| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verapamil perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Verapamil_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.237819 |
| EGFR | epidermal growth factor receptor | 0.220699 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.115607 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.111951 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0939108 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0909522 |
| VIM | vimentin | 0.0875379 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0850344 |
| CD44 | CD44 molecule (Indian blood group) | 0.0847443 |
| EFNA5 | ephrin-A5 | 0.0841974 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.075021 |
| MT2A | metallothionein 2A | 0.0747441 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0697329 |
| MKI67 | marker of proliferation Ki-67 | 0.0692714 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0671867 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0665444 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.066219 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0647539 |
| OXR1 | oxidation resistance 1 | 0.0614897 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0608376 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0602582 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0593521 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0553873 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0547302 |
| NBAS | neuroblastoma amplified sequence | 0.0541614 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0541321 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0540124 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.0537532 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.052398 |
| CDH13 | cadherin 13 | 0.0523872 |
| PRKCA | protein kinase C, alpha | 0.0519561 |
| GOLGB1 | golgin B1 | 0.0512385 |
| CEP350 | centrosomal protein 350kDa | 0.0508923 |
| PCBP2 | poly(rC) binding protein 2 | 0.0503799 |
| COL5A2 | collagen, type V, alpha 2 | 0.0496971 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0488809 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0484 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0482855 |
| RORA | RAR-related orphan receptor A | 0.0479185 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0467006 |
| CCNI | cyclin I | 0.0466079 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0464707 |
| SBF2 | SET binding factor 2 | 0.0461048 |
| GPC6 | glypican 6 | 0.0460687 |
| SNX25 | sorting nexin 25 | 0.0457956 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0457594 |
| SMYD3 | SET and MYND domain containing 3 | 0.045322 |
| RUNX1 | runt-related transcription factor 1 | 0.0447554 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0439777 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.04373 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0433617 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0432944 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0431459 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0430372 |
| EXOC4 | exocyst complex component 4 | 0.042834 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0422294 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0418169 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0417837 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0407806 |
| APP | amyloid beta (A4) precursor protein | 0.0405647 |
| ABI1 | abl-interactor 1 | 0.0399618 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.038239 |
| PRELID2 | PRELI domain containing 2 | 0.0368094 |
| ENO1 | enolase 1, (alpha) | 0.0366364 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0364281 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0357157 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0354904 |
| PCBP3 | poly(rC) binding protein 3 | 0.0349536 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.034742 |
| SLTM | SAFB-like, transcription modulator | 0.0347332 |
| RTN4 | reticulon 4 | 0.0340262 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.034008 |
| DSTN | destrin (actin depolymerizing factor) | 0.0338687 |
| NF1 | neurofibromin 1 | 0.0336139 |
| FAM13A | family with sequence similarity 13, member A | 0.0335899 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0335474 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0331798 |
| CLASP1 | cytoplasmic linker associated protein 1 | 0.0331396 |
| MYO1E | myosin IE | 0.0322923 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0319379 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0318101 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0317529 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.030344 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0300028 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0299202 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0295694 |
| AK1 | adenylate kinase 1 | 0.0293214 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.029225 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0290886 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0290226 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0288663 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0288369 |
| ATP13A3 | ATPase type 13A3 | 0.028123 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.027746 |
| ASPH | aspartate beta-hydroxylase | 0.0274944 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0266663 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0264221 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0264035 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0260315 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0257878 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | -0.11147 |
| DSCAM | Down syndrome cell adhesion molecule | -0.108607 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0986458 |
| KRT17 | keratin 17, type I | -0.08926 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0843598 |
| TJP1 | tight junction protein 1 | -0.071446 |
| MUC16 | mucin 16, cell surface associated | -0.0713024 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0693519 |
| NAV2 | neuron navigator 2 | -0.0687345 |
| JMJD1C | jumonji domain containing 1C | -0.0674662 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0652238 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0651408 |
| RPS6 | ribosomal protein S6 | -0.0625698 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0620734 |
| OGA | O-GlcNAcase | -0.0616165 |
| FTL | ferritin, light polypeptide | -0.0590074 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | -0.0584061 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.057866 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | -0.0573244 |
| SETD2 | SET domain containing 2 | -0.056456 |
| SP100 | SP100 nuclear antigen | -0.0554144 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0535013 |
| SSH2 | slingshot protein phosphatase 2 | -0.0531584 |
| SRPK2 | SRSF protein kinase 2 | -0.053075 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0529781 |
| RPS24 | ribosomal protein S24 | -0.0528312 |
| RPLP0 | ribosomal protein, large, P0 | -0.0527232 |
| RPL37A | ribosomal protein L37a | -0.05236 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0521993 |
| XPO1 | exportin 1 | -0.0515975 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0509637 |
| B2M | beta-2-microglobulin | -0.0505942 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0472814 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0468912 |
| RPL12 | ribosomal protein L12 | -0.0468415 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0467621 |
| UBC | ubiquitin C | -0.0463295 |
| NPTN | neuroplastin | -0.0454748 |
| S100A9 | S100 calcium binding protein A9 | -0.045203 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0450386 |
| TMSB4X | thymosin beta 4, X-linked | -0.045004 |
| RPS20 | ribosomal protein S20 | -0.0445615 |
| POTEF | POTE ankyrin domain family, member F | -0.0441854 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0440866 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0440361 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0434298 |
| RPS19 | ribosomal protein S19 | -0.043316 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0431597 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0430202 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0425891 |
| SEPTIN9 | septin 9 | -0.0425804 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0424036 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0423789 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0423269 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.041992 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0412064 |
| ERBIN | erbb2 interacting protein | -0.0411731 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.041108 |
| CFDP1 | craniofacial development protein 1 | -0.040867 |
| PERP | PERP, TP53 apoptosis effector | -0.0403772 |
| FNIP1 | folliculin interacting protein 1 | -0.0400844 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0394006 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0388503 |
| THOC2 | THO complex 2 | -0.0388053 |
| S100A6 | S100 calcium binding protein A6 | -0.0387132 |
| VMP1 | vacuole membrane protein 1 | -0.0386048 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0375689 |
| GNAS | GNAS complex locus | -0.0374115 |
| RPS12 | ribosomal protein S12 | -0.0373425 |
| H3-3B | H3.3 histone B | -0.036736 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0367357 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0363881 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0363105 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.0359554 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0350379 |
| MEF2A | myocyte enhancer factor 2A | -0.0350022 |
| MXD1 | MAX dimerization protein 1 | -0.0348547 |
| RPL37 | ribosomal protein L37 | -0.0345795 |
| RBM39 | RNA binding motif protein 39 | -0.0340716 |
| RAB10 | RAB10, member RAS oncogene family | -0.0338745 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0337323 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0336821 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0335847 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0334998 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0331538 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0328411 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.03277 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0327581 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.032704 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0326182 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0324685 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0324002 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0322698 |
| NKTR | natural killer cell triggering receptor | -0.0322358 |
| TXNRD1 | thioredoxin reductase 1 | -0.0318383 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0317684 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0316001 |
| ABHD17C | abhydrolase domain containing 17C | -0.0312256 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0310439 |
| RPS25 | ribosomal protein S25 | -0.0307951 |
