| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verteporfin perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Verteporfin_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0709597 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0543562 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0469668 |
| ARF1 | ADP-ribosylation factor 1 | 0.0403969 |
| MKI67 | marker of proliferation Ki-67 | 0.0381863 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0380615 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0377204 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0375534 |
| ECT2 | epithelial cell transforming 2 | 0.0375437 |
| RNF145 | ring finger protein 145 | 0.0368174 |
| DTNA | dystrobrevin, alpha | 0.0367142 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0363664 |
| FOSL1 | FOS-like antigen 1 | 0.0361749 |
| NBAS | neuroblastoma amplified sequence | 0.0359135 |
| TPX2 | TPX2, microtubule-associated | 0.0351184 |
| USP24 | ubiquitin specific peptidase 24 | 0.0343729 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.03421 |
| PGK1 | phosphoglycerate kinase 1 | 0.0335806 |
| HMGA1 | high mobility group AT-hook 1 | 0.0331433 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0329773 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0327977 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0322188 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0318138 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.0309865 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0309785 |
| OXR1 | oxidation resistance 1 | 0.0309736 |
| DSTN | destrin (actin depolymerizing factor) | 0.0308682 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0307774 |
| TMED5 | transmembrane emp24 protein transport domain containing 5 | 0.030505 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.030357 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0300373 |
| KLF6 | Kruppel-like factor 6 | 0.0299636 |
| RPL13A | ribosomal protein L13a | 0.0293553 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0292981 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0291002 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0290352 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0279575 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0277096 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0272598 |
| PRELID2 | PRELI domain containing 2 | 0.0272588 |
| CCNL1 | cyclin L1 | 0.0272445 |
| JAK1 | Janus kinase 1 | 0.0270029 |
| NPTN | neuroplastin | 0.0269856 |
| FAM13B | family with sequence similarity 13, member B | 0.0268887 |
| MORC3 | MORC family CW-type zinc finger 3 | 0.0268187 |
| ZNF292 | zinc finger protein 292 | 0.0266562 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0265376 |
| MORF4L2 | mortality factor 4 like 2 | 0.0265066 |
| ANLN | anillin, actin binding protein | 0.026399 |
| KIF18A | kinesin family member 18A | 0.0261734 |
| RPL5 | ribosomal protein L5 | 0.0261087 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.0260866 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0260075 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0259088 |
| DMXL1 | Dmx-like 1 | 0.0258932 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0256291 |
| RYK | receptor-like tyrosine kinase | 0.0253194 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0251565 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0250909 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0250739 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0249683 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0248711 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0246682 |
| GRB2 | growth factor receptor-bound protein 2 | 0.0246108 |
| RPL27A | ribosomal protein L27a | 0.0244418 |
| HMGB2 | high mobility group box 2 | 0.0243559 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0240769 |
| SEPTIN9 | septin 9 | 0.0240542 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0239425 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0239284 |
| SEC24A | SEC24 family member A | 0.0238129 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0238088 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0236626 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0235985 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0233985 |
| KIAA1958 | KIAA1958 | 0.023393 |
| ITM2C | integral membrane protein 2C | 0.0232712 |
| WWC1 | WW and C2 domain containing 1 | 0.0231355 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.023035 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.0229862 |
| DEPDC1 | DEP domain containing 1 | 0.0228023 |
| ZNHIT6 | zinc finger, HIT-type containing 6 | 0.0226131 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0223672 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0223359 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0222901 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0221987 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.022113 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0221035 |
| PTMS | parathymosin | 0.0220766 |
| ATP13A3 | ATPase type 13A3 | 0.0220583 |
| SNX3 | sorting nexin 3 | 0.0220487 |
| MRPS35 | mitochondrial ribosomal protein S35 | 0.0220419 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | 0.0219829 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0219587 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0219437 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0218671 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0218424 |
| CSNK1E | casein kinase 1, epsilon | 0.0218413 |
| MMP12 | matrix metallopeptidase 12 | 0.0217499 |
| CAMLG | calcium modulating ligand | 0.0216659 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.244254 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.183145 |
| NDRG1 | N-myc downstream regulated 1 | -0.115613 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.093645 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0811261 |
| COL6A3 | collagen, type VI, alpha 3 | -0.077659 |
| AHNAK | AHNAK nucleoprotein | -0.0762433 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0726082 |
| TMSB10 | thymosin beta 10 | -0.0677691 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0626875 |
| CDK6 | cyclin-dependent kinase 6 | -0.060974 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0607097 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0571256 |
| UBC | ubiquitin C | -0.0550231 |
| SDC4 | syndecan 4 | -0.0524547 |
| EFNA5 | ephrin-A5 | -0.0523707 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0507692 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0505104 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.049574 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0479569 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0467433 |
| RNF24 | ring finger protein 24 | -0.0444126 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0438779 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0434729 |
| LOX | lysyl oxidase | -0.0430833 |
| EGFR | epidermal growth factor receptor | -0.0429604 |
| H3-3B | H3.3 histone B | -0.0426978 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0425956 |
| SMYD3 | SET and MYND domain containing 3 | -0.0424867 |
| GLIS3 | GLIS family zinc finger 3 | -0.0418361 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0416736 |
| EXOC4 | exocyst complex component 4 | -0.0415295 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0403912 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0402506 |
| SMAD3 | SMAD family member 3 | -0.0396942 |
| ASPH | aspartate beta-hydroxylase | -0.0396738 |
| NRP1 | neuropilin 1 | -0.039613 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0395042 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0394215 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0386369 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0383362 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0371976 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0367029 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0362697 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0362619 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0354945 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0354626 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.034959 |
| CUL4B | cullin 4B | -0.0348581 |
| RUNX1 | runt-related transcription factor 1 | -0.0348302 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0338746 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0335879 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0335632 |
| FAM13A | family with sequence similarity 13, member A | -0.0331957 |
| CALD1 | caldesmon 1 | -0.032947 |
| IL6 | interleukin 6 | -0.032845 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0327979 |
| ZNF207 | zinc finger protein 207 | -0.0324572 |
| HELZ | helicase with zinc finger | -0.0318731 |
| DYM | dymeclin | -0.0318134 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0316784 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0315377 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0314778 |
| COL5A1 | collagen, type V, alpha 1 | -0.0312863 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0311261 |
| METTL15 | methyltransferase like 15 | -0.0309825 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0309501 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0309221 |
| USP34 | ubiquitin specific peptidase 34 | -0.0308044 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0307793 |
| LONP2 | lon peptidase 2, peroxisomal | -0.030571 |
| FN1 | fibronectin 1 | -0.0296554 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0295782 |
| PMM2 | phosphomannomutase 2 | -0.0295753 |
| DENND4A | DENN/MADD domain containing 4A | -0.0294826 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0293816 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0293384 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0292573 |
| GIGYF2 | GRB10 interacting GYF protein 2 | -0.0288666 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0288365 |
| TXNIP | thioredoxin interacting protein | -0.0288309 |
| SRPK2 | SRSF protein kinase 2 | -0.0286531 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0282215 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0282037 |
| OGA | O-GlcNAcase | -0.0281519 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0281347 |
| CCNI | cyclin I | -0.0279918 |
| CANX | calnexin | -0.0278375 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0277422 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0276784 |
| AUTS2 | autism susceptibility candidate 2 | -0.0276258 |
| POTEF | POTE ankyrin domain family, member F | -0.0275633 |
| NKTR | natural killer cell triggering receptor | -0.0273326 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0269539 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0269475 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0267229 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0267101 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | -0.0264215 |
| RBM25 | RNA binding motif protein 25 | -0.0263669 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | -0.0263257 |
