Verapamil_Hs 766T Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Verapamil perturbation in Hs 766T cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Verapamil_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
TIMP3 TIMP metallopeptidase inhibitor 3 0.188615
PODXL podocalyxin-like 0.18517
PTMA prothymosin, alpha 0.126603
H1-0 H1.0 linker histone 0.120073
ENO1 enolase 1, (alpha) 0.103495
FLNB filamin B, beta 0.102681
RPS3 ribosomal protein S3 0.0994552
TRIO trio Rho guanine nucleotide exchange factor 0.09536
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.0948296
MEF2A myocyte enhancer factor 2A 0.0942547
PGK1 phosphoglycerate kinase 1 0.0848421
MTSS1 metastasis suppressor 1 0.0810208
B2M beta-2-microglobulin 0.0752048
SLC35F3 solute carrier family 35, member F3 0.0724365
STC1 stanniocalcin 1 0.0683653
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.0666348
MYOF myoferlin 0.0665882
CD44 CD44 molecule (Indian blood group) 0.0654642
KCNK1 potassium channel, two pore domain subfamily K, member 1 0.0652497
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.0644469
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0634449
RPS2 ribosomal protein S2 0.062267
RPS8 ribosomal protein S8 0.0614921
RPS12 ribosomal protein S12 0.0607619
EMP1 epithelial membrane protein 1 0.0601417
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0591422
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 0.058311
KRT17 keratin 17, type I 0.0579984
ANXA2 annexin A2 0.0568395
NAMPT nicotinamide phosphoribosyltransferase 0.0561247
MT2A metallothionein 2A 0.0541251
PDE4D phosphodiesterase 4D, cAMP-specific 0.0506534
MACF1 microtubule-actin crosslinking factor 1 0.0501423
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0498662
RPS6 ribosomal protein S6 0.049407
FOXO1 forkhead box O1 0.0477555
CAV1 caveolin 1, caveolae protein, 22kDa 0.047289
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.0464411
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0450131
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.0439067
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0438169
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.0437051
DUSP6 dual specificity phosphatase 6 0.0414917
FNIP1 folliculin interacting protein 1 0.040694
RACK1 receptor for activated C kinase 1 0.0404318
RPL4 ribosomal protein L4 0.0401934
RPL12 ribosomal protein L12 0.0401671
FOSL1 FOS-like antigen 1 0.0401471
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0399998
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 0.0388849
VCL vinculin 0.0388831
ASPH aspartate beta-hydroxylase 0.0386671
ESYT2 extended synaptotagmin-like protein 2 0.0378764
ANLN anillin, actin binding protein 0.037275
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.036901
TGM2 transglutaminase 2 0.0368268
FAM13A family with sequence similarity 13, member A 0.0364823
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0364254
FHIP1A FHF complex subunit HOOK interacting protein 1A 0.0361905
CAVIN1 caveolae associated protein 1 0.0361036
MXI1 MAX interactor 1, dimerization protein 0.0358193
MKI67 marker of proliferation Ki-67 0.0355723
RPS19 ribosomal protein S19 0.0353147
SQLE squalene epoxidase 0.0349099
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.0348739
PDK3 pyruvate dehydrogenase kinase, isozyme 3 0.0348297
SQSTM1 sequestosome 1 0.0338066
TM4SF1 transmembrane 4 L six family member 1 0.0337463
KRT14 keratin 14, type I 0.0336491
AKAP13 A kinase (PRKA) anchor protein 13 0.0331628
FSCN1 fascin actin-bundling protein 1 0.0329253
KLF6 Kruppel-like factor 6 0.0327551
RPL11 ribosomal protein L11 0.0322339
RPL37A ribosomal protein L37a 0.032131
SLMAP sarcolemma associated protein 0.0321175
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.0318684
PDGFB platelet-derived growth factor beta polypeptide 0.0318667
PTPRJ protein tyrosine phosphatase, receptor type, J 0.0317216
NIPBL Nipped-B homolog (Drosophila) 0.0316689
BCAR3 breast cancer anti-estrogen resistance 3 0.0311302
S100A11 S100 calcium binding protein A11 0.0308878
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 0.0307972
AHNAK AHNAK nucleoprotein 0.0304839
ZMIZ1 zinc finger, MIZ-type containing 1 0.0300085
ANGPTL4 angiopoietin-like 4 0.0298739
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0297283
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.0291768
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.0290053
PLAT plasminogen activator, tissue 0.0287585
PRELID2 PRELI domain containing 2 0.0284812
BIRC2 baculoviral IAP repeat containing 2 0.0284617
FRMD6 FERM domain containing 6 0.0283201
RPL19 ribosomal protein L19 0.0283026
KDM3A lysine (K)-specific demethylase 3A 0.0282905
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0282862
FMNL2 formin-like 2 0.0282146
SAMD9 sterile alpha motif domain containing 9 0.0281292
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.0278532
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.0273805
TPX2 TPX2, microtubule-associated 0.0273678

decreased expression

Symbol Name Standardized Value
LOC112694756 uncharaterized LOC112694756 -0.100233
NDRG1 N-myc downstream regulated 1 -0.0980877
HSPG2 heparan sulfate proteoglycan 2 -0.0640587
LAMA5 laminin, alpha 5 -0.0611805
POTEF POTE ankyrin domain family, member F -0.059927
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.0590057
EFHD2 EF-hand domain family, member D2 -0.0554801
IGF2 insulin-like growth factor 2 -0.0552405
DPYD dihydropyrimidine dehydrogenase -0.0505918
CYB5R3 cytochrome b5 reductase 3 -0.0468087
OSMR oncostatin M receptor -0.0428726
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0413429
RAB22A RAB22A, member RAS oncogene family -0.0409222
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like -0.0393436
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0383039
TAPBP TAP binding protein (tapasin) -0.0373367
HLA-B major histocompatibility complex, class I, B -0.036547
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0353271
TINAGL1 tubulointerstitial nephritis antigen-like 1 -0.0342767
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0342023
FLNA filamin A, alpha -0.0319586
EPHA2 EPH receptor A2 -0.0318238
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0317346
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0308734
PLEC plectin -0.0301225
SMAD3 SMAD family member 3 -0.0300941
ARF1 ADP-ribosylation factor 1 -0.0297875
MYADM myeloid-associated differentiation marker -0.0296027
IARS1 isoleucyl-tRNA synthetase 1 -0.0288791
HM13 histocompatibility (minor) 13 -0.0287541
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) -0.028474
EGR1 early growth response 1 -0.0282155
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -0.0279865
TTC3 tetratricopeptide repeat domain 3 -0.0277142
TXNRD1 thioredoxin reductase 1 -0.0275223
CLU clusterin -0.027499
AKAP9 A kinase (PRKA) anchor protein 9 -0.026742
SETX senataxin -0.0263888
CNTNAP3 contactin associated protein-like 3 -0.0262439
PDLIM5 PDZ and LIM domain 5 -0.0247536
FNBP4 formin binding protein 4 -0.0246015
INTS6 integrator complex subunit 6 -0.0240678
HMGA1 high mobility group AT-hook 1 -0.0238103
HIPK3 homeodomain interacting protein kinase 3 -0.0236567
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0233293
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 -0.0230207
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.0228654
SFPQ splicing factor proline/glutamine-rich -0.0224869
YBX1 Y box binding protein 1 -0.0224749
NTSR1 neurotensin receptor 1 (high affinity) -0.0224518
SLC30A7 solute carrier family 30 (zinc transporter), member 7 -0.0220773
MBNL1 muscleblind-like splicing regulator 1 -0.0215806
TPD52L2 tumor protein D52-like 2 -0.0213308
LDHA lactate dehydrogenase A -0.0211543
SOD2 superoxide dismutase 2, mitochondrial -0.0210695
PFN1 profilin 1 -0.0210652
KCTD9 potassium channel tetramerization domain containing 9 -0.0204494
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.0203688
MRPS6 mitochondrial ribosomal protein S6 -0.0202399
ITM2B integral membrane protein 2B -0.0202014
MON2 MON2 homolog (S. cerevisiae) -0.0201859
PKM pyruvate kinase, muscle -0.0200348
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0199278
CTSD cathepsin D -0.0199109
TRAM1 translocation associated membrane protein 1 -0.0197829
VEGFA vascular endothelial growth factor A -0.0196991
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -0.0196051
MECOM MDS1 and EVI1 complex locus -0.0194383
MYO9A myosin IXA -0.0193824
PJA2 praja ring finger 2, E3 ubiquitin protein ligase -0.0193184
PIBF1 progesterone immunomodulatory binding factor 1 -0.0190701
ZFAND3 zinc finger, AN1-type domain 3 -0.0189601
HMGA2 high mobility group AT-hook 2 -0.0189394
PCF11 PCF11 cleavage and polyadenylation factor subunit -0.018814
LYSMD3 LysM, putative peptidoglycan-binding, domain containing 3 -0.0184329
BLZF1 basic leucine zipper nuclear factor 1 -0.0180611
IQGAP1 IQ motif containing GTPase activating protein 1 -0.0180439
ARF4 ADP-ribosylation factor 4 -0.0180303
SYNPO synaptopodin -0.0178674
CARS1 cysteinyl-tRNA synthetase 1 -0.0177658
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A -0.0176122
DGKH diacylglycerol kinase, eta -0.017237
SRRM2 serine/arginine repetitive matrix 2 -0.0171368
HDAC8 histone deacetylase 8 -0.016961
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 -0.0169178
QSER1 glutamine and serine rich 1 -0.016901
COPB2 coatomer protein complex, subunit beta 2 (beta prime) -0.0168059
NECTIN1 nectin cell adhesion molecule 1 -0.0167528
TBC1D22A TBC1 domain family, member 22A -0.016689
TXNIP thioredoxin interacting protein -0.0166261
PPP1R15B protein phosphatase 1, regulatory subunit 15B -0.0164594
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 -0.016387
GOLGA2 golgin A2 -0.0163822
MBNL2 muscleblind-like splicing regulator 2 -0.0163412
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.0162917
PHKB phosphorylase kinase, beta -0.016287
THBD thrombomodulin -0.0162333
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.0161435
EXT1 exostosin glycosyltransferase 1 -0.0160481
ZNF207 zinc finger protein 207 -0.0160378