| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verapamil perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Verapamil_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | 0.172706 |
| PTMA | prothymosin, alpha | 0.119039 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.108855 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.108399 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.101327 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0987942 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.081825 |
| PGK1 | phosphoglycerate kinase 1 | 0.0793211 |
| ENO1 | enolase 1, (alpha) | 0.077907 |
| MT2A | metallothionein 2A | 0.0775903 |
| LAMB3 | laminin, beta 3 | 0.0772787 |
| RPS3 | ribosomal protein S3 | 0.0771271 |
| ASPH | aspartate beta-hydroxylase | 0.0736915 |
| FAM13A | family with sequence similarity 13, member A | 0.0724434 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0695295 |
| ANXA2 | annexin A2 | 0.0624349 |
| RACK1 | receptor for activated C kinase 1 | 0.0606548 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0599971 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0575728 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0573103 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.055177 |
| G0S2 | G0/G1 switch 2 | 0.0539623 |
| ACTG1 | actin gamma 1 | 0.0539285 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0510864 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0492795 |
| RPL12 | ribosomal protein L12 | 0.0482638 |
| SQSTM1 | sequestosome 1 | 0.0473592 |
| RPL4 | ribosomal protein L4 | 0.0465884 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0441557 |
| LAMC2 | laminin, gamma 2 | 0.0441124 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0396963 |
| NCKAP1 | NCK-associated protein 1 | 0.0396154 |
| PLAUR | plasminogen activator, urokinase receptor | 0.039241 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0389737 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0387618 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0378389 |
| RPS12 | ribosomal protein S12 | 0.0369616 |
| RPL32 | ribosomal protein L32 | 0.0366735 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0366241 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0365119 |
| RPS19 | ribosomal protein S19 | 0.0364888 |
| H1-4 | H1.4 linker histone, cluster member | 0.0357409 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0352198 |
| RPS2 | ribosomal protein S2 | 0.0348038 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0345474 |
| TMEM263 | transmembrane protein 263 | 0.0343945 |
| RPL37A | ribosomal protein L37a | 0.0342125 |
| RPS29 | ribosomal protein S29 | 0.0336585 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0335395 |
| RPS8 | ribosomal protein S8 | 0.0324184 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0323325 |
| RPL6 | ribosomal protein L6 | 0.0323153 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0322436 |
| B2M | beta-2-microglobulin | 0.0322379 |
| H1-0 | H1.0 linker histone | 0.0319135 |
| FHIT | fragile histidine triad | 0.031876 |
| KLF6 | Kruppel-like factor 6 | 0.031744 |
| S100A10 | S100 calcium binding protein A10 | 0.0312985 |
| PAPOLA | poly(A) polymerase alpha | 0.0311783 |
| TMSB10 | thymosin beta 10 | 0.0307911 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0306314 |
| HMGB2 | high mobility group box 2 | 0.0305593 |
| HLA-A | major histocompatibility complex, class I, A | 0.0304736 |
| AREG | amphiregulin | 0.0302416 |
| GPX4 | glutathione peroxidase 4 | 0.0287405 |
| ZNF292 | zinc finger protein 292 | 0.0283263 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0281819 |
| FAM162A | family with sequence similarity 162, member A | 0.0281719 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0279768 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0279097 |
| RPS6 | ribosomal protein S6 | 0.0275677 |
| S100A11 | S100 calcium binding protein A11 | 0.0275377 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0269538 |
| ARRDC3 | arrestin domain containing 3 | 0.0266038 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0265518 |
| USP3 | ubiquitin specific peptidase 3 | 0.0265047 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0262431 |
| RNF145 | ring finger protein 145 | 0.0259109 |
| RPL19 | ribosomal protein L19 | 0.0254322 |
| WBP11 | WW domain binding protein 11 | 0.025124 |
| DSPP | dentin sialophosphoprotein | 0.0250821 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0246765 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0244979 |
| FOSL1 | FOS-like antigen 1 | 0.0243677 |
| RPS23 | ribosomal protein S23 | 0.0242509 |
| RPLP0 | ribosomal protein, large, P0 | 0.0241946 |
| RPL18 | ribosomal protein L18 | 0.0239319 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.023858 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0238112 |
| TKT | transketolase | 0.0233795 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0233336 |
| RPL27 | ribosomal protein L27 | 0.0230982 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0230286 |
| MKI67 | marker of proliferation Ki-67 | 0.0230224 |
| RPS17 | ribosomal protein S17 | 0.0230169 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0228853 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0228569 |
| RHEB | Ras homolog enriched in brain | 0.0226551 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0226102 |
| CORO1C | coronin, actin binding protein, 1C | 0.0225817 |
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | -0.169867 |
| ERBIN | erbb2 interacting protein | -0.0820364 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0789681 |
| VEGFA | vascular endothelial growth factor A | -0.0746016 |
| FN1 | fibronectin 1 | -0.0684408 |
| FBXO32 | F-box protein 32 | -0.059261 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0557541 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0551633 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0534507 |
| NDRG1 | N-myc downstream regulated 1 | -0.0507256 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0491176 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0487878 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0484012 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0454434 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0445519 |
| RPL35A | ribosomal protein L35a | -0.0442356 |
| DTNA | dystrobrevin, alpha | -0.0437307 |
| HMGA1 | high mobility group AT-hook 1 | -0.0436186 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0424051 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0420068 |
| JUP | junction plakoglobin | -0.0418648 |
| FAM3C | family with sequence similarity 3, member C | -0.0397541 |
| ZNF207 | zinc finger protein 207 | -0.0387277 |
| MYO1E | myosin IE | -0.0385962 |
| CCND1 | cyclin D1 | -0.0377243 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0373511 |
| FNBP4 | formin binding protein 4 | -0.0357892 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0353795 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.035107 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0347915 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.034577 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0345322 |
| COPA | coatomer protein complex, subunit alpha | -0.0344855 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0343831 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0337892 |
| RBM25 | RNA binding motif protein 25 | -0.0327317 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0325154 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0322614 |
| CDCP1 | CUB domain containing protein 1 | -0.0321829 |
| FBXO34 | F-box protein 34 | -0.03188 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0311318 |
| OCLN | occludin | -0.0308432 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0304396 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0298513 |
| NF1 | neurofibromin 1 | -0.0295381 |
| PKM | pyruvate kinase, muscle | -0.0289856 |
| CERT1 | ceramide transporter 1 | -0.0289828 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0285909 |
| JMJD1C | jumonji domain containing 1C | -0.0284847 |
| TJP1 | tight junction protein 1 | -0.0282979 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0278967 |
| PLSCR1 | phospholipid scramblase 1 | -0.0277208 |
| CTSD | cathepsin D | -0.0275705 |
| TMEM165 | transmembrane protein 165 | -0.0275306 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0274224 |
| EFNA5 | ephrin-A5 | -0.0268605 |
| OSMR | oncostatin M receptor | -0.0268312 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0268141 |
| ARF4 | ADP-ribosylation factor 4 | -0.0266993 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0264839 |
| PLEC | plectin | -0.0264211 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0262677 |
| ARF1 | ADP-ribosylation factor 1 | -0.026192 |
| TPM4 | tropomyosin 4 | -0.0259798 |
| PTK2 | protein tyrosine kinase 2 | -0.0258406 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0256995 |
| TAPBP | TAP binding protein (tapasin) | -0.0256785 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0254638 |
| EGR1 | early growth response 1 | -0.0254217 |
| TXNRD1 | thioredoxin reductase 1 | -0.0253272 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0252942 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0251732 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0250886 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.025002 |
| GOLGB1 | golgin B1 | -0.0250019 |
| RBM47 | RNA binding motif protein 47 | -0.0249789 |
| FNIP1 | folliculin interacting protein 1 | -0.0249781 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0249723 |
| CANX | calnexin | -0.0249191 |
| FBXO11 | F-box protein 11 | -0.0244721 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0243903 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0243532 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0241971 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0240256 |
| PGBD5 | piggyBac transposable element derived 5 | -0.0239414 |
| SVIL | supervillin | -0.0238233 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0237351 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | -0.0236239 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0236203 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0235276 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0234713 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0233924 |
| MYO6 | myosin VI | -0.023238 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0231887 |
| ATXN1 | ataxin 1 | -0.023045 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0227657 |
| ZNF148 | zinc finger protein 148 | -0.0226615 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0224369 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0222323 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.022229 |
