| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verteporfin perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Verteporfin_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0716322 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0686073 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0489819 |
| INTS6 | integrator complex subunit 6 | 0.046527 |
| CCNL1 | cyclin L1 | 0.0410624 |
| EGR1 | early growth response 1 | 0.0410549 |
| SQSTM1 | sequestosome 1 | 0.031205 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0268786 |
| VMP1 | vacuole membrane protein 1 | 0.0259893 |
| PLSCR2 | phospholipid scramblase 2 | 0.0228458 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0202705 |
| TNS4 | tensin 4 | 0.0195534 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0194877 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0186147 |
| DUSP16 | dual specificity phosphatase 16 | 0.0170139 |
| SMAD3 | SMAD family member 3 | 0.0169879 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0168657 |
| SDC4 | syndecan 4 | 0.0165309 |
| LMO7 | LIM domain 7 | 0.0161786 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0158812 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0155058 |
| NPSR1 | neuropeptide S receptor 1 | 0.0151067 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0149043 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0148506 |
| JUN | jun proto-oncogene | 0.0145419 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0143908 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0141254 |
| POU2F2 | POU class 2 homeobox 2 | 0.0137998 |
| MED4 | mediator complex subunit 4 | 0.0134633 |
| PNN | pinin, desmosome associated protein | 0.0132118 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0131492 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0130913 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0129668 |
| NABP1 | nucleic acid binding protein 1 | 0.0127284 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0126771 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0122471 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0117635 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.011587 |
| CPNE4 | copine IV | 0.0115587 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.011387 |
| MCL1 | myeloid cell leukemia 1 | 0.0112925 |
| IER2 | immediate early response 2 | 0.0112739 |
| BTG2 | BTG family, member 2 | 0.0112691 |
| AREG | amphiregulin | 0.0112152 |
| PRSS22 | protease, serine, 22 | 0.0112028 |
| CHD3 | chromodomain helicase DNA binding protein 3 | 0.0109335 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0109124 |
| POF1B | premature ovarian failure, 1B | 0.0108368 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0103833 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0103761 |
| SYT1 | synaptotagmin I | 0.0103177 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0102498 |
| SLC22A23 | solute carrier family 22, member 23 | 0.010236 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.00996374 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.00979542 |
| GPATCH2L | G patch domain containing 2-like | 0.00976816 |
| SLK | STE20-like kinase | 0.00971091 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | 0.00964619 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.00962643 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.00960728 |
| SFPQ | splicing factor proline/glutamine-rich | 0.00957406 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00955189 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.00953278 |
| RAB7A | RAB7A, member RAS oncogene family | 0.00940444 |
| TUT7 | terminal uridylyl transferase 7 | 0.00938218 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00925485 |
| CCP110 | centriolar coiled coil protein 110kDa | 0.00925267 |
| RCOR1 | REST corepressor 1 | 0.00924595 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.00921572 |
| DGKI | diacylglycerol kinase, iota | 0.00920121 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.00911208 |
| CFAP44 | cilia and flagella associated protein 44 | 0.0088965 |
| HOMER1 | homer scaffolding protein 1 | 0.00887924 |
| KYNU | kynureninase | 0.00885323 |
| VEGFA | vascular endothelial growth factor A | 0.0088522 |
| SKIL | SKI-like proto-oncogene | 0.00875634 |
| RND3 | Rho family GTPase 3 | 0.00873495 |
| UBAP2 | ubiquitin associated protein 2 | 0.00860912 |
| TMF1 | TATA element modulatory factor 1 | 0.00859354 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.00855502 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.00847983 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0084667 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.00845193 |
| SH3PXD2A | SH3 and PX domains 2A | 0.00840797 |
| EPHB3 | EPH receptor B3 | 0.00837174 |
| HDGF | hepatoma-derived growth factor | 0.00836258 |
| FOSL2 | FOS-like antigen 2 | 0.00833927 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.00828998 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | 0.00827076 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.00824849 |
| NAV1 | neuron navigator 1 | 0.00823654 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.00817678 |
| EZR | ezrin | 0.00812682 |
| ATP13A3 | ATPase type 13A3 | 0.00811925 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.008111 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.00805216 |
| XDH | xanthine dehydrogenase | 0.00803682 |
| RAB5B | RAB5B, member RAS oncogene family | 0.00796745 |
| RBM4 | RNA binding motif protein 4 | 0.00794852 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.00793771 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.158622 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.154866 |
| B2M | beta-2-microglobulin | -0.124798 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.104664 |
| LCN2 | lipocalin 2 | -0.0822911 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0814188 |
| AHI1 | Abelson helper integration site 1 | -0.0719502 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.065551 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0645949 |
| RUNX1 | runt-related transcription factor 1 | -0.0619251 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0611955 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0597544 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0591569 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.054381 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.054226 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.05347 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0521133 |
| RPL35A | ribosomal protein L35a | -0.0516684 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0497584 |
| PKM | pyruvate kinase, muscle | -0.0497395 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.046689 |
| FTL | ferritin, light polypeptide | -0.0433152 |
| UBC | ubiquitin C | -0.0431801 |
| RNF149 | ring finger protein 149 | -0.0428342 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0423475 |
| XAF1 | XIAP associated factor 1 | -0.0421098 |
| NF1 | neurofibromin 1 | -0.0420938 |
| HLA-B | major histocompatibility complex, class I, B | -0.0420804 |
| TMSB10 | thymosin beta 10 | -0.0417732 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0413559 |
| PGK1 | phosphoglycerate kinase 1 | -0.0394679 |
| RPL34 | ribosomal protein L34 | -0.0391605 |
| ENO1 | enolase 1, (alpha) | -0.0370341 |
| RPL19 | ribosomal protein L19 | -0.0369653 |
| SLC38A1 | solute carrier family 38, member 1 | -0.036938 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0366333 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.036612 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0363903 |
| AHNAK | AHNAK nucleoprotein | -0.0358757 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0358177 |
| H1-0 | H1.0 linker histone | -0.0356629 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0355232 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0354781 |
| RNF213 | ring finger protein 213 | -0.0348112 |
| NDRG1 | N-myc downstream regulated 1 | -0.0347806 |
| PRKCA | protein kinase C, alpha | -0.0346612 |
| RPLP1 | ribosomal protein, large, P1 | -0.0344553 |
| RPS6 | ribosomal protein S6 | -0.0342707 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0340897 |
| MX2 | MX dynamin-like GTPase 2 | -0.0335559 |
| RPL12 | ribosomal protein L12 | -0.0333577 |
| EPCAM | epithelial cell adhesion molecule | -0.033115 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0330203 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0329791 |
| HLA-C | major histocompatibility complex, class I, C | -0.032975 |
| PERP | PERP, TP53 apoptosis effector | -0.0329441 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0328466 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0324527 |
| MATR3 | matrin 3 | -0.032344 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0320238 |
| PTMA | prothymosin, alpha | -0.03198 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0318966 |
| TXNIP | thioredoxin interacting protein | -0.0318837 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0316764 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0316575 |
| RPL11 | ribosomal protein L11 | -0.0316284 |
| PTK2 | protein tyrosine kinase 2 | -0.0314925 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0310433 |
| S100A10 | S100 calcium binding protein A10 | -0.0304852 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0302537 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0298297 |
| RPS8 | ribosomal protein S8 | -0.0298108 |
| PATJ | PATJ crumbs cell polarity complex component | -0.029732 |
| ATXN1 | ataxin 1 | -0.0296704 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0296175 |
| HLA-A | major histocompatibility complex, class I, A | -0.0295613 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0294138 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0292565 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0291576 |
| MSI2 | musashi RNA-binding protein 2 | -0.0287981 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0284978 |
| MYO1E | myosin IE | -0.0283072 |
| RPS24 | ribosomal protein S24 | -0.0282474 |
| RPS19 | ribosomal protein S19 | -0.0282116 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0280971 |
| RPL23 | ribosomal protein L23 | -0.0279222 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0278513 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0269876 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0268699 |
| MAP7 | microtubule-associated protein 7 | -0.0268033 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0266468 |
| RPL26 | ribosomal protein L26 | -0.0266159 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0262458 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0261852 |
| FOXP1 | forkhead box P1 | -0.0259735 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0255475 |
| RPS23 | ribosomal protein S23 | -0.0250802 |
| XPO1 | exportin 1 | -0.0250577 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0250361 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0247425 |
