| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verteporfin perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Verteporfin_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0815772 |
| NDRG1 | N-myc downstream regulated 1 | 0.0648284 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0625427 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0477264 |
| EGR1 | early growth response 1 | 0.0405459 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0369693 |
| FAM13A | family with sequence similarity 13, member A | 0.0336132 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0329293 |
| ARRDC3 | arrestin domain containing 3 | 0.0328367 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0282972 |
| MSN | moesin | 0.0282206 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0264539 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.025275 |
| PCBP2 | poly(rC) binding protein 2 | 0.0241953 |
| STC1 | stanniocalcin 1 | 0.0230815 |
| GOLGA4 | golgin A4 | 0.022375 |
| HYOU1 | hypoxia up-regulated 1 | 0.0215994 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0209583 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0204559 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0202679 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0202029 |
| MCL1 | myeloid cell leukemia 1 | 0.0197173 |
| LAMC2 | laminin, gamma 2 | 0.019692 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0192337 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0188184 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0187291 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0186611 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0183852 |
| RPS6 | ribosomal protein S6 | 0.0178238 |
| MKI67 | marker of proliferation Ki-67 | 0.0175234 |
| ATP13A3 | ATPase type 13A3 | 0.017189 |
| WASF2 | WAS protein family, member 2 | 0.0168502 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0157926 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0157714 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0156498 |
| BRD2 | bromodomain containing 2 | 0.0155965 |
| PNN | pinin, desmosome associated protein | 0.0155399 |
| SRP54 | signal recognition particle 54kDa | 0.0152684 |
| SPAG9 | sperm associated antigen 9 | 0.0151467 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0148905 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0148293 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0147267 |
| CSNK1E | casein kinase 1, epsilon | 0.0143765 |
| NUP58 | nucleoporin 58 | 0.0142841 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0142256 |
| FOSL1 | FOS-like antigen 1 | 0.0141426 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0139319 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0136187 |
| TPM3 | tropomyosin 3 | 0.0134528 |
| HDGF | hepatoma-derived growth factor | 0.013335 |
| CCNL1 | cyclin L1 | 0.0133316 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0132584 |
| RNASEH2A | ribonuclease H2, subunit A | 0.013151 |
| RPS12 | ribosomal protein S12 | 0.0131097 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0129376 |
| SNX9 | sorting nexin 9 | 0.0128708 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0127243 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 | 0.0126685 |
| HMGA1 | high mobility group AT-hook 1 | 0.0126292 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0126262 |
| PTMA | prothymosin, alpha | 0.0126044 |
| NGLY1 | N-glycanase 1 | 0.0125383 |
| RBM25 | RNA binding motif protein 25 | 0.0125257 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0124891 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0123918 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0123606 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0123575 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0122624 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | 0.0122112 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0121978 |
| ATF4 | activating transcription factor 4 | 0.0118209 |
| PCBP1 | poly(rC) binding protein 1 | 0.0117608 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.01173 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0116866 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0116772 |
| SETD5 | SET domain containing 5 | 0.0116747 |
| NR1D1 | nuclear receptor subfamily 1, group D, member 1 | 0.011626 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | 0.011399 |
| ANXA5 | annexin A5 | 0.0113627 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0113552 |
| VIM | vimentin | 0.0113551 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0111985 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0111902 |
| TOM1 | target of myb1 (chicken) | 0.011069 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.010981 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0108761 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0108732 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0107787 |
| INSIG2 | insulin induced gene 2 | 0.010653 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | 0.0105878 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0105567 |
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 | 0.0104975 |
| SMAD4 | SMAD family member 4 | 0.0104725 |
| RNF149 | ring finger protein 149 | 0.0104073 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.010353 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0101365 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0101242 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0101203 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0101063 |
| DUSP5 | dual specificity phosphatase 5 | 0.0100439 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.148713 |
| EGFR | epidermal growth factor receptor | -0.147781 |
| ASPH | aspartate beta-hydroxylase | -0.0917733 |
| LMO7 | LIM domain 7 | -0.0792422 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.072461 |
| TXNRD1 | thioredoxin reductase 1 | -0.0708341 |
| AHNAK | AHNAK nucleoprotein | -0.0605795 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0543037 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0539545 |
| OSMR | oncostatin M receptor | -0.0538905 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0533761 |
| EFNA5 | ephrin-A5 | -0.0504893 |
| H1-0 | H1.0 linker histone | -0.0491863 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0490821 |
| ANXA2 | annexin A2 | -0.0488675 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0474109 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0471199 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0469579 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0456165 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0453031 |
| PGK1 | phosphoglycerate kinase 1 | -0.0448685 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0445737 |
| TMSB10 | thymosin beta 10 | -0.0426578 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0421712 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0407098 |
| SLTM | SAFB-like, transcription modulator | -0.03832 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0379608 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0377765 |
| HDLBP | high density lipoprotein binding protein | -0.0375232 |
| MYOF | myoferlin | -0.0375109 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0355358 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0354963 |
| CANX | calnexin | -0.0351348 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.034995 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0346727 |
| SMYD3 | SET and MYND domain containing 3 | -0.0344851 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0344781 |
| DOCK5 | dedicator of cytokinesis 5 | -0.034316 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0335397 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0335323 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0334021 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.033386 |
| USP34 | ubiquitin specific peptidase 34 | -0.0326179 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.032436 |
| PKM | pyruvate kinase, muscle | -0.0324224 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0322769 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.031768 |
| RNF213 | ring finger protein 213 | -0.0315624 |
| INTS6 | integrator complex subunit 6 | -0.0314742 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0311176 |
| NABP1 | nucleic acid binding protein 1 | -0.0310694 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0309012 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0308044 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0304148 |
| ABLIM1 | actin binding LIM protein 1 | -0.0303606 |
| GM2A | GM2 ganglioside activator | -0.029865 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0296097 |
| RAB10 | RAB10, member RAS oncogene family | -0.0293424 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0291961 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0284221 |
| TES | testin LIM domain protein | -0.0281218 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0279063 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.027556 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0271028 |
| RPS24 | ribosomal protein S24 | -0.0269395 |
| HBP1 | HMG-box transcription factor 1 | -0.0268239 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0265819 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0265628 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0265044 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0265031 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0260492 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0258033 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0257893 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0253312 |
| FOXP1 | forkhead box P1 | -0.0250786 |
| AGO2 | argonaute RISC catalytic component 2 | -0.024925 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0247867 |
| RPL35A | ribosomal protein L35a | -0.0246481 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0246104 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0244285 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0243384 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0242703 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0239275 |
| UBC | ubiquitin C | -0.0237905 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0237869 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0235815 |
| VCL | vinculin | -0.0235617 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0234764 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.02329 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.0232403 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.02319 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0231174 |
| SUMF1 | sulfatase modifying factor 1 | -0.0230742 |
| LRP12 | low density lipoprotein receptor-related protein 12 | -0.0229016 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0228708 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0226093 |
| GRAMD1B | GRAM domain containing 1B | -0.0223741 |
| ACTG1 | actin gamma 1 | -0.0223382 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0222144 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0221896 |