| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verteporfin perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Verteporfin_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.171852 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.122015 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.108614 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0838649 |
| FTL | ferritin, light polypeptide | 0.081449 |
| HMGA1 | high mobility group AT-hook 1 | 0.0682715 |
| PTMA | prothymosin, alpha | 0.0668848 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.065113 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0585556 |
| TPM3 | tropomyosin 3 | 0.0550788 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.050333 |
| RBM25 | RNA binding motif protein 25 | 0.0483279 |
| RPS6 | ribosomal protein S6 | 0.0440669 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0432941 |
| GOLGA4 | golgin A4 | 0.0389098 |
| RPS8 | ribosomal protein S8 | 0.0368254 |
| TMF1 | TATA element modulatory factor 1 | 0.0362202 |
| CALR | calreticulin | 0.035466 |
| MSN | moesin | 0.0344978 |
| HDGF | hepatoma-derived growth factor | 0.0341688 |
| VEGFA | vascular endothelial growth factor A | 0.0337779 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0335396 |
| VIM | vimentin | 0.0331233 |
| POTEF | POTE ankyrin domain family, member F | 0.0318335 |
| MT2A | metallothionein 2A | 0.0300832 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0293294 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0291447 |
| DSTN | destrin (actin depolymerizing factor) | 0.0289536 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0286825 |
| RPLP1 | ribosomal protein, large, P1 | 0.0286355 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0282006 |
| SET | SET nuclear proto-oncogene | 0.0279165 |
| LDHA | lactate dehydrogenase A | 0.0274608 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0273884 |
| PNN | pinin, desmosome associated protein | 0.027132 |
| RACK1 | receptor for activated C kinase 1 | 0.0266321 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0265528 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.026443 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0263248 |
| YBX1 | Y box binding protein 1 | 0.0263228 |
| RPS12 | ribosomal protein S12 | 0.0247297 |
| HMGB2 | high mobility group box 2 | 0.0239554 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.023883 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0237555 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0211662 |
| CTSS | cathepsin S | 0.0206407 |
| SDC4 | syndecan 4 | 0.0203298 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0203014 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0200326 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0200091 |
| RPL37A | ribosomal protein L37a | 0.0199632 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.019365 |
| RPL36 | ribosomal protein L36 | 0.0190523 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0190098 |
| CLDN4 | claudin 4 | 0.0184654 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0181008 |
| CENPF | centromere protein F, 350/400kDa | 0.0180913 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | 0.0180559 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0179656 |
| PCBP1 | poly(rC) binding protein 1 | 0.0178456 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0174214 |
| SRP54 | signal recognition particle 54kDa | 0.0172202 |
| TPM4 | tropomyosin 4 | 0.0170382 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0170047 |
| BRD2 | bromodomain containing 2 | 0.0169854 |
| MKI67 | marker of proliferation Ki-67 | 0.0169243 |
| RPS3 | ribosomal protein S3 | 0.0169035 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0167956 |
| MUC1 | mucin 1, cell surface associated | 0.0166969 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.016682 |
| RPL26 | ribosomal protein L26 | 0.0166686 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.0161723 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0160604 |
| RPL18 | ribosomal protein L18 | 0.0160205 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0159455 |
| ATF4 | activating transcription factor 4 | 0.0158468 |
| ANXA1 | annexin A1 | 0.0158047 |
| RPL21 | ribosomal protein L21 | 0.0157694 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0157344 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0156699 |
| RPS2 | ribosomal protein S2 | 0.0156543 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0155338 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0154233 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0153398 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0153065 |
| FYTTD1 | forty-two-three domain containing 1 | 0.015224 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0150886 |
| GGNBP2 | gametogenetin binding protein 2 | 0.0150159 |
| OPTN | optineurin | 0.0149789 |
| RPS19 | ribosomal protein S19 | 0.0149453 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0148886 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0148356 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0147801 |
| RPS17 | ribosomal protein S17 | 0.0147422 |
| RNF145 | ring finger protein 145 | 0.0146998 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.014425 |
| PFN1 | profilin 1 | 0.0143425 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0143284 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0143081 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0141135 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.204668 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.192424 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.132109 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0982225 |
| AHNAK | AHNAK nucleoprotein | -0.0944811 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0888752 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0878101 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0865458 |
| LMO7 | LIM domain 7 | -0.0821273 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0729729 |
| PTK2 | protein tyrosine kinase 2 | -0.0724355 |
| CD2AP | CD2-associated protein | -0.0661073 |
| EFNA5 | ephrin-A5 | -0.0635666 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0602357 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0581936 |
| NAV2 | neuron navigator 2 | -0.0550336 |
| ANXA2 | annexin A2 | -0.0550058 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0545691 |
| PGK1 | phosphoglycerate kinase 1 | -0.0538773 |
| UBC | ubiquitin C | -0.0530812 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0529338 |
| SQSTM1 | sequestosome 1 | -0.0514311 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0500193 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.049651 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0496411 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0484394 |
| ERBIN | erbb2 interacting protein | -0.0476205 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0473499 |
| ASPH | aspartate beta-hydroxylase | -0.0460902 |
| TMSB10 | thymosin beta 10 | -0.0453152 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0453055 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0452431 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0440618 |
| SMAD3 | SMAD family member 3 | -0.0418618 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0416801 |
| S100A10 | S100 calcium binding protein A10 | -0.0414893 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0398865 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0398652 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0397664 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0394041 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0391092 |
| TMEM263 | transmembrane protein 263 | -0.038594 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0376204 |
| RUNX1 | runt-related transcription factor 1 | -0.0375869 |
| FLNB | filamin B, beta | -0.0375398 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0369206 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0363735 |
| LAMC2 | laminin, gamma 2 | -0.0356629 |
| RPS24 | ribosomal protein S24 | -0.0353209 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0352072 |
| TMSB4X | thymosin beta 4, X-linked | -0.0347937 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0345321 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0337586 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0333973 |
| USP3 | ubiquitin specific peptidase 3 | -0.0333052 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.032763 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0320684 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0320187 |
| KRT7 | keratin 7, type II | -0.0318091 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0316222 |
| KRT8 | keratin 8, type II | -0.0315365 |
| ENO1 | enolase 1, (alpha) | -0.0314904 |
| CDK17 | cyclin-dependent kinase 17 | -0.0314434 |
| CYRIB | CYFIP related Rac1 interactor B | -0.031399 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0310289 |
| MEF2A | myocyte enhancer factor 2A | -0.0308922 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.030643 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0304514 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0302404 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0301601 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0301073 |
| FAM162A | family with sequence similarity 162, member A | -0.0300197 |
| CDCP1 | CUB domain containing protein 1 | -0.0296782 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0293837 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0289046 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0288992 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0287274 |
| MAP4 | microtubule-associated protein 4 | -0.0283707 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0282641 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0282096 |
| SYT1 | synaptotagmin I | -0.0280847 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0279605 |
| CDC73 | cell division cycle 73 | -0.0279181 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0276126 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0272747 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0272365 |
| NEK7 | NIMA-related kinase 7 | -0.0269541 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0268661 |
| PKM | pyruvate kinase, muscle | -0.0266892 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0264907 |
| RPL32 | ribosomal protein L32 | -0.0262137 |
| VCL | vinculin | -0.0260834 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0249741 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0248084 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0246109 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0245862 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0245777 |
| RPL8 | ribosomal protein L8 | -0.0244678 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0243565 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0243508 |
