| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verteporfin perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Verteporfin_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.16089 |
| GRAMD1B | GRAM domain containing 1B | 0.149699 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.114129 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.100543 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0990517 |
| VIM | vimentin | 0.0681505 |
| CENPF | centromere protein F, 350/400kDa | 0.0533525 |
| TPM3 | tropomyosin 3 | 0.0527866 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0498764 |
| HDGF | hepatoma-derived growth factor | 0.0470375 |
| RPS12 | ribosomal protein S12 | 0.0459004 |
| EGR1 | early growth response 1 | 0.0454667 |
| HDAC9 | histone deacetylase 9 | 0.0424887 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0423074 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0417007 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0412261 |
| LDHA | lactate dehydrogenase A | 0.0400661 |
| KIF5B | kinesin family member 5B | 0.0396031 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.039471 |
| PNN | pinin, desmosome associated protein | 0.0394374 |
| FGB | fibrinogen beta chain | 0.0386121 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.037718 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.036221 |
| MKI67 | marker of proliferation Ki-67 | 0.0355897 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.035127 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0344299 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0335817 |
| MSN | moesin | 0.0329634 |
| RPL26 | ribosomal protein L26 | 0.0316855 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0314473 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0312295 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0307553 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0306983 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0298435 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0291541 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0290027 |
| PYGL | phosphorylase, glycogen, liver | 0.0286839 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0284708 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0273383 |
| PCBP1 | poly(rC) binding protein 1 | 0.0272981 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0265384 |
| TPM4 | tropomyosin 4 | 0.026443 |
| GOLGA4 | golgin A4 | 0.0256386 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0255265 |
| RPL37 | ribosomal protein L37 | 0.0253402 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0249015 |
| ATF4 | activating transcription factor 4 | 0.02478 |
| RPS17 | ribosomal protein S17 | 0.0243144 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0240704 |
| RACK1 | receptor for activated C kinase 1 | 0.0240144 |
| ITGA6 | integrin, alpha 6 | 0.0238554 |
| STC1 | stanniocalcin 1 | 0.0237891 |
| HMGA1 | high mobility group AT-hook 1 | 0.0237703 |
| RPS2 | ribosomal protein S2 | 0.0232822 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0232703 |
| LAMB1 | laminin, beta 1 | 0.0227394 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.022642 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0222056 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0221225 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0213338 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0213174 |
| OSMR | oncostatin M receptor | 0.0213094 |
| AKAP17A | A kinase (PRKA) anchor protein 17A | 0.0208872 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0207043 |
| VMP1 | vacuole membrane protein 1 | 0.0204617 |
| UBXN4 | UBX domain protein 4 | 0.0204253 |
| AURKA | aurora kinase A | 0.0203992 |
| MYADM | myeloid-associated differentiation marker | 0.019941 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0196326 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.019434 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0192845 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0191592 |
| SFSWAP | splicing factor, suppressor of white-apricot family | 0.0186812 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.018502 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0183805 |
| TGFB2 | transforming growth factor, beta 2 | 0.0181682 |
| DDX27 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | 0.0180671 |
| BRD2 | bromodomain containing 2 | 0.0180575 |
| EGFR | epidermal growth factor receptor | 0.0180379 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0179862 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0179103 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0178895 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0177721 |
| RBM8A | RNA binding motif protein 8A | 0.0176925 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0175726 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0173963 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0173481 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.017345 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.017229 |
| YBX1 | Y box binding protein 1 | 0.0172016 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0170432 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0170086 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0168983 |
| USP36 | ubiquitin specific peptidase 36 | 0.0168274 |
| USP8 | ubiquitin specific peptidase 8 | 0.0165851 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0165816 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0164629 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0162609 |
| CENPE | centromere protein E, 312kDa | 0.0160161 |
| FLNA | filamin A, alpha | 0.0159997 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.255442 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.17351 |
| PARD3 | par-3 family cell polarity regulator | -0.162623 |
| FTL | ferritin, light polypeptide | -0.142304 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.106849 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.106098 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0842497 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0801679 |
| TMSB10 | thymosin beta 10 | -0.077251 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.077158 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0752742 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0740874 |
| RPL19 | ribosomal protein L19 | -0.0698846 |
| IER3 | immediate early response 3 | -0.0662665 |
| FMNL2 | formin-like 2 | -0.0653205 |
| AHNAK | AHNAK nucleoprotein | -0.0603367 |
| S100A10 | S100 calcium binding protein A10 | -0.0588034 |
| USP3 | ubiquitin specific peptidase 3 | -0.0564258 |
| TXNRD1 | thioredoxin reductase 1 | -0.0549775 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0546569 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0528265 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0518944 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0515074 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0495976 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0493601 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0491301 |
| TPD52 | tumor protein D52 | -0.0488 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0470781 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0453752 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0452565 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0444906 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0442034 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0434552 |
| FUS | FUS RNA binding protein | -0.0430876 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0408286 |
| FNDC3B | fibronectin type III domain containing 3B | -0.040611 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0405891 |
| MT2A | metallothionein 2A | -0.0401548 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0397121 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0394985 |
| RPLP0 | ribosomal protein, large, P0 | -0.0383253 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0381283 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0378655 |
| PTK2 | protein tyrosine kinase 2 | -0.037727 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0370597 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0369551 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | -0.0364335 |
| COG5 | component of oligomeric golgi complex 5 | -0.0362477 |
| RPS15 | ribosomal protein S15 | -0.0362427 |
| APP | amyloid beta (A4) precursor protein | -0.0361798 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0354049 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0350255 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0347793 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0347516 |
| TNPO1 | transportin 1 | -0.034476 |
| FNBP1L | formin binding protein 1-like | -0.0344689 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0343662 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0340972 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0338633 |
| CCNY | cyclin Y | -0.0338509 |
| NEK7 | NIMA-related kinase 7 | -0.0330263 |
| ENAH | enabled homolog (Drosophila) | -0.0329056 |
| RPS5 | ribosomal protein S5 | -0.0328461 |
| RPL8 | ribosomal protein L8 | -0.0324784 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0318206 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0315395 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0314117 |
| H1-0 | H1.0 linker histone | -0.031281 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0311791 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0311618 |
| CHN1 | chimerin 1 | -0.0308386 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0307459 |
| ANXA2 | annexin A2 | -0.0305735 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0301122 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0300943 |
| FTO | fat mass and obesity associated | -0.0300483 |
| ECT2 | epithelial cell transforming 2 | -0.0300481 |
| PRR16 | proline rich 16 | -0.0299764 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0297186 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0293783 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | -0.0290358 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0289481 |
| RLF | rearranged L-myc fusion | -0.0289292 |
| RPS21 | ribosomal protein S21 | -0.028867 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0288291 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0288269 |
| SETD5 | SET domain containing 5 | -0.0286622 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0283588 |
| RHEB | Ras homolog enriched in brain | -0.0278505 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.027523 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0274776 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0273818 |
| RPS24 | ribosomal protein S24 | -0.0272805 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0272471 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0271183 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0269108 |
| WWOX | WW domain containing oxidoreductase | -0.0267296 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0265492 |
| ACTG1 | actin gamma 1 | -0.0263187 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0262192 |
