| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verteporfin perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Verteporfin_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PODXL | podocalyxin-like | 0.100236 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.066308 |
| SQSTM1 | sequestosome 1 | 0.0611235 |
| LOX | lysyl oxidase | 0.054635 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0499749 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0493213 |
| STC1 | stanniocalcin 1 | 0.0487285 |
| PLAT | plasminogen activator, tissue | 0.048685 |
| HIP1 | huntingtin interacting protein 1 | 0.0467504 |
| MYADM | myeloid-associated differentiation marker | 0.044699 |
| CD99 | CD99 molecule | 0.0435321 |
| LMNA | lamin A/C | 0.0427831 |
| TPM3 | tropomyosin 3 | 0.0377563 |
| LDHA | lactate dehydrogenase A | 0.0372292 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0366035 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0365964 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0354925 |
| SDC4 | syndecan 4 | 0.0342885 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0333305 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0330466 |
| RACK1 | receptor for activated C kinase 1 | 0.0327149 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0321037 |
| FLNA | filamin A, alpha | 0.0306208 |
| CEP350 | centrosomal protein 350kDa | 0.0305173 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0300518 |
| NAV2 | neuron navigator 2 | 0.0298268 |
| MYO9A | myosin IXA | 0.02969 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0294682 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0286784 |
| RPS3 | ribosomal protein S3 | 0.0286539 |
| NDRG1 | N-myc downstream regulated 1 | 0.0283561 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0278428 |
| SEPTIN9 | septin 9 | 0.0271384 |
| C1D | C1D nuclear receptor corepressor | 0.0269886 |
| SVIL | supervillin | 0.0268957 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0268807 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0266445 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0264123 |
| S100A4 | S100 calcium binding protein A4 | 0.0264031 |
| RPS8 | ribosomal protein S8 | 0.0258254 |
| SFTPA2 | surfactant protein A2 | 0.0258121 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0257794 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | 0.0255381 |
| OPTN | optineurin | 0.0253815 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0252716 |
| ANXA4 | annexin A4 | 0.0252208 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0251387 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0251156 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0247857 |
| RC3H1 | ring finger and CCCH-type domains 1 | 0.0243889 |
| HLA-E | major histocompatibility complex, class I, E | 0.0241239 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0240437 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0240347 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0239016 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0237777 |
| TAOK1 | TAO kinase 1 | 0.0236138 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.023341 |
| TAPBP | TAP binding protein (tapasin) | 0.0230552 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0224058 |
| RPS2 | ribosomal protein S2 | 0.0222188 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0221114 |
| GLIS3 | GLIS family zinc finger 3 | 0.0217961 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0217478 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0217032 |
| SOD1 | superoxide dismutase 1, soluble | 0.0216651 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0216642 |
| MEF2D | myocyte enhancer factor 2D | 0.0210836 |
| EFCAB14 | EF-hand calcium binding domain 14 | 0.0208561 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0208342 |
| HMGB2 | high mobility group box 2 | 0.0207433 |
| ARRDC3 | arrestin domain containing 3 | 0.0205646 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0202555 |
| FSD1L | fibronectin type III and SPRY domain containing 1-like | 0.0201473 |
| CALD1 | caldesmon 1 | 0.0200585 |
| FADS2 | fatty acid desaturase 2 | 0.0200313 |
| CLU | clusterin | 0.0199168 |
| PLAUR | plasminogen activator, urokinase receptor | 0.019799 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0195516 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0194536 |
| GSPT1 | G1 to S phase transition 1 | 0.0193677 |
| RAB14 | RAB14, member RAS oncogene family | 0.0192381 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0189174 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0186624 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.018631 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.018549 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0185245 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0184074 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0183474 |
| MNT | MAX network transcriptional repressor | 0.0183181 |
| ANXA2 | annexin A2 | 0.01822 |
| RAB10 | RAB10, member RAS oncogene family | 0.01816 |
| PDGFB | platelet-derived growth factor beta polypeptide | 0.017961 |
| FAM114A1 | family with sequence similarity 114, member A1 | 0.017829 |
| HLA-B | major histocompatibility complex, class I, B | 0.0177298 |
| APP | amyloid beta (A4) precursor protein | 0.0176181 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0175907 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0175776 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0174437 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 0.0173483 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0173253 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.165292 |
| AHNAK | AHNAK nucleoprotein | -0.113314 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.092931 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0863754 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0821056 |
| MEIS2 | Meis homeobox 2 | -0.0806089 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0784312 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0777248 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0770441 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0722244 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0718594 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0696081 |
| DCLK2 | doublecortin-like kinase 2 | -0.0678753 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0634895 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0629443 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0625947 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0622712 |
| MAP1B | microtubule-associated protein 1B | -0.059402 |
| RUNX1 | runt-related transcription factor 1 | -0.0591935 |
| CDH13 | cadherin 13 | -0.0591874 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0570559 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0552307 |
| PTK2 | protein tyrosine kinase 2 | -0.0539252 |
| NAV1 | neuron navigator 1 | -0.0536591 |
| FBN1 | fibrillin 1 | -0.0528028 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0497039 |
| MSI2 | musashi RNA-binding protein 2 | -0.0491995 |
| FN1 | fibronectin 1 | -0.0485414 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0483354 |
| FLNB | filamin B, beta | -0.0481709 |
| RTN4 | reticulon 4 | -0.043544 |
| DST | dystonin | -0.0431659 |
| SETD5 | SET domain containing 5 | -0.0425731 |
| FSTL1 | follistatin-like 1 | -0.042217 |
| MMP12 | matrix metallopeptidase 12 | -0.042022 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0416276 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0410639 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0407554 |
| CANX | calnexin | -0.0403148 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0403038 |
| MT2A | metallothionein 2A | -0.0402627 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0399981 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0379261 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0373434 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0370991 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0363803 |
| CDK6 | cyclin-dependent kinase 6 | -0.0359854 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0358614 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0353126 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0352799 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0351979 |
| FBXO11 | F-box protein 11 | -0.0346665 |
| CSTB | cystatin B (stefin B) | -0.0346115 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0342019 |
| ZNF292 | zinc finger protein 292 | -0.0340281 |
| COL5A1 | collagen, type V, alpha 1 | -0.0340264 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0339219 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.032886 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0328747 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0327272 |
| SUCNR1 | succinate receptor 1 | -0.0325956 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0325672 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0318589 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0314613 |
| XPO1 | exportin 1 | -0.0314151 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0312394 |
| CUX1 | cut-like homeobox 1 | -0.0311576 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0304758 |
| MX2 | MX dynamin-like GTPase 2 | -0.0297358 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0295528 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0292407 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0292363 |
| RAI1 | retinoic acid induced 1 | -0.0292221 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0290969 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0287497 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0284948 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0280319 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0279655 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0278346 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0274861 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0269933 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0269876 |
| FAM13A | family with sequence similarity 13, member A | -0.0268147 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0266709 |
| RAD51B | RAD51 paralog B | -0.026658 |
| ZFR | zinc finger RNA binding protein | -0.0265998 |
| VIM | vimentin | -0.0265857 |
| SBF2 | SET binding factor 2 | -0.0265766 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0265515 |
| FAM107B | family with sequence similarity 107, member B | -0.0265024 |
| MYOF | myoferlin | -0.0265005 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0264383 |
| FMNL2 | formin-like 2 | -0.0262578 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0261824 |
| TMEM123 | transmembrane protein 123 | -0.0257986 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0257974 |
| IER3 | immediate early response 3 | -0.0256494 |
| PRSS23 | protease, serine, 23 | -0.0256304 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0253626 |
| CD47 | CD47 molecule | -0.0247935 |
