| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verteporfin perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Verteporfin_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.194323 |
| EGR1 | early growth response 1 | 0.077073 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0489274 |
| HMGA2 | high mobility group AT-hook 2 | 0.040838 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0382938 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0355336 |
| VIM | vimentin | 0.0351279 |
| PDE10A | phosphodiesterase 10A | 0.0328136 |
| KLF6 | Kruppel-like factor 6 | 0.0314236 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.029282 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0279305 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0277554 |
| OSMR | oncostatin M receptor | 0.0247026 |
| PCBP1 | poly(rC) binding protein 1 | 0.0233711 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0225748 |
| HLA-B | major histocompatibility complex, class I, B | 0.0224807 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.020473 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0203322 |
| RYR3 | ryanodine receptor 3 | 0.0201526 |
| STC1 | stanniocalcin 1 | 0.0200399 |
| PFN1 | profilin 1 | 0.0196889 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0190406 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0190069 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0188094 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0184633 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0182772 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0181265 |
| LATS2 | large tumor suppressor kinase 2 | 0.017429 |
| LOXL2 | lysyl oxidase-like 2 | 0.0174264 |
| EGFR | epidermal growth factor receptor | 0.0173745 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0167817 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.0167503 |
| TCIM | transcriptional and immune response regulator | 0.0167062 |
| JUN | jun proto-oncogene | 0.0166821 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0165492 |
| CLDN1 | claudin 1 | 0.0164781 |
| MYADM | myeloid-associated differentiation marker | 0.0163877 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0162279 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0161089 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0160676 |
| PTMS | parathymosin | 0.0159056 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0155932 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0153841 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0146098 |
| HMGA1 | high mobility group AT-hook 1 | 0.014238 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0142127 |
| TPM4 | tropomyosin 4 | 0.0141481 |
| MCL1 | myeloid cell leukemia 1 | 0.0139932 |
| GRAMD1B | GRAM domain containing 1B | 0.0138973 |
| VCL | vinculin | 0.0137244 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0136313 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0132714 |
| CCND1 | cyclin D1 | 0.0132403 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0128154 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0127901 |
| SMAD3 | SMAD family member 3 | 0.0124491 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0123266 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0122713 |
| RPL23 | ribosomal protein L23 | 0.0121442 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.012112 |
| COL5A2 | collagen, type V, alpha 2 | 0.011732 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0116991 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0114707 |
| SMIM44 | small integral membrane protein 44 | 0.0112323 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0110804 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.011055 |
| CDCP1 | CUB domain containing protein 1 | 0.011048 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0110321 |
| FNDC3B | fibronectin type III domain containing 3B | 0.01097 |
| FAM13A | family with sequence similarity 13, member A | 0.0108954 |
| RNF213 | ring finger protein 213 | 0.0107861 |
| IER2 | immediate early response 2 | 0.010737 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) | 0.0107274 |
| RAB5B | RAB5B, member RAS oncogene family | 0.0106378 |
| TMSB10 | thymosin beta 10 | 0.0105872 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0104881 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0104749 |
| BNC2 | basonuclin 2 | 0.0102909 |
| TAPBP | TAP binding protein (tapasin) | 0.0102643 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.010238 |
| CUX1 | cut-like homeobox 1 | 0.010196 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0100544 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0100431 |
| VASP | vasodilator-stimulated phosphoprotein | 0.00975341 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.00964894 |
| WWOX | WW domain containing oxidoreductase | 0.00964461 |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 | 0.0095733 |
| HDGF | hepatoma-derived growth factor | 0.00950539 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.00946217 |
| BCAP29 | B-cell receptor-associated protein 29 | 0.00942781 |
| STC2 | stanniocalcin 2 | 0.00938652 |
| SVIL | supervillin | 0.00931656 |
| LDHA | lactate dehydrogenase A | 0.0093151 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.00929066 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00916417 |
| NPAS2 | neuronal PAS domain protein 2 | 0.00886374 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | 0.00886273 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.00878866 |
| IGF2 | insulin-like growth factor 2 | 0.00872754 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.00871613 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | -0.179144 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.151071 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.11243 |
| TXNRD1 | thioredoxin reductase 1 | -0.0970928 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0883472 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0803969 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0763201 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0644649 |
| RTN4 | reticulon 4 | -0.0634048 |
| GPHN | gephyrin | -0.0625642 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0613816 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0592404 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0592263 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0573971 |
| XPO1 | exportin 1 | -0.0572658 |
| YBX3 | Y box binding protein 3 | -0.0561582 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0561278 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0558982 |
| FBXO11 | F-box protein 11 | -0.0545604 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0543891 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.054379 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0535241 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0531358 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0530077 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0524891 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.051836 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0514204 |
| OGA | O-GlcNAcase | -0.0503221 |
| PHIP | pleckstrin homology domain interacting protein | -0.0497796 |
| BBX | bobby sox homolog (Drosophila) | -0.0496429 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0488766 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0483375 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0472326 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0454951 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0454019 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0444966 |
| ADAR | adenosine deaminase, RNA-specific | -0.0443646 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0437146 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.043379 |
| RAD51B | RAD51 paralog B | -0.0430341 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0427277 |
| STK4 | serine/threonine kinase 4 | -0.0424573 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0422702 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0414076 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0411173 |
| MED13L | mediator complex subunit 13-like | -0.0406161 |
| SPAG9 | sperm associated antigen 9 | -0.0405182 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0403829 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0396684 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0386324 |
| CLTC | clathrin, heavy chain (Hc) | -0.0381753 |
| TPI1 | triosephosphate isomerase 1 | -0.0374992 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0370802 |
| UBC | ubiquitin C | -0.036708 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0366844 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0357567 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0351944 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0349561 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.034815 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0344695 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0342788 |
| SRPK1 | SRSF protein kinase 1 | -0.0342139 |
| PGK1 | phosphoglycerate kinase 1 | -0.0341699 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0341474 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0340195 |
| EXOC6B | exocyst complex component 6B | -0.0338671 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0336903 |
| EXOC4 | exocyst complex component 4 | -0.033629 |
| CCND2 | cyclin D2 | -0.0333911 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0329512 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0328994 |
| ZNF638 | zinc finger protein 638 | -0.0328647 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0326623 |
| PPME1 | protein phosphatase methylesterase 1 | -0.03252 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0324494 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0324445 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0324095 |
| PCNX1 | pecanex 1 | -0.0323759 |
| ATXN2 | ataxin 2 | -0.0322868 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0322795 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0319921 |
| OLA1 | Obg-like ATPase 1 | -0.0317194 |
| HELZ | helicase with zinc finger | -0.0310738 |
| RHEB | Ras homolog enriched in brain | -0.0310039 |
| NF1 | neurofibromin 1 | -0.0309289 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0307547 |
| GOLGA4 | golgin A4 | -0.0305717 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0305636 |
| RPL19 | ribosomal protein L19 | -0.0305483 |
| CEP192 | centrosomal protein 192kDa | -0.0305414 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0303555 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | -0.0303441 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0302466 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0302092 |
| SEPTIN7 | septin 7 | -0.0301648 |
| PTMA | prothymosin, alpha | -0.0299306 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0298439 |
| RPS10 | ribosomal protein S10 | -0.0297158 |
| JMJD1C | jumonji domain containing 1C | -0.0296986 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0295381 |
