| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verapamil perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Verapamil_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.102926 |
| VCL | vinculin | 0.0797616 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0786705 |
| FN1 | fibronectin 1 | 0.0751761 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0656 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0551903 |
| CCNL1 | cyclin L1 | 0.053066 |
| PTMA | prothymosin, alpha | 0.0431228 |
| MKI67 | marker of proliferation Ki-67 | 0.0408832 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0401384 |
| CENPF | centromere protein F, 350/400kDa | 0.0396307 |
| MSN | moesin | 0.0390555 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0376689 |
| KIF4A | kinesin family member 4A | 0.0375571 |
| FNIP1 | folliculin interacting protein 1 | 0.0374907 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0365021 |
| ARRDC3 | arrestin domain containing 3 | 0.0364931 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0362897 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0360352 |
| MYOF | myoferlin | 0.035742 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0351521 |
| NAV2 | neuron navigator 2 | 0.0343572 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0320592 |
| WTAP | Wilms tumor 1 associated protein | 0.0318399 |
| PCBP2 | poly(rC) binding protein 2 | 0.031619 |
| MT2A | metallothionein 2A | 0.0304981 |
| TPX2 | TPX2, microtubule-associated | 0.0300351 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0266969 |
| RTN4 | reticulon 4 | 0.0262249 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0260338 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0251518 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0250381 |
| JMJD1C | jumonji domain containing 1C | 0.0249453 |
| RPL37A | ribosomal protein L37a | 0.0246539 |
| HELZ | helicase with zinc finger | 0.0238185 |
| RPS12 | ribosomal protein S12 | 0.0236513 |
| CALD1 | caldesmon 1 | 0.0232589 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0229492 |
| CADM1 | cell adhesion molecule 1 | 0.0225342 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0222519 |
| TGFB2 | transforming growth factor, beta 2 | 0.0219702 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0211721 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0210995 |
| CENPE | centromere protein E, 312kDa | 0.0210801 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0210393 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0210152 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0208359 |
| CLIC4 | chloride intracellular channel 4 | 0.0206671 |
| RAD51B | RAD51 paralog B | 0.0201494 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0199081 |
| EPHA6 | EPH receptor A6 | 0.0197963 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.019707 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0196615 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0195958 |
| VMP1 | vacuole membrane protein 1 | 0.0195588 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0194735 |
| RPS2 | ribosomal protein S2 | 0.0194422 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0191449 |
| KIF11 | kinesin family member 11 | 0.0190939 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0189264 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.018663 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0185518 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0183214 |
| ARFGEF3 | ARFGEF family member 3 | 0.0182331 |
| KIF18A | kinesin family member 18A | 0.0181518 |
| DIAPH3 | diaphanous-related formin 3 | 0.017988 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0179426 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0179292 |
| LRRC7 | leucine rich repeat containing 7 | 0.0177644 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.017709 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.017706 |
| RPS23 | ribosomal protein S23 | 0.0176666 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0176393 |
| FLNB | filamin B, beta | 0.0176255 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0175874 |
| HDAC9 | histone deacetylase 9 | 0.0175739 |
| ADAR | adenosine deaminase, RNA-specific | 0.0173266 |
| PALLD | palladin, cytoskeletal associated protein | 0.0170295 |
| B2M | beta-2-microglobulin | 0.0169898 |
| FRMD5 | FERM domain containing 5 | 0.016578 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0164751 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0164191 |
| SETD5 | SET domain containing 5 | 0.0161419 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0161277 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0158372 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0157632 |
| FLOT1 | flotillin 1 | 0.0154851 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0154174 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0154074 |
| CYRIB | CYFIP related Rac1 interactor B | 0.015388 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0152763 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0152465 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0152063 |
| SCFD1 | sec1 family domain containing 1 | 0.0150627 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0150192 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0149896 |
| CTSA | cathepsin A | 0.0149547 |
| BRD2 | bromodomain containing 2 | 0.0149201 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0146913 |
| RPS3 | ribosomal protein S3 | 0.0146736 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.298414 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.198119 |
| GLIS3 | GLIS family zinc finger 3 | -0.176117 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.119315 |
| PGK1 | phosphoglycerate kinase 1 | -0.102203 |
| COL6A3 | collagen, type VI, alpha 3 | -0.100382 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0886402 |
| TMSB4X | thymosin beta 4, X-linked | -0.0870994 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0870636 |
| HMGA2 | high mobility group AT-hook 2 | -0.0813596 |
| CD44 | CD44 molecule (Indian blood group) | -0.0785518 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0781475 |
| AHNAK | AHNAK nucleoprotein | -0.0739433 |
| IER3 | immediate early response 3 | -0.0711843 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0710725 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.068196 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0629779 |
| CDH13 | cadherin 13 | -0.0628207 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0622708 |
| NDRG1 | N-myc downstream regulated 1 | -0.0598334 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0582658 |
| RAI14 | retinoic acid induced 14 | -0.057977 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0576971 |
| STC1 | stanniocalcin 1 | -0.057101 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0570683 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0557337 |
| CANX | calnexin | -0.0553547 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0552542 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0550887 |
| VEGFA | vascular endothelial growth factor A | -0.0545474 |
| HLA-E | major histocompatibility complex, class I, E | -0.0543749 |
| LDHA | lactate dehydrogenase A | -0.0538414 |
| HLA-B | major histocompatibility complex, class I, B | -0.0537569 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.053644 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0528449 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0523424 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0512936 |
| FRMD4A | FERM domain containing 4A | -0.0502183 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0500031 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0485648 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0475331 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0472167 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.046125 |
| LOX | lysyl oxidase | -0.044987 |
| NAV1 | neuron navigator 1 | -0.0442741 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0436281 |
| EGFR | epidermal growth factor receptor | -0.0431422 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0426762 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0419265 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0418539 |
| GNAS | GNAS complex locus | -0.0408221 |
| TPM4 | tropomyosin 4 | -0.0397267 |
| COL5A1 | collagen, type V, alpha 1 | -0.0394124 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.039229 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0391866 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.038197 |
| SMAD3 | SMAD family member 3 | -0.0373178 |
| EFNA5 | ephrin-A5 | -0.0371152 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0355482 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0350863 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0347796 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0342644 |
| CALR | calreticulin | -0.0341199 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0337646 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0331827 |
| MMP12 | matrix metallopeptidase 12 | -0.0325293 |
| RND3 | Rho family GTPase 3 | -0.0322594 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0313914 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0312765 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0312744 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0311932 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0311465 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0309702 |
| RPS6 | ribosomal protein S6 | -0.0308604 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0306238 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0302837 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.030151 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0298836 |
| DEK | DEK proto-oncogene | -0.0290237 |
| ATP13A3 | ATPase type 13A3 | -0.0290232 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0286865 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0286402 |
| INHBA | inhibin, beta A | -0.0280413 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0279864 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0276698 |
| ANXA2 | annexin A2 | -0.0276566 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0275697 |
| FAM20C | family with sequence similarity 20, member C | -0.027253 |
| CTSB | cathepsin B | -0.0270362 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.027016 |
| CLMP | CXADR-like membrane protein | -0.0269162 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0268895 |
| TPM1 | tropomyosin 1 (alpha) | -0.0268492 |
| FOXP1 | forkhead box P1 | -0.0267808 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0266309 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0264183 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0261835 |
| TMSB10 | thymosin beta 10 | -0.0261294 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0257682 |
| SEPTIN7 | septin 7 | -0.0257167 |
