| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verapamil perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Verapamil_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.143174 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0695184 |
| PRELID2 | PRELI domain containing 2 | 0.0638209 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0534671 |
| RPS12 | ribosomal protein S12 | 0.0471301 |
| CCNL1 | cyclin L1 | 0.0463963 |
| TMEM263 | transmembrane protein 263 | 0.0423673 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0423084 |
| TPM3 | tropomyosin 3 | 0.0416998 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.041266 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0404158 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0398837 |
| OGA | O-GlcNAcase | 0.0391412 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0388804 |
| TMEM165 | transmembrane protein 165 | 0.0388718 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0385919 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0381887 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0366101 |
| RPS3 | ribosomal protein S3 | 0.0352513 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0343047 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0342665 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0335568 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0326499 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0315878 |
| CRY1 | cryptochrome circadian clock 1 | 0.0308253 |
| NBAS | neuroblastoma amplified sequence | 0.0276313 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0274563 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0257038 |
| RPL37A | ribosomal protein L37a | 0.0256777 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0254755 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0250072 |
| ZNF292 | zinc finger protein 292 | 0.0249438 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.024831 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0246522 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0240712 |
| MYO6 | myosin VI | 0.0235417 |
| SNX14 | sorting nexin 14 | 0.0232676 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0231093 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.022826 |
| RPL6 | ribosomal protein L6 | 0.0227751 |
| PLAC8 | placenta-specific 8 | 0.0226919 |
| WBP11 | WW domain binding protein 11 | 0.0226765 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0224235 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.022403 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0223717 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0223494 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0222968 |
| H1-0 | H1.0 linker histone | 0.0222072 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0220775 |
| FOSL1 | FOS-like antigen 1 | 0.0220648 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0218291 |
| RPS2 | ribosomal protein S2 | 0.0218052 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0216206 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0214716 |
| H1-4 | H1.4 linker histone, cluster member | 0.0214138 |
| NEK7 | NIMA-related kinase 7 | 0.0211489 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0210938 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0209787 |
| SRPK1 | SRSF protein kinase 1 | 0.0209664 |
| ASPH | aspartate beta-hydroxylase | 0.0207692 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0207586 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.0207392 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0206836 |
| RAD51B | RAD51 paralog B | 0.0204482 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0203422 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0201656 |
| TMEM39A | transmembrane protein 39A | 0.0201039 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0201015 |
| YAP1 | Yes-associated protein 1 | 0.0200475 |
| GMCL1 | germ cell-less, spermatogenesis associated 1 | 0.0196357 |
| CIP2A | cellular inhibitor of PP2A | 0.0195372 |
| NEMF | nuclear export mediator factor | 0.0194889 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0193738 |
| EFTUD2 | elongation factor Tu GTP binding domain containing 2 | 0.0192243 |
| TFG | TRK-fused gene | 0.0189578 |
| SUCO | SUN domain containing ossification factor | 0.0188647 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0188174 |
| TNPO3 | transportin 3 | 0.0188146 |
| FNIP1 | folliculin interacting protein 1 | 0.0187961 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0187646 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0187545 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0187378 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0187032 |
| RPS7 | ribosomal protein S7 | 0.0186997 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | 0.018652 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa | 0.0186344 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.018594 |
| TPM4 | tropomyosin 4 | 0.0183814 |
| PDS5B | PDS5 cohesin associated factor B | 0.0183484 |
| SEC24A | SEC24 family member A | 0.0182369 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0182234 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0181826 |
| CD2AP | CD2-associated protein | 0.018178 |
| NEMP1 | nuclear envelope integral membrane protein 1 | 0.0181568 |
| XPO6 | exportin 6 | 0.018048 |
| FANCI | Fanconi anemia, complementation group I | 0.0179203 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0179152 |
| RAI1 | retinoic acid induced 1 | 0.0178606 |
| NUP58 | nucleoporin 58 | 0.0178029 |
| AK4 | adenylate kinase 4 | 0.017678 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.136343 |
| TXNRD1 | thioredoxin reductase 1 | -0.115508 |
| EGR1 | early growth response 1 | -0.106362 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.100384 |
| GRAMD1B | GRAM domain containing 1B | -0.0957551 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0834027 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0721112 |
| BPTF | bromodomain PHD finger transcription factor | -0.0677472 |
| VIM | vimentin | -0.0627413 |
| EGFR | epidermal growth factor receptor | -0.0603191 |
| SMAD3 | SMAD family member 3 | -0.0579899 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0554711 |
| CCND2 | cyclin D2 | -0.0543341 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0533097 |
| GPHN | gephyrin | -0.0497105 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0495498 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0492745 |
| CANX | calnexin | -0.0485997 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0464511 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0457579 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0457045 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0450089 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0447425 |
| YBX1 | Y box binding protein 1 | -0.0445489 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0443348 |
| FBXO11 | F-box protein 11 | -0.0440506 |
| NF1 | neurofibromin 1 | -0.0427502 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0426349 |
| RPL38 | ribosomal protein L38 | -0.0422886 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0419616 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0411311 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.041057 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0396611 |
| THOC2 | THO complex 2 | -0.0388215 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0385348 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0367801 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0363643 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.036027 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0349598 |
| MTA3 | metastasis associated 1 family, member 3 | -0.0348844 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0344683 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | -0.0343862 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0336957 |
| HMGA1 | high mobility group AT-hook 1 | -0.0336221 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0334667 |
| OSMR | oncostatin M receptor | -0.0334161 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0332138 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0324659 |
| THADA | thyroid adenoma associated | -0.0322144 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0317635 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0317563 |
| RPL5 | ribosomal protein L5 | -0.0315991 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0312141 |
| SMYD3 | SET and MYND domain containing 3 | -0.0307503 |
| HMGA2 | high mobility group AT-hook 2 | -0.0305529 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0302918 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.030143 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.030042 |
| RNF169 | ring finger protein 169 | -0.0298822 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.029823 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0294281 |
| AHNAK | AHNAK nucleoprotein | -0.0292803 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0292422 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0290107 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0287 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0286498 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0285213 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0284452 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0284421 |
| RPS4X | ribosomal protein S4, X-linked | -0.0284318 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0283629 |
| RANBP17 | RAN binding protein 17 | -0.0283148 |
| RPLP1 | ribosomal protein, large, P1 | -0.0282828 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0282812 |
| ACTN1 | actinin, alpha 1 | -0.0282016 |
| DENND5B | DENN/MADD domain containing 5B | -0.0282011 |
| CBX3 | chromobox homolog 3 | -0.0281951 |
| RPL27A | ribosomal protein L27a | -0.0278796 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0278605 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0276282 |
| ATF6 | activating transcription factor 6 | -0.0276208 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0274146 |
| ZNF638 | zinc finger protein 638 | -0.0272941 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0271647 |
| PTK2 | protein tyrosine kinase 2 | -0.0271052 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.026985 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0268589 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0267327 |
| RPL8 | ribosomal protein L8 | -0.0267212 |
| PPP4R3B | protein phosphatase 4 regulatory subunit 3B | -0.026669 |
| TWF1 | twinfilin actin binding protein 1 | -0.0265433 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0264869 |
| SBF2 | SET binding factor 2 | -0.0264855 |
| PKP4 | plakophilin 4 | -0.0262987 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0262935 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0262812 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0261125 |
| CCND1 | cyclin D1 | -0.0260797 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0259661 |
| STC1 | stanniocalcin 1 | -0.0258651 |
