 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0167918 |
| SMAD3 | SMAD family member 3 | -0.0166407 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0166402 |
| EHBP1 | EH domain binding protein 1 | -0.016623 |
| NCOR2 | nuclear receptor corepressor 2 | -0.01648 |
| PXDN | peroxidasin | -0.0164472 |
| CDC16 | cell division cycle 16 | -0.016242 |
| NECTIN3 | nectin cell adhesion molecule 3 | -0.0161904 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | -0.0161281 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | -0.016093 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0160626 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0160243 |
| GSE1 | Gse1 coiled-coil protein | -0.016 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.0159159 |
| TPM1 | tropomyosin 1 (alpha) | -0.0159083 |
| CEP112 | centrosomal protein 112kDa | -0.0158547 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0158308 |
| SMIM44 | small integral membrane protein 44 | -0.0156977 |
| TBCA | tubulin folding cofactor A | -0.0153315 |
| OSMR | oncostatin M receptor | -0.0152007 |
| COL5A2 | collagen, type V, alpha 2 | -0.0151151 |
| MX2 | MX dynamin-like GTPase 2 | -0.0150565 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0150402 |
| FRMD4A | FERM domain containing 4A | -0.0149932 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0149511 |
| RC3H2 | ring finger and CCCH-type domains 2 | -0.0148728 |
| NAV2 | neuron navigator 2 | -0.0148483 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0148057 |
| RNF144A | ring finger protein 144A | -0.0147253 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0146882 |
| TUT7 | terminal uridylyl transferase 7 | -0.0146453 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.014506 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0143872 |
| CCM2 | cerebral cavernous malformation 2 | -0.0143619 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.0143582 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | -0.0142671 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0142458 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.0142206 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0142142 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0142079 |
| NSD1 | nuclear receptor binding SET domain protein 1 | -0.0141245 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0139592 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0138877 |
| ZNF207 | zinc finger protein 207 | -0.0138693 |
| VMP1 | vacuole membrane protein 1 | -0.013779 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0137633 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0136726 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0136535 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0136116 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | -0.0135455 |