| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verapamil perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Verapamil_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.256313 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.173937 |
| FNDC3B | fibronectin type III domain containing 3B | 0.156033 |
| ENO1 | enolase 1, (alpha) | 0.11744 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.104811 |
| DSPP | dentin sialophosphoprotein | 0.0992977 |
| APOB | apolipoprotein B | 0.0934945 |
| C3 | complement component 3 | 0.0928954 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.091352 |
| TF | transferrin | 0.0911357 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0847756 |
| DTNA | dystrobrevin, alpha | 0.0803717 |
| AFDN | afadin, adherens junction formation factor | 0.0780213 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0767189 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0738739 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0699546 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0687129 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0628251 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0609257 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0602241 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0571113 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0540178 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0524678 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0524654 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0488643 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0480674 |
| ZNF292 | zinc finger protein 292 | 0.0479946 |
| FMNL2 | formin-like 2 | 0.0466545 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0450713 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.044933 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.044911 |
| QKI | QKI, KH domain containing, RNA binding | 0.0448102 |
| ASPH | aspartate beta-hydroxylase | 0.0444367 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0440004 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0432316 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0419971 |
| DST | dystonin | 0.0419726 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0415726 |
| PLIN2 | perilipin 2 | 0.0415169 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0414766 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.04048 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0399938 |
| PRELID2 | PRELI domain containing 2 | 0.039622 |
| HELZ | helicase with zinc finger | 0.0392872 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.039163 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0388765 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0386997 |
| RPS3 | ribosomal protein S3 | 0.0376149 |
| MYO1B | myosin IB | 0.0368329 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0368188 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0365671 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0364068 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.036081 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.0355316 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.035243 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0347756 |
| PHYHIPL | phytanoyl-CoA 2-hydroxylase interacting protein-like | 0.0347309 |
| FAM13A | family with sequence similarity 13, member A | 0.0344447 |
| KIAA1217 | KIAA1217 | 0.0343303 |
| WWC2 | WW and C2 domain containing 2 | 0.0338238 |
| H1-0 | H1.0 linker histone | 0.0337947 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0329537 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0324211 |
| USP47 | ubiquitin specific peptidase 47 | 0.0320926 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0318714 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.0317335 |
| CALD1 | caldesmon 1 | 0.0312631 |
| TOP1 | topoisomerase (DNA) I | 0.0312335 |
| INSIG2 | insulin induced gene 2 | 0.0312215 |
| KIF1B | kinesin family member 1B | 0.030966 |
| NBAS | neuroblastoma amplified sequence | 0.0305553 |
| CDK19 | cyclin-dependent kinase 19 | 0.030439 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0303725 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0302094 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0289822 |
| PHF3 | PHD finger protein 3 | 0.0289797 |
| LRRC1 | leucine rich repeat containing 1 | 0.0288486 |
| MALT1 | MALT1 paracaspase | 0.0287546 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0285841 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0284194 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0279809 |
| RPS2 | ribosomal protein S2 | 0.0276672 |
| PTK2 | protein tyrosine kinase 2 | 0.0276596 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0272766 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.027044 |
| RPL3 | ribosomal protein L3 | 0.0269756 |
| CDK8 | cyclin-dependent kinase 8 | 0.0269378 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0267598 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0266922 |
| ABAT | 4-aminobutyrate aminotransferase | 0.0262707 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0262427 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0261764 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0261516 |
| TRIM26 | tripartite motif containing 26 | 0.0261029 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0260046 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0259467 |
| SYBU | syntabulin (syntaxin-interacting) | 0.0259467 |
| MALRD1 | MAM and LDL receptor class A domain containing 1 | 0.0259282 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0258883 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0256152 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.25979 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.112486 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0935259 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.084583 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0744758 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0655195 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0634318 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0602306 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.051198 |
| RPS6 | ribosomal protein S6 | -0.0484839 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0460475 |
| EGR1 | early growth response 1 | -0.0460251 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0442045 |
| RPL38 | ribosomal protein L38 | -0.0434913 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0429636 |
| APOA2 | apolipoprotein A-II | -0.0429412 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.042187 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0417964 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.0416655 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0411635 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0405114 |
| A2M | alpha-2-macroglobulin | -0.0384059 |
| RPL23 | ribosomal protein L23 | -0.0376456 |
| FOXP1 | forkhead box P1 | -0.0369021 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0354711 |
| MT2A | metallothionein 2A | -0.0341589 |
| TMSB10 | thymosin beta 10 | -0.0340415 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0329739 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.032868 |
| RPS4X | ribosomal protein S4, X-linked | -0.0324188 |
| LDHA | lactate dehydrogenase A | -0.032064 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.031301 |
| MCL1 | myeloid cell leukemia 1 | -0.0306983 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0306936 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0306143 |
| PEG3 | paternally expressed 3 | -0.0296398 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0292552 |
| RPLP0 | ribosomal protein, large, P0 | -0.029138 |
| RPL28 | ribosomal protein L28 | -0.0289927 |
| RPL34 | ribosomal protein L34 | -0.0287372 |
| RPL35A | ribosomal protein L35a | -0.0286498 |
| HMGA1 | high mobility group AT-hook 1 | -0.0276089 |
| RBM25 | RNA binding motif protein 25 | -0.027326 |
| RNF213 | ring finger protein 213 | -0.0271777 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0271552 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.0270986 |
| MT1X | metallothionein 1X | -0.0270262 |
| TAPBP | TAP binding protein (tapasin) | -0.026839 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.0265777 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0261742 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.026075 |
| RPLP1 | ribosomal protein, large, P1 | -0.0258812 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0253861 |
| SMYD3 | SET and MYND domain containing 3 | -0.025386 |
| GSE1 | Gse1 coiled-coil protein | -0.025227 |
| UBC | ubiquitin C | -0.0245729 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0244891 |
| LCN2 | lipocalin 2 | -0.0243398 |
| AHSG | alpha-2-HS-glycoprotein | -0.0241892 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0241682 |
| RPS27A | ribosomal protein S27a | -0.0239695 |
| IL32 | interleukin 32 | -0.0238478 |
| CFB | complement factor B | -0.0234432 |
| AK1 | adenylate kinase 1 | -0.0233806 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0227631 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.0225653 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0225367 |
| BSG | basigin (Ok blood group) | -0.0223921 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.0222888 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0222432 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0221616 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0221435 |
| UBB | ubiquitin B | -0.0215505 |
| SMAD3 | SMAD family member 3 | -0.021494 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0212988 |
| RPS5 | ribosomal protein S5 | -0.0212915 |
| B2M | beta-2-microglobulin | -0.0212641 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0212138 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.02112 |
| ECE1 | endothelin converting enzyme 1 | -0.0210292 |
| ZNF207 | zinc finger protein 207 | -0.0209061 |
| RPL5 | ribosomal protein L5 | -0.0209041 |
| BRD2 | bromodomain containing 2 | -0.0208889 |
| FTL | ferritin, light polypeptide | -0.0208688 |
| EPHA2 | EPH receptor A2 | -0.0207052 |
| SKIL | SKI-like proto-oncogene | -0.0206812 |
| HLA-B | major histocompatibility complex, class I, B | -0.0204832 |
| RPL31 | ribosomal protein L31 | -0.0204648 |
| RPL37 | ribosomal protein L37 | -0.0203994 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0202458 |
| BCL2L1 | BCL2-like 1 | -0.0201518 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | -0.0201195 |
| POTEF | POTE ankyrin domain family, member F | -0.0200442 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | -0.0200263 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0200094 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0199517 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0198198 |
| USP34 | ubiquitin specific peptidase 34 | -0.0197975 |
| PHF14 | PHD finger protein 14 | -0.0194008 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0193606 |
