| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verapamil perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Verapamil_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0544273 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0328339 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0321632 |
| CADM1 | cell adhesion molecule 1 | 0.0317818 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0317214 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0278328 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0263248 |
| NAV2 | neuron navigator 2 | 0.0240556 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0227856 |
| PRELID2 | PRELI domain containing 2 | 0.021367 |
| CCNL1 | cyclin L1 | 0.0210367 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0199778 |
| ZFP36 | ZFP36 ring finger protein | 0.0198507 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.019715 |
| FOSL1 | FOS-like antigen 1 | 0.0184517 |
| PDE10A | phosphodiesterase 10A | 0.0170137 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0162232 |
| NDRG1 | N-myc downstream regulated 1 | 0.0161488 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0157005 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0148467 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0142749 |
| KAZN | kazrin, periplakin interacting protein | 0.0140698 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0139586 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0136954 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0136529 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0133966 |
| ATP13A3 | ATPase type 13A3 | 0.0132675 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0132434 |
| TMEM39A | transmembrane protein 39A | 0.0125449 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0121086 |
| SPAG9 | sperm associated antigen 9 | 0.0118299 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | 0.0117997 |
| DYM | dymeclin | 0.0116778 |
| RNF145 | ring finger protein 145 | 0.0115383 |
| SESN2 | sestrin 2 | 0.0111232 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0109935 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0109298 |
| RNF220 | ring finger protein 220 | 0.0108706 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0108448 |
| MRTFA | myocardin related transcription factor A | 0.0106296 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0106245 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0105923 |
| KIF13A | kinesin family member 13A | 0.0102934 |
| AGRN | agrin | 0.0101803 |
| YEATS2 | YEATS domain containing 2 | 0.010151 |
| SLMAP | sarcolemma associated protein | 0.0101259 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0101161 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0100498 |
| KIAA1328 | KIAA1328 | 0.0100446 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.00996061 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.00992372 |
| SMYD3 | SET and MYND domain containing 3 | 0.00978112 |
| HDAC9 | histone deacetylase 9 | 0.00973008 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.00967225 |
| HIP1 | huntingtin interacting protein 1 | 0.00953634 |
| SNX3 | sorting nexin 3 | 0.0095192 |
| CDON | cell adhesion associated, oncogene regulated | 0.00951274 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.00941302 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00918482 |
| SUCO | SUN domain containing ossification factor | 0.0090991 |
| BRD4 | bromodomain containing 4 | 0.00901154 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.00900518 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.00898929 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0088685 |
| SNX14 | sorting nexin 14 | 0.00870387 |
| ZMAT4 | zinc finger, matrin-type 4 | 0.00859815 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0085227 |
| YAP1 | Yes-associated protein 1 | 0.00842271 |
| EFNA5 | ephrin-A5 | 0.00837122 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.00835196 |
| TMEM178B | transmembrane protein 178B | 0.00824797 |
| EVI5 | ecotropic viral integration site 5 | 0.00820693 |
| NT5DC3 | 5'-nucleotidase domain containing 3 | 0.00819171 |
| CCDC88A | coiled-coil domain containing 88A | 0.00797489 |
| HM13 | histocompatibility (minor) 13 | 0.0079292 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00781944 |
| FAM193B | family with sequence similarity 193, member B | 0.00781213 |
| PLAUR | plasminogen activator, urokinase receptor | 0.00780159 |
| TXNDC11 | thioredoxin domain containing 11 | 0.0077962 |
| SLC22A23 | solute carrier family 22, member 23 | 0.00771295 |
| CA8 | carbonic anhydrase VIII | 0.00771273 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.00764533 |
| DIAPH3 | diaphanous-related formin 3 | 0.00759725 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.00756923 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.00756865 |
| RNF149 | ring finger protein 149 | 0.00754102 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.00744497 |
| ANKMY2 | ankyrin repeat and MYND domain containing 2 | 0.00743779 |
| GRK5 | G protein-coupled receptor kinase 5 | 0.00738233 |
| CD109 | CD109 molecule | 0.00738085 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | 0.00735442 |
| ADAR | adenosine deaminase, RNA-specific | 0.0073212 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.00730823 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.00729929 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.00728046 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.00726574 |
| IER2 | immediate early response 2 | 0.00726346 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00725566 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.00716096 |
| PGM3 | phosphoglucomutase 3 | 0.00715594 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.299295 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.19787 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.187627 |
| FN1 | fibronectin 1 | -0.187353 |
| COL1A1 | collagen, type I, alpha 1 | -0.177483 |
| COL1A2 | collagen, type I, alpha 2 | -0.13669 |
| COL6A3 | collagen, type VI, alpha 3 | -0.13324 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.129458 |
| CALR | calreticulin | -0.107147 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.080798 |
| TMSB10 | thymosin beta 10 | -0.0780155 |
| STC1 | stanniocalcin 1 | -0.0768792 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0756336 |
| UBC | ubiquitin C | -0.0724724 |
| ENO1 | enolase 1, (alpha) | -0.0700173 |
| FBN1 | fibrillin 1 | -0.0699807 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0699295 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.068035 |
| CD44 | CD44 molecule (Indian blood group) | -0.059614 |
| ASPH | aspartate beta-hydroxylase | -0.0593956 |
| INHBA | inhibin, beta A | -0.0592606 |
| LDHA | lactate dehydrogenase A | -0.0568992 |
| CANX | calnexin | -0.0538993 |
| TPM4 | tropomyosin 4 | -0.0528281 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0520354 |
| AHNAK | AHNAK nucleoprotein | -0.0507609 |
| PTMA | prothymosin, alpha | -0.0504321 |
| RPL35A | ribosomal protein L35a | -0.0495459 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0457549 |
| PKM | pyruvate kinase, muscle | -0.0431423 |
| IER3 | immediate early response 3 | -0.0428246 |
| TMSB4X | thymosin beta 4, X-linked | -0.0418229 |
| ACTG1 | actin gamma 1 | -0.041644 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0408446 |
| CALU | calumenin | -0.0408412 |
| RPS8 | ribosomal protein S8 | -0.0402761 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0394682 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.039233 |
| RPL26 | ribosomal protein L26 | -0.0389254 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0384862 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0362952 |
| COL5A1 | collagen, type V, alpha 1 | -0.0359518 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0358965 |
| HMGA2 | high mobility group AT-hook 2 | -0.0358245 |
| HLA-B | major histocompatibility complex, class I, B | -0.0356463 |
| S100A6 | S100 calcium binding protein A6 | -0.0349091 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0348787 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0348333 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0347604 |
| RPL23 | ribosomal protein L23 | -0.0339861 |
| YBX1 | Y box binding protein 1 | -0.0332499 |
| RPS27A | ribosomal protein S27a | -0.0331974 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0327113 |
| MT1X | metallothionein 1X | -0.0326427 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0317457 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0316997 |
| IL6 | interleukin 6 | -0.0309724 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0292793 |
| MT2A | metallothionein 2A | -0.0291595 |
| CDH13 | cadherin 13 | -0.0291504 |
| HDLBP | high density lipoprotein binding protein | -0.0291087 |
| VEGFA | vascular endothelial growth factor A | -0.029061 |
| LOX | lysyl oxidase | -0.0290454 |
| PLEC | plectin | -0.0290061 |
| S100A9 | S100 calcium binding protein A9 | -0.0288627 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.028601 |
| VCAN | versican | -0.028538 |
| S100A10 | S100 calcium binding protein A10 | -0.0283132 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0281368 |
| RPS6 | ribosomal protein S6 | -0.0279603 |
| RPL12 | ribosomal protein L12 | -0.0275899 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0274175 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.027226 |
| FTL | ferritin, light polypeptide | -0.0271146 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0270647 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0266674 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0259484 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0258696 |
| CTSB | cathepsin B | -0.0258631 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0256369 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0256227 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0256025 |
| RPL8 | ribosomal protein L8 | -0.0254579 |
| RPL5 | ribosomal protein L5 | -0.0253104 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0251583 |
| RPL11 | ribosomal protein L11 | -0.0238128 |
| RPS20 | ribosomal protein S20 | -0.0237627 |
| RPLP1 | ribosomal protein, large, P1 | -0.023515 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0231296 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0231215 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0227849 |
| RPS24 | ribosomal protein S24 | -0.022729 |
| LMNA | lamin A/C | -0.0225434 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0223894 |
| LOXL2 | lysyl oxidase-like 2 | -0.0223151 |
| RPS13 | ribosomal protein S13 | -0.0223111 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0221522 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0221228 |
| B2M | beta-2-microglobulin | -0.0219485 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0218725 |
