| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verapamil perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Verapamil_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MKI67 | marker of proliferation Ki-67 | 0.0664743 |
| H1-4 | H1.4 linker histone, cluster member | 0.0628303 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0502888 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0492609 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0487109 |
| CENPF | centromere protein F, 350/400kDa | 0.0471434 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0450486 |
| SPAG9 | sperm associated antigen 9 | 0.0432343 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0413244 |
| COL3A1 | collagen, type III, alpha 1 | 0.0385417 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0365029 |
| SGO2 | shugoshin 2 | 0.0357553 |
| RIGI | RNA sensor RIG-I | 0.0354526 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0350276 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0346924 |
| RPL4 | ribosomal protein L4 | 0.0345275 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0330091 |
| CKAP2 | cytoskeleton associated protein 2 | 0.031812 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0314887 |
| H1-0 | H1.0 linker histone | 0.0298631 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.029741 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.029558 |
| RCOR1 | REST corepressor 1 | 0.0275442 |
| GPC3 | glypican 3 | 0.0273277 |
| RPS2 | ribosomal protein S2 | 0.0272419 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0272076 |
| MED12L | mediator complex subunit 12-like | 0.0258677 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0258282 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0257368 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0250286 |
| CUL4B | cullin 4B | 0.0249842 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.0249316 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0248275 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | 0.0242862 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0237657 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0228129 |
| CEP350 | centrosomal protein 350kDa | 0.0226331 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0221602 |
| ENO1 | enolase 1, (alpha) | 0.0220734 |
| PRELID2 | PRELI domain containing 2 | 0.0219568 |
| ANXA1 | annexin A1 | 0.0217788 |
| ZFP36 | ZFP36 ring finger protein | 0.0216261 |
| PSMD8 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 0.0215969 |
| ANXA5 | annexin A5 | 0.0212237 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0207529 |
| OPHN1 | oligophrenin 1 | 0.0204054 |
| MEF2A | myocyte enhancer factor 2A | 0.0203737 |
| TOX | thymocyte selection-associated high mobility group box | 0.0202717 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.020261 |
| TFRC | transferrin receptor | 0.0202514 |
| UGGT1 | UDP-glucose glycoprotein glucosyltransferase 1 | 0.0201534 |
| NBAS | neuroblastoma amplified sequence | 0.0199174 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0196605 |
| BPTF | bromodomain PHD finger transcription factor | 0.019616 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0195539 |
| FRYL | FRY-like | 0.0194903 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0194534 |
| SZRD1 | SUZ RNA binding domain containing 1 | 0.0193164 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0193123 |
| DST | dystonin | 0.0192659 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0192537 |
| EIF3I | eukaryotic translation initiation factor 3, subunit I | 0.0192439 |
| SRP9 | signal recognition particle 9kDa | 0.019016 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0190153 |
| KNL1 | kinetochore scaffold 1 | 0.018882 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0188636 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0186707 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0185882 |
| ILRUN | inflammation and lipid regulator with UBA-like and NBR1-like domains | 0.0185878 |
| LIN28B | lin-28 homolog B (C. elegans) | 0.0185305 |
| BCAP31 | B-cell receptor-associated protein 31 | 0.0184936 |
| IGF2BP1 | insulin-like growth factor 2 mRNA binding protein 1 | 0.0184187 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | 0.018401 |
| UPP1 | uridine phosphorylase 1 | 0.0183525 |
| H1-2 | H1.2 linker histone, cluster member | 0.0183362 |
| NUP98 | nucleoporin 98kDa | 0.0181842 |
| GPHN | gephyrin | 0.0181527 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | 0.0180017 |
| ECT2 | epithelial cell transforming 2 | 0.0178847 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0177855 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0177235 |
| HDAC9 | histone deacetylase 9 | 0.0177058 |
| TASOR2 | transcription activation suppressor family member 2 | 0.0176522 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0176414 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0175007 |
| NGLY1 | N-glycanase 1 | 0.017386 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0172737 |
| CDC14A | cell division cycle 14A | 0.0172057 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0172011 |
| TMEM135 | transmembrane protein 135 | 0.0170793 |
| NUP107 | nucleoporin 107kDa | 0.0169798 |
| RPL3 | ribosomal protein L3 | 0.0169568 |
| ETV1 | ets variant 1 | 0.0169228 |
| SQSTM1 | sequestosome 1 | 0.0169103 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0168989 |
| KIAA1328 | KIAA1328 | 0.0168922 |
| NDUFS1 | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 0.016631 |
| NOTCH2 | notch 2 | 0.0165585 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0165442 |
| MYEF2 | myelin expression factor 2 | 0.0165425 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | -0.137889 |
| TSC22D2 | TSC22 domain family, member 2 | -0.132903 |
| ITGAV | integrin, alpha V | -0.124417 |
| VIM | vimentin | -0.120772 |
| PEG10 | paternally expressed 10 | -0.110047 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.103479 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0969031 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0937997 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0841098 |
| PHIP | pleckstrin homology domain interacting protein | -0.0836097 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.079837 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0752892 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0719462 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0693515 |
| PLPP1 | phospholipid phosphatase 1 | -0.0688285 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0676991 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0652811 |
| FBXO11 | F-box protein 11 | -0.0642467 |
| TMSB10 | thymosin beta 10 | -0.0618233 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0608503 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.058576 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0559959 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0554749 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0537277 |
| PFN1 | profilin 1 | -0.0535132 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0526597 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0525542 |
| PRR16 | proline rich 16 | -0.0510004 |
| TENM3 | teneurin transmembrane protein 3 | -0.0501545 |
| METAP2 | methionyl aminopeptidase 2 | -0.0471305 |
| CALR | calreticulin | -0.0464577 |
| RPS16 | ribosomal protein S16 | -0.0450835 |
| SRP54 | signal recognition particle 54kDa | -0.0446087 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0431847 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0431492 |
| LYST | lysosomal trafficking regulator | -0.0430061 |
| FBL | fibrillarin | -0.0429346 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0429238 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0423404 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0422607 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0422132 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0417858 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0414203 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0410361 |
| PTMA | prothymosin, alpha | -0.0404493 |
| TXNRD1 | thioredoxin reductase 1 | -0.0402208 |
| RAI1 | retinoic acid induced 1 | -0.0401678 |
| ZNF207 | zinc finger protein 207 | -0.0401645 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | -0.0399794 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0396844 |
| LDHA | lactate dehydrogenase A | -0.0395007 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.039234 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.03899 |
| RBM25 | RNA binding motif protein 25 | -0.0387199 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0378221 |
| POTEF | POTE ankyrin domain family, member F | -0.0378175 |
| EMP1 | epithelial membrane protein 1 | -0.0374319 |
| NOP58 | NOP58 ribonucleoprotein | -0.0374318 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.037363 |
| RAD51B | RAD51 paralog B | -0.0373258 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0356929 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0353322 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0350454 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0343158 |
| RBM39 | RNA binding motif protein 39 | -0.0342162 |
| MAP4 | microtubule-associated protein 4 | -0.0339707 |
| PGK1 | phosphoglycerate kinase 1 | -0.0338383 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0337922 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0336887 |
| RFPL4B | ret finger protein-like 4B | -0.0336139 |
| SETD5 | SET domain containing 5 | -0.0332639 |
| RLF | rearranged L-myc fusion | -0.0332362 |
| GOLGA4 | golgin A4 | -0.033166 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0326583 |
| DMD | dystrophin | -0.0320341 |
| MAP1B | microtubule-associated protein 1B | -0.0316121 |
| NRG1 | neuregulin 1 | -0.0314229 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0311552 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.030842 |
| COL1A2 | collagen, type I, alpha 2 | -0.0308154 |
| MEIS2 | Meis homeobox 2 | -0.030797 |
| USP15 | ubiquitin specific peptidase 15 | -0.0307953 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0307056 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0306896 |
| TMEM123 | transmembrane protein 123 | -0.030672 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0306551 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0304517 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0304398 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0297705 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0296341 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0295931 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0294373 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0292933 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0292474 |
| THBS1 | thrombospondin 1 | -0.0291599 |
| PCBP2 | poly(rC) binding protein 2 | -0.0291231 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0291218 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.029026 |
| CDC73 | cell division cycle 73 | -0.0290193 |
| MYO10 | myosin X | -0.0289664 |
