| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verapamil perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Verapamil_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.279629 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.107671 |
| ZNF292 | zinc finger protein 292 | 0.0938783 |
| RPS6 | ribosomal protein S6 | 0.0713136 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.065869 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0645153 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0637279 |
| RPS19 | ribosomal protein S19 | 0.0586485 |
| RPS3 | ribosomal protein S3 | 0.0584608 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0574348 |
| TFG | TRK-fused gene | 0.053263 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0517307 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0488683 |
| RPS8 | ribosomal protein S8 | 0.0481343 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0480975 |
| ECT2 | epithelial cell transforming 2 | 0.0460369 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0458858 |
| RPS12 | ribosomal protein S12 | 0.0456748 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.043375 |
| CCNL1 | cyclin L1 | 0.0417558 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0415356 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0414726 |
| RPL37A | ribosomal protein L37a | 0.0411294 |
| RPL19 | ribosomal protein L19 | 0.0410734 |
| SETD5 | SET domain containing 5 | 0.0405162 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.037727 |
| CDC73 | cell division cycle 73 | 0.0369268 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0368913 |
| QKI | QKI, KH domain containing, RNA binding | 0.0368309 |
| RPS29 | ribosomal protein S29 | 0.0367819 |
| MT2A | metallothionein 2A | 0.036328 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0361199 |
| PDS5B | PDS5 cohesin associated factor B | 0.0359638 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.035727 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0356997 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0352987 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0352931 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.035138 |
| RPL3 | ribosomal protein L3 | 0.0350499 |
| PCBP2 | poly(rC) binding protein 2 | 0.0347939 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0344303 |
| FAM168A | family with sequence similarity 168, member A | 0.0342197 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0336999 |
| RPL9 | ribosomal protein L9 | 0.0335763 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0334537 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0331219 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0330172 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0329117 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0327544 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0319044 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0305747 |
| PHIP | pleckstrin homology domain interacting protein | 0.0303119 |
| RPS14 | ribosomal protein S14 | 0.0302561 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0302501 |
| NUP58 | nucleoporin 58 | 0.0301896 |
| RPL36 | ribosomal protein L36 | 0.0298676 |
| HELZ | helicase with zinc finger | 0.0292607 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0288071 |
| PRRC2C | proline-rich coiled-coil 2C | 0.028757 |
| COPA | coatomer protein complex, subunit alpha | 0.028703 |
| PER1 | period circadian clock 1 | 0.0282834 |
| MKI67 | marker of proliferation Ki-67 | 0.0276759 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.027432 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0273168 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0272949 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0272092 |
| ZNF451 | zinc finger protein 451 | 0.0270851 |
| PDGFC | platelet derived growth factor C | 0.0268853 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0267329 |
| SRP54 | signal recognition particle 54kDa | 0.0264429 |
| RPLP2 | ribosomal protein, large, P2 | 0.0263893 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0261578 |
| FNDC3B | fibronectin type III domain containing 3B | 0.026101 |
| RPL34 | ribosomal protein L34 | 0.0259295 |
| CRY1 | cryptochrome circadian clock 1 | 0.0258476 |
| ATF4 | activating transcription factor 4 | 0.0257209 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0256042 |
| USP3 | ubiquitin specific peptidase 3 | 0.0255318 |
| DSTN | destrin (actin depolymerizing factor) | 0.0253489 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.025121 |
| HDGF | hepatoma-derived growth factor | 0.0250598 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0249219 |
| RPL21 | ribosomal protein L21 | 0.0246677 |
| RPS10 | ribosomal protein S10 | 0.0245076 |
| CASC3 | cancer susceptibility candidate 3 | 0.0243602 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0243202 |
| RPS2 | ribosomal protein S2 | 0.0242029 |
| TMF1 | TATA element modulatory factor 1 | 0.0241901 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0241111 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.024078 |
| NCKAP1 | NCK-associated protein 1 | 0.0239759 |
| RPLP1 | ribosomal protein, large, P1 | 0.0239673 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.023919 |
| FTL | ferritin, light polypeptide | 0.0237042 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0236944 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0234353 |
| RPL12 | ribosomal protein L12 | 0.0233163 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0232044 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0231967 |
| VMP1 | vacuole membrane protein 1 | 0.0231838 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | -0.153739 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.133383 |
| EGFR | epidermal growth factor receptor | -0.129763 |
| TMSB4X | thymosin beta 4, X-linked | -0.127879 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.123381 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.115859 |
| PKM | pyruvate kinase, muscle | -0.112808 |
| FLNB | filamin B, beta | -0.105477 |
| TXNRD1 | thioredoxin reductase 1 | -0.100937 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0967686 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0867114 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0848817 |
| NBEA | neurobeachin | -0.0838525 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0733185 |
| LDHA | lactate dehydrogenase A | -0.0687071 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0664974 |
| PYGB | phosphorylase, glycogen; brain | -0.0644219 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0628609 |
| CCND1 | cyclin D1 | -0.0621605 |
| GLI2 | GLI family zinc finger 2 | -0.0584799 |
| S100A6 | S100 calcium binding protein A6 | -0.0574801 |
| VCL | vinculin | -0.053729 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.052251 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0521818 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0511833 |
| EZR | ezrin | -0.0499923 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0471845 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0464885 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0457811 |
| OSMR | oncostatin M receptor | -0.0445824 |
| NF1 | neurofibromin 1 | -0.0444976 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0431262 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0428709 |
| GLI3 | GLI family zinc finger 3 | -0.0428684 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.0427293 |
| EFNA5 | ephrin-A5 | -0.042709 |
| SMYD3 | SET and MYND domain containing 3 | -0.0416157 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0390483 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0389838 |
| LOXL3 | lysyl oxidase-like 3 | -0.0384327 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0384227 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0379394 |
| SBF2 | SET binding factor 2 | -0.0371452 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0366883 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0365443 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0364924 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0363898 |
| SQSTM1 | sequestosome 1 | -0.0361321 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 | -0.0357214 |
| MYO5C | myosin VC | -0.0348888 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0342661 |
| BMP10 | bone morphogenetic protein 10 | -0.0330547 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0323399 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0320348 |
| TJP1 | tight junction protein 1 | -0.0318133 |
| ANK2 | ankyrin 2, neuronal | -0.0317391 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0306564 |
| DUSP4 | dual specificity phosphatase 4 | -0.0303356 |
| BMP2K | BMP2 inducible kinase | -0.0302136 |
| FOXP1 | forkhead box P1 | -0.0301888 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.029868 |
| ATP9B | ATPase, class II, type 9B | -0.0298615 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0296345 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0292969 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0292793 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0292437 |
| S100A4 | S100 calcium binding protein A4 | -0.0284001 |
| RHBDD1 | rhomboid domain containing 1 | -0.0282818 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0282112 |
| EXOC6B | exocyst complex component 6B | -0.0280387 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0280312 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0279482 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0279346 |
| SLC38A2 | solute carrier family 38, member 2 | -0.027743 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -0.0275701 |
| FAM117B | family with sequence similarity 117, member B | -0.0274689 |
| APP | amyloid beta (A4) precursor protein | -0.0271288 |
| METTL15 | methyltransferase like 15 | -0.0269571 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0266889 |
| BPTF | bromodomain PHD finger transcription factor | -0.0264957 |
| PRPF38B | pre-mRNA processing factor 38B | -0.0264636 |
| ENOSF1 | enolase superfamily member 1 | -0.026401 |
| CD47 | CD47 molecule | -0.0258589 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0255796 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0255275 |
| DGKH | diacylglycerol kinase, eta | -0.0253544 |
| HDLBP | high density lipoprotein binding protein | -0.0251438 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0250531 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0249344 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0247134 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0245095 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0243212 |
| FNBP4 | formin binding protein 4 | -0.0242285 |
| SDCBP | syndecan binding protein (syntenin) | -0.0240306 |
| PRELID2 | PRELI domain containing 2 | -0.0238464 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.023558 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0233336 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0231737 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0229901 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0229454 |
