Vertigo Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An abnormal sensation of spinning while the body is actually stationary. (Human Phenotype Ontology, HP_0002321)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D014717
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Genes

168 genes/proteins associated with the disease Vertigo from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.06586
BCL2 B-cell CLL/lymphoma 2 2.04643
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.99076
TNF tumor necrosis factor 1.98182
IL6 interleukin 6 1.94422
FOS FBJ murine osteosarcoma viral oncogene homolog 1.93875
CCL2 chemokine (C-C motif) ligand 2 1.93152
IL1B interleukin 1, beta 1.82831
BAX BCL2-associated X protein 1.79694
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.79503
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.78129
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.73516
ICAM1 intercellular adhesion molecule 1 1.72529
TP53 tumor protein p53 1.6906
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.68676
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.66145
IFNG interferon, gamma 1.66017
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.65181
VEGFA vascular endothelial growth factor A 1.63653
CFLAR CASP8 and FADD-like apoptosis regulator 1.59264
DDIT3 DNA-damage-inducible transcript 3 1.59264
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.57281
JUN jun proto-oncogene 1.56141
SOD2 superoxide dismutase 2, mitochondrial 1.54961
CAT catalase 1.54815
NOS2 nitric oxide synthase 2, inducible 1.53651
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.53431
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.52212
TGFB1 transforming growth factor, beta 1 1.52136
BCL2L1 BCL2-like 1 1.51708
GADD45A growth arrest and DNA-damage-inducible, alpha 1.50776
CALCA calcitonin-related polypeptide alpha 1.49045
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.48993
VCAM1 vascular cell adhesion molecule 1 1.48531
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.48428
HMOX1 heme oxygenase 1 1.48068
NPY neuropeptide Y 1.47556
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.45962
FAS Fas cell surface death receptor 1.45194
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.4332
IL10 interleukin 10 1.42211
GSTP1 glutathione S-transferase pi 1 1.42129
MAPK3 mitogen-activated protein kinase 3 1.41721
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.4164
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.41559
GFAP glial fibrillary acidic protein 1.41478
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.41146
MAPK1 mitogen-activated protein kinase 1 1.40568
CXCL8 chemokine (C-X-C motif) ligand 8 1.39226
MMP9 matrix metallopeptidase 9 1.37733
ALB albumin 1.3736
COL3A1 collagen, type III, alpha 1 1.36648
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.36648
BAK1 BCL2-antagonist/killer 1 1.36076
IL2 interleukin 2 1.35041
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.3388
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.32103
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.31476
CCND1 cyclin D1 1.3103
NOS3 nitric oxide synthase 3 (endothelial cell) 1.30911
MMP2 matrix metallopeptidase 2 1.30727
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.30727
CCNB1 cyclin B1 1.29781
REN renin 1.29688
PRL prolactin 1.29657
FN1 fibronectin 1 1.27966
THBS1 thrombospondin 1 1.27657
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.27039
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.26052
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.25307
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.24935
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.24843
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.24781
MPO myeloperoxidase 1.23837
S100A4 S100 calcium binding protein A4 1.23169
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.22884
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.22436
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.22242
HRH1 histamine receptor H1 1.21599
GAMT guanidinoacetate N-methyltransferase 1.2137
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.20881
PARP1 poly (ADP-ribose) polymerase 1 1.20881
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.20848
S100A11 S100 calcium binding protein A11 1.199
TAGLN transgelin 1.19639
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.19574
BID BH3 interacting domain death agonist 1.19412
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.19412
COL1A1 collagen, type I, alpha 1 1.19179
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 1.18915
GSTA2 glutathione S-transferase alpha 2 1.18489
AVP arginine vasopressin 1.18456
RB1 retinoblastoma 1 1.18424
F2 coagulation factor II (thrombin) 1.18226
IGFBP5 insulin-like growth factor binding protein 5 1.17993
CDK2 cyclin-dependent kinase 2 1.17464
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.17168
SELL selectin L 1.16533
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 1.16434
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.16401
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.16001
EGR1 early growth response 1 1.15797
GSTT1 glutathione S-transferase theta 1 1.15458
ANXA4 annexin A4 1.1529
CYP3A cytochrome P450, family 3, subfamily A 1.14678
PECAM1 platelet/endothelial cell adhesion molecule 1 1.14678
CAPN2 calpain 2, (m/II) large subunit 1.14064
PLAT plasminogen activator, tissue 1.13484
IGF1 insulin-like growth factor 1 (somatomedin C) 1.13279
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.13177
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.12737
CLU clusterin 1.12426
NPPA natriuretic peptide A 1.12426
FGF2 fibroblast growth factor 2 (basic) 1.12288
MARCKS myristoylated alanine-rich protein kinase C substrate 1.12082
SPP1 secreted phosphoprotein 1 1.12048
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.12048
TGFB2 transforming growth factor, beta 2 1.11741
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.11466
CD8A CD8a molecule 1.10907
DCXR dicarbonyl/L-xylulose reductase 1.10907
IL4 interleukin 4 1.10527
ADORA3 adenosine A3 receptor 1.10493
IRF9 interferon regulatory factor 9 1.10493
DUSP1 dual specificity phosphatase 1 1.10459
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.10459
F3 coagulation factor III (thromboplastin, tissue factor) 1.10246
IL12A interleukin 12A 1.09857
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.09646
LCN2 lipocalin 2 1.09506
C3 complement component 3 1.08584
CALB1 calbindin 1, 28kDa 1.07732
CCL3 chemokine (C-C motif) ligand 3 1.07234
CCNA2 cyclin A2 1.07093
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.06881
GSTM1 glutathione S-transferase mu 1 1.06698
CYCS cytochrome c, somatic 1.06625
LCK LCK proto-oncogene, Src family tyrosine kinase 1.06588
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.06588
CP ceruloplasmin (ferroxidase) 1.06515
FMOD fibromodulin 1.0637
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.05757
IL12B interleukin 12B 1.05461
MAPK14 mitogen-activated protein kinase 14 1.052
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 1.05089
COL6A3 collagen, type VI, alpha 3 1.04831
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 1.04126
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.04126
VCAN versican 1.03456
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.03271
GPX1 glutathione peroxidase 1 1.03122
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.03122
PDGFB platelet-derived growth factor beta polypeptide 1.02821
CCL5 chemokine (C-C motif) ligand 5 1.02746
CRP C-reactive protein, pentraxin-related 1.02485
TJP3 tight junction protein 3 1.02188
PER1 period circadian clock 1 1.02151
EGFL6 EGF-like-domain, multiple 6 1.0204
CTGF connective tissue growth factor 1.01739
EPO erythropoietin 1.01549
APAF1 apoptotic peptidase activating factor 1 1.01549
COL18A1 collagen, type XVIII, alpha 1 1.01512
GSK3B glycogen synthase kinase 3 beta 1.01361
EPHX2 epoxide hydrolase 2, cytoplasmic 1.01361
BBC3 BCL2 binding component 3 1.01361
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.01249
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.01212
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 1.01137