| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verteporfin perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Verteporfin_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FOXO1 | forkhead box O1 | 0.0792561 |
| EGR1 | early growth response 1 | 0.0621306 |
| PLAT | plasminogen activator, tissue | 0.0565982 |
| MSN | moesin | 0.0532646 |
| LAMC2 | laminin, gamma 2 | 0.0499821 |
| PODXL | podocalyxin-like | 0.0461853 |
| OSMR | oncostatin M receptor | 0.0447019 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0446745 |
| RIN2 | Ras and Rab interactor 2 | 0.0436925 |
| DUSP4 | dual specificity phosphatase 4 | 0.0419814 |
| LUZP1 | leucine zipper protein 1 | 0.0415038 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0401965 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0397291 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0393968 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0387915 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.038695 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0372728 |
| ITGA6 | integrin, alpha 6 | 0.0369063 |
| HLA-B | major histocompatibility complex, class I, B | 0.0366708 |
| BCL2L1 | BCL2-like 1 | 0.0342114 |
| CAPRIN2 | caprin family member 2 | 0.0335452 |
| KIAA0040 | KIAA0040 | 0.0327314 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0305951 |
| PTHLH | parathyroid hormone-like hormone | 0.0299694 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0297497 |
| JAG1 | jagged 1 | 0.0287927 |
| SEPTIN9 | septin 9 | 0.0283254 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0267298 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0267125 |
| ANKRD12 | ankyrin repeat domain 12 | 0.02648 |
| STC1 | stanniocalcin 1 | 0.026162 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0260576 |
| TNS4 | tensin 4 | 0.02565 |
| MCL1 | myeloid cell leukemia 1 | 0.0244993 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0243651 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0242826 |
| VCL | vinculin | 0.0240735 |
| TGM2 | transglutaminase 2 | 0.02395 |
| DOK5 | docking protein 5 | 0.0231916 |
| PLEC | plectin | 0.0218697 |
| VMP1 | vacuole membrane protein 1 | 0.0217969 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0214672 |
| SH3PXD2A | SH3 and PX domains 2A | 0.020615 |
| ASPH | aspartate beta-hydroxylase | 0.0205145 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0203065 |
| CENPF | centromere protein F, 350/400kDa | 0.0201043 |
| MYADM | myeloid-associated differentiation marker | 0.0199163 |
| TPM4 | tropomyosin 4 | 0.019849 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0196895 |
| TPM3 | tropomyosin 3 | 0.0194405 |
| AMOTL1 | angiomotin like 1 | 0.0192919 |
| RAD51B | RAD51 paralog B | 0.0192222 |
| EHF | ets homologous factor | 0.0191722 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0190489 |
| LDLR | low density lipoprotein receptor | 0.0189875 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0187595 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0186104 |
| CD44 | CD44 molecule (Indian blood group) | 0.0185448 |
| FLOT1 | flotillin 1 | 0.0183655 |
| CDCP1 | CUB domain containing protein 1 | 0.0179542 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0178806 |
| SMYD3 | SET and MYND domain containing 3 | 0.0175346 |
| MIDN | midnolin | 0.0172165 |
| LRRC8A | leucine rich repeat containing 8 family, member A | 0.0171846 |
| PDLIM1 | PDZ and LIM domain 1 | 0.0171462 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.016931 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0167543 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0166267 |
| SOX7 | SRY (sex determining region Y)-box 7 | 0.016621 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0163563 |
| FOSL1 | FOS-like antigen 1 | 0.0163376 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0163196 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0162531 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0161338 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0160394 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0159513 |
| TMEM87A | transmembrane protein 87A | 0.01591 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0155689 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0154044 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | 0.0152991 |
| PCDH1 | protocadherin 1 | 0.0152875 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.0152387 |
| AKAP6 | A kinase (PRKA) anchor protein 6 | 0.0150196 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.014893 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0148653 |
| PLXNA2 | plexin A2 | 0.0146025 |
| RBM25 | RNA binding motif protein 25 | 0.0145161 |
| ACTN1 | actinin, alpha 1 | 0.0144944 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0142663 |
| FOXP1 | forkhead box P1 | 0.0142227 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0140972 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0139757 |
| TMC7 | transmembrane channel-like 7 | 0.0139712 |
| PNN | pinin, desmosome associated protein | 0.0138242 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0137507 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0136072 |
| CCNL1 | cyclin L1 | 0.0131482 |
| IER2 | immediate early response 2 | 0.0130897 |
| DCUN1D3 | DCN1, defective in cullin neddylation 1, domain containing 3 | 0.0130272 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.0129734 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | -0.20363 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.12605 |
| FLNB | filamin B, beta | -0.125948 |
| PGK1 | phosphoglycerate kinase 1 | -0.119418 |
| PTMA | prothymosin, alpha | -0.101905 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0888141 |
| ANXA1 | annexin A1 | -0.0826704 |
| MEF2A | myocyte enhancer factor 2A | -0.0796199 |
| GNAS | GNAS complex locus | -0.0743157 |
| TMSB10 | thymosin beta 10 | -0.0732312 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0687732 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0673893 |
| H1-0 | H1.0 linker histone | -0.0669221 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0641411 |
| NAV2 | neuron navigator 2 | -0.0633486 |
| SQLE | squalene epoxidase | -0.0594818 |
| S100A10 | S100 calcium binding protein A10 | -0.0593917 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0591309 |
| MORF4L2 | mortality factor 4 like 2 | -0.0577958 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0575428 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0572773 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0571963 |
| AHNAK | AHNAK nucleoprotein | -0.0564032 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0547877 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0537878 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0534199 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0531983 |
| SPAG9 | sperm associated antigen 9 | -0.0527846 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.051852 |
| KRT17 | keratin 17, type I | -0.0513715 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0507741 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0491713 |
| NDRG1 | N-myc downstream regulated 1 | -0.0485285 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0468404 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0466531 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0459339 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0450144 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.042541 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0417154 |
| SQSTM1 | sequestosome 1 | -0.0415541 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0413601 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0410731 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.040245 |
| COG5 | component of oligomeric golgi complex 5 | -0.0401294 |
| TMSB4X | thymosin beta 4, X-linked | -0.0398358 |
| QKI | QKI, KH domain containing, RNA binding | -0.0384434 |
| FOXO3 | forkhead box O3 | -0.0382655 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0382402 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0381461 |
| RLF | rearranged L-myc fusion | -0.0378949 |
| MYOF | myoferlin | -0.0378223 |
| MT1X | metallothionein 1X | -0.037437 |
| LDHA | lactate dehydrogenase A | -0.0373806 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0369288 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0365499 |
| PTK2 | protein tyrosine kinase 2 | -0.0358549 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0357656 |
| ANLN | anillin, actin binding protein | -0.0357578 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0353816 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0353004 |
| OGA | O-GlcNAcase | -0.0352511 |
| RBM39 | RNA binding motif protein 39 | -0.035111 |
| ENO1 | enolase 1, (alpha) | -0.0350705 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0350669 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0348395 |
| POTEF | POTE ankyrin domain family, member F | -0.034574 |
| SLMAP | sarcolemma associated protein | -0.0336588 |
| LMNA | lamin A/C | -0.0334926 |
| EZR | ezrin | -0.0333912 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0332288 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0331741 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0327948 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0327558 |
| INSIG2 | insulin induced gene 2 | -0.0324393 |
| SBF2 | SET binding factor 2 | -0.0323493 |
| TAGLN2 | transgelin 2 | -0.0322008 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0321354 |
| RNF145 | ring finger protein 145 | -0.032126 |
| RUNX1 | runt-related transcription factor 1 | -0.0317042 |
| SDCBP | syndecan binding protein (syntenin) | -0.0313374 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0312753 |
| RAI14 | retinoic acid induced 14 | -0.0310766 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0309388 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0308804 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0308113 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0304422 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0303763 |
| COPA | coatomer protein complex, subunit alpha | -0.0300335 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0297721 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0297719 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0296555 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0295941 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0295914 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0293847 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0291542 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0286878 |
| PKM | pyruvate kinase, muscle | -0.0286856 |
| HELZ | helicase with zinc finger | -0.0286795 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0281758 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0280295 |
