| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verteporfin perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Verteporfin_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.16065 |
| ASPH | aspartate beta-hydroxylase | 0.121844 |
| PM20D1 | peptidase M20 domain containing 1 | 0.117858 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.105664 |
| DST | dystonin | 0.104453 |
| GDA | guanine deaminase | 0.103238 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0812759 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0798746 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0782012 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0778955 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0758936 |
| COL5A2 | collagen, type V, alpha 2 | 0.073133 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0704114 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.068331 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0649745 |
| CENPF | centromere protein F, 350/400kDa | 0.0632215 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0628755 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.061539 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0602455 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0596269 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0591564 |
| GRAMD1B | GRAM domain containing 1B | 0.0585625 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0572176 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0539114 |
| MKI67 | marker of proliferation Ki-67 | 0.0538939 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0537205 |
| RGS2 | regulator of G-protein signaling 2 | 0.0528664 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0528276 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0523074 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0504372 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0479085 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0453947 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0440105 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0435771 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0435698 |
| CTSC | cathepsin C | 0.0432841 |
| EGR1 | early growth response 1 | 0.0431231 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0429406 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0426737 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0426251 |
| KYNU | kynureninase | 0.042364 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0413813 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0405252 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0401508 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0395018 |
| RBM39 | RNA binding motif protein 39 | 0.0388353 |
| VCL | vinculin | 0.03882 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0378408 |
| ATAD1 | ATPase family, AAA domain containing 1 | 0.0375986 |
| NRCAM | neuronal cell adhesion molecule | 0.037294 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0370171 |
| MCL1 | myeloid cell leukemia 1 | 0.0362441 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0357825 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0350057 |
| RPS6 | ribosomal protein S6 | 0.0349682 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0345584 |
| TPM3 | tropomyosin 3 | 0.0345319 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0343009 |
| PTMA | prothymosin, alpha | 0.0340792 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0338709 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0337323 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0333004 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0327049 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0321769 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0316888 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0315032 |
| MYOF | myoferlin | 0.031481 |
| GOLGA4 | golgin A4 | 0.0301972 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.02994 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0294994 |
| INHBA | inhibin, beta A | 0.0292045 |
| RPL23 | ribosomal protein L23 | 0.0291611 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0289939 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0289707 |
| KIAA0825 | KIAA0825 | 0.028968 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0288129 |
| CLU | clusterin | 0.0287898 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0287799 |
| NEK7 | NIMA-related kinase 7 | 0.0283681 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0280069 |
| PLCB4 | phospholipase C, beta 4 | 0.0277969 |
| CDK6 | cyclin-dependent kinase 6 | 0.0276168 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0272394 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0272154 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0266162 |
| PTEN | phosphatase and tensin homolog | 0.0264137 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0263441 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0262439 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0261343 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0258866 |
| EZR | ezrin | 0.0257848 |
| EPHA4 | EPH receptor A4 | 0.025727 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0255482 |
| TXNRD1 | thioredoxin reductase 1 | 0.0253599 |
| ESM1 | endothelial cell-specific molecule 1 | 0.0251836 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0250375 |
| ANLN | anillin, actin binding protein | 0.0249513 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0245454 |
| RPS12 | ribosomal protein S12 | 0.0245436 |
| RBM25 | RNA binding motif protein 25 | 0.024455 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.10451 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0814033 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0786574 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0780735 |
| FN1 | fibronectin 1 | -0.074566 |
| CDH13 | cadherin 13 | -0.063881 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0569031 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0568997 |
| AUTS2 | autism susceptibility candidate 2 | -0.0554268 |
| PCBP3 | poly(rC) binding protein 3 | -0.0544529 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0503532 |
| SMYD3 | SET and MYND domain containing 3 | -0.0478018 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0444371 |
| FMNL2 | formin-like 2 | -0.0396545 |
| VIM | vimentin | -0.0390597 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0383272 |
| MAP7 | microtubule-associated protein 7 | -0.0355958 |
| SMAD2 | SMAD family member 2 | -0.0348977 |
| CTBP2 | C-terminal binding protein 2 | -0.0346607 |
| SQSTM1 | sequestosome 1 | -0.0341378 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0327605 |
| DENND1A | DENN/MADD domain containing 1A | -0.031583 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0310841 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0304226 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0299851 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0297834 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0294161 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0291258 |
| TENM3 | teneurin transmembrane protein 3 | -0.0282777 |
| UBC | ubiquitin C | -0.02627 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0254956 |
| RPS24 | ribosomal protein S24 | -0.025295 |
| RPL38 | ribosomal protein L38 | -0.0252943 |
| RANBP17 | RAN binding protein 17 | -0.0249542 |
| NCKAP5 | NCK-associated protein 5 | -0.0248252 |
| BMERB1 | bMERB domain containing 1 | -0.0240061 |
| FTL | ferritin, light polypeptide | -0.0238396 |
| S100A10 | S100 calcium binding protein A10 | -0.0236587 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0236403 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0233014 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0232939 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0229179 |
| RAD51B | RAD51 paralog B | -0.0228956 |
| SPAG9 | sperm associated antigen 9 | -0.0224274 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0223834 |
| TMSB10 | thymosin beta 10 | -0.0222673 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0221353 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0221064 |
| RPL31 | ribosomal protein L31 | -0.0217586 |
| PRKCA | protein kinase C, alpha | -0.0211526 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0210507 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0208333 |
| FAM13A | family with sequence similarity 13, member A | -0.0204116 |
| ENO1 | enolase 1, (alpha) | -0.0202329 |
| ZFHX3 | zinc finger homeobox 3 | -0.0200329 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0199017 |
| GNAS | GNAS complex locus | -0.0198153 |
| RPL35A | ribosomal protein L35a | -0.0196751 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0195432 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.01952 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.019513 |
| PDE10A | phosphodiesterase 10A | -0.0194247 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0193099 |
| ZNF638 | zinc finger protein 638 | -0.0192596 |
| GRB10 | growth factor receptor-bound protein 10 | -0.019256 |
| RPS29 | ribosomal protein S29 | -0.0192044 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0191988 |
| CTSL | cathepsin L | -0.0191853 |
| SLK | STE20-like kinase | -0.0191542 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.019074 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0190234 |
| HDAC4 | histone deacetylase 4 | -0.0190221 |
| FLNB | filamin B, beta | -0.0190167 |
| RAB31 | RAB31, member RAS oncogene family | -0.0188816 |
| MPZL1 | myelin protein zero-like 1 | -0.0188536 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0187105 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.018596 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0184307 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0179215 |
| ACVR1 | activin A receptor, type I | -0.01792 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0179053 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0178718 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.017847 |
| RPLP0 | ribosomal protein, large, P0 | -0.0178422 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0177136 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.017593 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0175282 |
| FNIP1 | folliculin interacting protein 1 | -0.0175231 |
| NBEAL1 | neurobeachin-like 1 | -0.017431 |
| USP3 | ubiquitin specific peptidase 3 | -0.0173993 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0172983 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0172487 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0172069 |
| CLMP | CXADR-like membrane protein | -0.0171205 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0169615 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0169105 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0169054 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0164727 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0164525 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0164521 |
