| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verapamil perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Verapamil_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0838792 |
| PTMA | prothymosin, alpha | 0.0662095 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.063344 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0534108 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0529375 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0432179 |
| EREG | epiregulin | 0.0402212 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0378421 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.035447 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0353394 |
| PUM2 | pumilio RNA-binding family member 2 | 0.034866 |
| NCKAP1 | NCK-associated protein 1 | 0.0337254 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0331381 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0326474 |
| ECT2 | epithelial cell transforming 2 | 0.0310996 |
| CCNL1 | cyclin L1 | 0.0307093 |
| ZNF292 | zinc finger protein 292 | 0.030377 |
| TPM3 | tropomyosin 3 | 0.030154 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0293669 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0291855 |
| RPS2 | ribosomal protein S2 | 0.029056 |
| ETNK1 | ethanolamine kinase 1 | 0.028621 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0274025 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0270995 |
| NUP58 | nucleoporin 58 | 0.0268806 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0266297 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0266292 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0260177 |
| RNF145 | ring finger protein 145 | 0.0259674 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0259401 |
| ARRDC3 | arrestin domain containing 3 | 0.0258834 |
| ENO1 | enolase 1, (alpha) | 0.0257499 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0255895 |
| SQSTM1 | sequestosome 1 | 0.0252686 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0251381 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0251061 |
| CENPF | centromere protein F, 350/400kDa | 0.0248731 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0244682 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0242698 |
| RPL3 | ribosomal protein L3 | 0.0237984 |
| H1-0 | H1.0 linker histone | 0.0234697 |
| HELZ | helicase with zinc finger | 0.0231834 |
| QKI | QKI, KH domain containing, RNA binding | 0.0231285 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0230867 |
| NEK7 | NIMA-related kinase 7 | 0.0224998 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0217922 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0217446 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0216384 |
| VCL | vinculin | 0.0215271 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0214583 |
| OGA | O-GlcNAcase | 0.0213246 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.021188 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0209182 |
| PCBP2 | poly(rC) binding protein 2 | 0.0208903 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0208353 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0208096 |
| WDR43 | WD repeat domain 43 | 0.0207339 |
| CDC73 | cell division cycle 73 | 0.0206155 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0204134 |
| ANLN | anillin, actin binding protein | 0.0204074 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0203354 |
| CAPRIN2 | caprin family member 2 | 0.0202896 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0202193 |
| FOSL1 | FOS-like antigen 1 | 0.0202138 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0201851 |
| SPAG9 | sperm associated antigen 9 | 0.0198957 |
| FNIP1 | folliculin interacting protein 1 | 0.0197869 |
| TOP1 | topoisomerase (DNA) I | 0.0197 |
| HBS1L | HBS1-like translational GTPase | 0.0192483 |
| TPX2 | TPX2, microtubule-associated | 0.0191599 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0190078 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0188577 |
| PER1 | period circadian clock 1 | 0.0185328 |
| HMGB2 | high mobility group box 2 | 0.0184877 |
| SETD5 | SET domain containing 5 | 0.0184122 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0181102 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0180768 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0179674 |
| MATR3 | matrin 3 | 0.0179041 |
| MKI67 | marker of proliferation Ki-67 | 0.0176954 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.017627 |
| HSPA8 | heat shock 70kDa protein 8 | 0.017447 |
| POU2F1 | POU class 2 homeobox 1 | 0.0173573 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0171679 |
| MAPK1 | mitogen-activated protein kinase 1 | 0.0170181 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0169994 |
| PDE8A | phosphodiesterase 8A | 0.0169446 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0166174 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0165215 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0164897 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0164881 |
| TFG | TRK-fused gene | 0.0164432 |
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase | 0.0164245 |
| RYK | receptor-like tyrosine kinase | 0.016417 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0163913 |
| RTTN | rotatin | 0.0163595 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0163449 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0162775 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0162465 |
| XPO1 | exportin 1 | 0.0161611 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.336378 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.188019 |
| MT2A | metallothionein 2A | -0.171783 |
| TP63 | tumor protein p63 | -0.144376 |
| TXNRD1 | thioredoxin reductase 1 | -0.123308 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.114928 |
| TMSB10 | thymosin beta 10 | -0.114093 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.112363 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.102183 |
| RPL35A | ribosomal protein L35a | -0.0992581 |
| CD44 | CD44 molecule (Indian blood group) | -0.0972024 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0933975 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0895104 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0884015 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0798758 |
| MT1X | metallothionein 1X | -0.0782609 |
| TMSB4X | thymosin beta 4, X-linked | -0.0765739 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0738191 |
| EGR1 | early growth response 1 | -0.0695614 |
| EHBP1 | EH domain binding protein 1 | -0.0690894 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0664655 |
| MT1E | metallothionein 1E | -0.0625787 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0615988 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0587542 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0585241 |
| HMGA1 | high mobility group AT-hook 1 | -0.0569565 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0552706 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0549085 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0539412 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0524197 |
| HLA-B | major histocompatibility complex, class I, B | -0.0519154 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0512651 |
| HDAC9 | histone deacetylase 9 | -0.0487272 |
| RUNX1 | runt-related transcription factor 1 | -0.0486387 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0484757 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0484304 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0474405 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0472413 |
| MYOF | myoferlin | -0.0465258 |
| FTL | ferritin, light polypeptide | -0.0442096 |
| BPTF | bromodomain PHD finger transcription factor | -0.0436704 |
| RPS6 | ribosomal protein S6 | -0.0412521 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0411426 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0399945 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0399161 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0393527 |
| RPL31 | ribosomal protein L31 | -0.0391819 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0390584 |
| RPL23 | ribosomal protein L23 | -0.0389853 |
| CMIP | c-Maf inducing protein | -0.0383647 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0382184 |
| LDHA | lactate dehydrogenase A | -0.0374023 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0373814 |
| EPHA4 | EPH receptor A4 | -0.0371159 |
| RAI1 | retinoic acid induced 1 | -0.0369534 |
| PDE10A | phosphodiesterase 10A | -0.0368665 |
| CANX | calnexin | -0.0368061 |
| DNER | delta/notch-like EGF repeat containing | -0.036754 |
| RPLP1 | ribosomal protein, large, P1 | -0.0360977 |
| RPL38 | ribosomal protein L38 | -0.034782 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0346719 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0346655 |
| CADM2 | cell adhesion molecule 2 | -0.0346521 |
| LOXL2 | lysyl oxidase-like 2 | -0.0346008 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0339998 |
| RPL28 | ribosomal protein L28 | -0.0334005 |
| RPLP0 | ribosomal protein, large, P0 | -0.0332227 |
| RPS24 | ribosomal protein S24 | -0.0326893 |
| VDAC1 | voltage-dependent anion channel 1 | -0.032661 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.0325012 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0324637 |
| RPL8 | ribosomal protein L8 | -0.0323817 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0323617 |
| TNS3 | tensin 3 | -0.0322682 |
| RPL36A | ribosomal protein L36a | -0.0321835 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0321003 |
| RPS13 | ribosomal protein S13 | -0.0316715 |
| RPS23 | ribosomal protein S23 | -0.0316261 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0315666 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0314291 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0314176 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.031226 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0312042 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0311384 |
| CALR | calreticulin | -0.0307283 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.030434 |
| USP34 | ubiquitin specific peptidase 34 | -0.029993 |
| OSMR | oncostatin M receptor | -0.0298051 |
| RPL7A | ribosomal protein L7a | -0.029782 |
| RPS19 | ribosomal protein S19 | -0.0296313 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0296029 |
| RIGI | RNA sensor RIG-I | -0.0295672 |
| PYGL | phosphorylase, glycogen, liver | -0.0295579 |
| TBCA | tubulin folding cofactor A | -0.0293454 |
| ACTG1 | actin gamma 1 | -0.0291294 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0286634 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0284454 |
| RPL26 | ribosomal protein L26 | -0.028386 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0283436 |
| RPS8 | ribosomal protein S8 | -0.0281054 |
