| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verteporfin perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Verteporfin_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.156187 |
| PEG10 | paternally expressed 10 | 0.135666 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0675504 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0590359 |
| SFRP4 | secreted frizzled-related protein 4 | 0.0576714 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0515655 |
| NTM | neurotrimin | 0.050632 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0484562 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0429609 |
| FBL | fibrillarin | 0.0403256 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0402329 |
| HMGB1 | high mobility group box 1 | 0.0399247 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0377552 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0375577 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0353183 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0348084 |
| H1-4 | H1.4 linker histone, cluster member | 0.0333985 |
| RBM25 | RNA binding motif protein 25 | 0.0327931 |
| LRRN3 | leucine rich repeat neuronal 3 | 0.0304359 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0303278 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0299232 |
| TENM2 | teneurin transmembrane protein 2 | 0.0291653 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0289004 |
| BEX3 | brain expressed X-linked 3 | 0.0284952 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0279326 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0277337 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0271496 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0267773 |
| GPC4 | glypican 4 | 0.0262606 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | 0.0258233 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0247593 |
| TGFB2 | transforming growth factor, beta 2 | 0.0245632 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0245031 |
| CCAR1 | cell division cycle and apoptosis regulator 1 | 0.0240844 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0239241 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0234132 |
| RTF1 | Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 0.0232238 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0231024 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0229801 |
| CLSPN | claspin | 0.0227093 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0226258 |
| CANX | calnexin | 0.0224257 |
| DENND2B | DENN domain containing 2B | 0.0223489 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0222818 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0221757 |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) | 0.0219671 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.0218412 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0217984 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0215851 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 0.0213068 |
| TPM3 | tropomyosin 3 | 0.0212033 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0211929 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | 0.0211584 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0210418 |
| CYB5D2 | cytochrome b5 domain containing 2 | 0.0208326 |
| MBIP | MAP3K12 binding inhibitory protein 1 | 0.0208287 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0207956 |
| RPL23A | ribosomal protein L23a | 0.0207306 |
| CDK8 | cyclin-dependent kinase 8 | 0.0206652 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0203224 |
| CCNC | cyclin C | 0.0203177 |
| CALR | calreticulin | 0.0200186 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0198258 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0198244 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0195722 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0194451 |
| TMSB4X | thymosin beta 4, X-linked | 0.0193949 |
| PRR16 | proline rich 16 | 0.0193098 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.019195 |
| SLC44A5 | solute carrier family 44, member 5 | 0.0191827 |
| PLPP1 | phospholipid phosphatase 1 | 0.0189779 |
| HCFC1 | host cell factor C1 | 0.0189619 |
| BRD7 | bromodomain containing 7 | 0.0188877 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.0188044 |
| TCF12 | transcription factor 12 | 0.0187319 |
| IL6ST | interleukin 6 signal transducer | 0.0186925 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.0186382 |
| CDH13 | cadherin 13 | 0.0186352 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | 0.0184718 |
| DSEL | dermatan sulfate epimerase-like | 0.0183938 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.0183544 |
| EMP1 | epithelial membrane protein 1 | 0.0181436 |
| URI1 | URI1, prefoldin-like chaperone | 0.0180527 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.017991 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0179685 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0179546 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0179343 |
| PPTC7 | PTC7 protein phosphatase homolog (S. cerevisiae) | 0.0179026 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0178756 |
| UBTF | upstream binding transcription factor, RNA polymerase I | 0.0177387 |
| XPO1 | exportin 1 | 0.0177031 |
| ZFR | zinc finger RNA binding protein | 0.0175991 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0175972 |
| TM7SF3 | transmembrane 7 superfamily member 3 | 0.0174286 |
| UBE3A | ubiquitin protein ligase E3A | 0.0173874 |
| SPAG9 | sperm associated antigen 9 | 0.0173766 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | 0.0172949 |
| RPS21 | ribosomal protein S21 | 0.0172851 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0171993 |
| CENPP | centromere protein P | 0.0171525 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.119415 |
| FNDC3B | fibronectin type III domain containing 3B | -0.103199 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0938507 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0784161 |
| CADM2 | cell adhesion molecule 2 | -0.075144 |
| FOXP2 | forkhead box P2 | -0.0751318 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.073218 |
| ENAH | enabled homolog (Drosophila) | -0.0636326 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0615063 |
| PGK1 | phosphoglycerate kinase 1 | -0.0564203 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0561485 |
| H1-0 | H1.0 linker histone | -0.055131 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0514553 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0509626 |
| VIM | vimentin | -0.0499505 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0495695 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0487056 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0477892 |
| SRPK2 | SRSF protein kinase 2 | -0.0466047 |
| DST | dystonin | -0.0455252 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0446772 |
| PARD3 | par-3 family cell polarity regulator | -0.043234 |
| AHNAK | AHNAK nucleoprotein | -0.0431095 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0423801 |
| GNAS | GNAS complex locus | -0.0420796 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0418541 |
| RASAL2 | RAS protein activator like 2 | -0.0409583 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0408521 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0402637 |
| TENM3 | teneurin transmembrane protein 3 | -0.0391962 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0388028 |
| SIK3 | SIK family kinase 3 | -0.0387558 |
| BPTF | bromodomain PHD finger transcription factor | -0.0387365 |
| TMSB10 | thymosin beta 10 | -0.0367271 |
| CAVIN1 | caveolae associated protein 1 | -0.0364542 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0363664 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.036153 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0359273 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0356647 |
| HDAC9 | histone deacetylase 9 | -0.0349424 |
| SMYD3 | SET and MYND domain containing 3 | -0.0341358 |
| NHSL1 | NHS-like 1 | -0.0340242 |
| RPS16 | ribosomal protein S16 | -0.0339405 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0338841 |
| EVI5 | ecotropic viral integration site 5 | -0.0336293 |
| LDHA | lactate dehydrogenase A | -0.0333105 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0330814 |
| PHF3 | PHD finger protein 3 | -0.0330368 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0329321 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0328328 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0327829 |
| PHF21A | PHD finger protein 21A | -0.0323711 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0323402 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0320289 |
| FBXO11 | F-box protein 11 | -0.0314867 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0313451 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.031234 |
| YBX1 | Y box binding protein 1 | -0.0311072 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0308169 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0307865 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0306494 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0306416 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0306302 |
| COL3A1 | collagen, type III, alpha 1 | -0.029848 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0296312 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0293411 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0292296 |
| FLNB | filamin B, beta | -0.0292219 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0292122 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0289596 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | -0.0289378 |
| RLF | rearranged L-myc fusion | -0.0286768 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0285886 |
| RPL37A | ribosomal protein L37a | -0.0282041 |
| RPL26 | ribosomal protein L26 | -0.0280243 |
| TBC1D12 | TBC1 domain family, member 12 | -0.0279795 |
| COL5A2 | collagen, type V, alpha 2 | -0.0278326 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0277089 |
| CDK12 | cyclin-dependent kinase 12 | -0.0273504 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0271047 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0266548 |
| PCBP2 | poly(rC) binding protein 2 | -0.0262454 |
| CEP170 | centrosomal protein 170kDa | -0.0261906 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0261873 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0261864 |
| RPL23 | ribosomal protein L23 | -0.026106 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0259939 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0259778 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | -0.0254592 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0253468 |
| RAB10 | RAB10, member RAS oncogene family | -0.025182 |
| TNPO3 | transportin 3 | -0.0251744 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0251695 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | -0.025009 |
| ZNF292 | zinc finger protein 292 | -0.0248909 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.02488 |
| ANXA2 | annexin A2 | -0.0247154 |
| SYT1 | synaptotagmin I | -0.0245049 |
| PROS1 | protein S (alpha) | -0.0244042 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0243715 |
