| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verteporfin perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Verteporfin_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.0536107 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0474465 |
| KIF5B | kinesin family member 5B | 0.0409793 |
| MKI67 | marker of proliferation Ki-67 | 0.0397074 |
| CENPF | centromere protein F, 350/400kDa | 0.0288935 |
| EDN1 | endothelin 1 | 0.0265803 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0265176 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0233816 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0229023 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0223617 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0221389 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0207199 |
| MTAP | methylthioadenosine phosphorylase | 0.0198791 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0190951 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0183469 |
| EZR | ezrin | 0.0180726 |
| KLF6 | Kruppel-like factor 6 | 0.0159672 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.01462 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0137203 |
| GOLGB1 | golgin B1 | 0.0136326 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.0135668 |
| RPS7 | ribosomal protein S7 | 0.0132871 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0128019 |
| HMGB2 | high mobility group box 2 | 0.0123932 |
| RBM25 | RNA binding motif protein 25 | 0.0120868 |
| ATP11A | ATPase, class VI, type 11A | 0.0119495 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0117313 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0116592 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0106974 |
| TXNRD1 | thioredoxin reductase 1 | 0.0106673 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0105246 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0104188 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0103538 |
| ANXA1 | annexin A1 | 0.0103336 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0102277 |
| SET | SET nuclear proto-oncogene | 0.0101682 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.00976696 |
| DDX27 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | 0.00966058 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.00963899 |
| DSPP | dentin sialophosphoprotein | 0.00958826 |
| INCENP | inner centromere protein antigens 135/155kDa | 0.00957941 |
| CEP95 | centrosomal protein 95kDa | 0.00955231 |
| KIF11 | kinesin family member 11 | 0.00944999 |
| HSPA4 | heat shock 70kDa protein 4 | 0.00942852 |
| EGR1 | early growth response 1 | 0.00938383 |
| PCDH7 | protocadherin 7 | 0.00937774 |
| ZNF146 | zinc finger protein 146 | 0.00911582 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.00907654 |
| AFG3L2 | AFG3-like AAA ATPase 2 | 0.00899084 |
| DKC1 | dyskeratosis congenita 1, dyskerin | 0.00898256 |
| HELB | helicase (DNA) B | 0.00898192 |
| XPC | xeroderma pigmentosum, complementation group C | 0.00893391 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.00882092 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.00880714 |
| TIMELESS | timeless circadian clock | 0.00875305 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.00864081 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00847988 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.00829515 |
| SGCZ | sarcoglycan, zeta | 0.00827349 |
| CENPE | centromere protein E, 312kDa | 0.00825188 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.00822167 |
| BRD8 | bromodomain containing 8 | 0.00819941 |
| GASK1B | golgi associated kinase 1B | 0.00813091 |
| PEG10 | paternally expressed 10 | 0.00798257 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0079122 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.00787748 |
| CCDC88A | coiled-coil domain containing 88A | 0.00783954 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | 0.00780374 |
| H1-4 | H1.4 linker histone, cluster member | 0.00774728 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.00768815 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0076322 |
| TPM3 | tropomyosin 3 | 0.00760767 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.00756358 |
| SMC3 | structural maintenance of chromosomes 3 | 0.00751691 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0074766 |
| CDCA2 | cell division cycle associated 2 | 0.00743962 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.00743189 |
| CLDN1 | claudin 1 | 0.00742992 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00739881 |
| TUBGCP3 | tubulin, gamma complex associated protein 3 | 0.00739048 |
| RAB5B | RAB5B, member RAS oncogene family | 0.00736045 |
| NLN | neurolysin (metallopeptidase M3 family) | 0.00736007 |
| TPX2 | TPX2, microtubule-associated | 0.00728195 |
| PCBP1 | poly(rC) binding protein 1 | 0.00709251 |
| CEP70 | centrosomal protein 70kDa | 0.00709059 |
| SCAMP1 | secretory carrier membrane protein 1 | 0.00704881 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.00704707 |
| NDC80 | NDC80 kinetochore complex component | 0.00704197 |
| CIP2A | cellular inhibitor of PP2A | 0.00702427 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.00694235 |
| PEX13 | peroxisomal biogenesis factor 13 | 0.0069277 |
| CDCA7L | cell division cycle associated 7-like | 0.00689666 |
| SACS | sacsin molecular chaperone | 0.00689323 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.00688079 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00684167 |
| CKAP5 | cytoskeleton associated protein 5 | 0.00677371 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.00668958 |
| CCDC47 | coiled-coil domain containing 47 | 0.00668352 |
| AATF | apoptosis antagonizing transcription factor | 0.00664759 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00662622 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.22806 |
| TMSB10 | thymosin beta 10 | -0.108648 |
| VIM | vimentin | -0.0850038 |
| NLGN1 | neuroligin 1 | -0.0784056 |
| JMJD1C | jumonji domain containing 1C | -0.0507866 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0502651 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0498877 |
| MGAT4C | MGAT4 family, member C | -0.0492657 |
| USP34 | ubiquitin specific peptidase 34 | -0.0442509 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0429769 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0426498 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0414447 |
| FTL | ferritin, light polypeptide | -0.0408378 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0406809 |
| VMP1 | vacuole membrane protein 1 | -0.0383479 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0382395 |
| ACTG1 | actin gamma 1 | -0.0376089 |
| POTEF | POTE ankyrin domain family, member F | -0.036706 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0361021 |
| NF1 | neurofibromin 1 | -0.0347448 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0343637 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0336401 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0327529 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0319377 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0318015 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0317437 |
| TPI1 | triosephosphate isomerase 1 | -0.0310581 |
| SETD5 | SET domain containing 5 | -0.0308955 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0308616 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0305761 |
| ERBIN | erbb2 interacting protein | -0.0303688 |
| MMP12 | matrix metallopeptidase 12 | -0.0302659 |
| NHSL1 | NHS-like 1 | -0.029976 |
| TUBA1B | tubulin, alpha 1b | -0.0296845 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0290298 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0287655 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0286538 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0283395 |
| PTMA | prothymosin, alpha | -0.0283288 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.026938 |
| RASAL2 | RAS protein activator like 2 | -0.0269324 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0266992 |
| PCBP2 | poly(rC) binding protein 2 | -0.02653 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0265035 |
| RPL35A | ribosomal protein L35a | -0.0263911 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0263047 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0262585 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0262449 |
| YAP1 | Yes-associated protein 1 | -0.0262079 |
| RPL19 | ribosomal protein L19 | -0.0258538 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.025819 |
| TFG | TRK-fused gene | -0.0257951 |
| FBXO11 | F-box protein 11 | -0.0257716 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0256584 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0256372 |
| RPLP2 | ribosomal protein, large, P2 | -0.0252009 |
| RTN4 | reticulon 4 | -0.0246564 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0246483 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0245933 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0245478 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0243722 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0243492 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0242573 |
| RPS23 | ribosomal protein S23 | -0.0238623 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0237736 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0235684 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0230499 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0229232 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0228563 |
| MEMO1 | mediator of cell motility 1 | -0.0227103 |
| MED13L | mediator complex subunit 13-like | -0.0225318 |
| UBC | ubiquitin C | -0.0225168 |
| XPO1 | exportin 1 | -0.0225013 |
| SYT1 | synaptotagmin I | -0.0223599 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0219295 |
| DTNA | dystrobrevin, alpha | -0.0219124 |
| RPS15 | ribosomal protein S15 | -0.0217871 |
| GPHN | gephyrin | -0.0215392 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0211119 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.021066 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0208541 |
| RPL8 | ribosomal protein L8 | -0.0207979 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0207777 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0207304 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0206397 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.020635 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0206286 |
| PGK1 | phosphoglycerate kinase 1 | -0.0206176 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.020584 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0205826 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0203955 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0203635 |
| SLC38A2 | solute carrier family 38, member 2 | -0.020358 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0203476 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0201846 |
| CALR | calreticulin | -0.0201471 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0201202 |
| HMGA2 | high mobility group AT-hook 2 | -0.0199781 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0199596 |
| CCNL1 | cyclin L1 | -0.0199263 |
