| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verteporfin perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Verteporfin_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.049391 |
| GOLGA4 | golgin A4 | 0.0481049 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0477872 |
| TPX2 | TPX2, microtubule-associated | 0.0360337 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0351244 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.03502 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.031967 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.031012 |
| RPL23 | ribosomal protein L23 | 0.0305233 |
| CENPF | centromere protein F, 350/400kDa | 0.0299571 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0297199 |
| RPL26 | ribosomal protein L26 | 0.0294152 |
| RPS17 | ribosomal protein S17 | 0.0283467 |
| SRP54 | signal recognition particle 54kDa | 0.0277667 |
| RBM39 | RNA binding motif protein 39 | 0.0264779 |
| ANLN | anillin, actin binding protein | 0.026137 |
| PTMA | prothymosin, alpha | 0.0260803 |
| RPS12 | ribosomal protein S12 | 0.0238469 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0229088 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0223478 |
| NOP58 | NOP58 ribonucleoprotein | 0.0222691 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0221164 |
| HELZ | helicase with zinc finger | 0.0218114 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0214723 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0214355 |
| DIAPH3 | diaphanous-related formin 3 | 0.0211071 |
| RPL37A | ribosomal protein L37a | 0.0205221 |
| RAB33B | RAB33B, member RAS oncogene family | 0.0204424 |
| RPL7 | ribosomal protein L7 | 0.0201874 |
| TXNRD1 | thioredoxin reductase 1 | 0.0201622 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0201523 |
| SET | SET nuclear proto-oncogene | 0.0199814 |
| RPLP2 | ribosomal protein, large, P2 | 0.0197805 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0195504 |
| HMGB2 | high mobility group box 2 | 0.0195354 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0195154 |
| RPL12 | ribosomal protein L12 | 0.0190664 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0189193 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0188523 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0184926 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0181131 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0180901 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0178815 |
| MKI67 | marker of proliferation Ki-67 | 0.017865 |
| RPL9 | ribosomal protein L9 | 0.0178371 |
| RPS3 | ribosomal protein S3 | 0.017668 |
| KIF5B | kinesin family member 5B | 0.017593 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0173623 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0170983 |
| KIF20B | kinesin family member 20B | 0.0167802 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0167088 |
| RPL11 | ribosomal protein L11 | 0.016647 |
| MORF4L2 | mortality factor 4 like 2 | 0.0162813 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0162307 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0162109 |
| TPR | translocated promoter region, nuclear basket protein | 0.0160894 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.016078 |
| PNN | pinin, desmosome associated protein | 0.0160502 |
| RPL35 | ribosomal protein L35 | 0.0159303 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0157238 |
| BRD8 | bromodomain containing 8 | 0.0156828 |
| RPS6 | ribosomal protein S6 | 0.0155969 |
| FAM13A | family with sequence similarity 13, member A | 0.015474 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0154687 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0154282 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0154177 |
| RPLP1 | ribosomal protein, large, P1 | 0.0150983 |
| SUCO | SUN domain containing ossification factor | 0.0150886 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0150246 |
| PHIP | pleckstrin homology domain interacting protein | 0.0149679 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0149505 |
| NUP58 | nucleoporin 58 | 0.0149161 |
| RPL32 | ribosomal protein L32 | 0.0147831 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.014766 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0147012 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0145119 |
| RPS27A | ribosomal protein S27a | 0.0144487 |
| RPS8 | ribosomal protein S8 | 0.0144339 |
| PRC1 | protein regulator of cytokinesis 1 | 0.0142945 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0142843 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0142082 |
| RPS2 | ribosomal protein S2 | 0.0141056 |
| CKAP2L | cytoskeleton associated protein 2-like | 0.0140899 |
| NONO | non-POU domain containing, octamer-binding | 0.0139968 |
| PCBP2 | poly(rC) binding protein 2 | 0.0139273 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0139048 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0138862 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0138791 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0138547 |
| ANXA1 | annexin A1 | 0.0137702 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0137503 |
| TPM3 | tropomyosin 3 | 0.0136097 |
| PPIL4 | peptidylprolyl isomerase (cyclophilin)-like 4 | 0.0135938 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0134741 |
| RACK1 | receptor for activated C kinase 1 | 0.0133852 |
| HJURP | Holliday junction recognition protein | 0.0133494 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.013072 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0130408 |
| AURKA | aurora kinase A | 0.0130397 |
| RPL5 | ribosomal protein L5 | 0.0130361 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.198868 |
| FNDC3B | fibronectin type III domain containing 3B | -0.133473 |
| LDHA | lactate dehydrogenase A | -0.0696181 |
| DST | dystonin | -0.0618164 |
| HMGA2 | high mobility group AT-hook 2 | -0.0611148 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0579863 |
| CD44 | CD44 molecule (Indian blood group) | -0.0575826 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0560381 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0535142 |
| FMNL2 | formin-like 2 | -0.0529251 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0519527 |
| AHNAK | AHNAK nucleoprotein | -0.0510642 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0507602 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0500269 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0484529 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0468431 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.046602 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0464285 |
| POTEF | POTE ankyrin domain family, member F | -0.0462253 |
| SVIL | supervillin | -0.0447197 |
| TMSB10 | thymosin beta 10 | -0.0441425 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0439828 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0432989 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0423433 |
| PKM | pyruvate kinase, muscle | -0.041523 |
| ANGPTL4 | angiopoietin-like 4 | -0.0415062 |
| RAI14 | retinoic acid induced 14 | -0.0411262 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0405096 |
| FMN1 | formin 1 | -0.0385888 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.037305 |
| PRKCA | protein kinase C, alpha | -0.0366668 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0362414 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0360372 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.035902 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0356163 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0346047 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0345092 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0344597 |
| SMYD3 | SET and MYND domain containing 3 | -0.0335984 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0335802 |
| ANXA2 | annexin A2 | -0.0334736 |
| FLNB | filamin B, beta | -0.0333921 |
| ATM | ATM serine/threonine kinase | -0.0332782 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0332432 |
| NALCN | sodium leak channel, non selective | -0.033201 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0330211 |
| PRSS23 | protease, serine, 23 | -0.0314607 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0312593 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0309389 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0306396 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0304294 |
| RIGI | RNA sensor RIG-I | -0.0303902 |
| PRR16 | proline rich 16 | -0.0298292 |
| OSMR | oncostatin M receptor | -0.0296044 |
| ERBIN | erbb2 interacting protein | -0.0294843 |
| MAP1B | microtubule-associated protein 1B | -0.0290318 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0289922 |
| ATXN1 | ataxin 1 | -0.0284856 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0282651 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0282056 |
| PODXL | podocalyxin-like | -0.0278507 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0277699 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0273328 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0262766 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0259768 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0259478 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0258297 |
| PCED1B | PC-esterase domain containing 1B | -0.025573 |
| SMAD3 | SMAD family member 3 | -0.0254219 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0253195 |
| EGFR | epidermal growth factor receptor | -0.0252731 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0249048 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0244143 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0243739 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0243143 |
| AEBP2 | AE binding protein 2 | -0.0243009 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | -0.023939 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0237367 |
| RNF213 | ring finger protein 213 | -0.0234502 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0234007 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0230401 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0229895 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0229634 |
| LMO7 | LIM domain 7 | -0.0229265 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0227001 |
| ACTG1 | actin gamma 1 | -0.0226211 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0225584 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0225556 |
| ABR | active BCR-related | -0.0224202 |
| INTS6 | integrator complex subunit 6 | -0.0223824 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.022273 |
| GPC6 | glypican 6 | -0.0222221 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0219685 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0216911 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0216546 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0215226 |
| MYOF | myoferlin | -0.0214827 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0213662 |
| ENO1 | enolase 1, (alpha) | -0.0213464 |
| NAV3 | neuron navigator 3 | -0.0206071 |
