| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verteporfin perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Verteporfin_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.181262 |
| LPIN1 | lipin 1 | 0.0712288 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0491638 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0324689 |
| RPS6 | ribosomal protein S6 | 0.0321857 |
| CCT3 | chaperonin containing TCP1, subunit 3 (gamma) | 0.0315773 |
| SMAD3 | SMAD family member 3 | 0.0306575 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0291008 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0288524 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0285436 |
| CENPF | centromere protein F, 350/400kDa | 0.0269036 |
| CEP95 | centrosomal protein 95kDa | 0.0258432 |
| ENAH | enabled homolog (Drosophila) | 0.0253627 |
| SLMAP | sarcolemma associated protein | 0.0236441 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0235896 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0234806 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0233447 |
| STC1 | stanniocalcin 1 | 0.0231362 |
| HMGB2 | high mobility group box 2 | 0.023079 |
| GPC5 | glypican 5 | 0.0225945 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0220269 |
| SEPTIN9 | septin 9 | 0.0219068 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0215065 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0214421 |
| PLAT | plasminogen activator, tissue | 0.0212403 |
| CCND1 | cyclin D1 | 0.0211167 |
| MKI67 | marker of proliferation Ki-67 | 0.0208767 |
| IGF2 | insulin-like growth factor 2 | 0.0202962 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.019672 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0194299 |
| CDC27 | cell division cycle 27 | 0.0194286 |
| PCNX2 | pecanex 2 | 0.0192786 |
| TPM3 | tropomyosin 3 | 0.0190632 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0188265 |
| DSTN | destrin (actin depolymerizing factor) | 0.0186182 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0184529 |
| MAP1B | microtubule-associated protein 1B | 0.0184035 |
| RUNX1 | runt-related transcription factor 1 | 0.0183203 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0182622 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0178804 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0178156 |
| ANO6 | anoctamin 6 | 0.0178065 |
| PNN | pinin, desmosome associated protein | 0.0172001 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0171588 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0170935 |
| ITGA11 | integrin, alpha 11 | 0.017048 |
| TRIB2 | tribbles pseudokinase 2 | 0.0170449 |
| HMGA1 | high mobility group AT-hook 1 | 0.0170096 |
| RC3H1 | ring finger and CCCH-type domains 1 | 0.0169841 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | 0.0167595 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0164973 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0164657 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0163062 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.016139 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0161132 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0156054 |
| CAB39 | calcium binding protein 39 | 0.015467 |
| NES | nestin | 0.0154567 |
| KIF23 | kinesin family member 23 | 0.015422 |
| TOGARAM1 | TOG array regulator of axonemal microtubules 1 | 0.0152338 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0152025 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0151453 |
| SET | SET nuclear proto-oncogene | 0.0150782 |
| SRP9 | signal recognition particle 9kDa | 0.0149964 |
| NUP153 | nucleoporin 153kDa | 0.0149159 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0149043 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0148975 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0148665 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0145518 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0143406 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.014202 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0141651 |
| SKA2 | spindle and kinetochore associated complex subunit 2 | 0.0141458 |
| ANGPTL4 | angiopoietin-like 4 | 0.0140927 |
| EIF3J | eukaryotic translation initiation factor 3, subunit J | 0.014052 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0140372 |
| RAB10 | RAB10, member RAS oncogene family | 0.0139361 |
| SPOP | speckle-type POZ protein | 0.0138719 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0138525 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0138232 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0137843 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0137475 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0137372 |
| HPCAL1 | hippocalcin-like 1 | 0.0136453 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0136446 |
| CALU | calumenin | 0.0135914 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0135512 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0135511 |
| PPA1 | pyrophosphatase (inorganic) 1 | 0.0134098 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0133759 |
| ZNF146 | zinc finger protein 146 | 0.0133101 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0133045 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0132668 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0132468 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.01323 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.0130914 |
| CCDC32 | coiled-coil domain containing 32 | 0.0130653 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0130239 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0129894 |
| SDCBP | syndecan binding protein (syntenin) | 0.0129691 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.148851 |
| NRG1 | neuregulin 1 | -0.116407 |
| LSAMP | limbic system-associated membrane protein | -0.112702 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0656185 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0608139 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0576993 |
| TMSB10 | thymosin beta 10 | -0.057481 |
| NDRG1 | N-myc downstream regulated 1 | -0.046638 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0466375 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0449168 |
| VCL | vinculin | -0.0441875 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0439202 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0434164 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0414002 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0405292 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0388837 |
| VIM | vimentin | -0.0373578 |
| RNF213 | ring finger protein 213 | -0.0373299 |
| NREP | neuronal regeneration related protein | -0.0361449 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0351246 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0336136 |
| SYT1 | synaptotagmin I | -0.0328432 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0322807 |
| RPS24 | ribosomal protein S24 | -0.0319177 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0317753 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0307916 |
| RPL34 | ribosomal protein L34 | -0.0307867 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0298455 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0298191 |
| CUX1 | cut-like homeobox 1 | -0.0298052 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0293132 |
| PRKCA | protein kinase C, alpha | -0.0289958 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0289909 |
| AUTS2 | autism susceptibility candidate 2 | -0.0288299 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0286599 |
| TLE4 | transducin-like enhancer of split 4 | -0.0286443 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0285759 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.028407 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0283962 |
| HELZ | helicase with zinc finger | -0.0278157 |
| B2M | beta-2-microglobulin | -0.027315 |
| DGKH | diacylglycerol kinase, eta | -0.027233 |
| SIK2 | salt-inducible kinase 2 | -0.0270869 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0269113 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0266689 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0264268 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0258403 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0254941 |
| SLC38A2 | solute carrier family 38, member 2 | -0.024899 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0243714 |
| CNTN4 | contactin 4 | -0.0240665 |
| MEIS2 | Meis homeobox 2 | -0.0240135 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0239344 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0237532 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0236578 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0235728 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0235019 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0232471 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0230482 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0230416 |
| KLHL13 | kelch-like family member 13 | -0.0229796 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0227575 |
| BBX | bobby sox homolog (Drosophila) | -0.0226072 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.022585 |
| RPL38 | ribosomal protein L38 | -0.0225522 |
| FAM162A | family with sequence similarity 162, member A | -0.0220444 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0218459 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0217436 |
| FTL | ferritin, light polypeptide | -0.0216151 |
| NBEA | neurobeachin | -0.0215617 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0214266 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0213209 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0212741 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0212276 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0212268 |
| BPTF | bromodomain PHD finger transcription factor | -0.0211802 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0211019 |
| GNAS | GNAS complex locus | -0.0210701 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0210638 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0209081 |
| YAP1 | Yes-associated protein 1 | -0.0207619 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0207582 |
| PKM | pyruvate kinase, muscle | -0.0206048 |
| FRMD4A | FERM domain containing 4A | -0.0205875 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0204331 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0202926 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0202872 |
| SMYD3 | SET and MYND domain containing 3 | -0.02023 |
| FLNB | filamin B, beta | -0.0202175 |
| RPL23 | ribosomal protein L23 | -0.0201455 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0201269 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0200862 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0200857 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0199934 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0198517 |
| TMEM123 | transmembrane protein 123 | -0.0197585 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0197518 |
| PLPP1 | phospholipid phosphatase 1 | -0.0196052 |
| GLG1 | golgi glycoprotein 1 | -0.0195829 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0195236 |
