| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verteporfin perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Verteporfin_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | 0.108465 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0940814 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0891248 |
| EFNA5 | ephrin-A5 | 0.0846018 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0753381 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0688794 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0648711 |
| SYT1 | synaptotagmin I | 0.0638311 |
| FOXK2 | forkhead box K2 | 0.0606531 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0596673 |
| CANX | calnexin | 0.0590257 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0586246 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0578904 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0566983 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0554161 |
| FAM117B | family with sequence similarity 117, member B | 0.0550632 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0547176 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0542402 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0534902 |
| RPLP1 | ribosomal protein, large, P1 | 0.0524917 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0512667 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0508399 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0504819 |
| CDH13 | cadherin 13 | 0.0501759 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0488436 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0488063 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0473238 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0462991 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0459011 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0447665 |
| OSMR | oncostatin M receptor | 0.0440318 |
| PEG10 | paternally expressed 10 | 0.0435904 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0433142 |
| PDE10A | phosphodiesterase 10A | 0.0431385 |
| FAT1 | FAT atypical cadherin 1 | 0.0421889 |
| HMGA2 | high mobility group AT-hook 2 | 0.0418315 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0416327 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0408148 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0407659 |
| TPR | translocated promoter region, nuclear basket protein | 0.040177 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0400904 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0399406 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0395816 |
| RPL37A | ribosomal protein L37a | 0.0393327 |
| BPTF | bromodomain PHD finger transcription factor | 0.0383041 |
| RPS8 | ribosomal protein S8 | 0.037689 |
| VCL | vinculin | 0.0374144 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.037392 |
| RLF | rearranged L-myc fusion | 0.0371955 |
| ZNF292 | zinc finger protein 292 | 0.0366486 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.035766 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0348821 |
| SBF2 | SET binding factor 2 | 0.034744 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0345665 |
| PHF21A | PHD finger protein 21A | 0.0345356 |
| NAV1 | neuron navigator 1 | 0.0345112 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0342973 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0341701 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0338911 |
| FLNB | filamin B, beta | 0.0336923 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0334459 |
| ZNF148 | zinc finger protein 148 | 0.0321899 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0319619 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0313679 |
| GNAS | GNAS complex locus | 0.031061 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0310609 |
| RAB10 | RAB10, member RAS oncogene family | 0.0308908 |
| PRELID2 | PRELI domain containing 2 | 0.030852 |
| GRB10 | growth factor receptor-bound protein 10 | 0.030705 |
| RPS19 | ribosomal protein S19 | 0.0304989 |
| CD2AP | CD2-associated protein | 0.0303348 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0299634 |
| MYOF | myoferlin | 0.0292497 |
| PGK1 | phosphoglycerate kinase 1 | 0.0286825 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0282783 |
| RPS27A | ribosomal protein S27a | 0.0282219 |
| RPS3 | ribosomal protein S3 | 0.0275234 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | 0.0269431 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0263474 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0261143 |
| TENM3 | teneurin transmembrane protein 3 | 0.0258683 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0255052 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0254066 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0252952 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0250056 |
| RPL26 | ribosomal protein L26 | 0.0249337 |
| FN1 | fibronectin 1 | 0.023943 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0229559 |
| ENO1 | enolase 1, (alpha) | 0.0227106 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0223033 |
| RPLP0 | ribosomal protein, large, P0 | 0.0222867 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0218883 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0215946 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0211218 |
| NPAS2 | neuronal PAS domain protein 2 | 0.021086 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.020902 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0207068 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0206147 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0204671 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0204596 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.154527 |
| PTK2 | protein tyrosine kinase 2 | -0.0932124 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0773251 |
| VIM | vimentin | -0.0715029 |
| NDRG1 | N-myc downstream regulated 1 | -0.0675595 |
| OGA | O-GlcNAcase | -0.0593092 |
| ANKRD11 | ankyrin repeat domain 11 | -0.05645 |
| GOLGA4 | golgin A4 | -0.0540924 |
| TPM3 | tropomyosin 3 | -0.0518866 |
| FMNL2 | formin-like 2 | -0.0509947 |
| LAMB3 | laminin, beta 3 | -0.0502564 |
| STC1 | stanniocalcin 1 | -0.0487722 |
| B2M | beta-2-microglobulin | -0.0480107 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0466918 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0463603 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0452053 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0426759 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0423586 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0417749 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0416435 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0414048 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0407163 |
| MEF2A | myocyte enhancer factor 2A | -0.040491 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0404862 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0398103 |
| RPS16 | ribosomal protein S16 | -0.0394205 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0389738 |
| SPAG9 | sperm associated antigen 9 | -0.0389698 |
| LOXL2 | lysyl oxidase-like 2 | -0.0387491 |
| AHNAK | AHNAK nucleoprotein | -0.038634 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0374271 |
| H3-3B | H3.3 histone B | -0.0374074 |
| ITGA6 | integrin, alpha 6 | -0.0372396 |
| EZR | ezrin | -0.0372123 |
| RBM25 | RNA binding motif protein 25 | -0.0368675 |
| TPI1 | triosephosphate isomerase 1 | -0.0367855 |
| FOSL1 | FOS-like antigen 1 | -0.0359136 |
| SEPTIN2 | septin 2 | -0.03524 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0349384 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0344596 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0342159 |
| IER3 | immediate early response 3 | -0.0339915 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0339861 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0335335 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0335072 |
| USP8 | ubiquitin specific peptidase 8 | -0.0328238 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0327478 |
| SMYD3 | SET and MYND domain containing 3 | -0.0327136 |
| EP400 | E1A binding protein p400 | -0.0325636 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0324774 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0323657 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0320104 |
| STK24 | serine/threonine kinase 24 | -0.0317604 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0310363 |
| OXSR1 | oxidative stress responsive 1 | -0.0309947 |
| TOP1 | topoisomerase (DNA) I | -0.0307637 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0307296 |
| RPL35A | ribosomal protein L35a | -0.0306932 |
| HELZ | helicase with zinc finger | -0.0306668 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0303201 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0295915 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0291814 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.028962 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0288697 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0286138 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0285856 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0279641 |
| RNF145 | ring finger protein 145 | -0.0276259 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0276191 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0273563 |
| RHEB | Ras homolog enriched in brain | -0.027056 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0269784 |
| POTEF | POTE ankyrin domain family, member F | -0.0268051 |
| GLG1 | golgi glycoprotein 1 | -0.0266269 |
| MSN | moesin | -0.0265979 |
| COPA | coatomer protein complex, subunit alpha | -0.0261744 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0261043 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.026066 |
| VMP1 | vacuole membrane protein 1 | -0.0258315 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0257992 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0256845 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0256445 |
| ERBIN | erbb2 interacting protein | -0.0254989 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0253876 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0253251 |
| IPO7 | importin 7 | -0.0253068 |
| MYO6 | myosin VI | -0.0251491 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0247299 |
| UVRAG | UV radiation resistance associated | -0.0246256 |
| FBXO34 | F-box protein 34 | -0.0244844 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0244324 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0243448 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0240331 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0236283 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0233792 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0232823 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.022778 |
| TMSB10 | thymosin beta 10 | -0.0227121 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0226811 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0226216 |
