| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verteporfin perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Verteporfin_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.112329 |
| PTMA | prothymosin, alpha | 0.112287 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0895466 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0820902 |
| MT2A | metallothionein 2A | 0.0804708 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0740519 |
| VIM | vimentin | 0.0631155 |
| TPR | translocated promoter region, nuclear basket protein | 0.0555975 |
| ANXA5 | annexin A5 | 0.0480037 |
| RPL31 | ribosomal protein L31 | 0.0479298 |
| RPS3 | ribosomal protein S3 | 0.0478647 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0452528 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0447914 |
| RPLP2 | ribosomal protein, large, P2 | 0.0447492 |
| TMSB10 | thymosin beta 10 | 0.0447138 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0445287 |
| PHF21A | PHD finger protein 21A | 0.0437864 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0425781 |
| RBM39 | RNA binding motif protein 39 | 0.0415701 |
| PDE10A | phosphodiesterase 10A | 0.0411391 |
| GOLGB1 | golgin B1 | 0.0395876 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0389193 |
| SEC24D | SEC24 family member D | 0.0379618 |
| RPL36A | ribosomal protein L36a | 0.0374235 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0363443 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0362985 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0362814 |
| RPS6 | ribosomal protein S6 | 0.0355492 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0347294 |
| CMIP | c-Maf inducing protein | 0.0347099 |
| CDH13 | cadherin 13 | 0.0346745 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0343651 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0340903 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0336648 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0334038 |
| SEPTIN2 | septin 2 | 0.0333118 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0331888 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0329303 |
| TAOK1 | TAO kinase 1 | 0.032577 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0323094 |
| SYT1 | synaptotagmin I | 0.0319764 |
| BMERB1 | bMERB domain containing 1 | 0.031735 |
| RAD51B | RAD51 paralog B | 0.0316608 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0314461 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0313437 |
| RPL37 | ribosomal protein L37 | 0.0310182 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0310131 |
| CCDC93 | coiled-coil domain containing 93 | 0.0309502 |
| ENAH | enabled homolog (Drosophila) | 0.0308225 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0307711 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0304471 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0304031 |
| RPL9 | ribosomal protein L9 | 0.0302646 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0302529 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0300878 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.030058 |
| NEBL | nebulette | 0.0299601 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0298328 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0292656 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0292353 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0291877 |
| DHDDS | dehydrodolichyl diphosphate synthase | 0.0290797 |
| TMF1 | TATA element modulatory factor 1 | 0.0288246 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0286081 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0285042 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0282528 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0282293 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0278878 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0278047 |
| STK24 | serine/threonine kinase 24 | 0.0276454 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0274089 |
| COG5 | component of oligomeric golgi complex 5 | 0.0273789 |
| GOLGA2 | golgin A2 | 0.0273083 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0272921 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0271847 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0270885 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0270879 |
| TOP1 | topoisomerase (DNA) I | 0.027038 |
| FBXO42 | F-box protein 42 | 0.0268244 |
| KIAA1217 | KIAA1217 | 0.026701 |
| FAM13A | family with sequence similarity 13, member A | 0.0266762 |
| SLC25A2 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 | 0.0266189 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0265309 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0265289 |
| TPD52 | tumor protein D52 | 0.0265279 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0262912 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0262833 |
| UBE3A | ubiquitin protein ligase E3A | 0.0262724 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | 0.0262608 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0262178 |
| GDNF | glial cell derived neurotrophic factor | 0.0261975 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0261731 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.026078 |
| BRD2 | bromodomain containing 2 | 0.0259873 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0259662 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0259361 |
| RPS19 | ribosomal protein S19 | 0.0259354 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0259226 |
| MSN | moesin | 0.0258649 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0258052 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.174125 |
| LMO7 | LIM domain 7 | -0.150348 |
| MYO1E | myosin IE | -0.132508 |
| LAMB3 | laminin, beta 3 | -0.113035 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.111059 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.101651 |
| ATOSA | atos homolog A | -0.0981711 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0967025 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.090504 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0885946 |
| EGFR | epidermal growth factor receptor | -0.0853321 |
| LAMC2 | laminin, gamma 2 | -0.0849299 |
| TXNRD1 | thioredoxin reductase 1 | -0.0775152 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0743367 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0736741 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0701951 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0685538 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0655011 |
| ABHD17C | abhydrolase domain containing 17C | -0.0626929 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.060197 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0598514 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0595773 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0568725 |
| ERBIN | erbb2 interacting protein | -0.0563721 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.054576 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0536017 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0509069 |
| SVIL | supervillin | -0.0495828 |
| OSMR | oncostatin M receptor | -0.0479808 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0472584 |
| JMJD1C | jumonji domain containing 1C | -0.0444461 |
| POTEF | POTE ankyrin domain family, member F | -0.0430989 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0428537 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0425351 |
| ACTG1 | actin gamma 1 | -0.0415887 |
| VCL | vinculin | -0.0413051 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0409092 |
| ANXA11 | annexin A11 | -0.0408732 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0407861 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0400144 |
| KRT17 | keratin 17, type I | -0.0386804 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.038524 |
| RAB10 | RAB10, member RAS oncogene family | -0.0385072 |
| ANTXR2 | anthrax toxin receptor 2 | -0.038388 |
| RPL35A | ribosomal protein L35a | -0.0375022 |
| INHBA | inhibin, beta A | -0.0372311 |
| ZNF644 | zinc finger protein 644 | -0.036881 |
| EMP1 | epithelial membrane protein 1 | -0.0368574 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0367305 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0364009 |
| AHNAK | AHNAK nucleoprotein | -0.0362793 |
| RBM47 | RNA binding motif protein 47 | -0.0362672 |
| PKM | pyruvate kinase, muscle | -0.0344146 |
| KYNU | kynureninase | -0.034409 |
| MED13 | mediator complex subunit 13 | -0.0344004 |
| TJP1 | tight junction protein 1 | -0.0343329 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.034241 |
| S100A10 | S100 calcium binding protein A10 | -0.0340349 |
| ABI1 | abl-interactor 1 | -0.0336424 |
| FAM107B | family with sequence similarity 107, member B | -0.0334751 |
| MXD1 | MAX dimerization protein 1 | -0.0332848 |
| THRB | thyroid hormone receptor, beta | -0.0332135 |
| RAI14 | retinoic acid induced 14 | -0.0330863 |
| FBXO11 | F-box protein 11 | -0.0330214 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0329425 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0328569 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0327937 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | -0.0322394 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0320988 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0318982 |
| RNF213 | ring finger protein 213 | -0.0316594 |
| TJP2 | tight junction protein 2 | -0.0314946 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0313737 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0311133 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0309073 |
| BBX | bobby sox homolog (Drosophila) | -0.0308074 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0306961 |
| GRAMD2B | GRAM domain containing 2B | -0.0305716 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0304855 |
| PTK2 | protein tyrosine kinase 2 | -0.0304598 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0300919 |
| XPO1 | exportin 1 | -0.030035 |
| SPIRE1 | spire-type actin nucleation factor 1 | -0.0300161 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0299772 |
| KAT6A | K(lysine) acetyltransferase 6A | -0.0299555 |
| NPTN | neuroplastin | -0.0299036 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0297505 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0294355 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0292583 |
| DENND2C | DENN/MADD domain containing 2C | -0.0287719 |
| UBC | ubiquitin C | -0.0285844 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0284314 |
| MYO5B | myosin VB | -0.0278139 |
| S100A9 | S100 calcium binding protein A9 | -0.0278129 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0278043 |
| DIAPH1 | diaphanous-related formin 1 | -0.0275187 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0273613 |
| MYO6 | myosin VI | -0.0273103 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0271789 |
| PSEN1 | presenilin 1 | -0.0270814 |
