| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verapamil perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Verapamil_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAM13A | family with sequence similarity 13, member A | 0.132195 |
| MT2A | metallothionein 2A | 0.0936524 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0925095 |
| GRAMD1B | GRAM domain containing 1B | 0.0877534 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0669204 |
| TPD52 | tumor protein D52 | 0.0550267 |
| RNF145 | ring finger protein 145 | 0.0522831 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0497699 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0463771 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0431081 |
| GPC6 | glypican 6 | 0.0429415 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0414844 |
| HELZ | helicase with zinc finger | 0.0410166 |
| TSC22D2 | TSC22 domain family, member 2 | 0.040819 |
| NGLY1 | N-glycanase 1 | 0.0399666 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0398576 |
| PGK1 | phosphoglycerate kinase 1 | 0.0395482 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.039128 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0384108 |
| USP3 | ubiquitin specific peptidase 3 | 0.0377259 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0373107 |
| ATP13A3 | ATPase type 13A3 | 0.0371259 |
| NUP58 | nucleoporin 58 | 0.0362534 |
| NPTN | neuroplastin | 0.0355732 |
| H1-0 | H1.0 linker histone | 0.0349832 |
| TOP1 | topoisomerase (DNA) I | 0.0347489 |
| RUNX1 | runt-related transcription factor 1 | 0.0341562 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0329909 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0327864 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0325113 |
| NCKAP1 | NCK-associated protein 1 | 0.0321116 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0317083 |
| TFG | TRK-fused gene | 0.0315115 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0313008 |
| ZNF292 | zinc finger protein 292 | 0.0310784 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0304844 |
| ECT2 | epithelial cell transforming 2 | 0.0302271 |
| DTNA | dystrobrevin, alpha | 0.0295777 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0294926 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0294235 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0288774 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0281024 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0276263 |
| TMEM165 | transmembrane protein 165 | 0.0275887 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0270838 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0270483 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0266847 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0266835 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0257147 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0255318 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0249591 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0248192 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0239582 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0239165 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0238093 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0237797 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0234243 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0233571 |
| SETD5 | SET domain containing 5 | 0.0233401 |
| UVRAG | UV radiation resistance associated | 0.023063 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0228185 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0224606 |
| PDE8A | phosphodiesterase 8A | 0.0222517 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0220482 |
| CDC73 | cell division cycle 73 | 0.0218584 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.021667 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0211926 |
| SPPL3 | signal peptide peptidase like 3 | 0.0210625 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.021043 |
| ATG14 | autophagy related 14 | 0.02097 |
| ARRDC3 | arrestin domain containing 3 | 0.0205927 |
| QKI | QKI, KH domain containing, RNA binding | 0.0205021 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.020345 |
| TBK1 | TANK-binding kinase 1 | 0.0202736 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0202409 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0196183 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0192189 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0191966 |
| SLMAP | sarcolemma associated protein | 0.0189259 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0187901 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0185424 |
| SEPTIN10 | septin 10 | 0.0185258 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.018458 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0183017 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0182565 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0180495 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0179301 |
| WTAP | Wilms tumor 1 associated protein | 0.0178565 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0176613 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0174133 |
| ANXA5 | annexin A5 | 0.0173948 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.017332 |
| ENO1 | enolase 1, (alpha) | 0.0173226 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0171387 |
| MEF2A | myocyte enhancer factor 2A | 0.0170749 |
| RTN4 | reticulon 4 | 0.0170531 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0170235 |
| FOXJ3 | forkhead box J3 | 0.0169979 |
| VEGFC | vascular endothelial growth factor C | 0.0169713 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.016892 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | -0.416919 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.205568 |
| TXNRD1 | thioredoxin reductase 1 | -0.129991 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.112382 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.106019 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.086826 |
| EGR1 | early growth response 1 | -0.0795594 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0789812 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0720768 |
| NDRG1 | N-myc downstream regulated 1 | -0.0684284 |
| MCL1 | myeloid cell leukemia 1 | -0.0671573 |
| PKM | pyruvate kinase, muscle | -0.0665411 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0642131 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0628038 |
| LDHA | lactate dehydrogenase A | -0.0621001 |
| TMSB10 | thymosin beta 10 | -0.0606794 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0563082 |
| LAMC2 | laminin, gamma 2 | -0.0545522 |
| INTS6 | integrator complex subunit 6 | -0.0527 |
| ACTG1 | actin gamma 1 | -0.0524697 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0522934 |
| ASPH | aspartate beta-hydroxylase | -0.0522181 |
| GOLGB1 | golgin B1 | -0.0478206 |
| HDLBP | high density lipoprotein binding protein | -0.046154 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0453215 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0448917 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0442883 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0417845 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0416941 |
| MYO1E | myosin IE | -0.0403428 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0399785 |
| PLEC | plectin | -0.0397243 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0395197 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0395082 |
| ZNF638 | zinc finger protein 638 | -0.0382554 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0376617 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0372418 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0369229 |
| AHNAK | AHNAK nucleoprotein | -0.0363437 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0362835 |
| UBC | ubiquitin C | -0.036154 |
| S100A10 | S100 calcium binding protein A10 | -0.0358074 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.035457 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0350747 |
| RNF213 | ring finger protein 213 | -0.0348417 |
| CST3 | cystatin C | -0.0347956 |
| KRT8 | keratin 8, type II | -0.0345893 |
| HLA-B | major histocompatibility complex, class I, B | -0.0340833 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0340206 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0337463 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0329635 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0328793 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0328262 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0326337 |
| KRT18 | keratin 18, type I | -0.0325804 |
| LMO7 | LIM domain 7 | -0.0323115 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0320893 |
| CCND1 | cyclin D1 | -0.0320341 |
| SDC4 | syndecan 4 | -0.0317304 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0311211 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0310893 |
| SLTM | SAFB-like, transcription modulator | -0.0309838 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0309567 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0309429 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0305337 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0304114 |
| KRT7 | keratin 7, type II | -0.029819 |
| RPL35A | ribosomal protein L35a | -0.0295625 |
| CTBP2 | C-terminal binding protein 2 | -0.0288189 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0286822 |
| OSMR | oncostatin M receptor | -0.0285328 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0284168 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0283873 |
| SCEL | sciellin | -0.0278266 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0271524 |
| HMGA1 | high mobility group AT-hook 1 | -0.0269674 |
| CAV2 | caveolin 2 | -0.0261608 |
| CANX | calnexin | -0.0260236 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0259355 |
| EFNA5 | ephrin-A5 | -0.0258962 |
| FRY | furry homolog (Drosophila) | -0.0258657 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0256574 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0254533 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0252006 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | -0.0250945 |
| KIAA1217 | KIAA1217 | -0.0250002 |
| COPA | coatomer protein complex, subunit alpha | -0.0248163 |
| AGR2 | anterior gradient 2 | -0.0246438 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0246348 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | -0.0243721 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.024364 |
| ANXA1 | annexin A1 | -0.024145 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0240588 |
| EHBP1 | EH domain binding protein 1 | -0.0237508 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0233649 |
| TNS3 | tensin 3 | -0.0232659 |
| ABLIM1 | actin binding LIM protein 1 | -0.0232303 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.0231225 |
| B2M | beta-2-microglobulin | -0.0231202 |
| PERP | PERP, TP53 apoptosis effector | -0.0230203 |
