| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Verteporfin perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Verteporfin_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.218775 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.12429 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.122569 |
| MT2A | metallothionein 2A | 0.0935014 |
| HLA-B | major histocompatibility complex, class I, B | 0.0723227 |
| RPS12 | ribosomal protein S12 | 0.0655653 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0655551 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0621423 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0580674 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0569711 |
| RACK1 | receptor for activated C kinase 1 | 0.0495217 |
| TXNIP | thioredoxin interacting protein | 0.0482505 |
| STC2 | stanniocalcin 2 | 0.0473135 |
| RPS6 | ribosomal protein S6 | 0.0446927 |
| RPL26 | ribosomal protein L26 | 0.0446508 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0402077 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0400445 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0396716 |
| RPL23 | ribosomal protein L23 | 0.0393577 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0375781 |
| VIM | vimentin | 0.0368939 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0363282 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0361567 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0355182 |
| OSMR | oncostatin M receptor | 0.0352523 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0346147 |
| CANX | calnexin | 0.033365 |
| RPL9 | ribosomal protein L9 | 0.0330006 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0321904 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0320986 |
| DUSP5 | dual specificity phosphatase 5 | 0.0319917 |
| RPL12 | ribosomal protein L12 | 0.03188 |
| HMGA1 | high mobility group AT-hook 1 | 0.0309502 |
| NDRG1 | N-myc downstream regulated 1 | 0.0303172 |
| GOLGA4 | golgin A4 | 0.0291302 |
| PTMA | prothymosin, alpha | 0.0287773 |
| RPS3 | ribosomal protein S3 | 0.0284713 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0276117 |
| SMOX | spermine oxidase | 0.0273448 |
| ANGPTL4 | angiopoietin-like 4 | 0.0272893 |
| RRBP1 | ribosome binding protein 1 | 0.0270351 |
| IL6ST | interleukin 6 signal transducer | 0.026851 |
| PELO | pelota homolog (Drosophila) | 0.0265784 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0264057 |
| SDC4 | syndecan 4 | 0.0263749 |
| TPI1 | triosephosphate isomerase 1 | 0.0258617 |
| VEGFA | vascular endothelial growth factor A | 0.0258325 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0257199 |
| RPS19 | ribosomal protein S19 | 0.0256924 |
| RBM25 | RNA binding motif protein 25 | 0.025354 |
| RPL37 | ribosomal protein L37 | 0.0251437 |
| TPM3 | tropomyosin 3 | 0.0248739 |
| RPL36 | ribosomal protein L36 | 0.0246004 |
| CD44 | CD44 molecule (Indian blood group) | 0.0242249 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0236936 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0234869 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0234343 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0234007 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0229436 |
| RPL37A | ribosomal protein L37a | 0.022582 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0222882 |
| TGM2 | transglutaminase 2 | 0.0222178 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0221899 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0221679 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.022153 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.021808 |
| RPL31 | ribosomal protein L31 | 0.0216891 |
| EGR1 | early growth response 1 | 0.0214232 |
| RPS27A | ribosomal protein S27a | 0.021288 |
| RPS2 | ribosomal protein S2 | 0.0210849 |
| RPS8 | ribosomal protein S8 | 0.0204812 |
| UBXN4 | UBX domain protein 4 | 0.020382 |
| RPS27 | ribosomal protein S27 | 0.0202568 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0201503 |
| HDGF | hepatoma-derived growth factor | 0.0198429 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0196118 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0195931 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0188864 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0188648 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0185327 |
| SEPTIN9 | septin 9 | 0.018337 |
| TOP1 | topoisomerase (DNA) I | 0.0182488 |
| FAM20C | family with sequence similarity 20, member C | 0.0181652 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0180535 |
| PNN | pinin, desmosome associated protein | 0.0175812 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0175539 |
| SLTM | SAFB-like, transcription modulator | 0.0175526 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0175168 |
| KIF5B | kinesin family member 5B | 0.017503 |
| RPS17 | ribosomal protein S17 | 0.0174442 |
| MSN | moesin | 0.0174319 |
| B2M | beta-2-microglobulin | 0.017294 |
| RPL5 | ribosomal protein L5 | 0.0169577 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0169115 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0167084 |
| CENPF | centromere protein F, 350/400kDa | 0.0165493 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0165306 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0164999 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0164242 |
| RPL7 | ribosomal protein L7 | 0.0161623 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.107961 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.103093 |
| NRG1 | neuregulin 1 | -0.0897172 |
| HMGA2 | high mobility group AT-hook 2 | -0.0767377 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0637249 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0538893 |
| PTK2 | protein tyrosine kinase 2 | -0.0523673 |
| SQSTM1 | sequestosome 1 | -0.0519358 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0464917 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0461212 |
| PGK1 | phosphoglycerate kinase 1 | -0.0438192 |
| QKI | QKI, KH domain containing, RNA binding | -0.0429518 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0422786 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0404221 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0402465 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0400891 |
| S100A10 | S100 calcium binding protein A10 | -0.039466 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0377076 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0371792 |
| RHEB | Ras homolog enriched in brain | -0.0356094 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0354522 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0351139 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0350024 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0349757 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0342911 |
| USP34 | ubiquitin specific peptidase 34 | -0.0337918 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0333565 |
| SYT1 | synaptotagmin I | -0.0325012 |
| PARD3 | par-3 family cell polarity regulator | -0.0320607 |
| RASAL2 | RAS protein activator like 2 | -0.0318881 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0314495 |
| SPAG9 | sperm associated antigen 9 | -0.0314477 |
| GLIS3 | GLIS family zinc finger 3 | -0.0311593 |
| SETD5 | SET domain containing 5 | -0.0310691 |
| DENND5B | DENN/MADD domain containing 5B | -0.0308498 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0308268 |
| COG5 | component of oligomeric golgi complex 5 | -0.0303478 |
| TFG | TRK-fused gene | -0.0299457 |
| JMJD1C | jumonji domain containing 1C | -0.0294539 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0290311 |
| HELZ | helicase with zinc finger | -0.0290294 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0287459 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0286061 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0280272 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0279509 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0279252 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0272661 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0272511 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0271723 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0271491 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0270568 |
| NEK7 | NIMA-related kinase 7 | -0.0268535 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0261925 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.02615 |
| RUNX1 | runt-related transcription factor 1 | -0.0260951 |
| SRPK2 | SRSF protein kinase 2 | -0.0258947 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0257666 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0256173 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0254831 |
| DNM1L | dynamin 1-like | -0.0253559 |
| FBXO11 | F-box protein 11 | -0.0253154 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0251435 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.0251316 |
| ERBIN | erbb2 interacting protein | -0.0249143 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0248772 |
| ITGA1 | integrin, alpha 1 | -0.024743 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0245359 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0242633 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0236088 |
| RLF | rearranged L-myc fusion | -0.0235189 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0234561 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0233425 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0232847 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0231775 |
| H1-0 | H1.0 linker histone | -0.0231375 |
| NUMB | numb homolog (Drosophila) | -0.0231231 |
| NAV2 | neuron navigator 2 | -0.0228858 |
| NOP58 | NOP58 ribonucleoprotein | -0.0228825 |
| TMSB4X | thymosin beta 4, X-linked | -0.0227127 |
| SEC24D | SEC24 family member D | -0.022704 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0226153 |
| LMNA | lamin A/C | -0.0225287 |
| DENND4C | DENN/MADD domain containing 4C | -0.0220935 |
| DIAPH3 | diaphanous-related formin 3 | -0.0220302 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0219418 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0218613 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0218308 |
| ZFR | zinc finger RNA binding protein | -0.0218003 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0217961 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0217805 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0217798 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0217645 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0217625 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.021675 |
| SDCBP | syndecan binding protein (syntenin) | -0.021406 |
| RAI14 | retinoic acid induced 14 | -0.0213702 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0213271 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0212795 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0212536 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0209811 |
