| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verapamil perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Verapamil_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.252748 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.142036 |
| FTL | ferritin, light polypeptide | 0.131603 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.113794 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0970544 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0902815 |
| VIM | vimentin | 0.0889248 |
| ENO1 | enolase 1, (alpha) | 0.0858258 |
| HLA-B | major histocompatibility complex, class I, B | 0.0820675 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0744982 |
| ANXA2 | annexin A2 | 0.0653048 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0650938 |
| NDRG1 | N-myc downstream regulated 1 | 0.0639138 |
| MT1X | metallothionein 1X | 0.0620801 |
| SEC24A | SEC24 family member A | 0.0590606 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0569127 |
| B2M | beta-2-microglobulin | 0.0568712 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0565891 |
| STC1 | stanniocalcin 1 | 0.0558026 |
| CALU | calumenin | 0.0546908 |
| NRXN3 | neurexin 3 | 0.0514363 |
| EGFR | epidermal growth factor receptor | 0.0507658 |
| PGK1 | phosphoglycerate kinase 1 | 0.0495124 |
| GOLGA4 | golgin A4 | 0.049162 |
| HLA-A | major histocompatibility complex, class I, A | 0.0481103 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0472116 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0451486 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.045043 |
| RPL37A | ribosomal protein L37a | 0.0446235 |
| RNF145 | ring finger protein 145 | 0.043312 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0397042 |
| RPS3 | ribosomal protein S3 | 0.0393385 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0389354 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0383501 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0381199 |
| PTMA | prothymosin, alpha | 0.037846 |
| ANXA5 | annexin A5 | 0.0369216 |
| MSN | moesin | 0.0366321 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0365597 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0363093 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0362525 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0359405 |
| CENPF | centromere protein F, 350/400kDa | 0.0352967 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0352033 |
| RPL34 | ribosomal protein L34 | 0.0349341 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0346174 |
| MORF4L2 | mortality factor 4 like 2 | 0.0340669 |
| VEGFC | vascular endothelial growth factor C | 0.0340341 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0339103 |
| TMEM165 | transmembrane protein 165 | 0.0335641 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0333384 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.033032 |
| RND3 | Rho family GTPase 3 | 0.0329577 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0328752 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.032874 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0324863 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0324602 |
| RPS23 | ribosomal protein S23 | 0.0323905 |
| PTGES2 | prostaglandin E synthase 2 | 0.0322454 |
| SETD5 | SET domain containing 5 | 0.0321917 |
| ATP13A3 | ATPase type 13A3 | 0.0321791 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0320185 |
| THBS1 | thrombospondin 1 | 0.0318809 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0317841 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0317677 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0314062 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0310677 |
| SEPTIN2 | septin 2 | 0.0308138 |
| RACK1 | receptor for activated C kinase 1 | 0.0307444 |
| RNF216 | ring finger protein 216 | 0.0306732 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0303206 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0302907 |
| COG5 | component of oligomeric golgi complex 5 | 0.0302891 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0301107 |
| PRSS23 | protease, serine, 23 | 0.0300542 |
| GRID1 | glutamate receptor, ionotropic, delta 1 | 0.029706 |
| EFNA5 | ephrin-A5 | 0.029393 |
| ASPH | aspartate beta-hydroxylase | 0.029328 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0289325 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa | 0.0287467 |
| RPS2 | ribosomal protein S2 | 0.0284493 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0280058 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0276513 |
| RPL12 | ribosomal protein L12 | 0.0274624 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0271488 |
| YEATS2 | YEATS domain containing 2 | 0.0269025 |
| MYSM1 | Myb-like, SWIRM and MPN domains 1 | 0.0268191 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0264934 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0264762 |
| SFXN1 | sideroflexin 1 | 0.0263933 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0263488 |
| RPLP2 | ribosomal protein, large, P2 | 0.0262915 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0262297 |
| TPM2 | tropomyosin 2 (beta) | 0.0259996 |
| CA12 | carbonic anhydrase XII | 0.0259618 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0259582 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.0256463 |
| SRP54 | signal recognition particle 54kDa | 0.0256256 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0254738 |
| CLINT1 | clathrin interactor 1 | 0.0252038 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0778733 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0680372 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0633342 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0607516 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0591618 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0559821 |
| SDC4 | syndecan 4 | -0.0530358 |
| VEGFA | vascular endothelial growth factor A | -0.0519736 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0515671 |
| ERBIN | erbb2 interacting protein | -0.0511201 |
| IL6 | interleukin 6 | -0.0502781 |
| COL1A1 | collagen, type I, alpha 1 | -0.0453803 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0445651 |
| COL1A2 | collagen, type I, alpha 2 | -0.0409448 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0403378 |
| USP34 | ubiquitin specific peptidase 34 | -0.039562 |
| CALR | calreticulin | -0.0373624 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0357545 |
| CARD16 | caspase recruitment domain family, member 16 | -0.03494 |
| CADM1 | cell adhesion molecule 1 | -0.0347034 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0346593 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0342392 |
| MAP1B | microtubule-associated protein 1B | -0.0341222 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.033519 |
| COG6 | component of oligomeric golgi complex 6 | -0.0334962 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0334894 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0333449 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0326971 |
| NABP1 | nucleic acid binding protein 1 | -0.0321766 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0320079 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0313789 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0312782 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0311662 |
| MAP4 | microtubule-associated protein 4 | -0.0305354 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0304469 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0300371 |
| RNF213 | ring finger protein 213 | -0.0300335 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0297289 |
| CREBBP | CREB binding protein | -0.0293465 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0290902 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0287452 |
| HMGA2 | high mobility group AT-hook 2 | -0.0283816 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0281223 |
| APOL6 | apolipoprotein L, 6 | -0.0278985 |
| ACTG1 | actin gamma 1 | -0.0276723 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0276471 |
| TNRC6B | trinucleotide repeat containing 6B | -0.02721 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0272037 |
| CD109 | CD109 molecule | -0.0271344 |
| TPM1 | tropomyosin 1 (alpha) | -0.0270847 |
| SEPTIN9 | septin 9 | -0.0267531 |
| FNBP4 | formin binding protein 4 | -0.0263138 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0261175 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0260317 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0258316 |
| ARPC3 | actin related protein 2/3 complex, subunit 3, 21kDa | -0.0258017 |
| LOX | lysyl oxidase | -0.0255427 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.025497 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0253117 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0253102 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0252377 |
| PKM | pyruvate kinase, muscle | -0.0250554 |
| CCNI | cyclin I | -0.0247905 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | -0.0245811 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0243239 |
| ZNF148 | zinc finger protein 148 | -0.0243224 |
| UBAP1 | ubiquitin associated protein 1 | -0.0241635 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0239281 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.023913 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0238751 |
| SMYD3 | SET and MYND domain containing 3 | -0.0238264 |
| ATG14 | autophagy related 14 | -0.0237115 |
| RPL23 | ribosomal protein L23 | -0.0235686 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0234941 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0233256 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0233226 |
| TMSB10 | thymosin beta 10 | -0.0233118 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0232205 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | -0.023206 |
| RNF11 | ring finger protein 11 | -0.0231381 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | -0.0231008 |
| KIF2A | kinesin heavy chain member 2A | -0.0230632 |
| BBX | bobby sox homolog (Drosophila) | -0.0230132 |
| APP | amyloid beta (A4) precursor protein | -0.0229397 |
| RTN4 | reticulon 4 | -0.0228982 |
| FOXK1 | forkhead box K1 | -0.0227432 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0226176 |
| RSPRY1 | ring finger and SPRY domain containing 1 | -0.0225985 |
| CD44 | CD44 molecule (Indian blood group) | -0.0225799 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.0224651 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0222992 |
| ECE1 | endothelin converting enzyme 1 | -0.0222444 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.0222042 |
| RPL11 | ribosomal protein L11 | -0.0221967 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0221947 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0221853 |
| FAM234A | family with sequence similarity 234 member A | -0.0221408 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0220655 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0220608 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | -0.021934 |
